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Journal of Heterocyclic Chemistry
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Synthesis of a novel fused thieno‐pyrimidine with tetrazole analogs J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-03-13 Muthirevula Rajeswari, Begari Nagaraju, Venkata Rao Chunduri, Bhekumuzi Gumbi, Suresh Maddila
This current investigation represents the new series of fused thieno‐pyrimidine with synthesized tetrazole analogs (6a–j). Intermediates thieno‐[2,3‐d]‐pyrimidine were prepared by utilizing the Gewald method, and tetrazole (5a–j) was synthesized by [3 + 2] cycloaddition of azide and appropriate nitrile. All the prepared novel molecules were characterized and confirmed by 1HNMR, 13CNMR, LC‐MS, and FT‐IR
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Formal synthesis of 10‐Hydroxy‐6‐Aryldibenzo[b,g][1,8]Naphthyridin‐11(6H)‐ones from 2‐chloroquinolin‐3‐carbaldehydes and 3‐(Arylamino)cyclohexenones J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-03-13 Han‐Joo Lee, Joo‐Hyun Jeon, Jin‐Hee Kim, Hitesh B. Jalani, Jin‐Hyun Jeong
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One pot synthetic approach to 2‐methyl‐5‐phenyl‐7‐amino‐[1,3,4]‐thiadiazolo[3,2‐a]pyrimidine‐6‐carbonitrile derivatives with antifungal evaluation J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-03-12 Rimpi Saikia, Jumi Bharali, Sukanya Borthakur, Pabitra Kumar Kalita, Pradyut Sarma, Prakash Jyoti Saikia, Mintu Maan Dutta, Susanta Kumar Borthakur
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Ionic liquid‐supported copper‐catalyzed synthesis of 2H‐indazoles under microwave irradiation J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-03-11 Upala Dasmahapatra, Kaushik Chanda, Barnali Maiti
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Synthesis of hydantoins from N‐Boc protected amino acid derived amides using polymer‐supported PPh3/CBr4 as a reagent J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-03-09 Gordana Tasic, Nikola Mitrovic, Milena Simic, Mladen Koravovic, Predrag Jovanovic, Milos Petkovic, Milos Jovanovic, Branka Ivkovic, Vladimir Savic
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Recent developments in synthetic strategies and pharmacological outcomes of synthetic xanthine oxidase inhibitors: A comprehensive review J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-03-05 Gurinder Kaur, Rajiv Sharma, Ashu, Geetakshi Arora, Atamjit Singh, Preet Mohinder Singh Bedi, Kundan Singh Bora
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New energetic 1,2,4‐triazole‐nitrofuroxan hybrids J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-03-06 Alexander A. Larin, Ekaterina V. Dubasova, Ivan V. Ananyev, Konstantin A. Monogarov, Galina A. Gazieva, Leonid L. Fershtat
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Regioselective synthesis of (Z)‐5‐methylene‐containing morpholin‐2‐ones J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-02-26 Adriano F. Camargo, Genilson S. Pereira, Mateus Mittersteiner, Mário A. Marangoni, Paulo A. Moraes, Helio G. Bonacorso, Marcos A. P. Martins, Nilo Zanatta
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Synthesis of 1-(4-hydroxybutyl)-2-benzoyl indoles from 2-pyrrolidine benzaldehydes and α-bromoacetophenones in deep eutectic solvent J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-02-20 Guofang Jiang, Can Zhang, Xiaohong Xing, Jinbo Ouyang, Hong Yang, Zongbo Xie, Zhanggao Le
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Synthesis of benzo[b]pyran, 3,4 dihydropyrano[c]chromene and their new furan derivatives using Cu(II) complex of tetradentate Schiff‐base supported on silica as a nanocatalyst J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-02-21 Hashem Sharghi, Elahe Mashhadi, Seyyede Faeze Razavi, Mahdi Aberi
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Synthesis and biological evaluation of 3-hydroxypyrazoles as aquaporin 9 inhibitors J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-02-15 Subramani Selvi, Arun Kannan, John M. Jayaraj, Thangavel Selvi, Muthusamy Karthikeyan, Chidambaram Prahalathan, Natarajan Sampath, Kannupal Srinivasan
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Synthesis of tricyclic pyrazolopyrimidine arylidene ester derivatives and their cytotoxic and molecular docking evaluations J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-02-14 Tong Lu, Lifei Nie, Dan Tang, Khurshed Bozorov, Jiangyu Zhao, Haji Akber Aisa
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Novel oxadiazole functionalized pyridopyrimidine derivatives; their anticancer activity and molecular docking studies J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-02-13 Raghu Dasari, Srinivas Gali, Rajashekar Korra, Namratha Vaddiraju
