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  • Immobilized optical fiber microprobe for selective and high sensitive glucose detection
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-21
    Yanpeng Li, Hui Ma, Lin Gan, Qi Liu, Zhijun Yan, Deming Liu, Qizhen Sun

    Optical fiber microprobe functionalized with Glucose oxidase (GOD) has been proposed for bio-selective and high-sensitive glucose detection. Taking advantages of the free amine groups of 3-aminopropyl- triethoxysilane (APTES), the enzymes (GOD) are immobilized on the multimode microfiber through covalent interaction. Surface characterization offered by optical microscopy, scanning electron microscope and multiphoton laser scanning microscopy provide detailed evidences about the effect of the bio-functionalization. The fabricated microfiber sensor is immersed into glucose solutions at different concentrations to record and analyze the transmission spectrums from an optical sensing interrogator. The experimental results demonstrate that the resonant wavelength shift is linearly correlated with the glucose concentration in the range of 0-3.0 mg/ml with a response coefficient of 1.74 nm/mg−1 ml−1. Meanwhile, the reported sensor is also proved to be of practical utility by accurately detecting glucose content in animal serum samples. Due to the small size, label-free sensing capacity and excellent practicality, the proposed device has great potential to be applied in the fields like disease diagnosis, clinical analysis and food safety.

    更新日期:2017-09-21
  • Solid state mixed-potential sensors as direct conversion sensors for automotive catalysts
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-21
    Thomas Ritter, Gunter Hagen, Julia Lattus, Ralf Moos

    In order to determine directly the quantity “conversion of a catalyst”, we developed a new YSZ solid-electrolyte based mixed-potential sensor that enables to compare electrochemically two gas compartments. Core of the sensor is a self-heated YSZ disc that provides in the center sufficiently high temperatures for sensing. At the sensor rim, the temperatures are low enough to allow for applying polymer sealings to separate both gas chambers gas tightly. In this study, the YSZ sensor disc compares two gas mixtures emulating the propene concentrations that occur up- and downstream of a diesel oxidation catalyst (DOC). At a temperature of 500 °C at the center of the disc, the changing propene concentrations on one side of the sensor, which emulate a changing propene conversion of the catalyst, are reflected by the sensor signal. Up to a conversion of 90 %, the sensor signals follow a theoretical equation that is derived from mixed-potential theory. For higher propene conversions, the signal differs from that theory. An initial explanation for this may be the catalytic activity of the platinum electrode at these high operation temperatures. This is supported by the fact that when reducing the catalytic activity, which is achieved by reducing the sensing temperature, the sensor signal is meeting more and more the theoretically derived equation. At 425 °C and below, there is no more dependency on the feed gas concentration, and all measured data fit exactly with the above-derived theory, i.e., the sensor signal depends only on the “conversion of the catalyst” and not on the propene concentration. As result, a sensor that measures directly the quantity “conversion” is obtained.

    更新日期:2017-09-21
  • High-performance graphene oxide/vapor-grown carbon fiber composite polymer actuator
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-21
    Naohiro Terasawa, Kinji Asaka
    更新日期:2017-09-21
  • Visible light assisted NO2 sensing at room temperature by CdS nanoflake array
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-21
    Hua-Yao Li, Ji-Won Yoon, Chul-Soon Lee, Kyeorei Lim, Ji-Wook Yoon, Jong-Heun Lee
    更新日期:2017-09-21
  • Graphene Oxide/Poly (N-isopropylacrylamide) Hybrid Film-based Near-infrared Light-driven Bilayer Actuators with Shape Memory Effect
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-20
    Ze Chen, Rui Cao, Sunjie Ye, Yuanhang Ge, Yingfeng Tu, Xiaoming Yang
    更新日期:2017-09-21
  • Novel impedimetric aptasensor for label-free detection of Escherichia coli O157:H7
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-20
    Sergi Brosel-Oliu, Rubén Ferreira, Naroa Uria, Natalia Abramova, Raimundo Gargallo, Francesc-Xavier Muñoz-Pascual, Andrey Bratov

    Microbial safety of drinking water constitutes a major concern in countries at all levels of economic development. Thus, rapid, sensitive and cost effective methods of pathogenic bacteria detection, like common Escherichia coli O157:H7, which can cause important diseases, are highly required.In this work an impedimetric transducer modified with E. coli specific aptamer is studied. To enhance the sensitivity a three-dimensional interdigitated electrode array (3D-IDEA) impedimetric transducer, in which the electrodes are separated by insulating barriers was used. In this sensor chemical reactions at the surface of the barrier provoke electrical charge redistribution which causes changes in the surface conductivity. A DNA aptamer, which recognizes specifically the outer membrane proteins of the E. coli O157:H7, was selected as the biorecognition moiety.Here we report a novel label-free impedimetric aptasensor for detection and quantification of pathogenic E. coli O157:H7 with a low detection limit, good selectivity and short detection time. The developed sensor shows a linear response (R2 = 0.977), proportional to the logarithm of bacterial concentration present in the sample, with the limit of detection (LOD) of about 102 cfu·mL−1. No response of the aptasensor was registered in the presence of other bacterial strains (E. coli k12, Salmonella typhimurium, Staphylococcus aureus), which confirms the selectivity of the suggested detection method. Additionally, the methodology of the aptasensor regeneration was developed, so that the detection may be performed several times with the same sensor. Moreover, suitability of the aptasensor for bacteria detection in real samples was demonstrated with a new approach involving bacteria pre-concentration.

