教育经历：
2020-2025，中国科学院水生生物研究所，水生生物学，硕博连读。
2016-2020，河南师范大学，水产学院，水族科学与技术，本科。
工作经历：
2025-至今，郑州大学，公共卫生学院，副研究员。
研究方向：
（1）典型新污染物的毒性效应评价及作用机制研究
评估新污染物对代谢转化、神经系统和内分泌干扰等方面的毒性效应，揭示传代/跨代毒性效应和分子机制，为新污染物的毒
性评价和生态健康风险评估提供新的思路。基于上述研究构建适用于新污染物毒性效应预测的有害结局路径，为进一步准确快速预
测和科学评价新污染物对生态环境与人类健康的潜在风险提供理论依据和数据支持。
（2）环境中污染物的暴露水平及生态风险评价
针对代表性水体、土壤中多种污染物开展周期性监测，获取典型污染物暴露水平、空间分布以及季节分布特征。通过多层次风
险评价方法评估其对水生态系统和人类健康的潜在风险，为生态保护和环境管理政策的制定提供科学依据。
代表性论文：
[1] Kaiyu Fu; Biran Zhu; Yumiao Sun; Yuxi Zhou; Hao Pang; Xinxin Ren; Yongyong Guo; Xiongjie Shi; Jian Han; Lihua Yang*; Bingsheng Zhou, 2024. Bis (2-ethylhexyl)-tetrabromophthalate poses a higher exposure risk and induces gender-specific metabolic disruptions in zebrafish liver. Environmental Science & Technology, 58(11):4937-4947.
[2] Kaiyu Fu#; Jianghuan Hua#; Yindan Zhang; Mingpu Du; Jian Han; Na Li; Qiangwei Wang; Lihua Yang*; Ruiwen Li*; Bingsheng Zhou, 2024. Integrated studies on male reproductive toxicity of bis(2-ethylhexyl)-tetrabromophthalate: in Silico, in Vitro, ex Vivo, and in Vivo. Environmental Science & Technology, 58(1):194-206.
[3] Yuxi Zhou; Fan Li; Kaiyu Fu; Yindan Zhang; Na Zheng; Huijia Tang; Zhixiang Xu; Lijun Luo; Jian Han; Lihua Yang*; Bingsheng Zhou*, 2024. Bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate Enhances foxo1-Mediated Lipophagy to Remodel Lipid Metabolism in Zebrafish Liver. Environmental Science & Technology, 58(10):4581-4593.
[4] Yuxi Zhou; Kaiyu Fu; Fan Li; Yindan Zhang; Xinxin Ren; Bingjie Li; Shengmin Wu*; Jian Han*; Lihua Yang; Bingsheng Zhou, 2024. UV-aging process of titanium dioxide nanoparticles aggravates enterohepatic toxicity of bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalat
-e to zebrafish. Science of The Total Environment, 958:178074.
[5] Zhu Biran; Chen Xianglin; Zhang Taotao; Zhang Qianqian; Fu Kaiyu; Hua Jianghuan; Zhang Mengyuan; Qi Qing; Zhao Binbin;
Zhao Min*; Yang Lihua*; Zhou Bingsheng. 2024. Interactions between intestinal microbiota and metabolites in zebrafish larvae exposed to polystyrene nanoplastics: Implications for intestinal health and glycolipid metabolism. Journal of Hazardous Materials. 472:134478.
[6] Yan Biao; Sun Yumiao; Fu Kaiyu; Zhang Yindan; Lei Lei; Men Jun; Guo Yongyong; Wu Shengmin*; Han Jian*; Zhou Bingsheng.
2023. Effects of glyphosate exposure on gut-liver axis:Metabolomic and mechanistic analysis in grass carp (Ctenopharyngodon idellus).
Science of The Total Environment. 902:166062.
[7] Sun Yumiao; Zhou Shanqi; Zhu Biran; Li Fan; Fu Kaiyu; Guo Yongyong; Men Jun; Han Jian; Zhang Wei; Yang Lihua*;
Zhou Bingsheng. 2023. Multi- and Transgenerational Developmental Impairments Are Induced by Decabromodiphenyl Ethane (DBDPE) in
Zebrafish Larvae. Environmental Science and Technology. 57(7):2887-2897.
[8] Zhu Biran; Lei Lei; Sun Yumiao; Shi Xiongjie; Fu Kaiyu; Hua Jianghuan; Martyniuk Christopher J; Han Jian*; Yang Lihua*;
Zhou Bingsheng. 2022. Niclosamide Exposure at Environmentally Relevant Concentrations Efficaciously Inhibited the Growth and
Disturbed the Liver-Gut Axis of Adult Male Zebrafish. Environmental Science and Technology. 56(16):11516-11526.
[9] Zhu Biran#; Lei Lei#; Fu Kaiyu; Zhao Songlin; Hua Jianghuan; Yang Lihua; Han Jian*; Li Rui; Zhou Bingsheng. 2022. Neurotoxicity
of tetrabromobisphenol A and SiO2 nanoparticle co-exposure in zebrafish and barrier function of the embryonic chorion. Science of The
Total Environment. 845:157364.