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  • Extended adjuvant intermittent letrozole versus continuous letrozole in postmenopausal women with breast cancer (SOLE): a multicentre, open-label, randomised, phase 3 trial
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-17
    Marco Colleoni, Weixiu Luo, Per Karlsson, Jacquie Chirgwin, Stefan Aebi, Guy Jerusalem, Patrick Neven, Erika Hitre, Marie-Pascale Graas, Edda Simoncini, Claus Kamby, Alastair Thompson, Sibylle Loibl, Joaquín Gavilá, Katsumasa Kuroi, Christian Marth, Bettina Müller, Seamus O'Reilly, Vincenzo Di Lauro, Andrea Gombos, Thomas Ruhstaller, Harold Burstein, Karin Ribi, Jürg Bernhard, Giuseppe Viale, Rudolf Maibach, Manuela Rabaglio-Poretti, Richard D Gelber, Alan S Coates, Angelo Di Leo, Meredith M Regan, Aron Goldhirsch, An Vandebroek, Martine Berliere, Carine Mitine, Peter Vuylsteke, Marleen Borms, Randal D'Hondt, Philippe Glorieux, Jeroen Mebis, Didier Verhoeven, Michael Coibion, Frederic Forget, Lionel Duck, Didier Verhoeven, Wim Wyendaele, Annelore Barbeaux, Jean-Paul Salmon, Patrick Berteloot, Joanna Vermeij, Vincent Richard, Saverio Cinieri, Lorenzo Gianni, Mario Clerico, Graziella Pinotti, Antonio Bernardo, Leo Biganzoli, Alessandra Gennari, Claudio Graiff, Dino Amadori, Rodolfo Passalacqua, John Forbes, Prudence Francis, Serene Foo, Frances Boyle, Andrew Redfern, Andre van der Westhuizen, Craig Lewis, Sharad Sharma, Philip Beale, Ian Byard, Stephen Begbie, Frank Sardelic, Ehtesham Abdi, David Clark, Aaron Chindewere, Stephen Della-Fiorentina, Ray Asghari, Mohammed Islam, Lee Na Teo, Shane White, Linda Gilbert, Katherine Gardner, Catarina Uhlmann, Daniel Rauch, Meinrad Mannhart, Katharina Buser, Konstantin Dedes, Andreas Mueller, Christoph Rageth, Stephanie Von Orelli, Hans Joerg Senn, Olivia Pagani, Augusto Pedrazzini, Christoph Rochlitz, Alexandre Bodmer, Sandro Anchisi, Khalil Zaman, Roger von Moos, Daniel Betticher, Elena Kralidas, Razven Popescu, Mathias Fehr, Per Nyman, Anja Jungquist, Chaido Chamalidou, Theodoros Foukakis, Charlotta Dabrosin, Antonis Valachis, Istvan Lang, Zsuzsanna Kahan, Javier Retamales, Ulloa Roberto Torres, Marcela Fritis, Sebastian Sole, Soledad Torres, Jaime Letzkus, Paula Escobar, Ines Vigneaux, Jorge Arancibia, Juana Bernardita Cardemil, Patricio Huidobro, Henry Gomez, Julie Wetter, Daniel Vorobiof, Gary McMichael, Justus Apffelstaedt, Igor Vorotnikov, Joel Schwartz, Thomas Openshaw, Herve Bonnefoi, Jean-Philippe Jacquin, Natalie Bonichon-Lamichhane, Simona Borstner, Ashwini Budrukkar, Marianne Ewertz, Oscar Zambrano Quispe, Peter Michael Vestlev, Hella Danø, Ditte Nielsen, Erik Jakobsen, Inger Hoejris, Jurij Antonovic Bogovic, Britta Bjerregaard Jensen, Knud Aage Møller, Eric Lars Stenbygaard, Ravi Sharma, Carolyn Bedi, Maria Bews-Hair, Glyn Neades, Mike McKirdy, Matthew Barber, Abdulla Alhasso, Diana Ritchie, Judith Fraser, Lucy Scott, Frances Yuille, Alison Lannigan, Dermot Murphy, Mike Shere, Christian Jackisch, Oliver Tomé, Susanne Steer, Doris Augustin, Kristina Lübbe, Christian Jackisch, Heike Köcker-Korus, Jörg-Uwe Deuker, Andrea Stefek, Marianne Just, Uwe Rhein, Christina Bechtner, Dirk-Toralf Baerens, Iris Schrader, Eva-Maria Grischke, Ralf Lorenz, Wolfgang Dietz, Jörg Thomalla, Jörg Schilling, Andreas Rempen, Heiko Graf, Gabriele Doering, Steffi Busch, Georg Heinrich, Hans Tesch, Christoph Uleer, Petra Krabisch, Siegfried Rösel, Christian Kurbacher, Horst Ostertag, Klaus-M Josten, Carsten Hielscher, Isolde Gröll, Ute Marie Mattner, Anita Prechtl, Tilmann Lantzsch, Eva Ciruelos, Isabel Garau, Meritxell Bellet, Miguel Angel Climent, Rafael López, Juan Antonio Virizuela, Begoña Bermejo, Noelia Martinez Janez, Kepa Amillano, Raúl Márquez, Joan Dorca, Maria Jose Godes, Santiago Gonzalez, Shinji Ohno, Tomoyuki Aruga, Daisuke Yotsumoto, Yutaka Yamamoto, Tomohiko Aihara, Takashi Morimoto, Hiroko Bando, Norikazu Masuda, Masakazu Toi, Kenjiro Aogi, Nobuaki Sato, Morihito Okada, Masato Takahashi, Eriko Tokunaga, Hiroji Iwata, Takashi Fujita, Michael Fridrik, Gunda Pristauz, Claudia Hackl, Christian Singer, Victor Wette, Michael Gnant, Josef Thaler, Richard Greil, Burghard Abendstein, Dietmar Heck, Diether Manfreda, Paul Sevelda, Irene Thiel, Frank Tuttlies, Herbert Stöger, Walter Neunteufel, John Crown, John Kennedy, Arnold Hill, John McCaffrey, Conleth Murphy, Linda Coate, Maccon Keane, Michael Martin, Miriam O'Connor, Karen Duffy, Barbara Ruepp, Martine Piccart, Dimitrios Zardavas