    更新日期:2017-09-21
  • Continuously improved gas-sensing performance of SnO2/Zn2SnO4 porous cubes by structure evolution and further NiO decoration
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-20
    SaiSai Zhang, Guang Sun, Yanwei Li, Bo Zhang, Long Lin, Yan Wang, Jianliang Cao, Zhanying Zhang

    Improving the gas-sensing performance of semiconducting metal oxide nanocomposites by optimizing their structure and composition has attracted an increasing interest. In this paper, a reliable sacrificial template method was developed to fabricate a series of SnO2/Zn2SnO4 (TZTO) nanostructures, including TZTO porous cubes (TZTO-PCs), TZTO porous hollow cubes (TZTO-PHCs), and NiO-decorated TZTO porous hollow cubes (NTZTO-PHCs). ZnSn(OH)6 solid cubes (ZHS-SCs) with the edge-length about 500 nm were first synthesized by a facile sonochemistry method, and then chemically etched in NaOH aqueous solution to prepare ZHS hollow cubes (HCs). By using the as-prepared ZHS-SCs and ZHS-HCs as sacrificial templates, TZTO-PCs, TZTO-PHCs, and NTZTO-PHCs with different NiO contents were easily synthesized, respectively. It was found that through the structure evolution from PC to PHC, the sensitivity of TZTO to ethanol was remarkably improved. Significantly, superior ethanol-sensing properties, such as lower optimal operating temperature, higher sensitivity, and a wider range of response linearity were further achieved by decorating TZTO-PHCs with NiO. The optimal content of NiO in NTZTO-PHCs was determined to be 0.75 mol%. The improved sensing mechanism based on structure and composition evolution for the present NTZTO-PHCs was discussed in detail.

    更新日期:2017-09-20
  • Preparation and gas sensing properties of hierarchical leaf-like SnO2 materials
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-20
    Yiqun Zhang, Dan Li, Longgui Qin, Peilu Zhao, Fengmin Liu, Xiaohong Chuai, Peng Sun, Xishuang Liang, Yuan Gao, Yanfeng Sun, Geyu Lu

    Leaf-like SnO2 hierarchical architectures were successfully synthesized via a facile template-free hydrothermal synthesis method. The observations with field emission scanning electron microscopic and transmission electron microscopy demonstrated that the uniform and independent leaf-like SnO2 architectures were obtained, and each dendrite was consisted by a main stem with two groups of highly symmetric and parallel branch. To investigate the effect of diammonium phosphate and the formation process of hierarchical SnO2 leaf-like microstructure, the controlled experiments of the hydrothermal process with different amounts of diammonium phosphate and different reaction times have been carried out systematically. Based on the experimental results, a possible formation mechanism of SnO2 hierarchical architecture was speculated. In addition, the gas sensing performances of the as-prepared products were investigated and the results revealed that the sensor based on the unique leaf-like SnO2 hierarchical architectures exhibited high response and good selectivity properties to NO2 at low working temperature.

    更新日期:2017-09-20
  • FABRICATION OF NANOCRATER-DECORATED ANODIC ALUMINUM OXIDE MEMBRANES AS SUBSTRATES FOR REPRODUCIBLY ENHANCED SERS SIGNALS
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-20
    Merve Celik, Sevde Altuntas, Fatih Buyukserin

    Despite the potential sensitivity and the wide range of applications for surface-enhanced Raman spectroscopy (SERS), it is not used as a routine detection tool due mainly to the poor reproducibility of the enhanced SERS signals. In order to obtain reproducibly strong SERS data, both lithographic and non-lithographic approaches are intensively investigated to produce large-area nanopatterned SERS substrates displaying periodically arranged arrays of nanostructures. Herein, we report a facile method for the non-lithographic fabrication of plasmonic nanoparticle arrays by utilizing the barrier sides of anodized aluminum oxide (AAO) membranes. The nanobump-decorated surfaces (NBDS) of AAO barrier sides were treated with wet etching to create periodic arrays of nanocraters. Upon coating with an optimized thickness of Au, the nanocrater decorated surfaces (NCDS) displayed intensified SERS signals compared with the NBDS counterparts. This result was also confirmed with simulation studies and it was related to the increased surface roughness for the NCDS substrates. The fabricated Au@NCDS nanoplatforms were stable for extended periods and allowed enhanced and reproducible SERS signals with relative standard deviation values ∼10% from independently prepared samples. Our current studies are focused on the potential use of these SERS substrates for sensing biomarker molecules including myoglobin and troponin-T.

    更新日期:2017-09-20
  • Design of magnetic core–shell Ni@graphene composites as a novel electrochemical sensing platform
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-20
    Xuechou Zhou, Xueling Yan, Zhensheng Hong, Xinyu Zheng, Fei Wang
    更新日期:2017-09-20
  • ppb Level ammonia detection of 3-D PbS quantum dots/reduced graphene oxide nanococoons at room temperature and Schottky barrier modulated behavior
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-20
    Yueli Liu, Haoran Wang, Shuang Yang, Keqiang Chen, Tingqiang Yang, Jin Wei, Jingwen Tian, Wen Chen
    更新日期:2017-09-20
  • Colorimetric determination of Hg(II) by combining the etching and aggregation effect of cysteine-modified Au-Ag core-shell nanorods
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-19
    Jian Zhu, Bing-zheng Zhao, Ying Qi, Jian-Jun Li, Xin Li, Jun-Wu Zhao
    更新日期:2017-09-20
  • Three-dimensional electrochemical DNA biosensor based on 3D graphene-Ag nanoparticles for sensitive detection of CYFRA21-1 in non-small cell lung cancer
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-19
    Mei Chen, Yuanyuan Wang, Huilan Su, Li Mao, Xinni Jiang, Tao Zhang, Xiaozhen Dai
    更新日期:2017-09-20
  • Label-free electrochemical immunosensor based on conductive Ag contained EMT-style nano-zeolites and the application for α-fetoprotein detection
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-19
    Xinran Zhang, Jiao Sun, Jingshi Liu, Hongwei Xu, Biao Dong, Xueke Sun, Tianxiang Zhang, Shihan Xu, Lin Xu, Xue Bai, Shuang Zhang, Svetlana Mintova, Geyu Lu, Hongwei Song
    更新日期:2017-09-20
  • Study of interaction mechanism of metal phthalocyanines dispersed sol-gel glasses with chemical vapours
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-19
    R. Ridhi, G.S.S. Saini, S.K. Tripathi
    更新日期:2017-09-19
  • Generator–Collector Electrochemical Sensor Configurations Based on Track-Etch Membrane Separated Platinum Leaves
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-19
    Hamid Reza Zafarani, Liza Rassaei, Ernst J.R. Sudhölter, Barak D.B. Aaronson, Frank Marken
    更新日期:2017-09-19
  • An InSb-based magnetoresistive biosensor using Fe3O4 nanoparticles
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-19
    Sung Jong Kim, Seung-Woo Lee, Jin Dong Song, Young-Wan Kwon, Kyung-Jin Lee, Hyun Cheol Koo