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Synthesis of novel [1,2,3]triazolo[4′,5′:3,4]pyrrolo[1,2-a]thieno[2,3-d] pyrimidines: Potent EGFR targeting anti-breast cancer agents J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-01-29 Rajkumar Samala, Ranadheer Kumar M, Ashok Kumar Bapuram, Venkatarathnam Nasipireddy, Sirassu Narsimha
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Microwave-assisted synthesis of benzo[4,5]imidazo[1,2-a]pyrimidines and pyrano[4,3-b]pyrans catalyzed by L-glutamine functionalized magnetic nanoparticles in water:ethanol mixture J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-01-28 Aiborlang Thongni, Rishanlang Nongkhlaw, Chayan Pandya, Akella Sivaramakrishna, Paige M. Gannon, Werner Kaminsky
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Chemoselective direct amidation of fatty acids with furfurylamine without coupling reagents in reversed micellar microenvironment J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-01-26 Ayhan Yıldırım, Mehmet Suat Aksoy
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[3 + 2] Cycloaddition of nitrile oxides to dichloropropenes and 1,3-dichlorobut-2-ene: A regioselectivity issue J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-01-24 Alexandra N. Shilova, Nina S. Shatokhina, Evgeniy V. Kondrashov
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Application of the aza-Wittig reaction for efficient synthesis of diversely substituted benzo[f]Chromeno[2,3-d]pyrimidine and benzo[f]chromeno[2,3-d][1,2,4]triazolopyrimidine derivatives J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-01-23 Mohamed Hassan, Magda A. Barsy, Eman A. El Rady, Abdullah Sulaiman Al-Ayed, Mona Frempong, Kamal U. Sadek
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Synthesis and characterization of a highly fluorescent benzofuran dimer derived from estradiol J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-01-23 Gerardo I. Santiago-Sampedro, Martha C. Mayorquín-Torres, Andrés Aguilar-Granda, Martin A. Iglesias-Arteaga
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Dearomative [4 + 2] cycloaddition of 3-nitroindoles with ortho-amino Morita−Baylis−Hillman carbonates to forge indole-fused quinolines J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-01-16 Kai-Kai Wang, Yan-Li Li, Lan-Xin Li, Wei-Wei Yao, Ya-Fei Li, Wen-Fei Wang, Rongxiang Chen, Yi-Fan Hu, Aili Sun
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Novel pyrazole-biphenyl-carboxamides for SARS-CoV2 entry-level restriction and microbial infections J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-01-16 Shanmugha Samy, Milind Shrinivas Dangate, Manikandan Alagumuthu
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Manipulating sensitivities of planar oxadiazole-based high performing energetic materials J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-01-15 Ajay Kumar Chinnam, Jatinder Singh, Richard J. Staples, Jean'ne M. Shreeve
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Synthesis and antiviral activity of novel imidazo[2,1-b]thiazoles coupled with morpholine and thiomorpholines J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-01-10 Nagaraju Chirra, Varshitha Shanigarapu, Naga Pranathi Abburi, Ekaterina O. Sinegubova, Ravi Kumar Pedapati, Yana L. Esaulkova, Vladimir V. Zarubaev, Srinivas Kantevari
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Synthesis, antiproliferative activity, 3D-QSAR, and molecular docking studies of novel L-carvone-derived pyrimidine-urea compounds J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-01-09 Yupei Meng, Yunxue Zhang, Wengui Duan, Guishan Lin, Yucheng Cui, Baoyu Li
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Sc(OTf)3-catalyzed tandem (3+3)-annulation/lactonization of cyclopropanes with salicylaldehyde nitrones to access polycyclic 1,2-oxazines J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-01-07 Zhiping Liu, Jie Pang, Lijie Che, Liping Pang, Chunfang Gan, Jianguo Cui, Yanmin Huang
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Cu-catalyzed dehydrogenative C?O arylation for the synthesis of 6-methyl benzofuro[3,2-c] quinoline derivatives J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-01-07 Bhavik S. Makwana, Mayur I. Morja, Prakashsingh M. Chauhan, Kishor H. Chikhalia
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Visible light-mediated photocatalyzed synthesis of oxazole via intermolecular C?N and C?O bond formation J. Heterocycl. Chem. (IF 2.4) Pub Date : 2024-01-03 Mohd Zaheeruddin Beg, Shraddha Tivari, Akanksha Kashyap, Pravin K. Singh, Praveen P. Singh, Pankaj Nainwal, Vishal Srivastava
