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Research

The Li Group focuses on cutting-edge areas of modern organic chemistry, with a particular emphasis on the intersection of transition metal catalysis and asymmetric synthesis. Below is a systematic overview of the group's main research directions:

1. Transition Metal-Catalyzed C–H Activation

  • Development of novel directing group strategies for regioselective and stereoselective functionalization of inert C–H bonds

  • Transient directing group approaches to improve atom economy

2. Asymmetric Catalysis

  • Chiral ligand development: Design of P-stereogenic, axially chiral, and planar chiral ligands

  • Remote stereocontrol: Inducing stereoselectivity at distal positions relative to the metal center

3. Synthesis of Chiral Functional Molecules

  • Targeted construction of chiral materials (OLED emitters, fluorophores)