-
CO2 facilitated upcycling of polyolefin plastics to aromatics at low temperature Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-03-15 Yi Ding, Shuchi Zhang, Cheng Liu, Yu Shao, Xiulian Pan, Xinhe Bao
Plastics are one of the most produced synthetic materials and the largest commodities, used in numerous sectors of human life. To upcycle waste plastics into value-added chemicals is a global challenge. Despite significant progress in pyrolysis and hydrocracking which mainly leads to formation of pyrolysis oil, catalytic upcycling to value-added aromatics including benzene, toluene and xylene (BTX)
-
Electron spin resonance analysis of photoenzymatic catalysis Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-03-15 Lu Yu, Changlin Tian
This Perspective highlights recent research progress and prospects in elucidating the catalytic mechanism of photoenzymes using ESR (electron spin resonance) spectroscopy, which is emerging as a unique and crucial method for identifying radical intermediates, illustrating electron transfer events and the underlying mechanisms of photoenzymatic catalysis.
-
Phanerozoic Coevolution of O2-CO2 and Ocean Habitability Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-03-14 Zunli Lu, Rosalind E M Rickaby, Jonathan L Payne, Ashley N Prow
This perspective reviews how atmospheric compositions, animals and marine algae evolved together to determine global ocean habitability during the past 500 million years.
-
Ordered mesoporous nanofibers mimicking vascular bundles for lithium metal batteries Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-03-12 Xiaohang Zhu, Mengmeng Liu, Fanxing Bu, Xin-Yang Yue, Xiang Fei, Yong-Ning Zhou, Anqi Ju, Jianping Yang, Pengpeng Qiu, Qi Xiao, Chao Lin, Wan Jiang, Lianjun Wang, Xiaopeng Li, Wei Luo
Hierarchical self-assembly with long-range order above centimeters widely exists in nature. Mimicking similar structures to promote reaction kinetics of electrochemical energy devices is of immense interest, yet remains challenging. Here, we report a bottom-up self-assembly approach to constructing ordered mesoporous nanofibers with a structure resembling vascular bundles via electrospinning. The synthesis
-
Water and other volatiles on Mars Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-03-11 Sen Hu, Yubing Gao, Zhan Zhou, Liang Gao, Yangting Lin
This perspective reviews the recent advances in martian water and other volatiles and addresses the associated scientific questions for future martian exploration missions.
-
The super-cycle of the global land-monsoon system Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-03-09 Yongyun Hu
The global land-monsoon system demonstrates super-cycles in both area and precipitation intensity in the Phanerozoic. The cyclicity of the global land-monsoon closely follows the supercontinent cycle, indicating the governance of continental configurations on the global land-monsoon over tectonic timescales.
-
Universal origin of glassy relaxation as recognized by configuration pattern-matching Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-03-09 Hai-Bin Yu, Liang Gao, Jia-Qi Gao, Konrad Samwer
Relaxation processes are crucial in understanding the structural rearrangements of liquids and amorphous materials. However, the overarching principle that governs these processes across vastly different materials remains an open question. Substantial analysis has been carried out based on the motions of individual particles. Here, alternatively, we propose viewing the global configuration as a single
-
Highly efficient nitrogen fixation over S-scheme heterojunction photocatalysts with enhanced active hydrogen supply Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-03-09 Tong Bao, Yamin Xi, Chaoqi Zhang, Peiyang Du, Yitong Xiang, Jiaxin Li, Ling Yuan, Chengzhong Yu, Chao Liu
Photocatalytic N2 fixation is a promising strategy for ammonia (NH3) synthesis, however suffering from relatively low ammonia yield due to the difficulty in the design of photocatalysts with both high charge transfer efficiency and desirable N2 adsorption/activation capability. Herein, a S-scheme CoSx/ZnS heterojunction with dual active sites is designed as an efficient N2 fixation photocatalyst. The
-
Band-like transport in solution-processed perylene diimide dianion films with high hall mobility Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-03-08 Yanhua Jia, Qinglin Jiang, Hanlin Gan, Bohan Wang, Xiandong He, Jiadong Zhou, Zetong Ma, Jiang Zhang, Yuguang Ma
It is crucial to prepare high-mobility organic polycrystalline film through solution processing. However, the delocalized carrier transport of polycrystalline films in organic semiconductors has rarely been investigated through Hall effect measurement. This study presents a strategy for building strong intermolecular interactions to fabricate solution-crystallized p-type perylene diimide (PDI) dianion
-
A heat transfer model for liquid film boiling on micro-structured surfaces Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-03-08 Pengkun Li, Qifan Zou, Xiuliang Liu, Ronggui Yang
High heat transfer coefficient (HTC) and critical heat flux (CHF) are achieved in liquid film boiling by coupling vibrant vapor bubbles with a capillary liquid film, which has thus received increased interest for thermal management of high-power electronics. Although quite some experimental progresses have been made, there lacks a high-fidelity heat transfer model for liquid film boiling. This work
-
Dynamic neural networks: advantages and challenges Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-03-06 Gao Huang
This perspective article delves into the transformative realm of dynamic neural networks, which is reshaping AI with adaptable structures and improved efficiency, bridging the gap between artificial and human intelligence.