    更新日期:2017-11-19
  • Complexity of intermittent letrozole adjuvant therapy
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-17
    Rowan T Chlebowski, Kathy Pan
    更新日期:2017-11-19
  • Defining precision medicine
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-16
    Talha Khan Burki
    更新日期:2017-11-17
  • Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-13
    Miguel Martin, Frankie A Holmes, Bent Ejlertsen, Suzette Delaloge, Beverly Moy, Hiroji Iwata, Gunter von Minckwitz, Stephen K L Chia, Janine Mansi, Carlos H Barrios, Michael Gnant, Zorica Tomašević, Neelima Denduluri, Robert Šeparović, Erhan Gokmen, Anna Bashford, Manuel Ruiz Borrego, Sung-Bae Kim, Erik Hugger Jakobsen, Audrone Ciceniene, Kenichi Inoue, Friedrich Overkamp, Joan B Heijns, Anne C Armstrong, John S Link, Anil Abraham Joy, Richard Bryce, Alvin Wong, Susan Moran, Bin Yao, Feng Xu, Alan Auerbach, Marc Buyse, Arlene Chan, Vernon Harvey, Rudolf Tomek, Nicholas J. Robert, Ira Gore, John W. Smith, Norikazu Masuda, S. Di Sean Kendall, William Graydon Harker, Katarina Petrakova, Angel Guerrero Zotano, Amparo Ruiz Simon, Zora Neskovic Konstantinovic, Nicholas O. Iannotti, Pierfrancesco Tassone, Gladys I. Rodriguez, Noelia Jáñez Martinez, Carmen Crespo Massieu, Snezana Smickoska, Isil Somali, Ugur Yilmaz, Mirta Garcia Alonso, Adolfo Murias Rosales, Soeren Cold, Ann Soegaard Knoop, Debra Patt, Beth A. Hellerstedt, Serafin Morales Murillo, Ingrid A. Mayer, Julie Ann Means-Powell, Rina Hui, Francis M. Senecal, Richard Hendry De Boer, Zhenzhou Shen, Adam Andrzej Luczak, Joanna W.Y. Chui, Janice Wing-hang Tsang, Istvan Lang, Yoshiaki Rai, Yasuo Hozumi, Albert J. Ten Tije, Manish Bhandari, Cynthia R.C. Osborne, Shoichiro Ohtani, Kenji Higaki, Kenichi Watanabe, Kazunori Taguchi, Masato Takahashi, Sladjana Filipovic, Vincent L. Hansen, Vijayarama Phooshkooru Rao, Manish Gupta, Petar Petrov, Bruno Coudert, Zeljko Vojnovic, Zsofia Polya, Toshiko Miyaki, Naohito Yamamoto, Stephen Brincat, Krzysztof Lesniewski-Kmak, Ewa Chmielowska, Ruemu E. Birhiray, Marc L. Citron, Steven William Papish, William R. Berry, Sven Tyge Langkjer, José Angel Garcia Sáenz, Ana Maria Arance, Noa Efrat, Tomasz Sarosiek, Lukasz Grzeda, Yvonne Manalo, Julie C. Smith, Irfan Vaziri, Tabitha Healey, Yasmin Rahim, Cynthia Luk, Brian Dingle, Sandra Franco, Peter Grundtvig Sorensen, Anjana Anand, Sarah Khan, George Fountzilas, Kenjiro Aogi, Satoru Shimizu, Milada Mikulova, Stanislav Spanik, Robert A. Somer, Patrick J. Flynn, Jermaine Coward, Paul Mainwaring, Guy Jerusalem, Carine Segura-Ojezzar, Christelle Levy, Thierry Delozier, David Khayat, Robert E. Coleman, Martin J. Rolles, Robert Maisano, Mario Nardi, Yoshinori Ito, Perran Fulden Yumuk, Gul Basaran, Nazim Serdar Turhal, Mary J. Wilkinson, Nathan B. Green, Algis P. Sidrys, Sigrun Hallmeyer, Douglas J. Testori, Srikala Sridhar, Jose Chang, Qiang Sun, Carlos Jara-Sanchez, Xabier Rubio, Maria Lomas Garrido, Juan Rafael De La Haba Rodriguez, Antonia Perello Martorell, Antoni Avelia Mestre, Julio Rifa Ferrer, Sonia del Barco Berron, Zsuzsanna Nagy, Maki Tanaka, Young-Hyuck Im, Robert R. Carroll, Laura C. Dickerson, Joseph R. Mace, Ragene Rivera, Leonard M. Klein, Robert Ruxer, Sharon T. Wilks, Dusan Kotasek, Vasil Popov, Violina Taskova, Violetka Marinova-Venkova, Constanta Timcheva, Christine Desbiens, Jean-Pierre Ayoub, Debjani Grenier, Norbert Marschner, Hans Tesch, Hans-Joachim Lueck, Jan Janssen, Ingo Schwaner, Stine Wahlstrom, Eva Harder Brix, Susanne Vallentin, Dan Kristensen, Anna Andreeva, Vesna Glavicic, Isabel Calvo Plaza, Antonio Anton Torres, Corinne Veyret, Jean-Pierre Bergerat, Emmanuelle Bourbouloux, Wendy Ann Ella, Hafiz Algurafi, Anne Robinson, Seung Jin Kim, Tetsuya Taguchi, Elona Juozaityte, Stanley Madretsma, Sandra Radema, Malgorzata