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Design, enantioselective synthesis, and antiviral activities against potato virus Y of axially chiral thiazine derivatives J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-12-26 Tingwei Shen, Jiamiao Jin, Jia Song, Hira Naz, Zhichao Jin, Yonggui Robin Chi, Xingxing Wu
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Catalyst-free one-pot synthesis of 2,4,5-tri- and 1,2,4,5-tetrasubstituted imidazoles J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-12-27 Priyanka V. Bandivadekar, Ganesh U. Chaturbhuj
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One-pot green synthesis, study of fluorescence properties, and biological activity of pyrano[3,2-c]chromenes derivatives via mesoporous materials MgO/SBA-15 J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-12-27 Ahmed Chelihi, Ridha Hassaine, Souad Nachat, Mohammed Benabdallah, Karima Bendahou, Mohammed Aissaoui, Merzouk Saidj, Ahmed Djafri, Leïla Boukenna, Abdelghani Bouchama, Noureddine Choukchou-Braham, Nadia Taibi
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Role of aurone ligands in microwave enhanced Mn (II) and Co (II) catalyzed dehydrogenative coupling reaction: An efficient ligand for the synthesis of quinoline, pyridine, and pyrrole J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-12-23 Shachi Mishra, Chandan Prakash, Bhartendu Pati Tripathi
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Amine and nitramine functionalization of imidazole-triazine and triazole-triazine skeletons: Exploring for potential multipurpose energetic materials J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-12-19 Abhishek Kumar Yadav, Manojkumar Jujam, Vikas D. Ghule, Srinivas Dharavath
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Research progress of triazole derivatives in the discovery of agricultural chemicals J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-12-18 Hongyi Song, Sheng Wang, Qingfeng Cai, Jixiang Chen
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Regiospecific synthesis of novel spiro-pyrimidobarbiturates with promising antibacterial activities J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-12-18 Bahgat R. M. Hussein, Amr H. Moustafa
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4-substituted push-pull quinazoline chromophores with extended π-conjugated linker J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-12-13 Thibault Bonnaud, Mathieu Scaviner, Françoise Robin-le Guen, Sylvain Achelle
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An eco-friendly, sustainable, and greener approach to the synthesis of Dihydroquinazolin-4(1H)-ones using a deep eutectic solvent J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-12-10 Gobind Kumar, Pule Seboletswe, Neha Manhas, Parvesh Singh, Gaurav Bhargava, Jaspreet Kaur Rajput, Rupesh Kumar
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Synthesis of potential impurities of cloxacillin sodium drug substance J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-12-04 Gollapalli Venkateswara Rao, Santhosh R. Pindi, Bollikolla Hari Babu, Bala Murali Krishna Khandapu
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Synthesis of nitro-containing isoquinoline-1,3-diones with tert-butyl nitrite J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-12-03 Hongsheng Ma, Tongyan Yu, Siliang You, Ming-Zhi Zhang, Chao Deng
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Hantzsch-like synthesis of isoquinolino[2,1-a]quinoline-12-carbonitrile incorporating aryl or heteroaryl moieties at C-13 J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-12-03 Mohamed A. Mohamed Teleb, Hamdi M. Hassaneen, Ismail A. Abdelhamid, Fatma M. Saleh
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New thieno[2,3-d]pyrimidine derivatives as EGFRWT and EGFRT790M inhibitors: Design, synthesis, antiproliferative activities, docking studies, ADMET, toxicity, MD simulation studies J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-11-27 Eman A. Sobh, Mohammed A. Dahab, Eslam B. Elkaeed, Bshra A. Alsfouk, Ibrahim M. Ibrahim, Ahmed M. Metwaly, Ibrahim H. Eissa
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Glycerol-1,2-carbonate: A mild reagent for the N-glycerylation of pyrazolecarboxylates J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-11-27 Inesa Zagorskytė, Aurimas Bieliauskas, Milda Pukalskienė, Patrick Rollin, Eglė Arbačiauskienė, Algirdas Šačkus
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Arylhydrazine salt-selenium: A novel and efficient reagent system for arylselenenylation of unprotected uracil and its derivatives J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-11-27 Yi Wu, Qi-Yun Peng, Yan-Ling He, Xiao-He Zheng, Yan-Qin Chen, Hai-Bo Wang, Bing Wang, Jun Xie, Lei Tang, Cong Wang
