-
-
Keeping neonatal intestines happy Nat. Immunol. (IF 30.5) Pub Date : 2024-05-02 Stephanie Houston
Serotonin (also known as 5-hydroxytryptamine or 5-HT) controls gut motility, platelet function, mood regulation and has been implicated in inflammatory bowel disease, but its role in the neonatal gut is unclear. In Science Immunology, Sanidad et al. find that 5-HT derived from the microbiota promotes the differentiation of regulatory T (Treg) cells and confers tolerance to dietary antigens and commensal
-
Inflammatory fibroblasts remodeling in colitis Nat. Immunol. (IF 30.5) Pub Date : 2024-05-02 Paula Jauregui
Inflammatory bowel diseases (IBDs) are characterized by waves of relapse and remitting inflammation that lead to the remodeling of the cellular diversity of the gut. In Cell, Paolo Cadinu at al. chart the cellular and spatial structures of the colon in a mouse model of IBD. Using an image-based approach to spatial transcriptomics that can capture thousands of RNA molecules within single cells in their
-
New role for TLR9 Nat. Immunol. (IF 30.5) Pub Date : 2024-05-02 Laurie A. Dempsey
Toll-like receptor 9 (TLR9) is an innate immune sensor that recognizes intracellular double-stranded DNA (dsDNA). In Nature, Jovasevic et al. show that TLR9–NF-κB signaling in specific hippocampal neurons is required for the generation of learning-induced memory formation in mice. Using models of contextual fear conditioning (CFC), the authors show that nuclear non-coding dsDNA fragments appear within
-
Predictability of B cell clonal persistence and immunosurveillance in breast cancer Nat. Immunol. (IF 30.5) Pub Date : 2024-05-02 Stephen-John Sammut, Jacob D. Galson, Ralph Minter, Bo Sun, Suet-Feung Chin, Leticia De Mattos-Arruda, Donna K. Finch, Sebastian Schätzle, Jorge Dias, Oscar M. Rueda, Joan Seoane, Jane Osbourn, Carlos Caldas, Rachael J. M. Bashford-Rogers
-
Coordinated chemokine expression defines macrophage subsets across tissues Nat. Immunol. (IF 30.5) Pub Date : 2024-05-02 Xin Li, Arlind B. Mara, Shawn C. Musial, Fred W. Kolling, Sophie L. Gibbings, Nikita Gerebtsov, Claudia V. Jakubzick
-
Temporal dynamics and genomic programming of plasma cell fates Nat. Immunol. (IF 30.5) Pub Date : 2024-05-02 Godhev Kumar Manakkat Vijay, Ming Zhou, Kairavee Thakkar, Abigail Rothrauff, Amanpreet Singh Chawla, Dianyu Chen, Louis Chi-Wai Lau, Peter Habib Gerges, Kashish Chetal, Prabal Chhibbar, Jingyu Fan, Jishnu Das, Alok Joglekar, Lisa Borghesi, Nathan Salomonis, Heping Xu, Harinder Singh
-
The ouroboros of autoimmunity Nat. Immunol. (IF 30.5) Pub Date : 2024-05-02 Jean-Laurent Casanova, Jessica Peel, Jean Donadieu, Anna-Lena Neehus, Anne Puel, Paul Bastard
-
Baseline JAK–STAT signaling maintains immune cell homeostasis Nat. Immunol. (IF 30.5) Pub Date : 2024-04-29
-
Human SHARPIN deficiency is linked to inborn errors of cell death Nat. Immunol. (IF 30.5) Pub Date : 2024-04-29
-
Sepsis-trained macrophages promote antitumoral tissue-resident T cells Nat. Immunol. (IF 30.5) Pub Date : 2024-04-29 Alexis Broquet, Victor Gourain, Thomas Goronflot, Virginie Le Mabecque, Debajyoti Sinha, Mitra Ashayeripanah, Cédric Jacqueline, Pierre Martin, Marion Davieau, Lea Boutin, Cecile Poulain, Florian P. Martin, Cynthia Fourgeux, Melanie Petrier, Manon Cannevet, Thomas Leclercq, Maeva Guillonneau, Tanguy Chaumette, Thomas Laurent, Christelle Harly, Emmanuel Scotet, Laurent Legentil, Vincent Ferrières, Stephanie
-
Transient synaptic CD61 pairing with CD103 increases the cytotoxicity of antigen-specific T cells Nat. Immunol. (IF 30.5) Pub Date : 2024-04-26