Czerniawska-Meier, Wojciech Rogowski, Maria Wagnerova, Donald A. Richards, Elizabeth Tan-Chiu, Asskikis Vasileios, Charles Arthur Henderson, Viran Roger Holden, Xiaojia Wang, Zhongsheng Tong, Junlan Yang, Manuel Enrique Gonzalez, Mahdi Rezai, John Hackmann, Eduardo Martinez de Dueñas, Begoña Bermejo de las Heras, Louis Marie Dourthe, Dorothee Chocteau-Bouju, Philippe Bougnoux, Stylianos Kakolyris, Haralabos Kalofonos, Dimitrios Pectasidis, Ting Ying Ng, Gabor Pajkos, Eva Ezer Somogyine, Giuseppe Tonini, Dario Giuffrida, Shintaro Takao, Makoto Ishitobi, Hideo Inaji, Yutaka Tokuda, Katarzyna Wozniak, Dan Lungulescu, Yen-Shen Lu, King-Jen Chang, Julian Hill, Christopher Charles Croot, Albert Dekker, Neil D. Belman, Miguel Conde, Richard A. Michaelson, Kathleen Kemmer, Stephen Chui, Shiuh-Wen Luoh, Kenneth Nahum, Andrew R. Greenspan, Joni C. Nichols, Carlos A. Encarnacion, Thomas M.J. Niederman, Theresa Lee, Roland Alexander, Robert Gordon, Antoanet Tomova, Daniel Rauch, Razvan Andrei Popescu, Gustavo Adolfo Rojas, Jaroslav Vanasek, Tanja Neunhoeffer, Jana Barinoff, Gerd Graffunder, Abenhardt Wolfgang, Peter Bojko, Bernhard Heinrich, Albert von der Assen, Bogovic Jurij Antonovic, Lene Adrian, Manuel Ramos Vazquez, Santiago Gonzalez Santiago, Veronique Dieras, Jill Mercia Bishop, Timothy John Perren, Ioannis Varthalitis, Dimitris Mavroudis, Vassilis Georgoulias, Louis W.C. Chow, Chung Cheung Thomas Yau, Raymond Hin-Suen Liang, Béla Pikó, Agnes Wéber, Bella Kaufman, Karen Drumea, Francesco Nuzzo, Andrea De Matteis, Francesco Nuzzo, Giacomo Carteni, Eriko Tokunaga, Mayumi Ishida, Shinji Ohno, Nobuaki Sato, Katsumasa Kuroi, Reiki Nishimura, Junichiro Watanabe, Yoon Ji Choi, Kyong Hwa Park, Marek Wojtukiewicz, Jacek Jassem, Niklas Loman, Sercan Askoy, Mustafa Kadri Altundag, Pinar Saip, Muhammad Amjad Ali, James Lloyd Wade III, Amy Jo Chien, Debra Brandt, Yelena Novik, Chirag Jani, Robert L. Rice, Yousuf A. R Gaffar, Mark R. Keaton, Rajesh Bajaj, Gretchen Kimmick, David Campbell, Richard Hendry De Boer, Theodore Turnquest, Sideras Lucas, Pierre Dube, Binghe Xu, Joerg Schilling, Klaus Apel, Peter Grundtvig Sorensen, Peter Michael Vestlev, Brita Bjerregaard Jensen, Vera Haahr, Alvaro Rodriguez Lescure, Begona Grana Suarez, Cristina Saura Manich, Jean-Philippe Jacquin, Ahmed Samreen, Ion Boiangiu, Magdolna Dank, Cristina Falci, Antonio Jirillo, Saverio Cinieri, Takayuki Ueno, Fumiaki Sato, Hiroyasu Yamashiro, Tomoharu Sugie, Keun Seok Lee, Jung Sil Ro, In Hae Park, Anita Zarina Bustam, Malgorzata Suszko-Kazarnowicz, Artur Piktel, Krzysztof Krzemieniecki, Polizenia Georgeta Iorga, Yoon Sim Yap, Marian Kakalejcik, Alper Sevinc, Mustafa Ozguroglu, Shin-Cheh Chen, Richard H. Greenberg, Allan Daniel Eisemann, Robert Droder, M. Rashid Abbasi, Marina Vaysburd, Humberto Jose Caldera, Barbara Bacsik Haley, Erwin Robin, Roger C. Inhorn, David Hufnagel, Peter D. Kenyon, Ellen Spremulli, Paula Silverman, Sharad Jain, Robert Weigand, Jeroen Mebis, Tatyana Koynova, Bernard Lesperance, Jana Prausova, Claus-Henning Kohne, Andreas Schneeweiss, Christian Jackisch, Stefan Fuxius, Ricardo Cubedo Cervera, Ander Urruticoechea Ribate, Sonia Pernas Simon, Jose Valero Gallego, Angels Arcusa Lanza, Maria del Pilar Alvarez, Jesus Florian Gerico, Laurent Cany, Justin Stebbing, Dejan Labudovic, Damir Gugic, Damir Vrbanec, Fausto Roila, Sandro Barni, Paolo Bidoli, Hirofumi Mukai, Vanessa Bermudez, Alexandru Eniu, Barry C. Mirtsching, Emad Ibrahim, Joan Trey, Paul Francis Hergenroeder, Aftab Mahmood, Anneliese Gonzalez, Edward H. Kaplan, Stacy Ban, Dhimant Patel, Billy Clowney, Karen Hoelzer, Garry H. Schwartz, Mohamed Salkeni, Jame Abraham, Sunil Narula, Khaled Jabboury, Robert Scott Mocharnuk, Richard H. McDonough, David H. Sikes, Ronald H. Kawanchi, Larry Schlabach, Samuel Spence McCachren, Thomas M. Cosgriff, Luke Dreisbach, Angela DeMichele, Lawrence Pawl, Jennifer Lucas, Lowell C. Shinn, Nabiel Alkhouri, Manish Monga, Deborah L. Lindquist, Thomas C. Anderson, Humera Khurshid, Sabrina Witherby, Nicholette Erickson, Ann Traynor, Ron Bose, Timothy J. Pluard, Michael C. Jones, Sucharu Prakash, Fabio Volterra, Gerardo