包慧敏 - 复旦大学

个人简介

学习工作经历 2001.07 - 至今复旦大学化学系，讲师，2013年晋升副教授 1999.07-2001.06 上海医科大学基础医学院，助教 2012.04-2013.04 美国北卡莱罗那大学（教堂山分校）UNC-CH，访问学者 2002.09-2008.06 复旦大学化学系，获分析化学博士学位 1995.09-1999.06 华东师范大学化学系，获理学学士学位获奖情况 2010年复旦大学复华奖（三等奖） 2015年复旦大学 “研究生十佳辅导员” 2016年复旦大学 “优秀教工支部”（任支部书记） “2019年度上海药学科技奖”（基础研究类）二等奖，排名2

研究领域

本人从事化学蛋白质组学新技术及其在生物医学中的应用研究。发展基于生物正交反应的化学蛋白质组学新技术，用于细胞中新生蛋白质的研究；发展基于炔基嘌呤霉素代谢标记建立正在翻译新生肽链的新方法，用于蛋白翻译过程研究；本人从事化学蛋白质组学新技术及其在生物医学中的应用研究。

近期论文

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Peiyi Meng, Yuyin Shao, Yingying Xiong, Lei Zhang, Huimin Bao*,Haojie Lu*. Peptide- and Protein-Level Combined Strategy for Analyzing Newly Synthesized Proteins by Integrating Tandem Orthogonal Proteolysis with Cleavable Bioorthogonal Tagging. Anal. Chem. 2023, 95, 628−637. Yuyin Shao, Huimin Bao,* Lixiang Ma, Wenjuan Yuan, Lei Zhang, Jun Yao, Peiyi Meng, Ye Peng, Siwen Zhang, Ting Cao, and Haojie Lu.* Enhancing Comprehensive Analysis of Newly Synthesized Proteins Based on Cleavable Bioorthogonal Tagging. Analytical chemistry, 2021, 93, 27, 9408–9417. Jingtian Lu, Ting Wang, Huimin Bao, Haojie Lu.* Fractionation-free negative enriching for in-depth C-terminome analysis. Chinese Chemical Letters, 2021 (online,doi:10.1016/j.cclet.2021.08.022). Huimin Bao, Liqi Xie, Haojie Lu.* Research advances of enrichment approaches based on chemical reactions in glycoproteomics. Chinese Journal of Chromatography, 2016, 34(12): 1145-1153. Huimin Ge, Huimin Bao, Luyan Zhang, Gang Chen.* Preparation of porous graphene using cuprous oxide microspheres as sacrificial templates for enriching proteins and peptides. CARBON, 2015, 82: 579-589. Huimin Bao, Luyan Zhang, Gang Chen.* Immobilization of trypsin via graphene oxide-silica composite for efficient microchip proteolysis. J. Chromatography A, 2013, 1310: 74-81. Huimin Bao, Shuang Liu, Luyan Zhang, Gang Chen.* Efficient sample proteolysis based on a microchip containing a glass fiber core with immobilized trypsin. Microchim Acta, 2012, 179: 291–297. Huimin Bao, Qiwen Chen, Luyan Zhang, Gang Chen.* Immobilization of trypsin in the layer-by-layer coating of graphene oxide and chitosan on in-channel glass fiber for microfluidic proteolysis. Analyst, 2011, 136(24), 5190-5196. Huimin Bao, Peiming Song, Qingping Liu, Yinkun Liu, Dong Yun,Hexige Saiyin, Ruyun Du, Yang Zhang, Huizhi Fan, Pengyuan Yang, Xian Chen.* Quantitative proteomic analysis of a paired human liver healthy versus carcinoma cell lines with the same genetic background to identify potential hepatocellular carcinoma markers. Proteomics Clin. Appl. 2009, 3: 705–719. Huimin Bao, Ting Liu, Luyan Zhang, Gang Chen.* Infrared-assisted proteolysis using trypsin-immobilized silica microspheres for peptide mapping. Proteomics. 2009, 9: 1114–1117.