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个人简介

2019.10-至今:中国农业大学,人才培育发展计划“青年新星A”,特聘研究员 2016.03-2019.09:中国农业大学,优秀人才引进,副教授 2011.11-2016.02:北京化工大学,副教授 2007.09-2011.10:荷兰瓦格宁根大学,博士 2005.09-2007.08:荷兰瓦格宁根大学,硕士 2001.09-2005.06:中国农业大学,学士 课题项目 国家自然科学基金面上项目,31972202,乳清蛋白胶粒Pickering乳液稳定界面的构效关系及其调控食品质构和脂肪消化的机制研究,2020/01-2023/12,58万,主持 国家自然科学基金面上项目,31772014,酸性羧基肽纳米自组装食品功能因子载体与肠粘液层相互作用机制研究,2018/01-2021/12,60万元,主持 国家自然科学基金面上项目,31471577,乳清蛋白载体用于食品活性因子稳态化的作用机制研究, 2015/01-2018/12,85万元,已结题,主持 国家自然科学基金青年项目,31201334,氧化淀粉水凝胶构效关系及对吸附缓释脂溶性营养素性能调控机制的研究, 2013/01-2015/12,25万元,已结题,主持 北京市委组织部“北京市优秀人才青年拔尖人才”, 2019/01-2021/12,50万元,主持 北京市科委人才计划“北京市科技新星计划”,2018/01-2020/12,35万元,主持