    A magnetoresistive biosensor was demonstrated using an InSb-based semiconductor channel. The Fe3O4 nanoparticle was linked with a target antigen via a capture antibody in the reagent, and a detection antibody immobilized on an InSb channel was shown to selectively bind to the antigen-capture antibody-nanoparticle complex. The detected magnetic nanoparticles produced a stray magnetic field that induced a change in the resistance of the channel due to the Lorentz force. The antigen concentration was proportional to the number of nanoparticles attached to the sensor surface, and hence could be determined by measuring the magnetoresistance level of the sensing channel. This antigen-antibody reaction sensor was shown to detect an extremely small amount of liver cancer antigen, at a concentration as low as 1 pg/ml. The systematic tests we carried out also confirmed the good selectivity and reusability of this biosensor.

    更新日期:2017-09-19
  • Detection of Contaminants in Water Supply: A Review on State-of-the-Art Monitoring Technologies and Their Applications
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-18
    Syahidah Nurani Zulkifli, Herlina Abdul Rahim, Woei Jye Lau

    Water monitoring technologies are widely used for contaminants detection in wide variety of water ecology applications such as water treatment plant and water distribution system. A tremendous amount of research has been conducted over the past decades to develop robust and efficient techniques of contaminants detection with minimum operating cost and energy. Recent developments in spectroscopic techniques and biosensor approach have improved the detection sensitivities, quantitatively and qualitatively. The availability of in-situ measurements and multiple detection analyses has expanded the water monitoring applications in various advanced techniques including successful establishment in hand-held sensing devices which improves portability in real-time basis for the detection of contaminant, such as microorganisms, pesticides, heavy metal ions, inorganic and organic components. This paper intends to review the developments in water quality monitoring technologies for the detection of biological and chemical contaminants in accordance with instrumental limitations. Particularly, this review focuses on the most recently developed techniques for water contaminant detection applications. Several recommendations and prospective views on the developments in water quality assessments will also be included.

    更新日期:2017-09-19
  • Efficient fabrication of Poly(pyrrole)-nanowires modified via diazonium chemistry on flexible thermoplastics substrates: Application for Cytokines detection
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-18
    Alvaro Garcia-Cruz, Faiza Nessark, Michael Lee, Nadia Zine, Monique Sigaud, Raquel Pruna, Manuel Lopez, Pedro Marote, Joan Bausells, Nicole Jaffrezic, Abdelhamid Errachid

    Poly(pyrrole)-nanowires (PPy-NWs) were efficiently printed by using nano printing on flexible thermoplastics, and then used to device an impedimetric immunosensor. The present pioneering technology allow to create high sensitive and disponsable immunosensor devised using a low cost and simple fabrication. The innovative nanocontact printing uses a PDMS stamp replicated from a CD mold. The PPyNW printing uses controlled chemical polymerization to print PPy-NWs on poly (ethylene terephthalate) and polyether ether ketone surfaces. Atomic force microscopy analysis of PPyNW revealed a width, height and a separation length of 125 ± 8 nm, 377 ± 5 nm and 172 ± 4 nm, respectively. The PPy-NWs were characterized by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS) and electrochemical impedance spectroscopy (EIS). The XPS results evidenced the covalent bonding between the thermoplastic surface and the PPyNWs. As a final point, the immunosensor was tested for the quantification of Interleukin 6 recombinant human (IL6, Ag) using EIS. The PPy-NWs were functionalized via diazonium coupling reaction and carbodiimide crosslinker chemistry for the immobilization of Anti-human IL-6 monoclonal antibodies (IL6 mAb’s). The developed immunosensor exhibited a sensitivity of 0.013 (pg/mL)−1 (linear fitting at R2 = 0.99) and limit of detection (LOD) of 0.36 pg/mL in a linear range of 1–50 pg/mL for Ag IL-6, with a relative standard deviation percentage (RSD%) at 7.6%.

    更新日期:2017-09-19
  • NIR-Responsive DNA Hybridization Detection by High Efficient FRET from 10-nm Upconversion Nanoparticles to SYBR Green I
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-18
    Bo Wu, Ziquan Cao, Qing Zhang, Guojie Wang
    更新日期:2017-09-19
  • Development of Solution Processible Organic-inorganic Hybrid Materials with Core-shell Framework for Humidity Monitoring
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-18
    Hongran Zhao, Tong Zhang, Rongrong Qi, Jianxun Dai, Sen Liu, Teng Fei, Geyu Lu

    A novel organic-inorganic hybrid material with the core-shell framework was prepared by modifying the poly(vinylsulfonic acid, sodium salt) (PSS) on vinyl functionalized silica nanoparticles (VSNs) via the free radical polymerization. SNs with different contents of PSS were prepared and the structures were carefully characterized. The hybrid material could enhance the durability of PSS under high humidity environment. Meanwhile, the SNs skeleton provides interstitial channels in the PSS@SNs films, which are available for water molecules transport. The PSS coated SNs (PSS@SNs) films were formed by drop-coating and their sensing properties were investigated. The impedance of the optimal humidity sensor changed more than four orders of magnitude over the relative humidity range of 33–95%, with good linearity under semi-logarithm scale (R2 = 0.950) and a small humidity hysteresis of 2% RH. The obtained sensor also showed rapid response to humidity change (the response and recovery time were 2 and 65 s, respectively). Finally, the resultant sensor was explored for respiratory rate monitoring.