Capo, Lawrence E. Flaherty, Elaina Gartner, Said Baidas, Ian Okazaki, Bichlien Nguyen, Thomas Rakowski, Ira Oliff, Joseph W. Leach, Daniel Anderson, Kendra Kubiak, Michaela Tsai, Philippe Vroman, Ines Deleu, Willem Lybaert, Marleen Borms, Felix Couture, Jonathan J. Wilson, Gordon Hunt, David R. Holland, Walter Mingrone, Shusen Wang, Donggeng Liu, Zefei Jiang, Vera Benesova, Martin Smakal, Petra Garnolova, Anne-Sophie Vesper, Monika Neumann, Wolfgang Janni, Cornelia Liedtke, Dorothea Fischer, Eva-Maria Grischke, Dietmar Seeger, Volker Moebus, Anita Prechtl, Juan Carlos Camara Toral, Alfonso Sanchez Munoz, Sonia Gonzalez Jimenez, Javier Cassinello Espinosa, Beatriz Cirauqui, Mireia Margeli Vila, Norberto Batista Lopez, Jose Ignacio Chacon Lopez-Muniz, Miguel Angel de la Cruz Mora, Audrey Mailliez, Laurence Vanlemmens, Damien Pouessel, Marc Espie, John Conibear, Rebecca Roylance, Adrian Harnett, David Geffen, Enzo Maria Ruggeri, Teresa Gamucci, Cees J. Van Groeningen, Renata Banas, Niklas Loman, Necati Alkis, Ming-Feng Hou, Amy K. Krie, Nandagopal S. Vrindavanam, Orion M. Howard, Dennis Citrin, Mark S. Morginstin, Ajit Desai, Ines J. Sanchez, David Allen Nixon, Patrick G. Beatty, Kathryn Edmiston, Marilyn McLaughlin, Jonathan D. Eneman, Cynthia A. Lynch, Edward O'Brien, Justin A. Call, Keith S. Lanier, Alison Conlin, Donald J. Brooks, Kristi McIntyre, Marc A. Saltzman, Michael J. Castine, Gregory L. Ortega, Young M. Choi, Craig H. Reynolds, Frankie Ann Brescia, Rita Kramer, Aimee D. Kohn, John P. Micha, Jessica M. Rhee, Satish Shah, David A. Riseberg, William Kevin Patterson, Jean-Paul Salmon, Chantal Andre, Alain Bols, Randal D'hondt, Sylvie Luce, Claire Nouwynck, Gino Pelgrims, Vincent Richard, Johan Verschuere, Kurt Geldhof, Clemens Caspar, Rongcheng Luo, Otakar Bednarik, Kathrin Schwedler, Marcus Schmidt, Romy Neumeister, Joachim Bischoff, Brigitte Rack, Roland Repp, Stefan Fries, Ralf Adrion, Volker Schulz, Peter Klare, Mahmoud Danei, Dirk Ossenbuhl, Jakob Manfred Kusche, Frank Griesinger, Jose Manuel Baena Canada, Purificacion Martinez del Prado, David Machover, Didier Mayeur, Nathalie Trufflandier, Valerie Delecroix, Mireille Mousseau, Marie-Ange Mouret-Reynier, Jean-Marc Nabholtz, Anula D. Chetiyawardana, Christos Papandreou, Lajos Hornyak, Zsolt Faluhelyi, Erzsebet Simo, Mario Di Palma, Francesco Cognetti, Gabriella Gorzegno, Luigi Dogliotti, Cesare Gridelli, Alfredo Falcone, Hector Soto Parra, Calogero Buscarino, Seock-Ah Im, Benito Sanchez Llamas, Wouter Dercksen, Franciscus Erdkamp, Jan B. Ruit, Hans Braun, Joanneke E.A. Portielje, Aydin Ciltas, Suleyman Buyukberber, Mustafa Benekli, Andrew J. Zahalsky, Rebecca Jaslow, Gary W. Thomas, Archana Maini, Israel Wiznitzer, Ali Khojasteh, Manuel Francisco Gonzalez, Lynn R. Kong, Aruna Padmanabhan, William A. Conkright, Sandra M. Swain, Douglas E. Faig, Kirti Jain, Ronald H. Yanagihara, Yvonne Ottaviano, Andrew Delmas, Heather A. Steele, Gordon K. Rainey, Penelope J. Harris, Jason K. Burris, Erik J. Rupard, Esther Tan, Pat W. Whitworth, Abby R. Bova, Ian C. Anderson, Mihran Shirinian, Caesar Tin-u, Timothy J. O'Rourke, Michael S. Roberts, Michael Francisco, A. Scott Pierson, Peter D. Byeff, Peter A. Kovach, John R. Caton, Mark Urban Rarick, William G. Schimidt, Alison T. Stopeck, Rachel Swart, Maria Regina Carrillo Flores, Carlos A. Alemany, Brennely Lozada, Paul L. Weinstein, Wei Wang, Michael Porubcin, David M. Ellison, George F. Geils, Edgardo Rivera, Mahmoud Charif
    更新日期:2017-11-14
  • Extended adjuvant therapy in patients with HER2-positive breast cancer: some answers, even more questions
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-13
    Mariana Chavez-MacGregor, Elizabeth A Mittendorf
    更新日期:2017-11-14
  • Incorporation of brentuximab vedotin into first-line treatment of advanced classical Hodgkin's lymphoma: final analysis of a phase 2 randomised trial by the German Hodgkin Study Group
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-10
    Dennis A Eichenauer, Annette Plütschow, Stefanie Kreissl, Martin Sökler, Johannes C Hellmuth, Julia Meissner, Stephan Mathas, Max S Topp, Karolin Behringer, Wolfram Klapper, Georg Kuhnert, Markus Dietlein, Carsten Kobe, Michael Fuchs, Volker Diehl, Andreas Engert, Peter Borchmann
