55. Y. Zhang, H. T. Yau, Y. Deng, Z. Ying, S. Lee, H. Y. Au-Yeung, E. C. M. Tse "Partially Saturated Copper(I) Rotaxane Complexes from Active Template Synthesis Enable O2-to-H2O Reduction under Acidic Conditions" ChemRxiv, 2025, DOI: 10.26434/chemrxiv-2025-jlhq5 [link] 

54. Y. Yao, M. Hu, H. Zhou, S. K.-M. Lai, H. Y. Au-Yeung, "Catenane Hosts for Solid Lithium Chloride Extraction: Selectivity Reversal, Binding Strength and Uptake Kinetic Enhancement via Post-Interlocking Modification" ChemRxiv, 2025, DOI: 10.26434/chemrxiv-2025-w02p9 [link] 

53. Y. Deng, Z. Lu, S. K.-M. Lai, M. P. Tang, X. Mo, S. He, D. L. Phillips, E. C. M. Tse, H. Y. Au-Yeung, "Structural Dependence of Catenand Effect: Thermodynamic and Kinetic Modulation of Catenane Coordination Properties via Ring-size and Exocyclic Substitution Variation", Angew. Chem. Int. Ed. 2025, 64, e202514599 [link] 
Preprint: ChemRxiv, 2024, DOI: 10.26434/chemrxiv-2024-tdjrk [link] 

52. Y. Shi, L. Zhu, Y. Deng, X. Mo, Y. Wang, E. C. M. Tse, H. Y. Au-Yeung, "A Copper(I) Catenane Decorated Metal-Organic Layer as a Heterogenous Catalyst for Dehydrogenative Cross-Coupling", Chem. Eur. J. 2025, e202500866 [link]

Preprint: ChemRxiv, 2024, DOI: 10.26434/chemrxiv-2024-hk44r [link]

51. Y. Deng, X. Mo, K.-M. Lai, S.-C. Haw, H. Y. Au-Yeung, E. C. M. Tse, "Mechanical and Covalent Tailoring of Copper Catenanes for Selective Aqueous Nitrate-to-Ammonia Electrocatalysis" J. Am. Chem. Soc., 2025, 147, 14316–14325 [link]

Preprint: ChemRxiv,  2024, DOI: 10.26434/chemrxiv-2024-xvj01 [link]

highlighted in 材料科学站 (in Chinese) [link]; X-Mol (in Chinese) [link] [link]

49. S. He, M. Quan, L.-P. Yang, H. Y. Au-Yeung, W. Jiang, "Correlating kinetics and thermodynamics of conformational changes in ammonium complexes of a flexible naphthocage", Chem. Sci. 2024, 15, asap [link]
preprint: ChemRxiv, 2023, DOI: 10.26434/chemrxiv-2023-9c2v5 [link] 

48. M. P. Tang, L. Zhu, Y. Deng, Y. Shi, S. K.-M. Lai, X.-Y. Pang, C. Liu, W. Jiang, H. Y. Au-Yeung, "Water and air stable copper(I) complexes of tetracationic catenane ligands for oxidative C-C cross-coupling", Angew. Chem. Int. Ed. 2024, 63, e202405971 [link]

preprint: ChemRxiv, 2023, DOI: 10.26434/chemrxiv-2023-jbd2z [link] 

highlighted in 化学深耕堂 (in Chinese) [link]; X-Mol (in Chinese) [link] [link]

47. Y. Yao, Y. C. Tse, S. K.-M. Lai, Y. Shi, K.-H. Low, H. Y. Au-Yeung, "Dynamic mechanostereochemical switching of a co-conformationally flexible [2]catenane controlled by specific ionic guests", Nat. Commun. 2024, 15, 1952 [link]
preprint: ChemRxiv, 2023, DOI: 10.26434/chemrxiv-2023-jm9nw [link] 

46. Y. C. Tse, H. Y. Au-Yeung, "Catenane and Rotaxane Synthesis from Cucurbit[6]uril-Mediated Azide-Alkyne Cycloaddition", Chem. Asian J., 2023, 18, e202300290 [link]

Special issue celebrating the 60th anniversary of The Chinese University of Hong Kong

45. W. Y. Yau, S. K.-M. Lai, P. Blasco, X. C. Li, K. M. Ng, C. N. Lok, H. Y. Au-Yeung, "Activity-based Fluorescent Imaging of Alcohol Dehydrogenase Activity in Living Cells", Anal. Sens. 2023, e202300012 [link]

