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个人简介

1963年7月生,毕业于中国药科大学生物制药专业和南京大学生命科学学院植物学专业,获博士学位。1993年曾赴日本歧阜药科大学分子生物实验室作访问学者。 1983年留校任教以来,一直从事教学、科研和管理工作。现任中国药科大学微生物与生化药学教授(博士生导师)、中国药科大学生命科学与技术学院院长。为国务院学位委员会第六届学科评议组药学组成员,国家食品药品监督管理局新药、保健食品评审专家,中国药学会生化与生物技术药物专业委员会委员,中国生物化学与分子生物学会工业生物化学与分子生物学分会常务理事,中国微生物学会海洋药物委员会理事,《中国药科大学学报》、《药物生物技术》、《药学进展》、《食品与药品》等杂志编委。

研究领域

生物新药研制、生物大分子结构与功能研究和衰老的分子生物学研究

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Guo W, Luo C, Wang C, Zhu Y, Wang X, Gao XD. Protection against Th17 Cells Differentiation by an Interleukin-23 Receptor Cytokine-Binding Homology Region. 2012, 7(9): e45625 2. Chen S, Liu AR, An FM, Yao WB, Gao XD. Amelioration of neurodegenerative changes in cellular and rat models of diabetes-related Alzheimer’s disease by exendin-4. AGE. 2012, 34(5):1211-1224 3. Jin L, Guan X, Liu W, Zhang X, Yan W, Yao WB, Gao XD. Characterization and antioxidant activity of a polysaccharide extracted from Sarcandra Glabra. Carbohydr Polym. 2011, 90(1): 524-532 4. Niu YG, Wang HY, Xie ZH, Whent M, Gao XD, Zhang X, Zou S, Yao WB, Yu LL. Structural Analysis and Bioactivity of a Polysaccharide from the Roots of Astragalus membranaceus (Fisch) Bge. var. mongolicus (Bge.) Hsiao. Food Chem. 2011, 128(3): 620–626 5. Wang JJ, Zhao H, Zheng Y, Liu W, Zhou H, Han ARN, Gao XD. Monoclonal Antibodies to Sea Cucumber Polysaccharide and Their Use in a Sandwich ELISA Assay. Hybridoma. 2011, 30(4): 381-385 6. Sun JJ, Song XD, Tian H, Jin YH, Gao XD, Yao WB. Synthesis of a novel Histidine-Targeting poly (ethylene glycol) and modification of lysozyme. Journal of Applied Polymer Science. 2011, 119(4): 2183-2188 7. Ren M, Yan W, Yao WB, Jin L, Gao XD. Enzymatic degradation products from a marine polysaccharide YCP with different immunological activity and binding affinity to macrophages, hydrolyzed by α-amylases from different origins. Biochimie. 2010, 92(4): 411-417 8. Liu W, Wang HY, Yao WB, Gao XD, Yu LL. Effects of Sulfation on the Physicochemical and Functional Properties of a Water-Insoluble Polysaccharide Preparation from Ganoderma lucidum. J Agr Food Chem. 2010, 58(6): 3336–3341 (IF2.469) 9. Liu W, Xie ZH, Zhang BC, Wang Q, Yao WB, Gao XD and Yu LL. Effects of Hydroxypropylation on the Functional Properties of Psyllium. J Agr Food Chem. 2010, 58(3): 1615–1621 10. Liu W, Zhang BC, Wang Q, Xie ZH, Yao WB, Gao XD and Yu LL. Effects of Sulfation on the Physicochemical and Functional Properties of Psyllium. J Agr Food Chem. 2010, 58(1): 172–179 11. Liu W, Wang HY, Pang XB, Yao WB, Gao XD. Characterization and antioxidant activity of two low-molecular-weight polysaccharides purified from the fruiting bodies of Ganoderma lucidum. Int J Biol Macromol. 2010, 46(4): 451-457 12. Tong Y, Zhong K, Tian H, Gao XD, Xu XY, Yin XJ, Yao WB. Characterization of a mono PEG20000-Endostar. Int J Biol Macromol. 2010, 46(3): 331-336 13. Ma C, Gao MM, Liu WC, Zhu J, Tian H, Gao XD, Yao WB. Intein-mediated Expression and Purification of an Analog of Glucagon-like Peptide-1 in Escherichia coli. Protein Pept Lett. 2010, 17(10): 1245-1250 14. Gao MM, Ma C, Liu WC, Zhu J, Tian H, Gao XD, Yao WB. Production and purification of an analog of glucagon-like peptide-1 by auto-induction and on-column cleavage in Escherichia coli. World J Microbiol Biotechnol. 2010, 26(9): 1675–1682 15. Gao MM, Tian H, Ma C, Gao XD, Guo W, Yao WB. Expression, Purification, and C-terminal Site-Specific PEGylation of Cysteine-Mutated Glucagon-Like Peptide-1. Appl Biochem Biotechnol. 2010, 162(1): 155-165 16. Liu W, Xu J, Jing P, Yao WB, Gao XD, Yu LL. Preparation of a hydroxypropyl Ganoderma lucidum polysaccharide and its physicochemical properties. Food Chem. 2010, 122(4): 965–971 17. Zou S, Zhang X, Yao WB, Niu YG, Gao XD. Structure characterization and hypoglycemic activity of a polysaccharide isolated from the fruit of Lycium barbarum L. Carbohydr Polym. 2010, 80(4): 1161-1167 18. Song XD, Sun JJ, Tian H, Gao XD. Gold nanoparticles combined with highly expressed amber suppressor tRNA: a future antibacterial agent. Irn J Med Hypotheses Ideas. 2010, 4: 6 19. Xu J, Liu W, Yao WB, Pang XB, Yin DK, Gao XD. Carboxymethylation of a polysaccharide extracted from Ganoderma lucidumen hances its antioxidant activities in vitro. Carbohydr Polym. 2009, 78(2): 227–234 20. Chen S, Yin DK, Yao WB, Wang YD, Zhang YR, Gao XD. Macrophage receptors of polysaccharide isolated from a marine filamentous fungus Phoma herbarum YS4108. Acta Pharmacologica Sinica. 2009, 30(7): 1008-1014 21. Yin DK, Yao WB, Chen S, Hu RF, Gao XD. Salidroside, the Main Active Compound of Rhodiola Plants, Inhibits High Glucose-Induced Mesangial Cell Proliferation. Planta Med. 2009, 75(11): 1191-1195

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