-
Engineering surface framework TiO6 single sites for unprecedented deep oxidative desulfurization Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-03-05 Shen Yu, Zhan Liu, Jia-Min Lyu, Chun-Mu Guo, Xiao- Yu Yang, Peng Jiang, Yi-Long Wang, Zhi-Yi Hu, Ming-Hui Sun, Yu Li, Li-Hua Chen, Bao-Lian Su
Catalytic oxidative desulfurization (ODS) using titanium silicate catalysts emerges as an efficient technique for the complete removal of organosulfur compounds from automotive fuels. However, the precise control of highly accessible and stable framework Ti active sites remains highly challenging. Here we reveal for the first time by the density functional theory calculations that framework hexa-coordinated
-
Energy Spectrum Theory of Incommensurate Systems Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-03-04 Zhe He, Xin-Yu Guo, Zhen Ma, Jin-Hua Gao
Due to the lack of the translational symmetry, calculating the energy spectrum of an incommensurate system has always been a theoretical challenge. Here, we propose a natural approach to generalize the energy band theory to the incommensurate systems without reliance on the commensurate approximation, thus providing a comprehensive energy spectrum theory of the incommensurate systems. Except for a
-
A chaotic spiking backpropagation approach to brain learning Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-03-02 Guanrong Chen
A highlight of the chaotic spiking backpropagation (CSBP) method, which is a powerful tool for directly training spiking neural networks and helps to understand the learning mechanisms of human brain.
-
Imitating and exploring human brain's resting and task-performing states via resembling brain computing: scaling and architecture Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-03-02 Wenlian Lu, Longbin Zeng, Jiexiang Wang, Shitong Xiang, Yang Qi, Qibao Zheng, Ningsheng Xu, Jianfeng Feng
The computational human brain model with voxel-wise assimilation method is established based on individual structural and functional imaging data. We found that the more resembling the brain was in both scale and architecture, the more similarity was found between the assimilated model and the biological brain both in resting states and during tasks by quantitative metrics. The hypothesis that resting
-
Beyond network centrality: Individual-level behavioral traits for predicting information superspreaders in social media Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-03-02 Fang Zhou, Linyuan Lü, Jianguo Liu, Manuel Sebastian Mariani
Understanding the heterogeneous role of individuals in large-scale information spreading is essential to manage online behavior as well as its potential offline consequences. To this end, most existing studies from diverse research domains focus on the disproportionate role played by highly-connected “hub” individuals. However, we demonstrate here that information superspreaders in online social media
-
Control of defensive behavior by the nucleus of Darkschewitsch GABAergic neurons Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-03-01 Huiying Zhao, Jinrong Liu, Yujin Shao, Xiang Feng, Binhan Zhao, Li Sun, Yijun Liu, Linghui Zeng, Xiao-ming Li, Hongbin Yang, Shumin Duan, Yan-qin Yu
The nucleus of Darkschewitsch (ND), mainly composed of GABAergic neurons, is widely recognized as a component of the eye-movement controlling system. However, the functional contribution of ND GABAergic neurons (NDGABA) in animal behavior is largely unknown. Here, we show that NDGABA neurons were selectively activated by different types of fear stimuli, such as predator odor and foot-shock. Optogenetic
-
Typhoon- and pollution-driven enhancement of reactive bromine in the mid-latitude marine boundary layer Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-29 Shanshan Wang, Qinyi Li, Ruifeng Zhang, Anoop Sharad Mahajan, Swaleha Inamdar, Nuria Benavent, Sanbao Zhang, Ruibin Xue, Jian Zhu, Chenji Jin, Yan Zhang, Xiao Fu, Alba Badia, Rafael P Fernandez, Carlos A Cuevas, Tao Wang, Bin Zhou, Alfonso Saiz-Lopez
Tropospheric reactive bromine is important for atmospheric chemistry, regional air pollution, and global climate. Previous studies have reported measurements of atmospheric reactive bromine species in different environments, and proposed their main sources, e.g. sea-salt aerosol (SSA), oceanic biogenic activity, polar snow/ice, and volcanoes. Typhoons and other strong cyclonic activities (e.g. hurricanes)
-
Magnetic manipulation of the reactivity of singlet oxygen: from test tubes to living cells Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-28 Zi-Shu Yang, Song Gao, Jun-Long Zhang