44. X. Mo, Y. Deng, S. K.-M. Lai, X. Gao, H.-L. Yu, K.-H. Low, H.-L. Wu, H. Y. Au-Yeung, E. C. M. Tse, "Mechanical Interlocking Enhances the Electrocatalytic Oxygen Reduction Activity and Selectivity of Molecular Copper Complexes", J. Am. Chem. Soc. 2023, 145, 6087-6099 [link] 

preprint: ChemRxiv 2022, DOI: 10.26434/chemrxiv-2022-5sqh3 [link]

highlighted in Nat. Rev. Chem. [link]; X-Mol (in Chinese) [link] [link]

43. M. H. Y. Lau, C.-H. Wong, H. Y. E. Chan, H. Y. Au-Yeung, "Development of Fluorescent Probe for CAG-RNA Repeats" Biosensors, 2022, 12, 1080 [link] 

42. Y. Yao, Y. Deng, L. Kong, H. Y. Au-Yeung, "Efficient Copper(I) Extraction by Ethylenediamine from Stable Catenane Complexes", Eur. J. Inorg. Chem. 2022, 22, e202200271 [link]

Institute Feature: Hong Kong Universities [link]

41. Y. Deng, X. Ren, M. P. Tang, S. K.-M. Lai, A. W. H. Ng, C.-N. Li, H. Y. Au-Yeung, "Differences in dynamics and responsive behavior of homologous hetero[4]rotaxanes derived from cucurbit[6]uril and β-/γ-cyclodextrin", Mater. Today Chem. 2022, 24, 100952 [link]

Special Issue on the occasion of 80th birthday of Sir Fraser Stoddart

40. W. Liu, L. Kong, M. Quan, H. Yao, L. Yang, H. Y. Au-Yeung, W. Jiang, "Selective recognition of methyl viologen by an endo-functionalized naphthobox" Chin. Chem. Lett. 2022, 33, 4896-4899 [link]

39. H. Y. Au-Yeung, Y. Deng, "Distinctive Features and Challenges in Catenane Chemistry", Chem. Sci. 2022, 13, 3315-3334 [link]

38. A. W. H. Ng, S. K.-M. Lai, C.-C. Yee, H. Y. Au-Yeung, "Macrocycle Dynamics in a Branched [8]Catenane Controlled by Three Different Stimuli in Three Different Regions", Angew. Chem. Int. Ed. 2022, 61, e202110200 [link]

highlighted in 化学与材料科学 (in Chinese) [link]; X-MOL (in Chinese) [link] [link]; WileyChem (in Chinese) [link]

37. S. Peng, P. Guo, X. Lin, Y. An, K. H. Sze, M. H. Y. Lau, Z. S. Chen, Q. Wang, W. Li, J. K.-L. Sun, S. Y. Ma, T.-F. Chan, K.-F. Lau, J. C. K. Ngo, K. M. Kwan, C.-H. Wong, S. L. Lam, S. C. Zimmerman, T. Tuccinardi, Z. Zuo, H. Y. Au-Yeung, H.-M. Chow, H. Y. E. Chan, "CAG RNAs induce DNA damage and apoptosis by silencing NUDT16 expression in polyglutamine degeneration" Proc. Natl. Acad. Sci. USA 2021, 118, e2022940118 [link]

36. A. W. H. Ng, Y. H. Leung, H. Y. Au-Yeung, "Dynamics of Mechanically Bonded Macrocycles in Radial Hetero[4]Catenane Isomers", Org. Chem. Front. 2021, 8, 2182-2189 [link]

Macrocycle-based Supramolecular Elements themed collection

35. Y. Deng, S. K.-M. Lai, L. Kong, H. Y. Au-Yeung, "Fine-Tuning of the Optical Output in a Dual Responsive Catenane Switch", Chem. Commun. 2021, 57, 2931-2934 [link]

34. L. Zhu, J. Li, J. Yang, H. Y. Au-Yeung, "Cross Dehydrogenative C–O Coupling Catalysed by a Catenane-Coordinated Copper(I)", Chem. Sci. 2020, 11, 13008-13014 [link]

featured as the journal back cover

33. W.-E. Liu, M. Quan, H. Zhou, L.-P. Yang, H. Y. Au-Yeung, W. Jiang, "Stabilization of the Closed-Ring Isomer of Spiropyran by Amide Naphthotube in Water and Its Application in Naked-Eye Detection of Toxic Paraoxon" ChemPhyChem 2020, 21, 2249-2253 [link]