    更新日期:2017-09-19
  • A whole cell bio-optode based on immobilized nitrite-degrading microorganism on the acrylic microspheres for visual quantitation of nitrite ion
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-18
    Siti Nur Syazni Mohd Zuki, Ling Ling Tan, Nina Suhaity Azmi, Lee Yook Heng, Kwok Feng Chong, Saiful Nizam Tajuddin
    更新日期:2017-09-19
  • Bimetallic Pd@Au Nanorods based Ultrasensitive Acetylcholinesterase Biosensor for Determination of Organophosphate Pesticides
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-18
    Xiong Lu, Lu Tao, Dandan Song, Yan Li, Faming Gao
    更新日期:2017-09-19
  • Novel research on okadaic acid field-based detection using cell viability biosensor and Bionic e-Eye
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-18
    Kaiqi Su, Longjie Zhong, Yuxiang Pan, Jiaru Fang, Quchao Zou, Zijian Wan, Ping Wang

    A novel bioanalysis method for sensitive, rapid and field-based detection of okadaic acid (OA) is in great demand for environmental monitoring and food security. In this study, we reported a biosensing system consisting of a smartphone-based system and cell viability biosensor (CVB) for OA spot fast detection. CVB was constructed by combing living cells and cell counting kit (CCK-8). Thereinto, living cells could be used as reagent without adherent culture on the device surface, and adherent cells and suspension cells were both applicable for cell type selection. The smartphone-based system – bionic electronic eye (Bionic e-Eye) was composed of portable illumination provider and smartphone. The homemade application program (App) – iPlate Monitor integrated the software functions of real-time image acquisition and analysis, data display and storage and instant data sharing. In the measurement, the system was demonstrated to detect OA at concentration as low as 3.4083 μg/L and 13.4456 μg/L by using HepG2 and THP-1 cells, respectively. In addition, this system distinguished OA versus different marine toxins such as gonyautoxin2&3 (GTX2&3) and brevetoxin-2 (PbTx-2) in high specificity. Consequently, the smartphone-based biosensing platform provided a convenient, low-cost, easy-to-use and efficient approach for spot rapid detection of marine toxins such as OA.

    更新日期:2017-09-19
  • Enzyme-free amperometric method for rapid determination of histamine by using surface oxide regeneration behavior of copper electrode
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-18
    Ya-Tin Lin, Chi-Hao Chen, Meng Shan Lin
    更新日期:2017-09-19
  • Vapor sensing performance as a diagnosis probe to estimate the distribution of multi-walled carbon nanotubes in poly(lactic acid)/polypropylene conductive composites
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-18
    Yilong Li, Yanjun Zheng, Pengfei Zhan, Guoqiang Zheng, Kun Dai, Chuntai Liu, Changyu Shen

    Multi-walled carbon nanotubes (MWCNT)/poly (lactic acid) (PLA)/polypropylene (PP) with different polymer blend ratios were fabricated by melt processing method. When fixed the MWCNT content at 1.0 wt. %, A6P4 (PLA/PP 60w/40w) showed the lowest resistivity, which is attributed to the formation of a co-continuous structure. According to the thermodynamics prediction, MWCNT is estimated to be selectively distributed in PLA phase. To further investigate the MWCNT localization behavior in polymer blend, a two-step compounding sequence approach was utilized to fabricate Pre-PLA (i.e., MWCNT were firstly mixed with PLA) and Pre-PP composites. Morphology observation and rheology tests were then carried out to demonstrate the MWCNT distribution in the composites. Vapor sensing behaviors of CPCs towards organic vapors with different polarity were investigated in detail. CPCs with higher PLA content showed a higher responsivity to dichloromethane, a ‘good solvent’ to PLA. CPCs containing higher PP content exhibited a higher responsivity towards xylene due to the strong interaction between PP and the xylene vapor. While for cyclohexane, a ‘poor solvent’ to PLA and PP, all the CPCs demonstrate a low responsivity. Interestingly, the vapor sensing feature can be used to testify the MWCNT localization in the polymer blend as a diagnosis probe.

    更新日期:2017-09-19
  • Integrated H2 nano-sensor array on GaN honeycomb nanonetwork fabricated by MEMS-based technology
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-18
    Aihua Zhong, Takashi Sasaki, Ping Fan, Dongping Zhang, Jingting Luo, Kazuhiro Hane

    Manipulation of nanostructures is difficult, making it tough to fabricate nano-device, let alone the fabrication of integrated nano-sensor. In this paper, a monolithically integrated H2 nano-sensor array on a GaN honeycomb nanonetwork (GaN-HN) are proposed and realized by combining GaN-HN MBE growth with standard silicon micromachining techniques. For each H2 nano-sensor unit, a H2 sensing element, a reference sensor, a micro-heater, a resistive temperature detector (RTD), and the current-circuit are integrated on a single chip. The H2 sensing element Pt/GaN-HN Schottky diode was well fabricated on the suspended GaN-HN with 20 nm out-of-plane deformation and 0.0016 mm−1 curvature. An Au/GaN-HN Schottky diode is proposed as the reference sensor and it is effective to reduce the output signal shift caused by ambient fluctuation to 20%. Moreover, the micro-heater on the free standing GaN-HN has high heating efficiency with fast heating and cooling time (2.3 ms and 2.5 ms, respectively). In addition, the performance of H2 nano-sensor unit at room temperature and at 75 °C heated by the integrated micro-heater with low power of 5.8 mW was recorded and discussed. At 75 °C, the response time τres and the recovery time τrec of the integrated H2 sensor are significantly shortened by a factor of 3.

    更新日期:2017-09-19
  • An electrochemical method for evaluation the cytotoxicity of fluorene on reduced graphene oxide quantum dots modified electrode
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-17
    Shi Zhou, Peng Guo, Jinlian Li, Lingren Meng, Hongfu Gao, Xing Yuan, Dongmei Wu
    更新日期:2017-09-19
  • Efficient Wide Range Electrochemical Bisphenol-A Sensor by Single Dendritic Mesoporous Platinum Nanoparticles on Screen-Printed Carbon Electrode
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-17
    Kyubin Shim, Jeonghun Kim, Mohammed Shahabuddin, Yusuke Yamauchi, Md Shahriar Al Hossain, Jung Ho Kim
    更新日期:2017-09-19
  • Design for a Small Molecule Based Chemosensor Containing Boron and Pyridine moieties to Detect HF
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-17
    Ying Hu, Mahnseok Kye, Ji Young Jung, Yong-beom Lim, Juyoung Yoon
    更新日期:2017-09-19
  • Aptamer-based F0F1-ATPase biosensor for Salmonella typhimurium detection
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-17
    Nuo Duan, Weijia Sun, Shijia Wu, Lihong Liu, Xu Hun, Zhouping Wang