Although magnetism undoubtedly influences life on Earth, the science behind biological magnetic sensing is largely a mystery, and it has proved challenging, especially in the life sciences, to harness the interactions of magnetic fields (MFs) with matter to achieve specific ends. Using the well-established radical pair (RP) mechanism, we here demonstrate a bottom-up strategy for the exploitation of
-
Virtual brain twins: from basic neuroscience to clinical use Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-27 Huifang E Wang, Paul Triebkorn, Martin Breyton, Borana Dollomaja, Jean-Didier Lemarechal, Spase Petkoski, Pierpaolo Sorrentino, Damien Depannemaecker, Meysam Hashemi, Viktor K Jirsa
Virtual brain twins are personalized, generative and adaptive brain models based on data from an individual’s brain for scientific and clinical use. After description of key elements of virtual brain twins, we present the standard model for personalized whole-brain network models. The personalization is accomplished using a subject’s brain imaging data by three means: 1) assemble cortical and subcortical
-
Biomaterial design for regenerating aged bone: materiobiological advances and paradigmatic shifts Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-27 Kai Dai, Zhen Geng, Wenchao Zhang, Xue Wei, Jing Wang, Guangjun Nie, Changsheng Liu
China's aging demographic poses a challenge for treating prevalent bone diseases impacting life quality. As bone regeneration capacity diminishes with age due to cellular dysfunction and inflammation, advanced biomaterials-based approaches offer hope for aged bone regeneration. This review synthesizes materiobiology principles, focusing on biomaterials that target specific biological functions to restore
-
Wafer-level heterogeneous integration of electrochemical devices and semiconductors for a monolithic chip Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-27 Sixing Xu, Fan Xia, Zhangshanhao Li, Minghao Xu, Bingmeng Hu, Haizhao Feng, Xiaohong Wang
Micro-scale electrochemical devices, despite their wide applications and unique potential to achieve ‘More than Moore's law’, face significant limitations in constructing functional chips due to their inability to integrate with semiconductors. In this study, we propose an electrochemical gating effect and material work function matching criteria, and thus establish the first heterogeneous integration
-
Advancing brain-inspired computing with Hybrid Neural networks Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-27 Faqiang Liu, Hao Zheng, Songchen Ma, Weihao Zhang, Xue Liu, Yansong Chua, Luping Shi, Rong Zhao
Brain-inspired computing, drawing inspiration from the fundamental structure and information-processing mechanisms of the human brain, has gained significant momentum in recent years. It has emerged as a research paradigm centered around brain-computer dual-driven and multi-network integration. One noteworthy instance of this paradigm is the Hybrid Neural Network (HNN), which integrates computer-science-oriented
-
Ultra-low frequency magnetic energy focusing for highly effective wireless powering of deep-tissue implantable electronic devices Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-27 Yuanyuan Li, Zhipeng Chen, Yuxin Liu, Zijian Liu, Tong Wu, Yuanxi Zhang, Lelun Peng, Xinshuo Huang, Shuang Huang, Xudong Lin, Xi Xie, Lelun Jiang
The limited lifespan of batteries is a challenge in the application of implantable electronic devices. Existing wireless power technologies such as ultrasound, near-infrared light, and magnetic field cannot charge devices implanted in deep tissues, resulting in energy attenuation through tissues and thermal generation. Herein, an ultra-low frequency magnetic energy focusing (ULFMEF) methodology was
-
Experimental demonstration of topological bounds in quantum metrology Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-27 Min Yu, Xiangbei Li, Yaoming Chu, Bruno Mera, F Nur Ünal, Pengcheng Yang, Yu Liu, Nathan Goldman, Jianming Cai
Quantum metrology is deeply connected to quantum geometry, through the fundamental notion of quantum Fisher information. Inspired by advances in topological matter, it was recently suggested that the Berry curvature and Chern numbers of band structures can dictate strict lower bounds on metrological properties, hence establishing a strong connection between topology and quantum metrology. In this work
-
The current status and future development of high-temperature conventional superconductivity Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-25 M I Eremets
