龚国清 - 中国药科大学

个人简介

龚国清男，1966年8月生。1987年中国药科大学药理专业本科毕业，1990年获药理专业硕士学位，2004年获得药理学博士学位。现任药学院药理教研室副教授，药学医学基础实验中心副主任。

研究领域

生化药理。主要研究创新化合物的抗血栓作用、抗炎作用及其机理

近期论文

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1. Shaochi Wang, Peng Dai, Yungen Xu, Qiufang Chen, Qihua Zhu, Guoqing Gong*(通讯作者)Design, Synthesis, and Biological Evaluation of Dabigatran Etexilate Mimics, A Novel Class of Thrombin Inhibitors Arch. Pharm. Chem. Life Sci. 2015, 348, 595-605 2. Mei-Ling Jiang, Zhi-Xian Zhang, Yun-Zhan Li , Xin-Hui Wang, Wei Yan, Guo-Qing Gong*(通讯作者) Antidepressant-like effect of evodiamine on chronic unpredictable mild stress rats Neuroscience Letters 588 (2015) 154-158 3. Yun Yang , Xinhui Wang , Qihua Zhu , Guoqing Gong *(通讯作者), Danmeng Luo , Aidou Jiang , Liyan Yang ,Yungen Xu , Synthesis and pharmacological evaluation of novel limonin derivatives as anti-inflammatory and analgesic agents with high water solubility Bioorganic & Medicinal Chemistry Letters 24 (2014) 1851-1855 4. Xinhui Wang, Guoqing Gong*(通讯作者), Wenhui Yang, Yunzhan Li, Meiling Jiang, Linlin Li Antifibrotic activity of galangin, a novel function evaluated in animal liver fibrosis model Environmental Toxicology and Pharmacology 36(2013)288-295 5. Yun-Zhan Li , Guo-Qing Gong *(通讯作者), Wen-Hui Yang , Xin-Hui Wang , Mei-Ling Jiang , Yi Zhou ,Xiao-Zhi Yang , Yun-Gen Xu , Guang-Wei He Antithrombotic activity of HY023016, a novel Dabigatran prodrug evaluated in animal thrombosis models Thrombosis Research 131 (2013) 425-435 6. Yi Zhou, Guoqing Gong*(通讯作者), Wenhui Yang, Yin Wang, Jing Xu, Yungen Xu The cardioprotective effect of TG-6, a newly synthesized compound, on ischemia-reperfusion injury in rats European Journal of Pharmacology 683 (2012) 190-196 7. Xiao-Zhi Yang , Wen-Hui Yang , Yun-Gen Xu* , Xiao-Juan Diao , Guo-qing Gong**(通讯作者) Synthesis and antithrombotic evaluation of novel dabigatran prodrugs containing a cleavable moiety with anti-platelet activitys European Journal of Medicinal Chemistry 57 (2012) 21-28 8. Lu Jin, Xiang-Min Jiang, Ping Du, Jing Xu, Guo-qing Gong**(通讯作者), Qiu-juan Wang, Yun-gen Xu* Synthesis and Na+/H+ exchanger inhibitory activityof benzoylguanidine derivatives. European Journal of Medicinal Chemistry,2011,46:4107-4116