-
Natural language instructions induce compositional generalization in networks of neurons Nat. Neurosci. (IF 25.0) Pub Date : 2024-03-18 Reidar Riveland, Alexandre Pouget
-
Local origin of excitatory–inhibitory tuning equivalence in a cortical network Nat. Neurosci. (IF 25.0) Pub Date : 2024-03-15 Adrian J. Duszkiewicz, Pierre Orhan, Sofia Skromne Carrasco, Eleanor H. Brown, Eliott Owczarek, Gilberto R. Vite, Emma R. Wood, Adrien Peyrache
-
Real-time analysis of large-scale neuronal imaging enables closed-loop investigation of neural dynamics Nat. Neurosci. (IF 25.0) Pub Date : 2024-03-11 Chun-Feng Shang, Yu-Fan Wang, Mei-Ting Zhao, Qiu-Xiang Fan, Shan Zhao, Yu Qian, Sheng-Jin Xu, Yu Mu, Jie Hao, Jiu-Lin Du
-
In conversation with Igor Adameyko Nat. Neurosci. (IF 25.0) Pub Date : 2024-03-12 Elisa Floriddia
As Nature Neuroscience celebrates its 25th anniversary, we are having conversations with both established leaders in the field and those earlier in their careers to discuss how the field has evolved, and where it is heading. This month, we are talking to Igor Adameyko (Department Chair at the Center for Brain Research of the Medical University of Vienna, Austria, and a group leader at the Karolinska
-
Liprin-α proteins are master regulators of human presynapse assembly Nat. Neurosci. (IF 25.0) Pub Date : 2024-03-12 Berta Marcó de la Cruz, Joaquín Campos, Angela Molinaro, Xingqiao Xie, Gaowei Jin, Zhiyi Wei, Claudio Acuna, Fredrik H. Sterky
-
Identification of a cold sensor in peripheral somatosensory neurons Nat. Neurosci. (IF 25.0) Pub Date : 2024-03-11
-
The kainate receptor GluK2 mediates cold sensing in mice Nat. Neurosci. (IF 25.0) Pub Date : 2024-03-11 Wei Cai, Wenwen Zhang, Qin Zheng, Chia Chun Hor, Tong Pan, Mahar Fatima, Xinzhong Dong, Bo Duan, X. Z. Shawn Xu
-
Learning with baby Nat. Neurosci. (IF 25.0) Pub Date : 2024-03-07 Rebecca Wright
The rate at which young children learn new words astounds care-givers and scientists alike. Most models of early language acquisition have only been tested in laboratory settings using highly controlled stimuli. In a recent publication in Science, Vong et al. decided to take a more naturalistic approach. They collected 61 h of video footage of a toddler wearing a head-mounted camera as they went about
-
The eyes have it Nat. Neurosci. (IF 25.0) Pub Date : 2024-03-07 Leonie Welberg
Many social species use eye contact to guide social behaviors. To study how visual cues shape social decision making, Franch et al. wirelessly recorded eye movements and activity in the visual and prefrontal cortices in two pairs of freely moving macaque monkeys. To retrieve food rewards, paired monkeys — who could see each other through a transparent screen — each had to press and hold a button and
-
Slowing human neurons Nat. Neurosci. (IF 25.0) Pub Date : 2024-03-07 Shari Wiseman
Human neurodevelopment is slower than that of other mammalian species, and this timescale appears to be intrinsic to human neural cells. However, not much is known about the mechanisms that govern this maturational timing. In a recent paper in Nature, Ciceri et al. developed a human pluripotent stem cell culture protocol that synchronously generates a uniform population of cortical neurons. The authors
-
Population coding of strategic variables during foraging in freely moving macaques Nat. Neurosci. (IF 25.0) Pub Date : 2024-03-05 Neda Shahidi, Melissa Franch, Arun Parajuli, Paul Schrater, Anthony Wright, Xaq Pitkow, Valentin Dragoi
-
The silence of the reactive astrocytes Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-29 Francesco Limone, Shane Liddelow
-
PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-29 Carmelo Milioto, Mireia Carcolé, Ashling Giblin, Rachel Coneys, Olivia Attrebi, Mhoriam Ahmed, Samuel S. Harris, Byung Il Lee, Mengke Yang, Robert A. Ellingford, Raja S. Nirujogi, Daniel Biggs, Sally Salomonsson, Matteo Zanovello, Paula de Oliveira, Eszter Katona, Idoia Glaria, Alla Mikheenko, Bethany Geary, Evan Udine, Deniz Vaizoglu, Sharifah Anoar, Khrisha Jotangiya, Gerard Crowley, Demelza M. Smeeth
-