-
Apolipoprotein E controls Dectin-1-dependent development of monocyte-derived alveolar macrophages upon pulmonary β-glucan-induced inflammatory adaptation Nat. Immunol. (IF 30.5) Pub Date : 2024-04-26 H. Theobald, D. A. Bejarano, N. Katzmarski, J. Haub, J. Schulte-Schrepping, J. Yu, K. Bassler, A. L. Ament, C. Osei-Sarpong, F. Piattini, L. Vornholz, W. T’Jonck, A. H. Györfi, H. Hayer, X. Yu, S. Sheoran, A. Al Jawazneh, S. Chakarov, K. Haendler, G. D. Brown, D. L. Williams, L. Bosurgi, J. H. W. Distler, F. Ginhoux, J. Ruland, M. D. Beyer, M. Greter, C. C. Bain, A. I. Vazquez-Armendariz, M. Kopf,
-
A microbial iron fist to fight tumors Nat. Immunol. (IF 30.5) Pub Date : 2024-04-25 Samuel P. Nobs, Eran Elinav
-
A dietary commensal microbe enhances antitumor immunity by activating tumor macrophages to sequester iron Nat. Immunol. (IF 30.5) Pub Date : 2024-04-25 Garima Sharma, Amit Sharma, Inhae Kim, Dong Gon Cha, Somi Kim, Eun Seo Park, Jae Gyun Noh, Juhee Lee, Ja Hyeon Ku, Yoon Ha Choi, JungHo Kong, Haena Lee, Haeun Ko, Juhun Lee, Anna Notaro, Seol Hee Hong, Joon Haeng Rhee, Sang Geon Kim, Cristina De Castro, Antonio Molinaro, Kunyoo Shin, Sanguk Kim, Jong Kyoung Kim, Dipayan Rudra, Sin-Hyeog Im
-
JAK-STAT signaling maintains homeostasis in T cells and macrophages Nat. Immunol. (IF 30.5) Pub Date : 2024-04-24 Nikolaus Fortelny, Matthias Farlik, Victoria Fife, Anna-Dorothea Gorki, Caroline Lassnig, Barbara Maurer, Katrin Meissl, Marlies Dolezal, Laura Boccuni, Aarathy Ravi Sundar Jose Geetha, Mojoyinola Joanna Akagha, Anzhelika Karjalainen, Stephen Shoebridge, Asma Farhat, Ulrike Mann, Rohit Jain, Shweta Tikoo, Nina Zila, Wolfgang Esser-Skala, Thomas Krausgruber, Katarzyna Sitnik, Thomas Penz, Anastasiya
-
c-MAF and BLIMP-1 inhibit pathobiont-induced colitis by common and distinct immune pathways Nat. Immunol. (IF 30.5) Pub Date : 2024-04-19
-
Aged nasal epithelium is more prone to severe COVID-19 Nat. Immunol. (IF 30.5) Pub Date : 2024-04-19 Ivan Zanoni
-
Coordination of transcription factors and SWI–SNF complexes regulates chromatin priming in developing T cells Nat. Immunol. (IF 30.5) Pub Date : 2024-04-19 Jingwen Liao, Diana C. Hargreaves
-
Hepatocytes coordinate immune evasion in cancer via release of serum amyloid A proteins Nat. Immunol. (IF 30.5) Pub Date : 2024-04-19 Meredith L. Stone, Jesse Lee, Jae W. Lee, Heather Coho, Mito Tariveranmoshabad, Max M. Wattenberg, Hana Choi, Veronica M. Herrera, Yuqing Xue, Shaanti Choi-Bose, Sofia K. Zingone, Dhruv Patel, Kelly Markowitz, Devora Delman, Vinod P. Balachandran, Gregory L. Beatty
-
Fat matters for natural killer cell activity Nat. Immunol. (IF 30.5) Pub Date : 2024-04-18 Pamela Wong, Todd A. Fehniger
-
-
PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape Nat. Immunol. (IF 30.5) Pub Date : 2024-04-17 Noah Gamble, Alexandra Bradu, Jason A. Caldwell, Joshua McKeever, Olubusayo Bolonduro, Ebru Ermis, Caroline Kaiser, YeEun Kim, Benjamin Parks, Sandy Klemm, William J. Greenleaf, Gerald R. Crabtree, Andrew S. Koh
-
Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitis Nat. Immunol. (IF 30.5) Pub Date : 2024-04-12 Marisol Alvarez-Martinez, Luke S. Cox, Claire F. Pearson, William J. Branchett, Probir Chakravarty, Xuemei Wu, Hubert Slawinski, Alaa Al-Dibouni, Vasileios A. Samelis, Leona Gabryšová, Simon L. Priestnall, Alejandro Suárez-Bonnet, Anna Mikolajczak, James Briscoe, Fiona Powrie, Anne O’Garra
-
Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency Nat. Immunol. (IF 30.5) Pub Date : 2024-04-12 Hirotsugu Oda, Kalpana Manthiram, Pallavi Pimpale Chavan, Eva Rieser, Önay Veli, Öykü Kaya, Charles Rauch, Shuichiro Nakabo, Hye Sun Kuehn, Mariël Swart, Yanli Wang, Nisa Ilgim Çelik, Anne Molitor, Vahid Ziaee, Nasim Movahedi, Mohammad Shahrooei, Nima Parvaneh, Nasrin Alipour-olyei, Raphael Carapito, Qin Xu, Silvia Preite, David B. Beck, Jae Jin Chae, Michele Nehrebecky, Amanda K. Ombrello, Patrycja
-
The enduring neutrophil–stroma dance of multiple myeloma Nat. Immunol. (IF 30.5) Pub Date : 2024-04-10 Daniela Cerezo-Wallis, Iván Ballesteros
-
An IL-1β-driven neutrophil–stromal cell axis fosters a BAFF-rich protumor microenvironment in individuals with multiple myeloma Nat. Immunol. (IF 30.5) Pub Date : 2024-04-10 Madelon M. E. de Jong, Cathelijne Fokkema, Natalie Papazian, Ágnes Czeti, Marjolein K. Appelman, Michael Vermeulen, Teddie van Heusden, Remco M. Hoogenboezem, Gregory van Beek, Sabrin Tahri, Mathijs A. Sanders, Pieter C. van de Woestijne, Francesca Gay, Philippe Moreau, Maike Büttner-Herold, Heiko Bruns, Mark van Duin, Annemiek Broijl, Pieter Sonneveld, Tom Cupedo
-
Immune dysregulation in long COVID Nat. Immunol. (IF 30.5) Pub Date : 2024-04-08 Laura Ceglarek, Onur Boyman
-
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease Nat. Immunol. (IF 30.5) Pub Date : 2024-04-08 Felicity Liew, Claudia Efstathiou, Sara Fontanella, Matthew Richardson, Ruth Saunders, Dawid Swieboda, Jasmin K. Sidhu, Stephanie Ascough, Shona C. Moore, Noura Mohamed, Jose Nunag, Clara King, Olivia C. Leavy, Omer Elneima, Hamish J. C. McAuley, Aarti Shikotra, Amisha Singapuri, Marco Sereno, Victoria C. Harris, Linzy Houchen-Wolloff, Neil J. Greening, Nazir I. Lone, Matthew Thorpe, A. A. Roger Thompson
-
MEF2C regulates NK cell effector functions through control of lipid metabolism Nat. Immunol. (IF 30.5) Pub Date : 2024-04-08 Joey H. Li, Adalia Zhou, Cassidy D. Lee, Siya N. Shah, Jeong Hyun Ji, Vignesh Senthilkumar, Eddie T. Padilla, Andréa B. Ball, Qinyan Feng, Christian G. Bustillos, Luke Riggan, Alain Greige, Ajit S. Divakaruni, Fran Annese, Jessica Cooley-Coleman, Steven A. Skinner, Christopher W. Cowan, Timothy E. O’Sullivan
-
TCF1–LEF1 co-expression identifies a multipotent progenitor cell (TH2-MPP) across human allergic diseases Nat. Immunol. (IF 30.5) Pub Date : 2024-04-08 Radomir Kratchmarov, Sarah Djeddi, Garrett Dunlap, Wenqin He, Xiaojiong Jia, Caitlin M. Burk, Tessa Ryan, Alanna McGill, Jessica R. Allegretti, Raghu P. Kataru, Babak J. Mehrara, Erin M. Taylor, Shailesh Agarwal, Neil Bhattacharyya, Regan W. Bergmark, Alice Z. Maxfield, Stella Lee, Rachel Roditi, Daniel F. Dwyer, Joshua A. Boyce, Kathleen M. Buchheit, Tanya M. Laidlaw, Wayne G. Shreffler, Deepak A
-
Destressing microglia Nat. Immunol. (IF 30.5) Pub Date : 2024-04-02 Stephanie Houston
Na+/K+-ATPase (NKA) is a transmembrane protein that maintains neuronal resting membrane potential and has recently been shown to have a role in migraine, stroke and Parkinson’s disease. In Immunity, Huang et al. find that NKAα1 forms a complex with the P2X7R receptor, which regulates inflammasome activation in the microglia, and NKAα1 deficiency exacerbates neuronal excitability and anxiety-like behavior
-
Neutrophil subsets Nat. Immunol. (IF 30.5) Pub Date : 2024-04-02 Ioana Staicu
Tumor-associated neutrophils are thought to be immunosuppressive. In Cell, based on single-cell RNA sequencing of 17 cancer types (12 newly generated) from 143 patients, Wu et al. find that neutrophils exhibit diverse transcriptional profiles. Among the 10 states identified (S100A12+, HLA-DR+CD74+, VEGFA+SPP1+, TXNIP+, CXCL8+IL1B+, CXCR2+, IFIT1+ISG15+, MMP9+, NFKBIZ+HIF1A+ and ARG1+ neutrophils),