This survey highlights key advancements in high-temperature superconductivity in hydrogen-rich materials, emphasising the robust evidence and reproducibility of superconductivity under challenging experimental conditions of megabar pressures. In the near future, achieving room-temperature superconductivity is highly probable, and the field is expected to transition towards near-ambient-pressure superconductivity
-
Three-stage niobium mineralization at Bayan Obo, China Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-21 Yan Yu, Yang Li, Yu Liu, Xiao-Xiao Ling, Li-Guang Wu, Li Yang, Lan Yang, Bo Yang, Yong-Gang Zhao, Xian-Hua Li
The Chinese Bayan Obo deposit is a world-class rare earth element (REE) deposit with considerable niobium (Nb) and iron (Fe) resources. A complete genetic understanding on all metals is fundamental for establishing genetic models at Bayan Obo. With extensive research being focused on REE enrichment, the timing and controls of Nb enrichment remain unresolved at Bayan Obo, which mainly due to the challenges
-
Surface heterojunction based on n-type low dimensional perovskite film for highly efficient perovskite tandem solar cells Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-16 Xianyuan Jiang, Qilin Zhou, Yue Lu, Hao Liang, Wenzhuo Li, Qi Wei, Mengling Pan, Xin Wen, Xingzhi Wang, Wei Zhou, Danni Yu, Hao Wang, Ni Yin, Hao Chen, Hansheng Li, Ting Pan, Mingyu Ma, Gaoqi Liu, Wenjia Zhou, Zhenhuang Su, Qi Chen, Fengjia Fan, Fan Zheng, Xingyu Gao, Qingqing Ji, Zhijun Ning
Enhancing the quality of junctions is crucial for optimizing carrier extraction and suppressing recombination in semiconductor devices. In recent years, metal halide perovskite is emerging as the most promising next-generation materials for optoelectronic devices. However, the construction of high-quality perovskite junctions, as well as characterization and understanding of their carrier polarity
-
Micelles directed self-assembly to single-crystal-like mesoporous stoichiometric oxides for high-performance lithium storage Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-07 Yanhua Wan, Changyao Wang, Xingmiao Zhang, Yang Yin, Mengmeng Liu, Bing Ma, Linlin Duan, Yuzhu Ma, Wei Zhang, Changlin Zheng, Dongliang Chao, Fei Wang, Yongyao Xia, Wei Li
Due to the uncontrollable assembly and crystallization process, the synthesis of mesoporous metal oxide single crystals remains a formidable challenge. Herein, we report the synthesis of single-crystal-like mesoporous Li2TiSiO5 by using soft micelles as templates. The key lies in the atomic-scale self-assembly and step-crystallization processes, which ensure the formation of single-crystal-like mesoporous
-
Bridging digital and electromagnetic realms for enhanced wireless communication: current space Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-07 Qammer H Abbasi
Recently, Tie Jun Cui and team members introduced innovativemacroscopic and statistical models for digital coding metasurfaces, bridging the digital and electromagnetic realms and quantifying information loss for enhanced wireless communication system design. This is a highlight of it.
-
Displacement-pressure biparametrically regulated softness sensory system for intraocular pressure monitoring Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-07 Yu Cheng, Yifei Zhan, Fangyi Guan, Junli Shi, Jingxiao Wang, Yi Sun, Muhammad Zubair, Cunjiang Yu, Chuan Fei Guo
High intraocular pressure (IOP) is one of the high-risk pathogenic factors of glaucoma. Existing methods of IOP measurement are based on the direct interaction with the cornea. Commercial ophthalmic tonometers based on snapshot measurements are expensive, bucky, and their operation requires trained personnel; theranostic contact-lenses are easy to operate, but they may block vision and cause infection
-
Bias distribution and regulation in photoelectrochemical overall water-splitting cells Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-07 Kun Dang, Siqin Liu, Lei Wu, Daojian Tang, Jing Xue, Jiaming Wang, Hongwei Ji, Chuncheng Chen, Yuchao Zhang, Jincai Zhao
The water oxidation half-reaction at anodes is always considered the rate-limiting step of overall water splitting (OWS), but the actual bias distribution between photoanodes and cathodes of photoelectrochemical (PEC) OWS cells has not been investigated systematically. In this work, we find that for PEC cells consisting of photoanodes (nickel-modified n-Si [Ni/n-Si] and α-Fe2O3) with low photovoltage
-
Discontinuous phase diagram of amorphous carbons Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-07 YinBo Zhu, ZhouYu Fang, ZhongTing Zhang, HengAn Wu
