陈刚 - 上海交通大学 - 化学化工学院

个人简介

教育经历 09/2007-06/2012 中国科学院上海有机化学研究所，上海，博士（导师：袁承业，马大为研究员） 09/2003-06/2007 东南大学，南京，学士（导师：葛裕华教授）工作经历 07/2012-02/2013中国科学院上海有机化学研究所，上海，助理研究员（合作导师：袁承业，马大为研究员） 03/2013-10/2017 美国斯克利普斯研究所 (The Scripps Research Institute)，圣地亚哥，博士后（合作导师：Prof.Jin-Quan Yu） 10/2017-08/2018美国斯克利普斯研究所 (The Scripps Research Institute)-Calibr，圣地亚哥，博士后（合作导师：Mike Petrassi，Peter Schultz 教授） 09/2018-至今上海交通大学化学化工学院，上海，特别研究员

研究领域

发展和应用新的方法学用于活性天然产物的高效和多样性合成，用于免疫疗法新靶标的药物化学和化学生物学研究。

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Gang Chen‡, Wei Gong‡, Zhe Zhuang, Michal S. Andra, Yan-Qiao Chen, Xin Hong, Yun-Fang Yang, Tao Liu, K. N. Houk*, Jin-Quan Yu*. "Ligand-Accelerated Enantioselective Methylene C(sp3)-H Bond Activation" Science 2016, 353, 1023. (Highlighted on C&EN News and Cell Chemistry) (‡ Co-first author) Gang Chen, Toshihiko Shigenari, Pankaj Jain, Zhipeng Zhang, Zhong Jin, Jian He, Suhua Li, Claudio Mapelli, Michael M. Miller, Michael A. Poss, Paul M. Scola, Kap-Sun Yeung, Jin-Quan Yu*. "Ligand-Enabled beta-C-H Arylation of alpha-Amino Acids Using a Simple and Practical Auxiliary" J. Am. Chem. Soc. 2015, 137, 3338. Gang Chen, Zhe Zhuang, Gen-Cheng Li, Tyler G. Saint-Denis, Yi Xiao, Candice L. Joe, Jin-Quan Yu*. "Ligand-Enabled β-C–H Arylation of α-Amino Acids without Installing Exogenous Directing Groups" Angew. Chem. Int. Ed. 2017, 56, 1506. Yun-Fang Yang, Gang Chen, Xin Hong, Jin-Quan Yu and K. N. Houk. "The Origins of Dramatic Differences in Five-Membered vs Six-Membered Chelation of Pd(II) on Efficiency of C(sp3)-H Bond Activation" J. Am. Chem. Soc. 2017, 139, 8514. Suhua Li, Gang Chen, Chen-Guo Feng, Wei Gong, Jin-Quan Yu*. "Ligand-enabled gamma-C-H Olefination and Carbonylation: Construction of beta-Quaternary Carbon Centers" J. Am. Chem. Soc. 2014, 136, 5267. Dajian Zhu, Guoqiang Yang, Jian He, Ling Chu, Gang Chen, Wei Gong, Ke Chen, Martin D. Eastgate, Jin-Quan Yu*. "Ligand-Promoted ortho-C-H Amination with Pd Catalysts" Angew. Chem. Int. Ed. 2015, 54, 2497. Jian He, Heng Jiang, Ryosuke Takise, Ru-Yi Zhu, Gang Chen, Hui-Xiong Dai, T. G. Murali Dhar, Jun Shi, Hao Zhang, Peter T. W. Cheng, Jin-Quan Yu*. "Ligand-Promoted Borylation of C(sp3)-H Bonds with Pd(II) Catalysts." Angew. Chem. Int. Ed. 2016, 55, 785. Kai-Jiong Xiao, Ling Chu, Gang Chen, Jin-Quan Yu. "Kinetic Resolution of Benzylamines via Palladium(II)-Catalyzed C-H Cross-Coupling" J. Am. Chem. Soc. 2016, 138, 7796. Gang Chen, Hongguang Xia, Yu Cai, Dawei Ma*, Junying Yuan*, Chengye Yuan*. "Diphenylbutylpiperidine-based cell autophagy inducers: Design, synthesis and SAR studies". MedChemCommun, 2011, 2, 315. Gang Chen, Hongguang Xia, Yu Cai, Dawei Ma*, Junying Yuan*, Chengye Yuan*. "Synthesis and SAR study of diphenylbutylpiperidines as cell autophagy inducers". Bioorg. Med. Chem. Lett., 2011, 21, 234. Hong-Guang Xia, Lihong Zhang, Gang Chen, Tao Zhang, Junli Liu, Mingzhi Jin, Xiuquan Ma, Dawei Ma*, Junying Yuan*. "Control of basal autophagy by calpain1 mediated cleavage of ATG5". Autophagy, 2010, 6, 1.