Mapping dysfunctional circuits in the frontal cortex using deep brain stimulation Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-22 Barbara Hollunder, Jill L. Ostrem, Ilkem Aysu Sahin, Nanditha Rajamani, Simón Oxenford, Konstantin Butenko, Clemens Neudorfer, Pablo Reinhardt, Patricia Zvarova, Mircea Polosan, Harith Akram, Matteo Vissani, Chencheng Zhang, Bomin Sun, Pavel Navratil, Martin M. Reich, Jens Volkmann, Fang-Cheng Yeh, Juan Carlos Baldermann, Till A. Dembek, Veerle Visser-Vandewalle, Eduardo Joaquim Lopes Alho, Paulo Roberto
-
Dopamine projections to the basolateral amygdala drive the encoding of identity-specific reward memories Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-23 Ana C. Sias, Yousif Jafar, Caitlin M. Goodpaster, Kathia Ramírez-Armenta, Tyler M. Wrenn, Nicholas K. Griffin, Keshav Patel, Alexander C. Lamparelli, Melissa J. Sharpe, Kate M. Wassum
-
Mapping the dysfunctome provides an avenue for targeted brain circuit therapy Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-22
-
Leaky blood–brain barrier in long-COVID-associated brain fog Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-22
-
Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-22 Chris Greene, Ruairi Connolly, Declan Brennan, Aoife Laffan, Eoin O’Keeffe, Lilia Zaporojan, Jeffrey O’Callaghan, Bennett Thomson, Emma Connolly, Ruth Argue, Ignacio Martin-Loeches, Aideen Long, Cliona Ni Cheallaigh, Niall Conlon, Colin P. Doherty, Matthew Campbell
-
A phenotypic screening platform for identifying chemical modulators of astrocyte reactivity Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-20 Benjamin L. L. Clayton, James D. Kristell, Kevin C. Allan, Erin F. Cohn, Molly Karl, Andrew D. Jerome, Eric Garrison, Yuka Maeno-Hikichi, Annalise M. Sturno, Alexis Kerr, H. Elizabeth Shick, Jesse A. Sepeda, Eric C. Freundt, Andrew R. Sas, Benjamin M. Segal, Robert H. Miller, Paul J. Tesar
-
Ripple-locked coactivity of stimulus-specific neurons and human associative memory Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-16 Lukas Kunz, Bernhard P. Staresina, Peter C. Reinacher, Armin Brandt, Tim A. Guth, Andreas Schulze-Bonhage, Joshua Jacobs
-
Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19 Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-16 Josefine Radke, Jenny Meinhardt, Tom Aschman, Robert Lorenz Chua, Vadim Farztdinov, Sören Lukassen, Foo Wei Ten, Ekaterina Friebel, Naveed Ishaque, Jonas Franz, Valerie Helena Huhle, Ronja Mothes, Kristin Peters, Carolina Thomas, Shirin Schneeberger, Elisa Schumann, Leona Kawelke, Julia Jünger, Viktor Horst, Simon Streit, Regina von Manitius, Péter Körtvélyessy, Stefan Vielhaber, Dirk Reinhold, Anja
-
Hunger guides immunity to friend versus foe Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-15 Noga Or-Geva, Lawrence Steinman
-
Glial lipid droplets resolve ROS during sleep Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-15 Lindsey D. Goodman, Matthew J. Moulton, Hugo J. Bellen
-
A neuron–glia lipid metabolic cycle couples daily sleep to mitochondrial homeostasis Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-15 Paula R. Haynes, Elana S. Pyfrom, Yongjun Li, Carly Stein, Vishnu Anand Cuddapah, Jack A. Jacobs, Zhifeng Yue, Amita Sehgal
-
A unifying theory explains seemingly contradictory biases in perceptual estimation Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-15 Michael Hahn, Xue-Xin Wei
-
Anterior cingulate learns reward distribution Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-13 Tao Hong, William R. Stauffer
-
In conversation with Nancy Ip Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-13 Shari Wiseman
As Nature Neuroscience celebrates its 25th anniversary, we are having conversations with both established leaders in the field and those earlier in their careers to discuss how the field has evolved and where it is heading. This month we are talking to Nancy Ip, Morningside Professor of Life Science and president of the Hong Kong University of Science and Technology. We discussed her path from academia
-
A molecularly defined amygdala-independent tetra-synaptic forebrain-to-hindbrain pathway for odor-driven innate fear and anxiety Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-12 Hao Wang, Qin Wang, Liuzhe Cui, Xiaoyang Feng, Ping Dong, Liheng Tan, Lin Lin, Hong Lian, Shuxia Cao, Huiqian Huang, Peng Cao, Xiao-Ming Li
-
Independent inhibitory control mechanisms for aggressive motivation and action Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-12 Tomohito Minakuchi, Eartha Mae Guthman, Preeta Acharya, Justin Hinson, Weston Fleming, Ilana B. Witten, Stefan N. Oline, Annegret L. Falkner