The short-range order and medium-range order of amorphous carbons demonstrated in experiments allow us to rethink whether they exist intrinsic properties hidden by atomic disordering. We here presented six representative phases of amorphous carbons (0.1-3.4 g/cm3), namely, disordered graphene network (DGN), high-density amorphous carbon (HDAC), amorphous diaphite (a-DG), amorphous diamond (a-D), paracrystalline
-
Unveiling the next generation of MRI contrast agents: current insights and perspectives on ferumoxytol-enhanced MRI Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-06 Guangxiang Si, Yue Du, Peng Tang, Gao Ma, Zhaochen Jia, Xiaoyue Zhou, Dan Mu, Yan Shen, Yi Lu, Yu Mao, Chuan Chen, Yan Li, Ning Gu
Contrast-enhanced magnetic resonance imaging (CE-MRI) is a pivotal tool for global disease diagnosis and management. Since its clinical availability in 2009, the off-label use of ferumoxytol for ferumoxytol-enhanced MRI (FE-MRI) has significantly reshaped CE-MRI practices. Unlike MRI that's enhanced by gadolinium-based contrast agents, FE-MRI offers advantages such as reduced contrast agent dosage
-
Sub-10 nm sized Au@AuxIr1−x metal-core/alloy-shell nanoparticles as highly durable catalysts for acidic water splitting Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-06 Huimin Wang, Zhe-ning Chen, Yuanyuan Wang, Dongshuang Wu, Minna Cao, Fanfei Sun, Rong Cao
The absence of efficient and durable catalysts for oxygen evolution reaction (OER) is the main obstacle to hydrogen production through water splitting in the acidic electrolyte. Here, we report a controllable synthesis method of surface IrOx with changing Au/Ir compositions by construing a range of sub-10 nm sized core-shell nanocatalysts composed of Au core and AuxIr1−x alloy shell. Particularly,
-
Uncovering key salt-tolerant regulators through a combined eQTL and GWAS analysis using the super pan-genome in rice Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-06 Hua Wei, Xianmeng Wang, Zhipeng Zhang, Longbo Yang, Qianqian Zhang, Yilin Li, Huiying He, Dandan Chen, Bin Zhang, Chongke Zheng, Yue Leng, Xinglan Cao, Yan Cui, Chuanlin Shi, Yifan Liu, Yang Lv, Jie Ma, Wenchuang He, Xiangpei Liu, Qiang Xu, Qiaoling Yuan, Xiaoman Yu, Tianyi Wang, Hongge Qian, Xiaoxia Li, Bintao Zhang, Hong Zhang, Wu Chen, Mingliang Guo, Xiaofan Dai, Yuexing Wang, Xiaoming Zheng, Longbiao
For sessile plants, gene expression plays a pivotal role in responding to salinity stress by activating or suppressing specific genes. However, our knowledge of genetic variations governing gene expression in response to salt stress remains limited in natural germplasm. Through transcriptome analysis of the Global MiniCore Rice Collection consisting of a panel of 202 accessions, we identified 22 345
-
The dynamic surface evolution of halide perovskites induced by external energy stimulation Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-03 Feiyu Cheng, Pengdong Wang, Chenzhe Xu, Qingliang Liao, Suicai Zhang, Haochun Sun, Wenqiang Fan, Guodong Liu, Zhiyun Li, Yaping Kong, Li Wang, Fangsen Li, Zhuo Kang, Yue Zhang
Tracking the dynamic surface evolution of metal halide perovskite is crucial for understanding the corresponding fundamental principles of photoelectric properties and intrinsic instability. However, due to the volatility elements and soft lattice nature of perovskites, several important dynamic behaviors remain unclear. Here, an ultra-high vacuum (UHV) interconnection system integrated by surface-sensitive
-
Introducing urea into the tirapazamine derivatives to enhance anti-cancer therapy Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-02 Yajun Xu, Jianlin Lv, Chaoying Kong, Ya Liu, Kun Wang, Zhaohui Tang, Xuesi Chen
Tirapazamine (TPZ) has been approved for multiple clinical trials relying on its excellent anti-cancer potential. However, as a typical hypoxia-activated prodrugs (HAPs), TPZ did not exhibit survival advantages in phase III clinical trials when used in a combination therapy due to the insufficient hypoxia levels in patient's tumors. In this study, to improve the therapeutic effects of TPZ, we first
-
Steric hindrance modulation of hexaazatribenzanthraquinone isomers for high capacity and wide-temperature-range aqueous proton battery Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-02-02 Mingsheng Yang, Yuxin Hao, Bei Wang, Yan Wang, Liping Zheng, Rui Li, Huige Ma, Xinyu Wang, Xiaoming Jing, Hongwei Li, Mengxiao Li, Zhihui Wang, Yujie Dai, Guangcun Shan, Mingjun Hu, Jun Luo, Jun Yang