32. T. S.-C. Tam, Y.-H. Cheng, C.-N. Lok, H. Y. Au-Yeung, W.-X. Ni, X.-L. Wei, K.-M. Ng, "Surface Optimization of Gold Nanoparticle Mass Tags for the Sensitive Detection of Protein Biomarkers via Immuno-Capture LI-MS" Analyst 2020, 145, 6237-6242 [link]

31. Z. H. Yu, C. J. Reinhardt, T. H.‐F. Wong, K. Y. Tong, J. Chan, H. Y. Au‐Yeung, "Activity‐Based Sensing of Ascorbate by Using Copper‐Mediated Oxidative Bond Cleavage", Chem. Eur. J., 2020, 26, 8794-8800 [link]

30. F. K. Tang, Z. H. Yu, T. H.-F. Wong, C. Y.-S. Chung, H. Hirao, H. Y. Au-Yeung, "Fluorescein-Containing Superoxide Probes with a Modular Copper-Based Trigger", ChemPlusChem, 2020, 85, 653-658 [link]

29. H. Y. Au-Yeung, A. W. H. Ng, "Mechanical Interlocking of Macrocycles in Different Sequences", Synlett, 2020, 31, 309-314 [link]

28. Z. L. Xu, P. C. Wang, H. B. Wang, Z. H. Yu, H. Y. Au-Yeung, T. Hirayama, H. Z. Sun, A. X. Yan, "Zinc excess increases cellular demand for iron and decreases tolerance to copper in Escherichia coli", J. Biol. Chem., 2019, 294, 16978-16991 [link]

27. A. W. H. Ng, C.-C. Yee, H. Y. Au-Yeung, "Radial hetero[5]catenanes: Peripheral isomer sequences of the interlocked macrocycles", Angew. Chem. Int. Ed., 2019, 58, 17375-17382 [link]

26. K. Y. Tong, J. Zhao, C.-W. Tse, P.-K. Wan, J. Rong,  H. Y. Au-Yeung, "Selective catecholamine detection in living cells by a copper-mediated oxidative bond cleavage", Chem. Sci., 2019, 10, 8519-8526 [link]

2019 Chemical Science HOT Article Collection
highlighted as the journal front cover

25. J. Y. H. Man, H. Y. Au-Yeung, "Synthesis of a [6]rotaxane with singly threaded γ-cyclodextrins as a single stereoisomer", Beilstein J. Org. Chem., 2019, 15, 1829-1837 [link]

Novel Macrocycles – and Old Ones Doing New Tricks thematic issue

24. W.-E. Liu, Z. Chen, L.-P. Yang, H. Y. Au-Yeung, W. Jiang, "Molecular recognition of organophosphorus compound in water and inhibition of their toxicity to acetylcholinesterase", Chem. Commun., 2019, 55, 9797-9800 [link]

23. C.-C. Yee, A. W. H. Ng, H. Y. Au-Yeung, "Control over the macrocyclisation pathway and product topology in a copper-templated catenane synthesis", Chem. Commun., 2019, 55, 6169-6172 [link]

highlighted as the journal inside front cover

22. H. Hong, A. C. Koon, Z. S. Chen, Y. Wei, Y. An, W. Li, M. H. Y. Lau, K.-F. Lau, J. C. K. Ngo, C.-H. Wong, H. Y. Au-Yeung, S. C. Zimmerman, H. Y. E. Chan, "AQAMAN, a bisamidine-based inhibitor of toxic protein inclusions in neurons, ameliorates cytotoxicity in polyglutamine disease models", J. Biol. Chem., 2019, 294, 2757-2770 [link]

21. A. W. H. Ng, H. Y. Au-Yeung, "Molecular links and knots from naphthalenediimide: a balance of weak interactions" Chem. Asian J., 2019, 14, 1602-1612 [link]

π‐Conjugated Compounds for Molecular Materials special issue

20. V. Venkataramani, T. R. Doeppner, D. Willkommen, C. M. Cahill, Y. Xin, G. Ye, Y. Liu, A. Southon, A. Aron, H. Y. Au-Yeung, X. Huang, D. K. Lahiri, F. Wang, A. I. Bush, G. G. Wulf, P. Ströbel, B. Michalke, J. T. Rogers, "Manganese causes neurotoxiciron accumulation via translational repression of amyloid precursor protein (APP) and H‐ferritin", J. Neurochem., 2018, 147, 831-848 [link]

19. A. W. H. Ng, C.-C. Yee, K. Wang, H. Y. Au-Yeung, "Efficient catenane synthesis by cucurbit[6]uril-mediated azide-alkyne cycloaddition" Beilstein J. Org. Chem., 2018, 14, 1846-1853 [link]