    A novel biosensor was developed by conjugating Salmonella typhimurium aptamer with the “rotator” ε-subunit of F0F1–ATPase within chromatophores through an anti-ε-subunit antibody–biotin–avidin–biotin–aptamer linker to capture bacteria. The bacterial load decreased the rotation rate of F0F1-ATPase, which led to the decrease in ATP synthesis. The detection of S. typhimurium was based on proton flux change driven by the F0F1-ATPase-mediated ATP-synthesis, which was indicated by fluorescence probe, monitored by a fluorescence spectrometer. Under optimal conditions, the correlation between the relative fluorescence signal intensity and the concentration of S. typhimurium was observed to be linear within the range of 101 to 104 cfu·mL−1 (R2 = 0.9944). The limit of detection for S. typhimurium was as low as 10 cfu·mL−1. The results demonstrate that the F0F1-ATPase molecular motor biosensor can specifically detect S. typhimurium at low concentration, and will be a convenient, quick, and promising tool for detecting pathogens.

    更新日期:2017-09-19
  • Metallic nickel nitride nanosheet: An efficient catalyst electrode for sensitive and selective non-enzymatic glucose sensing
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-15
    Fengyu Xie, Tingting Liu, Lisi Xie, Xuping Sun, Yonglan Luo

    It is significantly important to design enzyme-free electrocatalyst for sensitive and selective detection of glucose (Glu). In this paper, we report that metallic nickel nitride nanosheet on Ti mesh (Ni3N NS/Ti) behaves as an efficient three-dimensional catalyst electrode for Glu electro-oxidation under alkaline conditions. We further demonstrate the use of such Ni3N NS/Ti as a non-enzymatic electrochemical Glu sensor superior in analytical performances. The introduction of the Ni3N NS/Ti can provide a high surface area and lead to high sensitivity to Glu. This sensor shows a fast amperometric response toward Glu and can achieve steady state current density within 5 s, a detection range of 0.2 μM to 1.5 mM, a detection limit of 0.06 μM (S/N = 3), a response sensitivity of 7688 μA mM−1 cm−2, and satisfactory selectivity and reproducibility. In addition, it also works effectively for Glu detection in human blood serum, promising its application toward determination of Glu in real samples.

    更新日期:2017-09-15
  • A polydiacetylenes-based colorimetric and fluorescent probe for L-arginine and L-lysine and its application for logic gate
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-15
    Zhijie Zhang, Tingwen Wei, Yahui Chen, Tiantian Chen, Bo Chi, Fang Wang, Xiaoqiang Chen
    更新日期:2017-09-15
  • Colorimetric detection of methionine based on anti-aggregation of gold nanoparticles in the presence of melamine
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-15
    Peng-Cheng Huang, Nan Gao, Jian-Fang Li, Fang-Ying Wu
    更新日期:2017-09-15
  • Recent advances in AC electrokinetic sample enrichment techniques for biosensor development
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-15
    Alinaghi Salari, Michael Thompson

    Integration of biosensing techniques with microfluidics has enabled less sample consumption and increased sensitivity. In addition, it offers a potential improvement with respect to slow diffusion-limited sensing, as well as the incorporation of several sample handling parts into a single lab-on-a-chip device. One highly efficient technique in microfluidics that can be utilized in pre-sensing sample preparation steps such as sorting, separation, trapping, enrichment, and labelling is electrokinetics. AC electroosmosis, AC electrothermal, and dielectrophoresis are among the highly applicable electrokinetic methods used for pre-sensing sample preparation for enhancing sensitivity, limit-of-detection, and selectivity of biosensing devices. In this review article, we focus on these three electrokinetic techniques used for sample enrichment in the field of biosensing technology. First, the working principals of electrothermal, electroosmosis, and dielectrophoresis are characterized, and then their recent advances and major achievements in sample enrichment for biosensors are discussed

    更新日期:2017-09-15
  • Dual-channel sensing of CO2: reversible solution-gel transition and gelation-induced fluorescence enhancement
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-15
    Xin Zhang, Huifang Mu, Haimiao Li, Yu Zhang, Meng An, Xuhong Zhang, Juyoung Yoon, Haitao Yu
    更新日期:2017-09-15
  • NiFe layered double hydroxide nanosheets as an efficiently mimic enzyme for colorimetric determination of glucose and H2O2
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-15
    Tianrong Zhan, Jingxia Kang, Xianjun Li, Lei Pan, Guangjiu Li, Wanguo Hou

    The ultrathin NiFe-layered double hydroxide nanosheets (NiFe-LDHNS) were prepared by exfoliating bulk LDH in L-asparagine aqueous medium. The transmission electron microscopy and atomic force microscopy results reveal that NiFe-LDHNS have about 200 ∼ 300 nm lateral size and less than 2 nm thickness with the broken edges rather than the original hexagon of hydrotalcite. The peroxidase-like activity of the 2D NiFe-LDHNS was investigated by using oxidation of the peroxidase substrate 3,3′,5,5′-tetramethylbenzidine in presence of H2O2. The 2D NiFe-LDHNS exhibited the superior enzyme mimic activity to the bulk NiFe-LDH, which was attributed to the more exposed active sites and more accessible inner surface of single or several layers. Thus, a simple and sensitive non-enzyme biosensor was developed for colorimetric detection of H2O2 and glucose. The proposed method was successfully applied to glucose detection in real samples with satisfactory results.

    更新日期:2017-09-15
  • Multiselective visual gas sensor using nickel oxide nanowires as chemiresistor
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-14
    Matteo Tonezzer, Le T.T. Dang, Huy Q. Tran, Salvatore Iannotta

    Nowadays the detection of unwanted volatile compounds in air is increasingly important in a wide range of fields. Metal oxide nanosensors are extremely small and cheap devices that could be integrated in any application, but their single resistance response make them non-selective. For this reason, sensor arrays are used where pollutant recognition is needed. Unfortunately, these electronic noses, consisting of different active materials, are complex and expensive. Here, we present a simple visual nanosensor that can detect and recognize selectively several volatile compounds at a relatively low temperature (200–300 °C). The dynamic resistance of a conductometric NiO nanosensor is simply transformed in a visual output that allows to recognize different gases and their concentration with a quick look. This way, one single nanostructured metal oxide can act as a sensitive and selective electronic nose, using the powerful post-processing given by the human eyes and brain. The sensor has proven to discriminate 8 different gases diluted in air (1 oxidizing and 7 reducing) and their respective concentration.

