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个人简介

1988、 1991 和 1994 年先后获北京大学理学学士、硕士和博士学位 1994-1998 年,北京大学化学学院工作 1999-2000,美国堪萨斯大学 药化系 CDDR 博士后 2000至今 北京大学化学学院工作

研究领域

光学传感新原理、新方法。 基于金属纳米材料光谱(荧光、局域表面等离子体共振吸收/散射)的生物传感

近期论文

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Rong Sheng Li, Jia Hui Liu, Hu Shi*, Ping Ping Hu, Yao Wang, Peng Fei Gao, Jian Wang, Moye Jia, Hongwei Li, Yuan Fang Li, Chengde Mao*, Na Li*, Cheng Zhi Huang*Transformable Helical Self-Assembly for Cancerous Golgi Apparatus Disruption.Nano Lett. 2021, 21 (19), 8455–8465 Rongsheng Li, Jiahui Liu, Yuan Yan, Chuanyang Su, Tiancheng Lai, Yunwen Liao, Yuan Fang Li, Na Li*, Cheng Zhi Huang*Aggregation-Enhanced Energy Transfer for Mitochondria-Targeted ATP Ratiometric Imaging in Living Cells.Anal. Chem. 2021, 93 (34), 11878–11886 Guangyu Tao, Xiao Xu, Rong Sheng Li, Feng Liu, and Na Li*Nonamplification Multiplexed Assay of Endonucleases and DNA Methyltransferases by Colocalized Particle Counting ACS Sens., 2021, 6, 1321–1329 Guangyu Tao, Tiancheng Lai, Xiao Xu, Yurou Ma, Xi Wu, Xiaojing Peo, Feng Liu, Na Li*Colocalized Particle Counting Platform for Zeptomole Level Multiplexed Quantification Anal. Chem., 2020, 92, 3697–3706 Tian Li, Xi Wu, Guangyu Tao, Haoyan Yin, Junlong Zhang, Feng Liu, Na Li*A simple and non-amplification platform for femtomolar DNA and microRNA detection by combining automatic gold nanoparticle enumeration with target-induced strand-displacement Biosens. Bioelectron. 2018, 105, 137–142. Xiaojing Pei, Tiancheng Lai, Guangyu Tao, Hu Hong, Feng Liu, and Na Li*Ultra-specific multiplexed detection of low-abundance single-nucleotide variants by combining masking tactic with fluorescent nanoparticle counting Anal. Chem., 2018, 90, 4226–4233 Xiaojing Pei, Haoyan Yin, Tiancheng Lai, Junlong Zhang, Feng Liu, Xiao Xu*, Na Li*Multiplexed Detection of Attomole Nucleic Acids Using Fluorescent Nanoparticle Counting Platform Anal. Chem., 2018, 90, 1376–1383 Guangyu Tao, Yang Chen, Ruoyun Lin, Jiang Zhou, Xiaojing Pei, Feng Liu, Na Li How G-quadruplex topology and loop sequences affect optical properties of DNA-templated silver nanoclusters Nano Res. 2017, 11, 223–2247 Ruoyun Lin, Guangyu Tao, Yang Chen, Mingxing Chen, Feng Liu, and Na Li*.Constructing a robust fluorescent DNA-stabilized silver nanocluster probe module by attaching a duplex moiety Chem. Eur. J., 2017, 23, 10893–10900 Runyun Lin, Chenxi Li, Yang Chen,.Feng Liu, and Na Li*Metal-enhanced fluorescence in biosensing applications, "Surface Plasmon Enhanced, Coupled and Controlled Fluorescence", 2017, Edited by Geddes, C. D., Wiley, NJ. (Invited chapter) Tian. Li, Xi Wu, Feng Liu, and Na Li*. Analytical Methods Based on the Light-Scattering of Plasmonic Nanoparticles at the Single Particle Level with Dark-Field Microscopy Imaging Analyst, 2017, 142, 248–56.(Ivited Review) Tian Li, Xiao Xu, Guoqing Zhang, Ruoyun Lin, Yang Chen, Chenxi Li, Feng Liu, and Na Li*'Nonamplification Sandwich Assay Platform for Sensitive Nucleic Acid Detection Based on Aunps Enumeration with the Dark-Field Microscope Anal. Chem., 2016, 88, 4188–91. Xiao Xu, tian Li, Zhongxing Xu, Hejia Wei, Ruoyun Lin, Bin Xia, Feng Liu, Na Li*Automatic enumeration of gold nanomaterials at single particle level.Anal. Chem. 2015, 87, 2576–2581 Hongduan Huang, Hejia Wei, Mingjian Zou, Xiao Xu,Bin Xia*, Feng Liu, Na Li*Modulating fluorescence anisotropy of terminally labeled dsDNA via the interaction between dye and nucleotides for rational design of DNA-recognition based applications. Anal. Chem. 2015, 87, 2748–2754 Zhenpeng Zhou, Tian Li, Hongduan Huang, Yang Chen, Feng Liu, Chengzhi Huang,* and Na Li*A dual amplification strategy for DNA detection combining bio-barcode assay and metal-enhanced fluorescence modality Chem. Commun., 2014, 50, 13373–13376 Chenxi Li, Yixin Li, Xiao Xu, Xinyi Wang, Yang Chen, Xiaoda Yang, Feng Liu, and Na Li*Fast and quantitative differentiation of single-base mismatched DNA by initial reaction rate of catalytic hairpin assembly.Biosens. Bioelectron. 2014, 60, 57–63. Zhenpeng Zhou, Hongduan Huang, Yang Chen, Feng Liu, Chengzhi Huang, Na Li*A distance-dependent metal-enhanced fluorescence sensing platform based on molecular beacon design Biosens. Bioelectron. 2014, 52, 367–373 Xinyi Wang, Mingjian Zou, Hongduan Huang, Yuqian Ren, Limei Li, Xiaoda Yang, Na Li*Gold nanoparticle enhanced fluorescence anisotropy for the assay of single nucleotide polymorphisms (SNPs) based on toehold-mediated strand-displacement reaction Biosens. Bioelectron. 2013, 41, 569–575 Xiao Xu, Yang Chen, Hejia Wei, Bin Xia, Feng Liu and Na Li*Counting Bacteria Using Functionalized Gold Nanoparticles as the Light-Scattering Reporter Anal. Chem. 2012, 84, 9721–9728. Mingjian Zou, Yang Chen, Xiao Xu, Hongduan Huang, Feng Liu, Na Li* The homogeneous Fluorescence Anisotropic Sensing of Salivary Lysozyme Using the 6-carboxyfluorescein-labeled DNA Aptamer Biosens. Bioelectron. 2012, 32, 148–154

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