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胡文浩 教授 收藏
中山大学     中国医药科学学院
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个人简介

1995-1998年:香港理工大学应用生物及化学科技学系 博士学位 1987-1990年:中国科学院成都有机化学研究所 硕士学位 1983-1987年:四川大学化学系 学士学位 工作经历 2016.08-至今:中山大学药学院教授;中山大学药学院院长; 2006-2016:华东师范大学化学系教授;上海市高校“东方学者” 特聘教授(2009-);华东师范大学小分子药物研究所所长(2010-2011);上海分子治疗与新药创制工程技术研究中心主任(2011-2016); 2003-2006年:美国施贵宝制药公司,高级研究员(制药工艺),美国新泽西; 2002-2003年:美国GeneSoft制药公司,研究员(药物化学),美国旧金山; 1998-2001年:美国亚利桑那大学化学系博士后; 1993-1998年:中国科学院成都有机化学研究所先后任实习研究员(1990),助理研究员(1993),副研究员(1997)。不对称合成联合开放实验室副主任(1992),课题组长(1992),其间公派到香港理工大学攻读博士学位。

近期论文

Jian-Bei Xi, Ming-Liang Ma, and Wenhao Hu*, Rh2(OAc)4 and InCl3 co-catalyzed diastereoselective trapping of carbamate ammonium ylides with aldehydes for the synthesis of β-hydroxyl-α-amino acid derivatives, Tetrahedron 2016, 72, 579-583. Mingfeng Li, Xin Guo, Weifeng Jin,Qing Zheng, Shunying Liu,* and Wenhao Hu*, Enantioselective Three-component Reaction of Diazoacetates with Indoles and Enals by Iridium/Iminium Co-catalysis, Chem. Commun. 2016, 52, 2736-2739. Jiuwei Che, Dong Xing,* and Wenhao Hu*, Metal-Catalyzed Cross-Coupling of Terminal Alkynes with Different Carbene Precursors, Current Organic Chemistry, 2016, 20, 41-60. Min Tang, Yong Wu, Yuan Liu, Maoqiang Cai, Fei Xia, Shunying Liu,* and Wenhao Hu*, One-pot Enantioselective Multi-component Cascade Reactions for Synthesis of Chiral Functionalized Hydro-epoxyisochromenes: A Rapid Access to Molecular Complexity, Acta Chim. Sinica 2016, 74, DOI: 10.6023/A15090627. Changcheng Jing, Dong Xing,* Lixin Gao, Jia Li, and Wenhao Hu*, Divergent Synthesis of Multisubstituted Tetrahydrofurans and Pyrrolidines via Intramolecular Aldol-type Trapping of Onium Ylide Intermediates, Chem. Eur. J. 2015, 21, 19202-19207. Catalytic Asymmetric Four-Component Reaction for the Rapid Construction of 3,3'-Disubstituted 3-Indol-3'-yloxindoles, Changcheng Jing, Dong Xing,* and Wenhao Hu*, Org. Lett. 2015, 17, 4336-4339. Taoda Shi, Xin Guo, Shenghan Teng, and Wenhao Hu*, Pd(II)-catalyzed formal [4+1] cycloaddition reactions of diazoacetates and aryl propargyl alcohols to form 2,5-dihydrofurans, Chem Commun. 2015, 51, 5204-5207. Dan Zhang, Jun Zhou, Fei Xia, Zhenghui Kang, and Wenhao Hu*, Bond cleavage, fragment modification and reassembly in enantioselective three-component reactions, Nat Commun. 2015, 6, 5801. Fengping Lv , Zhi-fang Li, Wenhao Hu*, and Xiaohua Wu*, Small molecules enhance functional O-mannosylation of α-dystroglycan, Bioorg. Med. Chem. 2015, 23, 7661-7670. Divergent Synthesis of Chiral Heterocycles via Sequencing of Enantioselective Three-Component Reactions and One-Pot Subsequent Cyclizations, Min Tang, Dong Xing,* Haoxi Huang, and Wenhao Hu*, Chem Commun. 2015, 51, 10612-10615. Changcheng Jing, Dong Xing,* Chengjin Wang, and Wenhao Hu*, Synthesis of 3-(hydroxymethyl)-3-indol-3'-yloxindoles via Rh(II)-catalyzed three-component reaction of 3-diazooxindoles, indoles and formalin, Tetrahedron 2015, 71, 3597-3602.

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