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Luo, Y.; Cao, B.; Zhong, M.; Liu, M.; Xiong, X.; Zou, T.*, Organogold(III) Complexes Display Conditional Photoactivities: Evolving From Photodynamic into Photoactivated Chemotherapy in Response to O2 Consumption for Robust Cancer Therapy. Angew. Chem. Int. Ed. 2022, e202212689.
Xiong, X.†; Huang, K.-B.†; Wang, Y.†; Cao, B.; Luo, Y.; Chen, H.; Yang, Y.; Long, Y.; Liu, M.; Chan, A. S. C.; Liang, H.*; Zou, T.*, Target Profiling of an Iridium(III)-based Immunogenic Cell Death Inducer Unveils the Engagement of Unfolded Protein Response Regulator BiP. J. Am. Chem. Soc., 2022, 144, 10407-10416..
Jiang, J.†; Cao, B.†; Chen, Y.†; Luo, H.; Xue, J.; Xiong, X.; Zou, T.*, Alkylgold(III) Complexes Undergo Unprecedented Photo-Induced β-Hydride Elimination and Reduction for Targeted Cancer Therapy. Angew. Chem. Int. Ed. 2022, 61, e202201103.
Xiong, X.; Liu, L.-Y.; Mao, Z.-W.*; Zou, T.* Approaches towards understanding the mechanism-of-action of metallodrugs. Coord. Chem. Rev. 2022, 453, 214311.
Long, Y.†; Cao, B.†; Xiong, X.; Chan, A. S. C.; Sun, R. W.-Y.; Zou, T.*, Bioorthogonal Activation of Dual Catalytic and Anti-Cancer Activities of Organogold(I) Complexes in Living Systems. Angew. Chem. Int. Ed. 2021, 60, 4133-4141. (Hot Paper)
Luo, H.; Cao, B.; Chan, A. S. C.; Sun, R. W.-Y.; Zou, T.*, Cyclometalated Gold(III)-Hydride Complexes Exhibit Visible Light-Induced Thiol Reactivity and Act as Potent Photo-Activated Anti-Cancer Agents. Angew. Chem. Int. Ed. 2020, 59, 11046-11052. (Hot Paper, highlighted as inside back cover)
Zou, T.;† Lok, C.-N.,† Wan, P.-K., Zhang, Z.-F., Fung, S.-K., Che, C.-M.* Anticancer Metal N-Heterocyclic carbene complexes of gold, platinum and palladium, Curr. Opin. Chem. Biol., 2018, 43, 30-36.
Fung, S. K.;† Zou, T.;† Cao, B.; Lee, P.-Y.; Fung, Y. M. E.; Hu, D.; Lok, C.-N.; Che, C.-M.*, Cyclometallated Gold(III) Complexes Containing N-Heterocyclic Carbene Ligands Engage Multiple Anti-Cancer Molecular Targets, Angew. Chem. Int. Ed. 2017, 56, 3892-3896. (Very Important Paper).
Fung, S. K.;† Zou, T.;† Cao, B.; Chen, T.; To, W.-P.; Yang, C.; Lok, C.-N.; Che, C.-M.*, Luminescent platinum(II) complexes with functionalized N-heterocyclic carbene or diphosphine selectively probe mismatched and abasic DNA, Nat. Commun. 2016, 7, 10655.
Zou, T.; Lum, C. T.; Lok, C.-N.; Zhang, J.-J.; Che, C.-M.*, Chemical biology of anticancer gold(III) and gold(I) complexes. Chem. Soc. Rev. 2015, 44, 8786-8801 (Outside Front Cover).
Tsai, J. L.-L.;† Zou, T.;† Liu, J.; Chen, T.; Chan, A. O.-Y.; Yang, C.; Lok, C.-N.; Che, C.-M.*, Luminescent platinum(ii) complexes with self-assembly and anti-cancer properties: hydrogel, pH dependent emission color and sustained-release properties under physiological conditions. Chem. Sci. 2015, 6, 3823-3830.
Zou, T.; Lum, C. T.; Lok, C.-N.; To, W.-P.; Low, K.-H.; Che, C.-M.*, A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N-Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Inhibits Tumor Growth and Angiogenesis In Vivo. Angew. Chem. Int. Ed. 2014, 53, 5810-5814.
Zou, T.;† Liu, J.;† Lum, C. T.; Ma, C.; Chan, R. C.-T.; Lok, C.-N.; Kwok, W.-M.; Che, C.-M.*, Luminescent Cyclometalated Platinum(II) Complex Forms Emissive Intercalating Adducts with Double Stranded DNA and RNA: Differential Emissions and Anticancer Activities. Angew. Chem. Int. Ed. 2014, 53, 10119-10123.
Lok, C.-N.;† Zou, T.;† Zhang, J.-J.; Lin, I. W.-S.; Che, C.-M.*, Controlled-Release Systems for Metal-Based Nanomedicine: Encapsulated/Self-Assembled Nanoparticles of Anticancer Gold(III)/Platinum(II) Complexes and Antimicrobial Silver Nanoparticles. Adv. Mater. 2014, 26, 5550-5557.
Zou, T.; Lum, C. T.; Chui, S. S.-Y.; Che, C.-M.*, Gold(III) Complexes Containing N-Heterocyclic Carbene Ligands: Thiol “Switch-on” Fluorescent Probes and Anti-Cancer Agents. Angew. Chem. Int. Ed. 2013, 52, 2930-2933 (Very Important Paper)
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