Organic materials with rich active sites are good candidates of high-capacity anodes in aqueous batteries, but commonly low utilization of active sites limits their capacity. Herein, two isomers, symmetric hexaazatribenzanthraquinone (s-HATBAQ) and asymmetric one (a-HATBAQ), with rich active sites have been synthesized in a controllable manner. It is the first time to reveal that sulfuric acid catalyst
-
Brain-inspired Chaotic Spiking Backpropagation Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-30 Zijian Wang, Peng Tao, Luonan Chen
Spiking neural networks (SNNs) have superior energy efficiency due to their spiking signal transmission, which mimics biological nervous systems, but are difficult to train effectively. Although surrogate gradient-based methods offer a workable solution, trained SNNs frequently fall into local minima because they are still primarily based on gradient dynamics. Inspired by the chaotic dynamics in animal
-
Bacterial responsive programmed self-activating antibacterial hydrogel to remodel regeneration microenvironment for infected wound healing Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-29 Yutong Yang, Jiaxin Wang, Shengfei Huang, Meng Li, Jueying Chen, Dandan Pei, Zhen Tang, Baolin Guo
There is still an urgent need to develop hydrogels with intelligent antibacterial ability to achieve on-demand treatment of infected wounds and accelerate wound healing by improving the regeneration microenvironment. We proposed a strategy of hydrogel wound dressing with bacterial responsive self-activating antibacterial property and multiple nanozyme activities to remodel regeneration microenvironment
-
N6-methyladenosine facilitates mitochondrial fusion of colorectal cancer cells via induction of GSH synthesis and stabilization of OPA1 mRNA Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-29 Jiawang Zhou, Haisheng Zhang, Ke Zhong, Lijun Tao, Yu Lin, Guoyou Xie, Yonghuang Tan, You Wu, Yunqing Lu, Zhuojia Chen, Jiexin Li, Xin Deng, Qin Peng, Zigang Li, Hongsheng Wang
Mitochondria undergo fission and fusion is critical for cell survival and cancer development, while the regulatory factors for mitochondrial dynamic remain elusive. Herein we found that RNA m6A accelerated mitochondria fusion of colorectal cancer cells. Metabolomics analysis and function studies indicated that m6A triggered the generation of glutathione via the upregulation of RRM2B, a p53-inducible
-
Ultrafast micro/nano-manufacturing of metastable materials for energy Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-28 Xiaoya Cui, Yanchang Liu, Yanan Chen
Structural engineering of metastable nanomaterials with abundant defects has attracted extensive attention in energy-related fields. High-temperature shock (HTS) technique, as a rapid-developing and advanced synthesis strategy, offers significant potential for the rational design and fabrication of high-quality nanocatalysts in an ultrafast, scalable, controllable, and eco-friendly way. In this review
-
Bioprinting of inorganic biomaterials-neural stem cells constructs for multiple tissue regeneration and functional recovery Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-25 Hongjian Zhang, Chen Qin, Zhe Shi, Jianmin Xue, Jianxin Hao, Jinzhou Huang, Lin Du, Hongxu Lu, Chengtie Wu
Tissue regeneration is a complicated process that relies on the coordinated efforts of the nervous, vascular, and immune systems. While the nervous system plays a crucial role in tissue regeneration, current tissue engineering approaches mainly focus on restoring the function of injury-related cells, neglecting the guidance provided by nerves. This has led to unsatisfactory therapeutic outcomes. Herein
-
The anomalous effect of electric field on friction for microscale structural superlubric graphite/Au contact Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-25 Yelingyi Wang, Jin Wang, Tielin Wu, Weipeng Chen, Deli Peng, Zhanghui Wu, Ming Ma, Quanshui Zheng
The current-carrying friction characteristics are crucial for the performance of sliding electrical contact, which plays crucial roles in numerous electrical machines and devices. However, these characteristics are influenced by multiple factors such as material surface quality, chemical reactions, and atmospheric environment, leading to the challenge for researchers to comprehensively considering
-
Thermoelectrocatalysis: an emerging strategy for converting waste heat into chemical energy Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-24 Yuqiao Zhang, Shun Li, Jianming Zhang, Li-Dong Zhao, Yuanhua Lin, Weishu Liu, Federico Rosei
This perspective defines and explores an innovative waste heat harvesting strategy, thermoelectrocatalysis (TECatal), emphasizing materials design and potential applications in clean energy, environmental, and biomedical technologies.