    更新日期:2017-09-15
  • Palladium-containing polymers as solid hybrid sensory materials (water-soluble polymers, films and smart textiles) for the colorimetric detection of cyanide in aqueous and gas phases
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-14
    Miriam Trigo-López, Asunción Muñoz, Aránzazu Mendía, Saturnino Ibeas, Felipe Serna, Félix Clemente García, José Miguel García
    更新日期:2017-09-15
  • Down’s syndrome screening with hydrogel photonic barcodes
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-14
    Hui Xu, Jingyin Zhang, Yueshuang Xu, Huan Wang, Fanfan Fu, Qionghua Xu, Yunlang Cai

    For giving birth to a healthy baby without Down’s syndrome, screening the level of alpha fetoprotein (AFP) and free-beta human chorionic gonadotropin (β-hCG) in maternal serum has been a routine examination for all gravidas. However, many assays only detect one target once time, which requires large samples and is low-throughput and costly. Herein, we describe a sensitive and inexpensive multiplex detection assay based on inverse opal structure hydrogel barcodes with poly(ethylene glycol) diacrylate (PEG-DA), poly(ethylene glycol) (PEG) and acrylic acid (AA) hybrid components. The polymerized PEG-DA hydrogel could guarantee the stabilities of the inverse opal structure, while the AA could offer active carboxyl groups for the probe immobilization. In addition, the interconnected pores of the inverse opal structure caused by PEG could also provide channels for biomolecules diffusing and reaction into the voids of the barcodes. The immunoassay results of our detection on AFP and β-hCG showed acceptable accuracy and detection reproducibility, and the results were in acceptable agreement with those from common clinic method for the detection of practical clinical samples. Thus, the new platform is apparently suitable for multiplex detection of Down’s syndrome.

    更新日期:2017-09-15
  • A fluorescent probe for investigating metabolic stability of active transplatin analogues
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-14
    Jacek L. Kolanowski, Lucy J. Dawson, Linda Mitchell, Zelong Lim, Marcus E. Graziotto, Wojciech K. Filipek, Trevor W. Hambley, Elizabeth J. New
    更新日期:2017-09-15
  • Rapid Microfluidic Paper-Based Platform for Low Concentration Formaldehyde Detection
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-14
    John Mello Camille C. Guzman, Lemmuel L. Tayo, Chan-Chiung Liu, Yao-Nan Wang, Lung-Ming Fu
    更新日期:2017-09-15
  • A simple “turn-on” detection platform for trypsin activity and inhibitor screening based on N-acetyl-L-cysteine capped CdTe Quantum Dots
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-14
    Fanping Shi, Lei Wang, Yan Li, Yu Zhang, Xingguang Su
    更新日期:2017-09-15
  • Linked bridge hybridizing-induced split G-quadruplex DNA machine and its application to uracil-DNA glycosylase detection
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-14
    Xiao Fang Zhang, Na Li, Yu Ling, Li Tang, Nian Bing Li, Hong Qun Luo
    更新日期:2017-09-15
  • Fabrication and evaluation of sulfanilamide-imprinted composite sensors by developing a custom-tailored strategy
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-14
    Xiao Wei, Guodan Xu, Chengcheng Gong, Fang Qin, Xinghui Gong, Chen Li
    更新日期:2017-09-15
  • Method to prevent backflow in a capillarity network for bioassays: exploiting time constant ratios
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-14
    Yonghun Lee, Munseok Choi, Sung-Jin Kim
    更新日期:2017-09-15
  • Fluorescent Silicon Nanoparticles-Based Ratiometric Fluorescence Immunoassay for Sensitive Detection of Ethyl Carbamate in Red Wine
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-14
    Lin Luo, Yang Song, Chengzhou Zhu, Shaofang Fu, Qiurong Shi, Yuan-Ming Sun, Baozhu Jia, Dan Du, Zhen-Lin Xu, Yuehe Lin

    Herein, a ratiometric fluorescence (RF) enzyme-linked immunosorbent assay (RF-ELISA) for sensitive detection of ethyl carbamate (EC) was first developed by introducing fluorescent silicon nanoparticles (Si NPs) into the chromogenic substrate system (o-phenylenediamine (OPD)/H2O2) of a conventional horseradish peroxidase (HRP)-based ELISA platform to assemble a RF-based signal output system. For this system, the fluorescence of Si NPs at 440 nm (I440) was acted as the reference signal which could be efficiently quenched by 2,3-diaminophenazine (DAP), the HRP-catalyzed oxidation product of OPD; Meanwhile, the fluorescence of DAP at 570 nm (I570) was served as response signal. Therefore, variation in the amount of HRP labeled secondary antibody bound on the microplate which is associated with antibody-antigen recognition events in conventional HRP-based ELISA could be transferred into a more sensitive RF signal (I570/I440). On the basis of monoclonal antibody (mAb) which could specifically recognize EC derivative, xanthyl ethyl carbamate (XEC), a Si NPs-based RF-ELISA for EC via a simple pre-analysis derivatization was developed. When detecting the EC content in red wine, this method exhibits a working range from 3.9 to 105.0 μg/L and a limit of detection (LOD) of 2.6 μg/L with excellent specificity, accuracy and reproducibility. The sensitivity is approximately 33-fold higher than of traditional colorimetric ELISA. The proposed Si NPs-based RF-ELISA is not only highly suitable for screening EC in a large number of samples, but also provides a potential platform for high-throughput and sensitive determination of other analytes for food safety monitoring.