研究领域

食源性活性成分的靶向精准递送 食品功能性胶体与功能食品开发 食品软物质与新型物理化学食品加工技术

近期论文

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Liu B, Li T,Wang W.Y, Sagis M.C. L, Yuan Q.P, Lei X.G, Cohen Stuart A.M, Li D, Bao C, Bai J, Yu Z.Q, Ren F.Z*,Li Y*.Corncob cellulose nanosphere as an eco-friendly Detergent. Nature Sustainability, DOI:10.1038/s41893-020-0501-1 Bao W.R, Liu X.W., Lv Y.L,Lu G.H, Li F, Zhang F,Liu B,Li D, Wei W*,Li Y*.Nanolongan with Multiple On-Demand Conversions for Ferroptosis?Apoptosis Combined Anticancer Therapy. ACS Nano. 2019.13,260-273. IF=15.149 Bao C, Liu B, Li B, Chai J.J, Zhang L.W, Jiao L.L, Li D, Yu Z.Q, Ren F.Z, Shi X.H*.Li Y.*. Enhanced Transport of Shape and Rigidity-tuned α-lactalbumin Nanotubes across Intestinal Mucus and Cellular Barriers. Nano Letters 2020,20,1352-1361 IF=13.969 Tian Y.H , Xu J.Z, Li Y(并列一作), Zhao R, Du S.J, Lv C,Wu W, Liu R.Q, Sheng X.L, Song Y.L, Bi X.Y, Li G.L, Li M.Z, Wu X, Lou P.B, You H.W,Cui W, Sun J.Y, Shuai J.W, Ren F.Z, Zhang B, Guo M.Z, Hou X.H, Wu K.C, Xue L.X, Zhang H.Q, Plikus M.V, Cong Y.Z, Lengner C.J, Liu Z.J*, Yu Z.Q*.MicroRNA-31 Reduces Inflammatory Signaling and Promotes Regeneration in Colon Epithelium, and Delivery of Mimics in Microspheres Reduces Colitis in Mice, Gastroenterology, 2019,156,2281-2296. IF= 19.066,封面文章 Zhao R, Du, S.J, Liu Y, Lv C, Song, Y.L, Chen X.C, Zhang B, Li D, Gao S, Cui W, Plikus,M.V Hou X.H, Wu K.C, Liu Z.J, Liu Z.H, Cong Y.Z, Y Li*, Yu,Z.Q * Mucoadhesive-to-penetrating controllable peptosomes-in-microspheres co-loaded with anti-miR-31 oligonucleotide and Curcumin for targeted colorectal cancer therapy.Theranostics,2020,10,3594-3611. IF=8.651,封面文章 Teng W.D, Zhao L.Y, Yang S.T, Zhang C.Y, Liu M.Y, Luo J, Jin J.H, Zhang M, Bao C, Li D, Xiong W, Li Y*, Ren F*. The hepatic-targeted, resveratrol loaded nanoparticles for relief of high fat diet-induced nonalcoholic fatty liver disease. Journal of Controlled Release, 2019,307,139-149. IF=8.375 Li Y*,Li W,Bao W.R, Liu B, Li D, Jiang Y.M, Wei.W, Ren F.Z*. Bioinspired Peptosomes with Programmed Stimuli-responses for Sequential Drug Release and High-performance Anticancer Therapy. Nanoscale 2017,9,9317-9324. IF=7.719,封面文章 Chai J.J Jiang P, Wang P.J, Jiang Y.M, Li D, Bao W.E, Liu B.X, Liu B, Zhao L.Y, Norde W, Yuan Q.P, Ren F.Z, Li Y*. The intelligent delivery systems for bioactive compounds in foods: Physicochemical and physiological conditions, absorption mechanisms, obstacles and responsive strategies. Trends in Food Science and Technology 2018, 78,144-154. IF= 9.303. Chen X.D, Wang S.S, Yuan Q.P, Norde W, Li Y*. Formation and characterization of light-responsive TEMPO-Oxidized Konjac Glucomannan Microspheres. Biomacromolecules 2014. 15, 2166-2171, 2014.IF=6.432. Li D, Jiang Y.M, Jiao L.L, Bao C, Li Y*.Synergistically enhanced anticancer effect of co-delivered Cur and siPlk1 by stimuli-responsive α-lactalbumin nanosphere. Nanomedicine 2019, 14,595-612.IF= 5.217 Li D, Liu A.L, Liu M.Y, Li X, Guo H.Y, Zuo C.C, Li Y*,The intestine-responsive lysozyme nanoparticles-in-oxidized starch microgels with mucoadhesive and penetrating properties for improved epithelium absorption of quercetin. Food Hydrocolloids 2020, 99 105309. IF=6.103 Du Y.Z, Bao C, Huang J, Jiang P, Jiao L, Ren F.Z, Li Y*. Improved stability, epithelial permeability and cellular antioxidant activity of β-carotene via encapsulation by self-assembled α-lactalbumin micelles. Food Chemistry 2019,217,707-714. IF= 5.488 Liu B., Xu H., Zhao H.Y., Liu W., Zhao L.Y., Li Y*.Preparation and characterization of intelligent starch/PVA films for simultaneous colorimetric indication and antimicrobial activity for food packaging applications. Carbohydrate Polymers.157, 842-849, 2017. IF=5.326 Shi M.X., Bai J., Zhao L.Y., Yu X.Y., Liang J.J., Liu Y., Norde W., Li Y*. Co-loading and intestine-specific delivery of multiple antioxidants in pH-responsive microspheres based on TEMPO-oxidized polysaccharides. Carbohydrate Polymers.157, 858-865, 2017. IF=5.326 Jiang P, Huang J, Bao, C, Jiao, L, Zhao H, Du, Y, Ren F, Li, Y*. Enzymatically partial hydrolyzed α-lactalbumin peptides for self-assembled micelles formation and their application for co-encapsulation of multiple anti-oxidants. Journal of Agricultural and Food Chemistry 2018, 66, 12921-12930. Bao C, Jiang? P?, Chai?? J.J, ?Jiang? Y.M, Li D?, Bao W.E?, Liu B.X?, Liu? B,Norde W?, Li? Y*, The delivery of sensitive food bioactive ingredients: Absorption mechanisms, influencing factors, encapsulation techniques and evaluation models. ?Food research International 2019. 120,130-140. Hu Y.L, Bao,C, Li,D, You L.X, Du Y.Z, Liu B, Li,X,Ren F.Z, Li Y*. The construction of enzymolyzed α-lactalbumin based micellar nanoassemblies for encapsulating various kinds of hydrophobic bioactive compounds Food and Function 2019. 2019, 10, 8263-8272. Jiang Y.M,Li T,Lu M.L,Li D,Ren F.Z, Zhao H.Y*,Li Y*. TEMPO-oxidized starch nanoassemblies of negligible toxicity compared with polyacrylic acids for high performance anti-cancer therapy. International Journal of Pharmaceutics 2018, 547,520-529. Liu B, Zhu Y.L, Tian J.N, Guan T, Li D, Bao C, Norde W, Wen P.C, Li Y*.Inhibition of oil digestion in Pickering emulsions stabilized by oxidized cellulose nanofibrils for lowcalorie food design. RSC Advances, 2019, 9, 14966-14973. Wu J.D, Shi M.X, Li W, Zhao L.H, Wang Z, Yan X.Z, Norde W, Li Y*.Pickering emulsions stabilized by whey protein nanoparticles prepared by thermal cross-linking. Colloids and Interfaces B:Biointerfaces.127, 96-104, 2015. 陈钰莹,陈小冬,史梦璇,路美玲,赵陆海,李媛*,TEMPO氧化魔芋微球的制备及其在运载食品活性因子中的应用,食品科学,2016,37,1-6。(入选“领跑者5000——中国精品科技期刊顶尖学术论文”)

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