Macrocyclic and Supramolecular Chemistry thematic issue

18. H. Y. Au-Yeung, C.-C. Yee, A. W. H. Ng, K. Hu, "Strategies to assemble catenanes with multiple interlocked macrocycles", Inorg. Chem., 2018, 57, 3475-3485 [link]

Self-Assembled Cages and Macrocycles special issue

16. H. Y. Au-Yeung, C. Y. Chan, K. Y. Tong, Z. H. Yu, "Copper-based reactions in analyte-responsive fluorescent probes for biological applications", J. Inorg. Biochem., 2017, 177, 300-312 [link]

15. M. C. Heffern, H. M. Park, H. Y. Au-Yeung, G. C. Van de Bittner, C. M. Ackerman, A. Stahl, C. J. Chang, "In vivo bioluminescence imaging reveals copper deficiency in a murine model of nonalcoholic fatty liver disease", Proc. Natl. Acad. Sci. USA, 2016, 113, 14219-14224 [link] 

highlighted in Chemical & Engineering News, 94(49), December 19, 2016

14. K. Wang, C.-C. Yee, H. Y. Au-Yeung, "Facile syntheses of [3]-, [4]- and [6]catenanes templated by orthogonal supramolecular interactions", Chem. Sci., 2016, 7, 2787-2792 [link]

13. K.-L. Tong, C.-C. Yee, Y. C. Tse, H. Y. Au-Yeung, "Discoveries from a phenanthroline-based dynamic combinatorial library: catenane from a copper(I) or copper(II) template?", Inorg. Chem. Front., 2016, 3, 348-353 [link]

12. R. H. F. Wong, T. Kwong, K.-H. Yau, H. Y. Au-Yeung, "Real time detection of live microbes using a highly sensitive bioluminescent nitroreductase probe", Chem. Commun., 2015, 51, 4440-4442 [link]

11. H. Y. Au-Yeung, J. Chan, T. Chantarojsiri, C. J. Chang, "Molecular imaging of labile iron(II) pools in living cells with a turn-on fluorescent probe", J. Am. Chem. Soc., 2013, 135, 15165-15173 [link]

10. H. Y. Au-Yeung, E. J. New, C. J. Chang, "A selective reaction-based fluorescent probe for detecting cobalt in living cells", Chem. Commun., 2012, 48, 5268-5270 [link]

9. F. B. L. Cougnon, H. Y. Au-Yeung, G. D. Pantoș, J. K. M. Sanders, "Exploring the formation pathways of donor-acceptor catenanes in aqueous dynamic combinatorial libraries", J. Am. Chem. Soc., 2011, 133, 3198-3207 [link]

8. H. Y. Au-Yeung, G. D. Pantoș, J. K. M. Sanders, "Donor-acceptor dynamic combinatorial catenanes in water: access to unconventional and unexpected structures", J. Org. Chem., 2011, 76, 1257-1268 [link]

7. F. M. Mansfeld, H. Y. Au-Yeung, J. K. M. Sanders, S. Otto, "Dynamic combinatorial chemistry at the phospholipid bilayer interface", J. Syst. Chem., 2010, 1:12 [link]

6. H. Y. Au-Yeung, F. B. L. Cougnon, S. Otto, G. D. Pantoș, J. K. M. Sanders, "Exploiting donor-acceptor interactions in aqueous dynamic combinatorial libraries: exploratory studies of simple systems", Chem. Sci., 2010, 1, 567-574 [link] 

featured as inside front cover

5. H. Y. Au-Yeung, G. D. Pantoș, J. K. M. Sanders, "A water soluble donor-acceptor [2]catenane that can switch between a coplanar and Gemini-sign conformation", Angew. Chem., Int. Ed., 2010, 49, 5331-5334 [link]

3. H. Y. Au-Yeung, G. D. Pantoș, J. K. M. Sanders, "Dynamic combinatorial synthesis of a catenane based on donor-acceptor interactions in water", Proc. Natl. Acad. Sci. USA, 2009, 106, 10466-10470 [link]

highlighted in Nature Chemistry Feb 2009, DOI: 10.1038/nchem.127

1. H. Y. Au-Yeung, C. H. Lam, C.-K. Lam, W.-Y. Wong, H. K. Lee, "Unusual iron(II) and cobalt(II) complexes derived from monodentate arylamido ligands", Inorg. Chem., 2007, 46, 7695-7697 [link]