-
Facilitating broad antibody responses Nat. Immunol. (IF 30.5) Pub Date : 2024-04-02 Laurie A. Dempsey
A goal of immunization against highly mutable viruses is to elicit broadly neutralizing antibody responses. In Science, Sharma et al. report that the glycosphingolipid globotriaosylceramide (Gb3, also known as CD77) increases antibody affinity and diversity after immunization in a mouse model of influenza. Gb3 is highly expressed on germinal center B cells, where its abundance is regulated by α1,4-galactose
-
Prenatal and postnatal neuroimmune interactions in neurodevelopmental disorders Nat. Immunol. (IF 30.5) Pub Date : 2024-04-02 Eunha Kim, Jun R. Huh, Gloria B. Choi
The intricate relationship between immune dysregulation and neurodevelopmental disorders (NDDs) has been observed across the stages of both prenatal and postnatal development. In this Review, we provide a comprehensive overview of various maternal immune conditions, ranging from infections to chronic inflammatory conditions, that impact the neurodevelopment of the fetus during pregnancy. Furthermore
-
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity Nat. Immunol. (IF 30.5) Pub Date : 2024-04-01 Megat H. B. A. Hamid, Pablo F. Cespedes, Chen Jin, Ji-Li Chen, Uzi Gileadi, Elie Antoun, Zhu Liang, Fei Gao, Renuka Teague, Nikita Manoharan, David Maldonado-Perez, Nasullah Khalid-Alham, Lucia Cerundolo, Raul Ciaoca, Svenja S. Hester, Adán Pinto-Fernández, Simeon D. Draganov, Iolanda Vendrell, Guihai Liu, Xuan Yao, Audun Kvalvaag, Delaney C. C. Dominey-Foy, Charunya Nanayakkara, Nikolaos Kanellakis
Cancer remains one of the leading causes of mortality worldwide, leading to increased interest in utilizing immunotherapy strategies for better cancer treatments. In the past decade, CD103+ T cells have been associated with better clinical prognosis in patients with cancer. However, the specific immune mechanisms contributing toward CD103-mediated protective immunity remain unclear. Here, we show an
-
Thioredoxin is a metabolic rheostat controlling regulatory B cells Nat. Immunol. (IF 30.5) Pub Date : 2024-03-29 Hannah F. Bradford, Thomas C. R. McDonnell, Alexander Stewart, Andrew Skelton, Joseph Ng, Zara Baig, Franca Fraternali, Deborah Dunn-Walters, David A. Isenberg, Adnan R. Khan, Claudio Mauro, Claudia Mauri
Metabolic programming is important for B cell fate, but the bioenergetic requirement for regulatory B (Breg) cell differentiation and function is unknown. Here we show that Breg cell differentiation, unlike non-Breg cells, relies on mitochondrial electron transport and homeostatic levels of reactive oxygen species (ROS). Single-cell RNA sequencing analysis revealed that TXN, encoding the metabolic
-
Self-sustaining inflammatory cycle causes memory impairment in neuropsychiatric lupus Nat. Immunol. (IF 30.5) Pub Date : 2024-03-22
-
-
cGAS meets its demise in the nucleus Nat. Immunol. (IF 30.5) Pub Date : 2024-03-21 Calvin Jon A. Leonen, Hironori Funabiki
-
An immunophenotype-coupled transcriptomic atlas of human hematopoietic progenitors Nat. Immunol. (IF 30.5) Pub Date : 2024-03-21 Xuan Zhang, Baobao Song, Maximillian J. Carlino, Guangyuan Li, Kyle Ferchen, Mi Chen, Evrett N. Thompson, Bailee N. Kain, Dan Schnell, Kairavee Thakkar, Michal Kouril, Kang Jin, Stuart B. Hay, Sidharth Sen, David Bernardicius, Siyuan Ma, Sierra N. Bennett, Josh Croteau, Ornella Salvatori, Melvin H. Lye, Austin E. Gillen, Craig T. Jordan, Harinder Singh, Diane S. Krause, Nathan Salomonis, H. Leighton