    更新日期:2017-11-11
  • Brentuximab vedotin for advanced Hodgkin's lymphoma
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-10
    Michelle A Fanale
    更新日期:2017-11-11
  • Custirsen (OGX-011) combined with cabazitaxel and prednisone versus cabazitaxel and prednisone alone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel (AFFINITY): a randomised, open-label, international, phase 3 trial
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-09
    Tomasz M Beer, Sebastien J Hotte, Fred Saad, Boris Alekseev, Vsevolod Matveev, Aude Fléchon, Gwenaelle Gravis, Florence Joly, Kim N Chi, Zafar Malik, Brent Blumenstein, Patricia S Stewart, Cindy A Jacobs, Karim Fizazi
    更新日期:2017-11-10
  • Participant selection for lung cancer screening by risk modelling (the Pan-Canadian Early Detection of Lung Cancer [PanCan] study): a single-arm, prospective study
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-17
    Martin C Tammemagi, Heidi Schmidt, Simon Martel, Annette McWilliams, John R Goffin, Michael R Johnston, Garth Nicholas, Alain Tremblay, Rick Bhatia, Geoffrey Liu, Kam Soghrati, Kazuhiro Yasufuku, David M Hwang, Francis Laberge, Michel Gingras, Sergio Pasian, Christian Couture, John R Mayo, Paola V Nasute Fauerbach, Sukhinder Atkar-Khattra, Stuart J Peacock, Sonya Cressman, Diana Ionescu, John C English, Richard J Finley, John Yee, Serge Puksa, Lori Stewart, Scott Tsai, Ehsan Haider, Colm Boylan, Jean-Claude Cutz, Daria Manos, Zhaolin Xu, Glenwood D Goss, Jean M Seely, Kayvan Amjadi, Harmanjatinder S Sekhon, Paul Burrowes, Paul MacEachern, Stefan Urbanski, Don D Sin, Wan C Tan, Natasha B Leighl, Frances A Shepherd, William K Evans, Ming-Sound Tsao, Stephen Lam
    更新日期:2017-11-10
  • Safety, pharmacokinetics, and antitumour activity of trastuzumab deruxtecan (DS-8201), a HER2-targeting antibody–drug conjugate, in patients with advanced breast and gastric or gastro-oesophageal tumours: a phase 1 dose-escalation study
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-13
    Toshihiko Doi, Kohei Shitara, Yoichi Naito, Akihiko Shimomura, Yasuhiro Fujiwara, Kan Yonemori, Chikako Shimizu, Tatsunori Shimoi, Yasutoshi Kuboki, Nobuaki Matsubara, Atsuko Kitano, Takahiro Jikoh, Caleb Lee, Yoshihiko Fujisaki, Yusuke Ogitani, Antoine Yver, Kenji Tamura
    更新日期:2017-11-10
  • Extended adjuvant aromatase inhibition after sequential endocrine therapy (DATA): a randomised, phase 3 trial
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-11
    Vivianne C G Tjan-Heijnen, Irene E G van Hellemond, Petronella G M Peer, Astrid C P Swinkels, Carolien H Smorenburg, Maurice J C van der Sangen, Judith R Kroep, Hiltje De Graaf, Aafke H Honkoop, Frans L G Erdkamp, Franchette W P J van den Berkmortel, Maaike de Boer, Wilfred K de Roos, Sabine C Linn, Alexander L T Imholz, Caroline M Seynaeve, J.J.E.M. Kitzen, L.J.A. Strobbe, E.A. Kouwenhoven, T. van Dalen, A.J. van Overbeeke, J.K.S. Nuytinck, I.E. Arntz, R.J.B. Blaisse, H.B.A.C. Stockmann, P.H.A. Nijhuis, G.J. Veldhuis, W.J.B. Mastboom, J.M.G.H. van Riel, J.H. van Dam, M.O. den Boer, M.J. Agterof, M.A.J. de Roos, R.M.H. Roumen, J.J.M. van der Hoeven, A. Beeker, R. Koelemij, A. van Bochove, G.S. Madretsma, E.J.M. Siemerink, O.R. Guicherit, A.H. Vos, G.A.P. Nieuwenhuijzen, D.F.S. Kehrer, F.A.A. Valster, B.C. Tanis, T. van Voorthuizen, A.M.T. van der Velden, R.A. Hellingman, R. Vree, Q. van Rossum-Schornagel, J.M. Meerum Terwogt, W.G. van Leeuwen-Breuk, J.G. Haasjes, M.A. Davidis-van Schoonhoven, E.J.C. Vriens, M. Jagers, E.W. Muller, P.P.J.B.M. Schiphorst, C.J. van Groeningen, M.A. van Dijk, E. Janssens- van Vliet, E.E.M. Schepers, J.W.S. Merkus, N.G.J. van Diemen, R.C. van Doorn, K. Bosscha, R. den Toom, P.C. van der Velden, C.T.A.M. van Rossum, H.M. Oosterkamp, R. van Hillegersberg, B. Jas, E.E.M. Weernink, J.M.A. Ketel, J.J. Jansen, J.K. Maring, M.J.P.M. Govaert, Y.J.L. Kamm, M.M. Vleugel, S. Hovenga, J. de Boer, H. Potthoff, D.W. Sommeijer, E.J. van Dulken
    更新日期:2017-11-10
  • Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-04