-
Basal ganglia–spinal cord pathway that commands locomotor gait asymmetries in mice Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-12 Jared M. Cregg, Simrandeep K. Sidhu, Roberto Leiras, Ole Kiehn
-
Depression genetics goes global Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-07 Shari Wiseman
Substantial challenges for genome-wide association studies (GWAS) of major depression (as well as other psychiatric conditions) include the heterogeneity of the disorder, its degree of polygenicity and the over-representation of European ancestry among study participants. To improve upon previous efforts, a recent paper in Nature Genetics performed a GWAS meta-analysis of data from 21 cohorts that
-
Ibogaine therapy in TBI Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-07 Leonie Welberg
Traumatic brain injury (TBI) in military combat veterans is associated not only with cognitive impairments and reduced daily functioning but also with posttraumatic stress disorder (PTSD), depression and anxiety. Because regular treatments for these conditions seem to have limited efficacy, some veterans with TBI have started to explore the psychedelic ibogaine as a potential treatment. A paper published
-
Cerebellar organoids get active Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-07 Rebecca Wright
There is a pressing need to develop human cell-based models of the cerebellum, as mouse models lack human-specific features and do not fully recapitulate disease phenotypes. Using a cerebellar induction strategy based on in vivo developmental signaling molecules, Atamian et al. were able to generate 3D human organoids that reflected the major cell-type composition of the developing cerebellum, including
-
Local synaptic inhibition mediates cerebellar granule cell pattern separation and enables learned sensorimotor associations Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-06 Elizabeth A. Fleming, Greg D. Field, Michael R. Tadross, Court Hull
-
Dopamine transients follow a striatal gradient of reward time horizons Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-06 Ali Mohebi, Wei Wei, Lilian Pelattini, Kyoungjun Kim, Joshua D. Berke
-
Triple dissociation of visual, auditory and motor processing in mouse primary visual cortex Nat. Neurosci. (IF 25.0) Pub Date : 2024-02-02 Matthijs N. Oude Lohuis, Pietro Marchesi, Umberto Olcese, Cyriel M. A. Pennartz
-
Cerebellar projections to the substantia nigra modulate basal ganglia dopamine levels Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-31
-
Striatal dopamine signals reflect perceived cue–action–outcome associations in mice Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-30 Tobias W. Bernklau, Beatrice Righetti, Leonie S. Mehrke, Simon N. Jacob
-
Temporal scaling of motor cortical dynamics reveals hierarchical control of vocal production Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-30 Arkarup Banerjee, Feng Chen, Shaul Druckmann, Michael A. Long
-
Somatosensory cortex and central amygdala regulate neuropathic pain-mediated peripheral immune response via vagal projections to the spleen Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-30 Xia Zhu, Ji-Ye Huang, Wan-Ying Dong, Hao-Di Tang, Si Xu, Qielan Wu, Huimin Zhang, Ping-Kai Cheng, Yuxin Jin, Meng-Yu Zhu, Wan Zhao, Yu Mao, Haitao Wang, Yan Zhang, Hao Wang, Wenjuan Tao, Yanghua Tian, Li Bai, Zhi Zhang
-
The cerebellum directly modulates the substantia nigra dopaminergic activity Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-25 Samantha Washburn, Maritza Oñate, Junichi Yoshida, Jorge Vera, Ramakrishnan Bhuvanasundaram, Leila Khatami, Farzan Nadim, Kamran Khodakhah
-
Lateral entorhinal cortex subpopulations represent experiential epochs surrounding reward Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-25 John B. Issa, Brad A. Radvansky, Feng Xuan, Daniel A. Dombeck
-
Oligodendroglial metabolic support of myelinated axons driven by K+ dynamics Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-24
-
Oligodendrocyte–axon metabolic coupling is mediated by extracellular K+ and maintains axonal health Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-24 Zoe J. Looser, Zainab Faik, Luca Ravotto, Henri S. Zanker, Ramona B. Jung, Hauke B. Werner, Torben Ruhwedel, Wiebke Möbius, Dwight E. Bergles, L. Felipe Barros, Klaus-Armin Nave, Bruno Weber, Aiman S. Saab