-
Human lung cancer harbors spatially organized stem-immunity hubs associated with response to immunotherapy Nat. Immunol. (IF 30.5) Pub Date : 2024-03-19 Jonathan H. Chen, Linda T. Nieman, Maxwell Spurrell, Vjola Jorgji, Liad Elmelech, Peter Richieri, Katherine H. Xu, Roopa Madhu, Milan Parikh, Izabella Zamora, Arnav Mehta, Christopher S. Nabel, Samuel S. Freeman, Joshua D. Pirl, Chenyue Lu, Catherine B. Meador, Jaimie L. Barth, Mustafa Sakhi, Alexander L. Tang, Siranush Sarkizova, Colles Price, Nicolas F. Fernandez, George Emanuel, Jiang He, Katrina
-
International nomenclature guidelines for the IL-1 family of cytokines and receptors Nat. Immunol. (IF 30.5) Pub Date : 2024-03-18 Joseph M. Gaballa, Jesper Falkesgaard Højen, Dennis M. De Graaf, Jesus Amo-Aparicio, Carlo Marchetti, Giulio Cavalli, Alberto Dinarello, Suzhao Li, Michaele Francesco Corbisiero, Isak W. Tengesdal, Jasmina S. Redzic, Tania Azam, William S. Webber, Karl A. Pankratz, Makenna J. May, Fabio Cominelli, Elan Z. Eisenmesser, Soohyun Kim, Charles A. Dinarello, Diana Boraschi
Over the past 40 years, the IL-1 family has grown to include 22 members, with 11 cytokines and 11 receptors. After the initial description of the first IL-1 family members, confusion has grown about the nomenclature of IL-1 cytokines and receptors, which was last updated in 20101. This confusion arose from different names for the proteins identified by function. Several names for the same cytokine
-
A method for predicting drugs that can boost the efficacy of immune checkpoint blockade Nat. Immunol. (IF 30.5) Pub Date : 2024-03-18 Yun Xia, Xin Li, Nana Bie, Wen Pan, Ya-Ru Miao, Mei Yang, Yan Gao, Chuang Chen, Hanqing Liu, Lu Gan, An-Yuan Guo
-
Anaphylactic degranulation by mast cells requires the mobilization of inflammasome components Nat. Immunol. (IF 30.5) Pub Date : 2024-03-14 Andrea Mencarelli, Pradeep Bist, Hae Woong Choi, Hanif Javanmard Khameneh, Alessandra Mortellaro, Soman N. Abraham
-
Author Correction: The DExD/H-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila Nat. Immunol. (IF 30.5) Pub Date : 2024-03-15 Safia Deddouche, Nicolas Matt, Aidan Budd, Stefanie Mueller, Cordula Kemp, Delphine Galiana-Arnoux, Catherine Dostert, Christophe Antoniewski, Jules A. Hoffmann, Jean-Luc Imler
-
The power of memory T cells minus antibodies Nat. Immunol. (IF 30.5) Pub Date : 2024-03-15 Thi H. O. Nguyen, Katherine Kedzierska
-
Pas de deux of NLRP3 and ASC with CD63 on mast cell granules Nat. Immunol. (IF 30.5) Pub Date : 2024-03-14 J. Magarian Blander, Yuhua Shi
-
Antibody-independent protection against heterologous SARS-CoV-2 challenge conferred by prior infection or vaccination Nat. Immunol. (IF 30.5) Pub Date : 2024-03-14 Valeria Fumagalli, Micol Ravà, Davide Marotta, Pietro Di Lucia, Elisa B. Bono, Leonardo Giustini, Federica De Leo, Maura Casalgrandi, Emanuele Monteleone, Violette Mouro, Chiara Malpighi, Chiara Perucchini, Marta Grillo, Sara De Palma, Lorena Donnici, Silvia Marchese, Matteo Conti, Hiromi Muramatsu, Stanley Perlman, Norbert Pardi, Mirela Kuka, Raffaele De Francesco, Marco E. Bianchi, Luca G. Guidotti
-
The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis Nat. Immunol. (IF 30.5) Pub Date : 2024-03-07 Xin He, Xiantao Zhang, Bolin Wu, Jieyi Deng, Yongli Zhang, Airu Zhu, Yaochang Yuan, Yingtong Lin, Achun Chen, Jinzhu Feng, Xiumei Wang, Shijian Wu, Yingying Liu, Jie Liu, Yalin Wang, Rong Li, Chaofeng Liang, Quyu Yuan, Yu Liang, Qiannan Fang, Zhihui Xi, Wenjie Li, Liting Liang, Zhenglai Zhang, Hui Tang, Yi Peng, Changwen Ke, Xiancai Ma, Weibin Cai, Ting Pan, Bingfeng Liu, Kai Deng, Jun Chen, Jincun