-
Flexible sensors with zero Poisson's ratio Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-24 Xin Huang, Tianzhao Bu, Qingyang Zheng, Shaoyu Liu, Yangyang Li, Han Fang, Yuqi Qiu, Bin Xie, Zhouping Yin, Hao Wu
Flexible sensors have been developed to provide sufficient perception capability for various stimuli. However, the complex deformation, usually results from forces or strains from multi-axes, can be challenging to measure due to the lack of independent perception of multi-axial stimuli. Herein, flexible sensors based on the metamaterial membrane with zero Poisson's ratio (ZPR) are proposed to achieve
-
On-surface synthesis and characterization of polyynic carbon chains Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-23 Wenze Gao, Wei Zheng, Luye Sun, Faming Kang, Zheng Zhou, Wei Xu
Carbyne, an elusive sp-hybridized linear carbon allotrope, has fascinated chemists and physicists for decades. Due to its high chemical reactivity and extreme instability, carbyne was much less explored in contrast to the sp2-hybridized carbon allotropes such as graphene. Herein, we report the on-surface synthesis of polyynic carbon chains by demetallization of organometallic polyynes on the Au(111)
-
Inducing mitochondriopathy-like damages by transformable nucleopeptide nanoparticles for targeted therapy of bladder cancer Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-23 Da-Yong Hou, Ni-Yuan Zhang, Lu Wang, Mei- Yu Lv, Xiang-Peng Li, Peng Zhang, Yue-Ze Wang, Lei Shen, Xiu-Hai Wu, Bo Fu, Peng- Yu Guo, Zi-Qi Wang, Dong-Bing Cheng, Hao Wang, Wanhai Xu
Mitochondriopathy inspired adenosine triphosphate (ATP) depletions has been recognized as a powerful way for controlling tumor growth. Nevertheless, selective sequestration or exhaustion of ATP under complex biological environment remains a prodigious challenge. Harnessing the advantages of in vivo self-assembled nanomaterials, we designed an Intracellular ATP Sequestration (IAS) system to specifically
-
Semisynthesis of homogeneous spike RBD glycoforms from SARS-CoV-2 for profiling the correlations between glycan composition and function Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-21 Farong Ye, Cheng Li, Feng-Liang Liu, Xinliang Liu, Peng Xu, Rong-Hua Luo, Wenping Song, Yong-Tang Zheng, Tianlei Ying, Biao Yu, Ping Wang
Vaccines have been the primary remedy in the global fight against coronavirus disease 2019 (COVID-19). The receptor-binding domain (RBD) of the spike protein, a critical viral immunogen, is affected by the heterogeneity of its glycan structures and relatively low immunogenicity. Here, we describe a scalable synthetic platform that enables the precise synthesis of homogeneously glycosylated RBD, facilitating
-
Stereoselective recognition of morphine enantiomers by μ-opioid receptor Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-20 Yibo Wang, A Van Ngo, Xiaohui Wang
Stereospecific recognition of chiral molecules plays a crucial role in biological systems. The μ-opioid receptor (MOR) exhibits binding affinity towards (-)-morphine, a well-established gold standard in pain management, while it shows minimal binding affinity for the (+)-morphine enantiomer, resulting in a lack of analgesic activity. Understanding how MOR stereo-selectively recognizes morphine enantiomers
-
Bayesian brain computing and the free-energy principle: an interview with Karl Friston Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-18 Wenlian Lu
NSR spoke to a leading theoretical neuroscientist and authority on brain imaging - Karl Friston. The Bayesian mechanics of brain computing gives a unique route to understanding authentic (neuromimetic) intelligence, and more importantly, pointing towards the development of brain-inspired intelligence.
