In this issue of Cancer Cell, Kumar et al. describe how CSF1R blockade induces not only an expected deprivation of tumor-associated macrophages, but also an accumulation of tumor-infiltrating polymorphonuclear mononuclear cells caused by Cxcl-1 released from cancer-associated fibroblasts.

中文翻译：

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CSF1R封锁会变成友善之火吗？

在本期《癌细胞》中，Kumar等人。描述了CSF1R阻断如何不仅诱导肿瘤相关巨噬细胞的预期剥夺，而且还诱导了由与癌症相关的成纤维细胞释放的Cxcl-1导致的肿瘤浸润多形核单核细胞的积累。