    更新日期:2017-09-15
  • Controllable synthesis of copper sulfide for nonenzymatic hydrazine sensing
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-14
    Ziyin Yang, Sai Zhang, Xiaohui Zheng, Yanyi Fu, Jianbin Zheng
    更新日期:2017-09-14
  • Quantifying acetaldehyde in cider using a Mn(III)-substituted polyoxotungstate coated acoustic wave sensor
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-14
    Marta I.S. Veríssimo, José A.F. Gamelas, Mário M.Q. Simões, Dmitry V. Evtuguin, M. Teresa S.R. Gomes

    A new method for the quantification of acetaldehyde in a water matrix, namely commercial ciders, was developed using solid phase micro-extraction (SPME) followed by detection with a coated acoustic wave sensor. The sensitive coating was a polyoxometalate salt specially synthesised for this application, a compound tailored to be insoluble in water. Although the sample gaseous flow reaching the sensor needed to be dried, as the sensor itself responds to water, there was no sensitivity deterioration after contacting with water vapour, as frequency recover under dried nitrogen carrier was complete. Calibration lasted at least for two months. Comparing this sensor with the analogue previously coated with the soluble decamolybdodivanado phosphoric acid, the main advantage comes from the superior stability, and the possibility of keeping it in a wet environment without deterioration.The flow injection analysis (FIA) methodology here reported for the first time for acetaldehyde analysis in cider, allowed to obtain results not statistically different from the ones obtained with Gas Chromatography-Flame Ionization Detection (GC-FID) (α=0.05). Besides, the new methodology does not use expensive instrumentation and the analysis time is similar. Detection limit of this new method was 2.0 mg L−1, and quantification limit was 6.7 mg L−1, not much higher than the values of 1.4 mg L−1 and 4.6 mg L−1, respectively, of the GC-FID.

    更新日期:2017-09-14
  • Feedback control system for large scale 2D digital microfluidic platforms
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-14
    Chunqiao Li, Kaidi Zhang, Xubo Wang, Jian Zhang, Hong Liu, Jia Zhou

    As a promising candidate of point-of-care devices (POC), digital microfluidic (DMF), driven by the electrowetting-on-dielectric (EWOD), has been developed quickly in recent years. However, flourishing functions require more controlled electrodes, i.e., a large-scale EWOD. Limited to cost, complexity and flexibility, existing control techniques lack strength in meeting the need of controlling increasing number of electrodes. Here, inspired by the active matrix electrowetting-on-dielectric (AM-EWOD), we present a “direct-address based on cross-control” (DACC) method, which can easily realize N + M pins controlling N × M electrodes and guarantee the control flexibility meanwhile. Moreover, combining with impedance detection technique, we set up a cheap and portable cyberphysical system. The system’s software, written in JAVA, has a user-friendly interface and can sense all sites of the DMF in real-time and auto-design routes for droplets to bypass barriers. This novel integrated digital microfluidic system shows great potential for developing low-cost, portable, and automated EWOD DMFs in large-scale.

    更新日期:2017-09-14
  • Developing CH4 Detection Limit at λ=1.654 μ m by Suppressing Optical Interference Fringes in Wavelength Modulation Spectroscopy
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-14
    Wenke Liang, Yunfeng Bi, Qiang Zhou, Xiaozhou Dong, Tieliang Lv

    Optical fringes tend to cause difficulty in gas detection based on wavelength modulation spectroscopy (WMS). In this article, we introduce a convenient fringes suppression method. Through modulation depth optimization and two-frequency modulation technology, we substantially improve the CH4 detection limit. Our experiment adopts a distributed feedback laser operated at λ=1.654 μ m in an open-path environment. The fluctuation of the sensor measurement is dramatically reduced by approximately 10-20 times. The minimum detection limit of the open-path environment improves to 130 ppb m for a 50-minute period. Compared with other previously reported near-infrared CH4 detection systems, our proposed method improves the detection limit further. In contrast to traditional fringe suppressing methods, our method has more advantages in CH4 detection in open-path environments.

    更新日期:2017-09-14
  • Adsorption Characteristics of DNA Nucleobases, Aromatic Amino Acids and Heterocyclic Molecules on Silicene and Germanene Monolayers
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-14
    Tanveer Hussain, Hakkim Vovusha, Thanayut Kaewmaraya, Vittaya Amornkitbamrung, Rajeev Ahuja

    Binding of DNA/RNA nucleobases, aromatic amino acids and heterocyclic molecules on two-dimensional silicene and germanene sheets have been investigated for the application of sensing of biomolecules using first principle density functional theory calculations. Binding energy range for nucleobases, amino acids and heterocyclic molecules with both the sheets have been found to be (0.43-1.16 eV), (0.70-1.58 eV) and (0.22-0.96 eV) respectively, which along with the binding distances show that these molecules bind to both sheets by physisorption and chemisorption process. The exchange of electric charges between the monolayers and the incident molecules has been examined by means of Bader charge analysis. It has been observed that the introduction of DNA/RNA nucleobases, aromatic amino acids and heterocyclic molecules alters the electronic properties of both silicene and germanene nano sheets as studied by plotting the total (TDOS) and partial (PDOS) density of states. The DOS plots reveal the variation in the band gaps of both silicene and germanene caused by the introduction of studied molecules. Based on the obtained results we suggest that both silicene and germanene monolayers in their pristine form could be useful for sensing of biomolecules.

    更新日期:2017-09-14
  • Design of a novel FRET based fluorescent chemosensor and their application for highly sensitive detection of nitroaromatics
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-14
    Payal Taya, Binoy Maiti, Vishal Kumar, Priyadarsi De, Soumitra Satapathi
    更新日期:2017-09-14
  • Influence of relative humidity on the electrical response of PEDOT:PSS based organic field-effect transistor
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-14
    Qayyum Zafar, Shahino Mah Abdullah, Mohamad Izzat Azmer, Mansoor Ani Najeeb, Karwan Wasman Qadir, Khaulah Sulaiman

    We have investigated the influence of relative humidity on the electrical response of a bottom gate organic field-effect transistor (OFET) with poly(3,4-ethylenedioxythiophene)/poly(4-styrene sulfonate) (PEDOT:PSS) as an active channel material. For sensor fabrication, the organic polymer PEDOT:PSS has been spun-cast on highly doped n-Si wafer with preliminary thermally deposited gold, source and drain electrodes. The structural characterization and surface morphology study of active layer has been performed by XRD and FESEM, respectively. From the transfer characteristic curve, the p-type hole conductivity in PEDOT:PSS thin film is confirmed. Whereas from the output current-voltage (I–V) characteristic of the OFET, the Ion/Ioff ratio has been measured to be ∼2.6, when operated at relative humidity (RH) ∼60%. The humidity sensing characteristics of the OFET have further been investigated by exposing the proposed OFET to varied RH levels (40–80% RH) at room temperature (26.2 °C). Within the humidity range examined, the channel current has been observed to amplify by nearly 29.4 times of its magnitude.