-
Combining cisplatin and a STING agonist into one molecule for metalloimmunotherapy of cancer Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-18 Zhang Shuren, Dongfan Song, Wenhao Yu, Ji Li, Xiaoyu Wang, Yachao Li, Zhao Zihan, Qi Xue, Jing Zhao, Jie P Li, Zijian Guo
Mounting evidence suggests that strategies combining DNA-damaging agents and stimulator of interferon genes (STING) agonists are promising cancer therapeutic regimens because they can amplify STING activation and remodel the immunosuppressive tumor microenvironment. However, a single molecular entity comprising both agents has not yet been developed. Herein, we designed two PtIV-MSA-2 conjugates (I
-
Negative enthalpy alloys and local chemical ordering: a concept and route leading to synergy of strength and ductility Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-17 Zibing An, Tao Yang, Caijuan Shi, Shengcheng Mao, Lihua Wang, Ang Li, Wei Li, Xianmeng Xue, Ming Sun, Yifan Bai, Yapeng He, Fuzeng Ren, Zhouguang Lu, Ming Yan, Yang Ren, Chain-Tsuan Liu, Ze Zhang, Xiaodong Han
Solid solutions are ubiquitous in metals and alloys. Local chemical ordering (LCO) is a fundamental sub-nano/nanoscale process that occurs in many solid solutions and can be used as a microstructure to optimize strength and ductility. However, the formation of LCOs has not been fully elucidated, let alone how to provide efficient routes for designing LCOs to achieve synergistic effects on both superb
-
Lymph node-biomimetic scaffold boosts CAR-T therapy against solid tumor Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-12 Ziyan Liao, Jie Jiang, Wei Wu, Jiaqi Shi, Yanfang Wang, Yuejun Yao, Tao Sheng, Feng Liu, Wei Liu, Peng Zhao, Feifei Lv, Jie Sun, Hongjun Li, Zhen Gu
The limited infiltration and persistence of chimeric antigen receptor (CAR)-T cells is primarily responsible for their treatment deficits in solid tumors. Here, we present a three-dimensional scaffold, inspired by the physiological process of T cell proliferation in lymph nodes. This scaffold gathers the function of loading, delivery, activation, and expansion for CAR-T cells to enhance their therapeutic
-
Deciphering the controlling factors for phase transitions in zeolitic imidazolate frameworks Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-12 Tao Du, Shanwu Li, Sudheer Ganisetti, Mathieu Bauchy, Yuanzheng Yue, Morten M Smedskjaer
Zeolitic imidazolate frameworks (ZIFs) feature complex phase transitions, including polymorphism, melting, vitrification, and polyamorphism. Experimentally probing their structural evolution during transitions involving amorphous phases is a significant challenge, especially at the medium-range length scale. To overcome this challenge, here we first train a deep learning-based force field to identify
-
Method for the extraction of circulating nucleic acids based on MOF reveals cell-free RNA signatures in liver cancer Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-12 Yuqing Sun, Haixin Yu, Shaoqing Han, Ruoxi Ran, Ying Yang, Yongling Tang, Yuhao Wang, Wenhao Zhang, Heng Tang, Boqiao Fu, Boshi Fu, Xiaocheng Weng, Song-Mei Liu, Hexiang Deng, Shuang Peng, Xiang Zhou
Cell-free RNA (cfRNA) allows assessment of health, status, and phenotype of a variety of human organs and is a potential biomarker to non-invasively diagnose numerous diseases. Nevertheless, there is a lack of highly efficient and bias-free cfRNA isolation technologies due to the low abundance and instability of cfRNA. Here, we developed a reproducible and high-efficiency isolation technology for different
-
Meeting the challenges of invasive alien species Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-12 Weijie Zhao
Here we report the Assessment Report on Invasive Alien Species and their Control released by IPBES, and the status of IAS in China.
-
In-situ synthesis of quantum dots in the nucleus of live cells Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-11 Yusi Hu, Zhi-Gang Wang, Haohao Fu, Chuanzheng Zhou, Wensheng Cai, Xueguang Shao, Shu-Lin Liu, Dai-Wen Pang
Cell nucleus is the main site for the storage and replication of genetic material, and the synthesis of substances in the nucleus is rhythmic, regular, and strictly regulated with physiological processes. However, whether exogenous substances, such as nanoparticles, can be synthesized in situ in the nucleus of live cells has not been reported. Here, we have achieved in-situ synthesis of CdSxSe1−x quantum
-
Universal insertion of molecules in ionic compounds under pressure Natl. Sci. Rev. (IF 20.6) Pub Date : 2024-01-10 Feng Peng, Yanming Ma, Chris J Pickard, Hanyu Liu, Maosheng Miao
Using first-principles calculations and crystal structure search methods, we found that many covalently bonded molecules such as H2, H2O, NH3, CH4, and C2H6 may react with NaCl, a prototype ionic solid, and form stable compounds under pressure while retaining their molecular structure. These molecules, despite whether they are homonuclear or heteronuclear, polar or non-polar, small or large, do not