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Indeno[1,2-b]pyridin-5-one derivatives containing azo groups and their hydrazonal precursors: Synthesis, antimicrobial profile, DNA gyrase binding affinity, and molecular docking J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-11-21 Refaie M. Kassab, Zeinab A. Muhammad, Sami A. Al-Hussain, Magdi E. A. Zaki, Mona H. Ibrahim, Amani M. R. Alsaedi, Thoraya A. Farghaly
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From 2011 to 2022: The development of pyrazole derivatives through the α,β-unsaturated carbonyl compounds J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-11-22 Shubham Sharma, Virender Singh, Vaishali, Rakesh Kumar, Rahul Jamra, Naveen Banyal, Jyoti
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Cover Image J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-11-15 Aravinda Babu, K. Sunil, Ayyiliath Meleveetil Sajith, Nibin Joy Muthipeedika, Sougata Santra, Grigory V. Zyryanov
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Synthesis and characterizations of some new selenolo[2,3-b]quinoxaline derivatives J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-11-15 Fatma K. Abdelwadoud, Gehad S. Gomaa, Ahmed A. Geies
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Cobalt perchlorate hexahydrate catalyzed one-pot synthesis of dihydropyrimidin-ones/-thiones through sonochemistry and its mechanistic study using density functional theory calculations J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-11-13 Ramesh Ambatwar, Sumit Kumar, Dhairiya Agarwal, Lokesh Chandrakar, Gopal L. Khatik
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Organocatalyzed cycloaddition reactions of azomethine imines—A lookback J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-11-08 Bastin K. Jose, Athulya Simon, Niranjana Subrahmanian, P. Adhwithi, Sindhu Mathai
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An operationally simple, one-pot, convenient synthesis, and in vitro anti-inflammatory activity of some new spirotriazolotriazine derivatives J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-11-08 Ahmed M. El-Saghier, Souhaila S. Enaili, Aly Abdou, Amany M. Hamed, Asmaa M. Kadry
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Regioselective synthesis of new imidazo[4,5-e][1,3]thiazino[2,3-c][1,2,4]triazines via reaction of imidazo[4,5-e][1,2,4]triazinethiones with ethyl phenylpropiolate J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-11-07 Dmitry B. Vinogradov, Alexei N. Izmest'ev, Angelina N. Kravchenko, Natalya G. Kolotyrkina, Galina A. Gazieva
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A new synthesis of 3′-deoxy-3′-fluoroadenosine, a key intermediate of cyclic dinucleotide J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-11-05 Yayun Qiu, Zixing Li, Fangmin Ning, Dandan Tang, Huansheng Chen
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Green synthesis and biological activity investigation of new derivatives of spiroisatins J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-11-03 Sajjad Ahmadi, Zinatossadat Hossaini, Daryoush Zareyee, Somayeh Soleimani Amiri, Sattar Arshadi
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Research progress of oxazole derivatives in the discovery of agricultural chemicals J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-11-03 Sheng Wang, Hongyi Song, Qingfeng Cai, Jixiang Chen
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Synthesis and characterization of novel polyurethanes, polypyridazine, and polyamide based on s-1,2,4,5-tetrazine J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-11-03 Abdelwahed R. Sayed, Jeffrey S. Wiggins
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Recent advance: Sulfur ylides in organic synthesis J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-10-26 Manoj Kumar, Ifrah Sadaf, Jyotsna Pamidighantam, Anamika, Sonu Kumar
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Advances in Biginelli reaction: A comprehensive review J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-10-23 Aravind Chandravarkar, Thaipparambil Aneeja, Gopinathan Anilkumar
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Synthesis of new 2-pyridinone and thiazole derivatives containing coumarin moiety J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-10-22 Reem A. K. Al-Harbi, Heba A. Emam, Samir Y. Abbas
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The Ritter reaction of N-(hydroxymethyl)saccharin with nitriles J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-10-20 Marllon Nascimento de Oliveira, Marcio C. S. de Mattos
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N?N bridged pyrazoles from nitrogen-centered radicals: A comparative study of spin densities, molecular structures, and reactivities J. Heterocycl. Chem. (IF 2.4) Pub Date : 2023-10-20 Zhiwei Zeng, Wei Huang, Yuji Liu, Yongxing Tang