-
Lupus autoantibodies initiate neuroinflammation sustained by continuous HMGB1:RAGE signaling and reversed by increased LAIR-1 expression Nat. Immunol. (IF 30.5) Pub Date : 2024-03-06 Kaitlin R. Carroll, Mark Mizrachi, Sean Simmons, Bahtiyar Toz, Czeslawa Kowal, Jeffrey Wingard, Nazila Tehrani, Aida Zarfeshani, Nina Kello, Lara El Khoury, Rachel Weissman-Tsukamoto, Joshua Z. Levin, Bruce T. Volpe, Betty Diamond
-
Learning from cancer mutations Nat. Immunol. (IF 30.5) Pub Date : 2024-03-01 Nicholas J. Bernard
T cell lymphomas acquire mutations that endow them with advantages to endure the immunosuppressive tumor microenvironment. Researchers have now found a way to turn the tables on cancer by using these mutations to develop more effective chimeric antigen receptor (CAR) T cell therapies. In a study published in Nature, the authors created a barcoded library of mutant genes from T cell malignancies and
-
Complement profile Nat. Immunol. (IF 30.5) Pub Date : 2024-03-01 Ioana Staicu
Severe COVID-19 has been associated with complement activation, hypercoagulation and vascular injury. In Science, Cervia-Hasler et al. report persistent complement-mediated immunopathology and thromboinflammation in long COVID as well. High-throughput proteomics on serum from 113 SARS-CoV-2-infected individuals (40 of which reported persisting symptoms at 6 months) at acute and 6 months after severe
-
Surface RNAs move neutrophils Nat. Immunol. (IF 30.5) Pub Date : 2024-03-01 Paula Jáuregui
RNAs have been detected on the outer surface of mammalian cells, including some with glycan modifications known as glycoRNAs; however, the biological function of these surface molecules is unclear. Research now published in Cell shows that on neutrophils these RNAs are required for efficient recruitment, adhesion and transendothelial migration at inflammatory sites in mice. Using extracellular RNase
-
What Jane Jacobs has taught me about neuroimmunology Nat. Immunol. (IF 30.5) Pub Date : 2024-03-01 Jennifer L. Gommerman
In acknowledgment of Women’s History Month, I have drawn upon timeless concepts from Jane Jacobs’ seminal 1961 book The Death and Life of Great American Cities1 to describe emerging ideas in neuroimmunology and how we may collectively move the field forward.
-
Opening the doors of opportunity Nat. Immunol. (IF 30.5) Pub Date : 2024-03-01 Noriko Isobe
Breakdown barriers that make you hesitate from challenging yourself, and jump into new fields that interest you.
-
Marching forward in neuroimmunology Nat. Immunol. (IF 30.5) Pub Date : 2024-03-01
As part of Women’s History Month, we are celebrating the contributions of women who stand at the crossroads of immunology and neurobiology.
-
Neuroimmunology, women scientists and dogma Nat. Immunol. (IF 30.5) Pub Date : 2024-03-01 Robyn S. Klein
Reflecting on the decision to become a neuroimmunologist, and the women mentors who taught me how to challenge dogma in all its forms.
-
Alterations of iron homeostasis as a potential druggable driver of long COVID Nat. Immunol. (IF 30.5) Pub Date : 2024-03-01 Oriana Marques, Martina U. Muckenthaler
-
Neuroimmunology, the field that welcomed me and made me want to stay Nat. Immunol. (IF 30.5) Pub Date : 2024-03-01 Irene Salinas
Entering a new scientific field is difficult and daunting. Here I relate my personal journey as a fish immunologist and how neuroimmunologists welcomed me with open arms (and brains), giving me the sense of belonging that we all need as scientists.