    Hussein A Tawbi, Melissa Burgess, Vanessa Bolejack, Brian A Van Tine, Scott M Schuetze, James Hu, Sandra D'Angelo, Steven Attia, Richard F Riedel, Dennis A Priebat, Sujana Movva, Lara E Davis, Scott H Okuno, Damon R Reed, John Crowley, Lisa H Butterfield, Ruth Salazar, Jaime Rodriguez-Canales, Alexander J Lazar, Ignacio I Wistuba, Laurence H Baker, Robert G Maki, Denise Reinke, Shreyaskumar Patel
    更新日期:2017-11-10
  • First-line pembrolizumab in cisplatin-ineligible patients with locally advanced and unresectable or metastatic urothelial cancer (KEYNOTE-052): a multicentre, single-arm, phase 2 study
    Lancet Oncol. (IF 33.9) Pub Date : 2017-09-26
    Arjun V Balar, Daniel Castellano, Peter H O'Donnell, Petros Grivas, Jacqueline Vuky, Thomas Powles, Elizabeth R Plimack, Noah M Hahn, Ronald de Wit, Lei Pang, Mary J Savage, Rodolfo F Perini, Stephen M Keefe, Dean Bajorin, Joaquim Bellmunt
    更新日期:2017-11-10
  • Rilotumumab plus epirubicin, cisplatin, and capecitabine as first-line therapy in advanced MET-positive gastric or gastro-oesophageal junction cancer (RILOMET-1): a randomised, double-blind, placebo-controlled, phase 3 trial
    Lancet Oncol. (IF 33.9) Pub Date : 2017-09-25
    Daniel V T Catenacci, Niall C Tebbutt, Irina Davidenko, André M Murad, Salah-Eddin Al-Batran, David H Ilson, Sergei Tjulandin, Evengy Gotovkin, Boguslawa Karaszewska, Igor Bondarenko, Mohamedtaki A Tejani, Anghel A Udrea, Mustapha Tehfe, Ferdinando De Vita, Cheryl Turkington, Rui Tang, Agnes Ang, Yilong Zhang, Tien Hoang, Roger Sidhu, David Cunningham
    更新日期:2017-11-10
  • Effect of patient choice and hospital competition on service configuration and technology adoption within cancer surgery: a national, population-based study
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-03
    Ajay Aggarwal, Daniel Lewis, Malcolm Mason, Arnie Purushotham, Richard Sullivan, Jan van der Meulen
    更新日期:2017-11-10
  • Rising cancer drug costs in the USA
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-20
    Talha Khan Burki
    更新日期:2017-11-10
  • UK radiologist staffing crisis reaches critical levels
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-20
    Elizabeth Gourd
    更新日期:2017-11-10
  • Copanlisib in heavily pretreated indolent lymphoma
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-12
    Manjulika Das
    更新日期:2017-11-10
  • Oncolytic virus therapy in advanced melanoma
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-12
    Elizabeth Gourd
    更新日期:2017-11-10
  • First-line obinutuzumab for follicular lymphoma
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-12
    Holly Baker
    更新日期:2017-11-10
  • Maintenance rituximab in mantle-cell lymphoma
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-05
    Talha Khan Burki
    更新日期:2017-11-10
  • Insulin analog linked to breast cancer risk
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-05
    Elizabeth Gourd
    更新日期:2017-11-10
  • Adding radiotherapy to chemotherapy in advanced NSCLC
    Lancet Oncol. (IF 33.9) Pub Date : 2017-09-28
    Vicki Brower
    更新日期:2017-11-10
  • Inpatient palliative care during transplantation
    Lancet Oncol. (IF 33.9) Pub Date : 2017-09-28
    Ashray Gunjur
    更新日期:2017-11-10
  • Pyrotinib shows activity in metastatic breast cancer
    Lancet Oncol. (IF 33.9) Pub Date : 2017-09-21
    Elizabeth Gourd
    更新日期:2017-11-10
  • 49th SIOP Congress
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-20
    Allison Landman
    更新日期:2017-11-10
  • Adjuvant zoledronic acid to treat breast cancer: not for all
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-13
    Luís Costa, Arlindo R Ferreira
    更新日期:2017-11-10
  • Moving toward a precision medicine approach in metastatic castration-resistant prostate cancer
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-09
    Rahul Aggarwal
    更新日期:2017-11-10
  • Lung cancer screening and its continuous risk assessment
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-17
    Harry J de Koning
    更新日期:2017-11-10
  • Antibody-drug conjugates: can the payload improve activity in HER2 expressing cancers?
