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个人简介

1962年10月出生于湖南澧县。1978-1982年就读于大连理工大学染料及中间体专业,获学士学位,随后在武汉染料厂工作,1983年考取大连理工大学精细化工专业研究生,1986年获硕士学位,1990年获博士学位,1992年在南开大学完成有机化学专业博士后工作,回到大连理工大学化工学院工作,1996年破格晋升为教授,1997年起任精细化工国家重点实验室主任,2019年起任化工学院院长,2020年起任大连理工大学深圳研究院院长。长期从事精细化工领域研究:从基础理论研究出发,形成了近红外比率荧光菁染料探针分子平台,为解决复杂体系荧光信息的定量获取提供了新方法,被国内外广泛应用;构建的耐候性喷墨打印染料产品体系,大规模产业化,为我国成为彩色喷墨打印耗材大国,做出了重要贡献;创制的荧光探针在血液细胞分析系统的产业化应用,促进了我国在血液临床分析装备领域从空白到国际一流的跨越。发表论文350余篇,授权国内外发明专利50余项,参与起草国家标准20余项、ISO国际标准5项。作为第一完成人,获2013年国家自然科学二等奖和2006年国家技术发明二等奖,以及4项省部级一等奖/特等奖。2001年获国务院政府特殊津贴,2007年获国家杰出青年科学基金,入选教育部“长江学者奖励计划”特聘教授。2008年被评为全国化工优秀科技工作者, 2016年被评为全国优秀科技工作者,2017年当选中国科学院院士,2020年获全国创新争先奖。

研究领域

1. 功能性染料及其应用 染料分子结构与功能的调控;染料超分子体系的光诱导分子内电子转移、电荷转移、能量转移;数码打印用染料及信息记录材料。 2. 染料荧光探针 荧光染料的识别及荧光响应的调控,荧光探针及其在生物分析、医学诊断、环境监测中的应用。 3. 精细化学品清洁制备技术 精细化学品合成新技术、功能微球的构建技术、精细化工节能降耗新技术。

近期论文

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Liu W, Gu H, Liu W, Lv C, Du J, Fan J, Peng X, NIR-emitting carbon dots for discriminative imaging and photo-inactivation of pathogenic bacteria. Chemical Engineering Journal., 2022, 6 , 137384. Zou Y, Liu W, Sun W, Du J, Fan J,* and Peng X. Highly Inoxidizable Heptamethine Cyanine-Glucose Oxidase Conjugate Nanoagent for Combination of Enhanced Photothermal Therapy and Tumor Starvation. Adv. Funct. Mater. 2022 ,2111853. Xiong T, Chen Y, Li M, Long S, Du J, Fan J, Jia L, Peng X. A benzophenoxazine-dyad as cancer indicator using for fluorescence-guided phototherapy. Sens. Actuators, B., 2022, 352 , 130990. Ge H, Du J, Zheng J, Xu N, Yao Q, Long S, Fan J, Peng X. Effective treatment of cisplatin-resistant ovarian tumors with a MoS2-based sonosensitizer and nanoenzyme capable of reversing the resistant-microenvironment and enhancing ferroptosis and apoptosis. Chem. Eng. J., 2022, 446 , 137040. Ge H, Du J, Long S, Xia X, Zheng J, Xu N, Yao Q, Fan J, Peng X. Near-Infrared Light Triggered H2 Generation for Enhanced Photothermal/Photodynamic Therapy against Hypoxic Tumor. Adv. Healthcare Mater., 2022, 11 , 2101449. Zheng J, Du J, Ge H, Xu N, Yao Q, Long S, Fan J, Peng X. Viscosity-dependent photocatalysis triggers ferroptosis and Type-I photodynamic therapy to kill drug-resistant tumors. Chem. Eng. J., 2022, 449 , 136565. Tianping Xia, Gengwen Chen, Danhong Zhou, Weijian Liu, Xiaojing Li, Hua Gu, Yi Ye, Jianjun Du, Jiangli Fan, and Xiaojun Peng. Nucleic Acid Probe-Based Difunctional Hematology Analysis Kit for Peripheral Blood Cell Analysis. ACS Sens., 2022, 7 , 469−476. Du J, Shi T, Long S, Chen P, Sun W, Fan J, Peng, X. Enhanced photodynamic therapy for overcoming tumor hypoxia: From microenvironment regulation to photosensitizer innovation. Coord. Chem. Rev., 2021, 427, 213604. Li H, Kim D, Yao Q, Ge H, Chung J, Fan J, Wang J, Peng, X, Yoon J. Activity-Based NIR Enzyme Fluorescent Probes for the Diagnosis of Tumors and Image-Guided Surgery. Angew. Chem., Int. Ed., 2021, Ahead of Print. Li H, Yao Q, Pu Z, Chung J, Ge H, Shi C, Xu N, Xu F, Sun W, Du J, Fan J, Wang J, Yoon J, Peng, X. Hypoxia-activatable nano-prodrug for fluorescently tracking drug release in mice. Sci. China: Chem., 2021, 64 (3), 499-508. Li M, Sun W, Tian R, Cao J, Tian Y, Gurram B, Fan J, Peng, X. Smart J-aggregate of cyanine photosensitizer with the ability to target tumor and enhance photodynamic therapy efficacy. Biomaterials, 2021, 269, 120532. Ran B, Yuan Y, Xia W, Li M, Yao Q, Wang Z, Wang L, Li X, Xu Y, Peng, X. A photo-sensitizable phage for multidrug-resistant Acinetobacter baumannii therapy and biofilm ablation. Chem. Sci., 2021, 12 (3), 1054-1061 Xia W, Li H, Li Y, Li M, Fan J, Sun W, Li N, Li R, Shao K, Peng, X. In Vivo Coinstantaneous Identification of Hepatocellular Carcinoma Circulating Tumor Cells by Dual-Targeting Magnetic-Fluorescent Nanobeads. Nano Lett., 2021, 21 (1), 634-641. Xia W, Zhang S, Fan J, Li Y, Peng, X. Imaging and inhibiting cyclooxygenase-2 using aspirin-based fluorescent reporter for the treatment of breast cancer. Sens. Actuators, B, 2021, 329, 129217. Xiong T, Li M, Chen Y, Du J, Fan J, Peng, X. A singlet oxygen self-reporting photosensitizer for cancer phototherapy. Chem. Sci., 2021, 12 (7), 2515-2520. Xu F, Ge H, Xu N, Yang C, Yao Q, Long S, Sun W, Fan J, Xu X, Peng, X. Radical induced quartet photosensitizers with high 1O2 production for in vivo cancer photodynamic therapy. Sci. China: Chem., 2021, 64 (3), 488-498. Zhang Z, Fan J, Du J, Peng, X. Two-channel responsive luminescent chemosensors for dioxygen species: Molecular oxygen, singlet oxygen and superoxide anion. Coord. Chem. Rev., 2021, 427, 213575. Zhao X, Liu J, Fan J, Chao H, Peng, X. Recent progress in photosensitizers for overcoming the challenges of photodynamic therapy: from molecular design to application. Chem. Soc. Rev., 2021, Ahead of Print. Zou Y, Long S, Xiong T, Zhao X, Sun W, Du J, Fan J, Peng, X. Single-Molecule Förster Resonance Energy Transfer-Based Photosensitizer for Synergistic Photodynamic/Photothermal Therapy. ACS Cent. Sci., 2021, 7 (2), 327-334.

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