Ritter, Tobias - Max-Planck-Institut für Kohlenforschung -

个人简介

2018 - 2020 Managing Director, Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany since 2015 Director at the Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany 2015 - 2017 Visiting Professor, Harvard University, Cambridge, USA 2012 - 2015 Professor of Chemistry and Chemical Biology, Harvard University, Cambridge, USA since 2011 Co-founder SciFluor Life Sciences, now OcuTerra Therapeutics, Boston, USA since 2010 Chemist at the Massachusetts General Hospital, Boston, USA 2010 - 2012 Associate Professor for Chemistry and Chemical Biology, Harvard University, Cambridge, USA 2006 - 2010 Assistant Professor of Chemistry and Chemical Biology, Harvard University, Cambridge, USA 2004 - 2006 Post-Doctoral Fellow, California Institute of Technology, Pasadena, USA 2004 Ph.D. Organic Chemistry, ETH Zürich, Schweiz 1999 Master of Science, Technische Universität Braunschweig, Germany 1975 born in Lübeck, Germany

研究领域

Research in the Ritter group focuses on the development of novel reaction chemistry. We seek to discover molecular structure and reactivity that can contribute to interdisciplinary solutions for challenges in science. The lab focuses on synthetic organic and organometallic chemistry, complex molecule synthesis, and mechanistic studies to develop practical access to molecules of interest in catalysis, medicine, and materials.

近期论文

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Berger, F.; Ritter, T. Site-Selective Late-Stage C–H Functionalization Via Thianthrenium Salts. Synlett 2022, 33, 339–345. Zhang, L.; Ritter, T. A Perspective on Late-Stage Aromatic C–H Bond Functionalization. Journal of the American Chemical Society 2022, 144, 2399–2414. Zhao, D.; Petzold, R.; Yan, J.; Muri, D.; Ritter, T. Tritiation of Aryl Thianthrenium Salts with a Molecular Palladium Catalyst. Nature 2021, 600, 444–449. Su, W.; Xu, P.; Ritter, T. Decarboxylative Hydroxylation of Benzoic Acids. Angewandte Chemie International Edition 2021, 60, 24012–24017. Halder, R.; Ritter, T. 18F-Fluorination: Challenge and Opportunity for Organic Chemists. The Journal of Organic Chemistry 2021, 86, 13873–13884. Juliá, F.; Shao, Q.; Duan, M.; Plutschack, M. B.; Berger, F.; Mateos, J.; Lu, C.; Xue, X.-S.; Houk, K. N.; Ritter, T. High Site Selectivity in Electrophilic Aromatic Substitutions: Mechanism of C–H Thianthrenation. Journal of the American Chemical Society 2021, 143, 16041–16054. Juliá, F.; Yan, J.; Paulus, F.; Ritter, T. Vinyl Thianthrenium Tetrafluoroborate: A Practical and Versatile Vinylating Reagent Made from Ethylene. Journal of the American Chemical Society 2021, 143, 12992–12998. Alvarez, E. M.; Karl, T.; Berger, F.; Torkowski, L.; Ritter, T. Late‐Stage Heteroarylation of Hetero(Aryl)Sulfonium Salts Activated by α‐Amino Alkyl Radicals. Angewandte Chemie International Edition 2021, 60, 13609–13613. Lansbergen, B.; Granatino, P.; Ritter, T. Site-Selective C–H Alkylation of Complex Arenes by a Two-Step Aryl Thianthrenation-Reductive Alkylation Sequence. Journal of the American Chemical Society 2021, 143, 7909–7914. Jia, H.; Häring, A. P.; Berger, F.; Zhang, L.; Ritter, T. Trifluoromethyl Thianthrenium Triflate: A Readily Available Trifluoromethylating Reagent with Formal CF3+, CF3•, and CF3– Reactivity. Journal of the American Chemical Society 2021, 143, 7623–7628. Sun, X.; Ritter, T. Decarboxylative Polyfluoroarylation of Alkylcarboxylic Acids. Angewandte Chemie International Edition 2021, 60, 10557–10562. Xu, P.; López-Rojas, P.; Ritter, T. Radical Decarboxylative Carbometalation of Benzoic Acids: A Solution to Aromatic Decarboxylative Fluorination. Journal of the American Chemical Society 2021, 143, 5349–5354. Cheng, Q.; Chen, J.; Lin, S.; Ritter, T. Allylic Amination of Alkenes with Iminothianthrenes to Afford Alkyl Allylamines. Journal of the American Chemical Society 2020, 142, 17287–17293. Börgel, J.; Ritter, T. Late-Stage Functionalization. Chem 2020, 6, 1877–1887. Berger, F.; Alvarez, E. M.; Frank, N.; Bohdan, K.; Kondratiuk, M.; Torkowski, L.; Engl, P. S.; Barletta, J.; Ritter, T. Cine-Substitutions at Five-Membered Hetarenes Enabled by Sulfonium Salts. Organic Letters 2020, 22, 5671–5674. Alvarez, E. M.; Plutschack, M. B.; Berger, F.; Ritter, T. Site-Selective C–H Functionalization–Sulfination Sequence to Access Aryl Sulfonamides. Organic Letters 2020, 22, 4593–4596. Clemente, G. S.; Rickmeier, J.; Antunes, I. F.; Zarganes-Tzitzikas, T.; Dömling, A.; Ritter, T.; Elsinga, P. H. [18F]Atorvastatin: Synthesis of a Potential Molecular Imaging Tool for the Assessment of Statin-Related Mechanisms of Action. EJNMMI Research 2020, 10. Chen, J.; Li, J.; Plutschack, M. B.; Berger, F.; Ritter, T. Regio‐ and Stereoselective Thianthrenation of Olefins To Access Versatile Alkenyl Electrophiles. Angewandte Chemie, International Edition 2020, 59, 5616–5620. Xu, P.; Zhao, D.; Berger, F.; Hamad, A.; Rickmeier, J.; Petzold, R.; Kondratiuk, M.; Bohdan, K.; Ritter, T. Site‐Selective Late‐Stage Aromatic [18F]Fluorination Via Aryl Sulfonium Salts. Angewandte Chemie, International Edition 2020, 59, 1956–1960. Li, J.; Chen, J.; Sang, R.; Ham, W.-S.; Plutschack, M. B.; Berger, F.; Chabbra, S.; Schnegg, A.; Genicot, C.; Ritter, T. Photoredox Catalysis with Aryl Sulfonium Salts Enables Site-Selective Late-Stage Fluorination. Nature Chemistry 2020, 12, 56–62.