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-13
    Manish A Shah
    更新日期:2017-11-10
  • Extended adjuvant therapy: the role of subset analyses
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-11
    Kathleen I Pritchard
    更新日期:2017-11-10
  • PD-1 inhibition in bone sarcoma and soft-tissue sarcoma
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-04
    Olivier Mir, Charles Honoré, Julien Adam
    更新日期:2017-11-10
  • New option for cisplatin-ineligible urothelial cancer
    Lancet Oncol. (IF 33.9) Pub Date : 2017-09-26
    Robert Dreicer
    更新日期:2017-11-10
  • Continued disappointments with targeted agents in first-line therapy of advanced gastric cancers
    Lancet Oncol. (IF 33.9) Pub Date : 2017-09-25
    Daniel H Ahn, Axel Grothey
    更新日期:2017-11-10
  • Is competition bad for our health(care)? We simply don't know
    Lancet Oncol. (IF 33.9) Pub Date : 2017-10-03
    Kalipso Chalkidou
    更新日期:2017-11-10
  • Gut microbiome and immunotherapy response
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-09
    Talha Khan Burki
    更新日期:2017-11-09
  • Health-related quality-of-life results for pembrolizumab versus chemotherapy in advanced, PD-L1-positive NSCLC (KEYNOTE-024): a multicentre, international, randomised, open-label phase 3 trial
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-09
    Julie R Brahmer, Delvys Rodríguez-Abreu, Andrew G Robinson, Rina Hui, Tibor Csőszi, Andrea Fülöp, Maya Gottfried, Nir Peled, Ali Tafreshi, Sinead Cuffe, Mary O'Brien, Suman Rao, Katsuyuki Hotta, Jin Zhang, Gregory M Lubiniecki, Anne C Deitz, Reshma Rangwala, Martin Reck
    更新日期:2017-11-09
  • Quality of life: an important element of treatment value
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-09
    Massimo Di Maio
    更新日期:2017-11-09
  • Adjuvant chemotherapy with or without bevacizumab in patients with resected non-small-cell lung cancer (E1505): an open-label, multicentre, randomised, phase 3 trial
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-09
    Heather A Wakelee, Suzanne E Dahlberg, Steven M Keller, William J Tester, David R Gandara, Stephen L Graziano, Alex A Adjei, Natasha B Leighl, Seena C Aisner, Jan M Rothman, Jyoti D Patel, Mark D Sborov, Sean R McDermott, Roman Perez-Soler, Anne M Traynor, Charles Butts, Tracey Evans, Atif Shafqat, Andrew E Chapman, Samer S Kasbari, Leora Horn, Suresh S Ramalingam, Joan H Schiller
    更新日期:2017-11-09
  • Bosutinib more effective than imatinib in CML
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-09
    Elizabeth Gourd
    更新日期:2017-11-09
  • Biomarkers for subtypes of pancreatic ductal adenocarcinoma
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-09
    Priya Venkatesan
    更新日期:2017-11-09
  • Bevacizumab in adjuvant treatment of non-small-cell lung cancer
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-09
    Jared Weiss
    更新日期:2017-11-09
  • Incomplete excision of cervical precancer as a predictor of treatment failure: a systematic review and meta-analysis
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-07
    Marc Arbyn, Charles W E Redman, Freija Verdoodt, Maria Kyrgiou, Menelaos Tzafetas, Sadaf Ghaem-Maghami, Karl-Ulrich Petry, Simon Leeson, Christine Bergeron, Pekka Nieminen, Jean Gondry, Olaf Reich, Esther L Moss
    更新日期:2017-11-08
  • Questioning the value of margin status in treated cervical precancer
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-07
    Paul A Cohen
    更新日期:2017-11-08
  • Olaparib in combination with paclitaxel in patients with advanced gastric cancer who have progressed following first-line therapy (GOLD): a double-blind, randomised, placebo-controlled, phase 3 trial
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-02
    Yung-Jue Bang, Rui-Hua Xu, Keisho Chin, Keun-Wook Lee, Se Hoon Park, Sun Young Rha, Lin Shen, Shukui Qin, Nong Xu, Seock-Ah Im, Gershon Locker, Phil Rowe, Xiaojin Shi, Darren Hodgson, Yu-Zhen Liu, Narikazu Boku
    更新日期:2017-11-03
  • Missing a GOLDen opportunity in gastric cancer
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-02
    Elizabeth Smyth
    更新日期:2017-11-03
  • Thermography should not be used in breast cancer screening
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-02
    Elizabeth Gourd
    更新日期:2017-11-03
  • Possible origin of ovarian cancer in the fallopian tubes
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-02
    Priya Venkatesan
    更新日期:2017-11-03
  • Tobacco control in the UK
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-02
    Talha Khan Burki
    更新日期:2017-11-03
  • Mapping a path for cancer precision medicine
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-01