    更新日期:2017-09-14
  • PODS-covered PDA film based formaldehyde sensor for avoiding humidity false response
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-14
    Luyu Wang, Yongpeng Yu, Qun Xiang, Jin Xu, Zhixuan Cheng, Jiaqiang Xu

    To avoid false response caused by increase of environmental humidity is important for hydrophilic polydopamine (PDA) based QCM formaldehyde sensor. In order to achieve this purpose, superhydrophobic polymerized n-octadecylsiloxane (PODS) nanostructure is used to cover the surface of PDA film to prevent false response from happening. Compared with pristine PDA based QCM sensor, the sensor based on PODS-PDA composite sensing material shows satisfactory performance on avoiding false response and long-term stable formaldehyde sensing properties. This novel strategy offers a new method to reduce probability of false response resulted from humidity change.

    更新日期:2017-09-14
  • NH2-rich Carbon Quantum Dots: A protein-responsive probe for detection and identification
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-14
    R.M. Freire, Ngoc D.B. Le, Ziwen Jiang, Chang Soo Kim, Vincent M. Rotello, P.B.A. Fechine
    更新日期:2017-09-14
  • A simple, sensitive and reduced cost paper-based device with low quantity of chemicals for the early diagnosis of Plasmodium falciparum malaria using an enzyme-based colorimetric assay
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-13
    Glauco Pilon dos Santos, Cátia Crispilho Corrêa, Lauro Tatsuo Kubota

    In this study, we report the development of a paper-based platform with low amount of reagents for the detection of the histidine-rich protein 2 by an enzyme-based colorimetric assay aiming for the early diagnosis of Plasmodium falciparum malaria. A CO2 laser cutter was used for the fabrication of the device in a simple layout suitable to perform the lateral flow assay, which consisted in a region for sample addition, a detection zone and an absorbent pad, all of which were linked by microfluidic channels. Investigations related to the performance of the sandwich immunoassay in the nitrocellulose membrane shown that the blocking and washing steps are essential to promote efficient antigen-antibody recognition and to generate reliable results, avoiding misinterpretations. Several parameters were also evaluated and the experimental conditions were optimized: concentration and incubation time with the capture antibody (50 μg mL−1 and 5 minutes, respectively); BSA solution at 1.5% (w/v) containing 0.1% (v/v) Tween 20 for blocking the nitrocellulose and 10 minutes as the incubation time; 10 mmol L−1 Tris-HCl buffer solution at pH 7.4 containing 0.15 mol L−1 NaCl and 0.1% (v/v) Tween 20 for washing the device before adding the ready to use TMB substrate at the detection zone. The system demonstrated a good sensitivity and detectability reaching a visual and calculated limit of detection of 5.0 ng mL−1 (65 parasites μL−1) and 4.5 ng mL−1 (59 parasites μL−1) respectively, a clinically relevant concentration that should be sufficient to identify the disease in the appearance of the first symptoms and with the advantage of not needing to use nanostructures or other strategy for signal amplification beyond the enzyme.

    更新日期:2017-09-13
  • Synthesis of catalytically active multielement-doped carbon dots and application for colorimetric detection of glucose
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-13
    Bin Wang, Feng Liu, Yuanya Wu, Yanfen Chen, Bo Weng, Chang Ming Li

    A novel multielement-doped carbon dots (ME-CDs) were synthesized by simply hydrothermal treatment of animal blood. Results revealed that the prepared carbon dots were mainly constituted of carbon, oxygen and nitrogen elements with trace amount of iron and sulfur elements, illustrating strong fluorescence with a quantum yield of 32.6%. The as-prepared carbon dots displayed excellent peroxidase-like catalytic activities attributed to the doped iron elements in the ME-CDs. The nanodots could be utilized to fabricate a colorimetric sensor for glucose detection and demonstrated good sensitivity and specificity. This work provides a facile strategy for the synthesis of catalytically active carbon dots and building of colorimetric sensor.

    更新日期:2017-09-13
  • Efficient hierarchical mixed Pd/SnO2 porous architecture deposited microheater for low power ethanol gas sensor
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-12
    Li Xiao, Shengrui Xu, Geng Yu, Shantang Liu
    更新日期:2017-09-12
  • Fe3+ doped ZnO-Ag photocatalyst for photoelectrochemical sensing platform of ultrasensitive Hg2+ detection using exonuclease III-assisted target recycling and DNAzyme-catalyzed amplification
    Sens Actuators B Chem. (IF 5.401) Pub Date : 2017-09-11
    Bing Zhang, Hongyun Meng, Xue Wang, Jing Li, Honghong Chang, Wenlong Wei

    Herein we designed a novel photoelectrochemical sensing platform based on Fe3+ doped ZnO-Ag photocatalyst (Fe3+/ZnO-Ag) for ultrasensitive Hg2+ detection by using exonuclease III-assisted target recycling and DNAzyme-catalyzed amplification. Firstly, Fe3+/ZnO-Ag was synthesized to provide photocurrent under visible light irradiation. Secondly, target Hg2+ was determined by hairpin DNA probes on the Fe3+/ZnO-Ag modified ITO based on T-Hg2+-T, and then Hg2+ was released by the digestion of exonuclease III to double-stranded DNA. Finally, the photocurrent markedly decreased due to catalysis of hemin/G-quadruplex toward 4-chloro-1-naphthol. Under optimal conditions, the photocurrents were linearly related to Hg2+ concentrations form 0. 5 nM to 100 nM with a detection limit of 0. 1 nM at the 3Sblank criterion. More importantly, the developed biosensor exhibited good selectivity, repeatability, and stability, meanwhile, this analysis platform held great potential for testing real water samples in future.

    更新日期:2017-09-11
Some contents have been Reproduced with permission of the American Chemical Society.
Some contents have been Reproduced by permission of The Royal Society of Chemistry.
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