-
Single-cell transcriptomics reveals that glial cells integrate homeostatic and circadian processes to drive sleep–wake cycles Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-23 Joana Dopp, Antonio Ortega, Kristofer Davie, Suresh Poovathingal, El-Sayed Baz, Sha Liu
-
Dynamic and selective engrams emerge with memory consolidation Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-19 Douglas Feitosa Tomé, Ying Zhang, Tomomi Aida, Olivia Mosto, Yifeng Lu, Mandy Chen, Sadra Sadeh, Dheeraj S. Roy, Claudia Clopath
-
A ubiquitous spectrolaminar motif of local field potential power across the primate cortex Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-18 Diego Mendoza-Halliday, Alex James Major, Noah Lee, Maxwell J. Lichtenfeld, Brock Carlson, Blake Mitchell, Patrick D. Meng, Yihan (Sophy) Xiong, Jacob A. Westerberg, Xiaoxuan Jia, Kevin D. Johnston, Janahan Selvanayagam, Stefan Everling, Alexander Maier, Robert Desimone, Earl K. Miller, André M. Bastos
-
Microglia regulate sleep through calcium-dependent modulation of norepinephrine transmission Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-18 Chenyan Ma, Bing Li, Daniel Silverman, Xinlu Ding, Anan Li, Chi Xiao, Ganghua Huang, Kurtresha Worden, Sandra Muroy, Wei Chen, Zhengchao Xu, Chak Foon Tso, Yixuan Huang, Yufan Zhang, Qingming Luo, Kaoru Saijo, Yang Dan
-
The developmental timing of spinal touch processing alterations predicts behavioral changes in genetic mouse models of autism spectrum disorders Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-17 Aniqa Tasnim, Ilayda Alkislar, Richard Hakim, Josef Turecek, Amira Abdelaziz, Lauren L. Orefice, David D. Ginty
-
Synapses shape oligodendrocyte precursor cell development and predict myelination location Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-16
-
Synaptic input and Ca2+ activity in zebrafish oligodendrocyte precursor cells contribute to myelin sheath formation Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-12 Jiaxing Li, Tania G. Miramontes, Tim Czopka, Kelly R. Monk
-
Dopamine-independent effect of rewards on choices through hidden-state inference Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-12 Marta Blanco-Pozo, Thomas Akam, Mark E. Walton
-
State and rate-of-change encoding in parallel mesoaccumbal dopamine pathways Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-11 Johannes W. de Jong, Yilan Liang, Jeroen P. H. Verharen, Kurt M. Fraser, Stephan Lammel
-
Long-term labeling and imaging of synaptically connected neuronal networks in vivo using double-deletion-mutant rabies viruses Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-11 Lei Jin, Heather A. Sullivan, Mulangma Zhu, Thomas K. Lavin, Makoto Matsuyama, Xin Fu, Nicholas E. Lea, Ran Xu, YuanYuan Hou, Luca Rutigliani, Maxwell Pruner, Kelsey R. Babcock, Jacque Pak Kan Ip, Ming Hu, Tanya L. Daigle, Hongkui Zeng, Mriganka Sur, Guoping Feng, Ian R. Wickersham
-
Distributional reinforcement learning in prefrontal cortex Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-10 Timothy H. Muller, James L. Butler, Sebastijan Veselic, Bruno Miranda, Joni D. Wallis, Peter Dayan, Timothy E. J. Behrens, Zeb Kurth-Nelson, Steven W. Kennerley
-
Women’s neuroplasticity during gestation, childbirth and postpartum Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-05 María Paternina-Die, Magdalena Martínez-García, Daniel Martín de Blas, Inés Noguero, Camila Servin-Barthet, Clara Pretus, Anna Soler, Gonzalo López-Montoya, Manuel Desco, Susana Carmona
-
Fasting-activated ventrolateral medulla neurons regulate T cell homing and suppress autoimmune disease in mice Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-05 Liang Wang, Mingxiu Cheng, Yuchen Wang, Jing Chen, Famin Xie, Li-Hao Huang, Cheng Zhan
-
Sleep restores an optimal computational regime in cortical networks Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-05 Yifan Xu, Aidan Schneider, Ralf Wessel, Keith B. Hengen
-
Latent neural population dynamics underlying breathing, opioid-induced respiratory depression and gasping Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-05 Nicholas Edward Bush, Jan-Marino Ramirez
-
Sensory and behavioral modulation of thalamic head-direction cells Nat. Neurosci. (IF 25.0) Pub Date : 2024-01-04 Eduardo Blanco-Hernández, Giuseppe Balsamo, Patricia Preston-Ferrer, Andrea Burgalossi