    Douglas K Price, Cindy H Chau, William D Figg
    更新日期:2017-11-01
  • Cancer in Tinsel Town
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-01
    Catherine Lucas
    更新日期:2017-11-01
  • One for sorrow, two for joy
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-01
    Kelley Swain
    更新日期:2017-11-01
  • The Purple Drug Guide
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-01
    Caroline Kinsey
    更新日期:2017-11-01
  • What Cancer Taught Me
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-01
    Victoria Denny
    更新日期:2017-11-01
  • Neoadjuvant chemotherapy in oesophageal adenocarcinoma – Authors' reply
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-01
    Derek Alderson, Matthew Nankivell, Ruth Langley, David Cunningham

    In response to the comments about the UK MRC OE05 trial,1 we acknowledge the ongoing debate about the treatment of patients with oesophageal adenocarcinoma.

    更新日期:2017-11-01
  • Neoadjuvant chemotherapy in oesophageal adenocarcinoma
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-01
    Lorenzo Fornaro, Giuseppe Aprile

    Alderson and colleagues should be congratulated for the MRC OE05 trial,1 randomly assigning almost 900 patients with locally advanced, resectable oesophageal adenocarcinoma to cisplatin and fluorouracil (CF) for two cycles, or to epirubicin, cisplatin, and capecitabine (ECX) for four cycles, followed by surgery in both groups. The trial failed to demonstrate a significant overall survival improvement with ECX (hazard ratio 0·90, 95% CI 0·77–1·05; p=0·19).

    更新日期:2017-11-01
  • Neoadjuvant chemotherapy in oesophageal adenocarcinoma
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-01
    Hanneke W M van Laarhoven, Mark I van Berge Henegouwen, Maarten C C M Hulshof

    We applaud Derek Alderson and colleagues1 for conducting the UK MRC OE05 trial. This randomised study showed that four neoadjuvant cycles of epirubicin, cisplatin, and capecitabine (ECX) did not improve survival of patients with oesophageal cancer compared with two neoadjuvant cycles of cisplatin and fluorouracil (CF).1 Thereby, this study contributes to the body of knowledge showing that anthracyclines have a limited role in systemic treatment of oesophagogastric cancer.2 However, we urge caution in the interpretation of this study confirming that two neoadjuvant cycles of CF is standard of care for patients with resectable oesophageal adenocarcinoma.

    更新日期:2017-11-01
  • Concordance between plasma-based and tissue-based next-generation sequencing in LOTUS
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-01
    Sung-Bae Kim, Rebecca Dent, Matthew J Wongchenko, Stina M Singel, José Baselga
    更新日期:2017-11-01
  • Adequate SIRT activity dose is as important as adequate chemotherapy dose – Authors' reply
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-01
    Ricky A Sharma, Peter Gibbs, Navesh K Sharma, Jens Ricke, Julien Taieb, Joanna Moschandreas, Pradeep S Virdee, Peter Dutton, Guy van Hazel, Harpreet S Wasan

    The FOXFIRE, SIRFLOX, and FOXFIRE-Global studies investigated the efficacy of combining first-line chemotherapy for metastatic colorectal cancer with selective internal radiotherapy (SIRT) using yttrium-90 resin microspheres in patients with liver metastases.1 The studies were designed for a prospective, combined analysis of overall survival, but also reported secondary endpoints including radiological response and liver-specific progression-free survival.

    更新日期:2017-11-01
  • Adequate SIRT activity dose is as important as adequate chemotherapy dose
    Lancet Oncol. (IF 33.9) Pub Date : 2017-11-01
    Arthur J A T Braat, S Cheenu Kappadath, Rutger C G Bruijnen, Andor F van den Hoven, Armeen Mahvash, Hugo W A M de Jong, Marnix G E H Lam

    In their Article, Harpreet Wasan and colleagues1 reported a combined analysis of three prospective randomised controlled trials (SIRFLOX, FOXFIRE, and FOXFIRE-Global) that compared a regimen of first-line leucovorin, fluorouracil, and oxaliplatin (FOLFOX) plus selective internal radiotherapy (SIRT) with yttrium-90 resin microspheres with FOLFOX alone in patients with colorectal cancer with liver metastases. They found no survival benefit for the FOLFOX plus SIRT group (median overall survival 22·6 months [95% CI 21·0–24·5] with FOLFOX plus SIRT vs 23·3 months [21·8–24·7] with FOLFOX alone; p=0·61).

    更新日期:2017-11-01
Some contents have been Reproduced with permission of the American Chemical Society.
Some contents have been Reproduced by permission of The Royal Society of Chemistry.
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