个人简介

Instructor of Medicine, Associate Bioengineer (2016 - ) Brigham and Women's Hospital Harvard Medical School Cambridge, MA, USA Postdoctoral Research Fellow (2013 - 2016) Brigham and Women's Hospital Harvard Medical School Harvard-MIT Division of Health Sciences and Technology Wyss Institute for Biologically Inspired Engineering Boston/Cambridge, MA, USA Ph.D. (2012 - 2013) The Wallace H. Coulter Department of Biomedical Engineering at Georgia Institute of Technology and Emory University Atlanta, GA, USA M.S./Ph.D. Candidate (2008 - 2011) Department of Biomedical Engineering Washington University in St. Louis St. Louis, MO, USA B.Eng. (2004 - 2008) School of Biological Sciences and Medical Engineering Southeast University Nanjing, Jiangsu, China Biography Dr. Zhang received a B.Eng. in Biomedical Engineering from Southeast University (Nanjing) in 2008, after which he then came to the US and obtained a M.S. in Biomedical Engineering from Washington University in St. Louis (2011) and a Ph.D. in Biomedical Engineering at Georgia Institute of Technology and Emory University School of Medicine (2013), both with Prof. Younan Xia. Dr. Zhang then pursued postdoctoral training in Prof. Ali Khademhosseini's group at Brigham and Women's Hospital, Harvard Medical School, Harvard-MIT Division of Health Sciences and Technologies, and Wyss Institute for Biologically Inspired Engineering. He currently holds a faculty position of Instructor of Medicine and Associate Bioengineer at Brigham and Women's Hospital, Harvard Medical School. His research interests include cancer theranostics, organs-on-a-chip, 3D bioprinting, biomaterials, tissue engineering and regenerative medicine, biomedical imaging, drug delivery, nanomedicine, and developmental biology. At leisure, he enjoys bird- and nature-watching, traveling, photography, and novel technologies. Awards and Honors Biomaterials Outstanding Paper Award, Jul 2017 Future Science Early Career Research Award, Jul 2017 Bioanalysis Zone New Investigator Award, Highly Recommended Award, Jun 2017 Partners HealthCare Innovators Recognition, Apr 2017 Bioanalysis Zone New Investigator Award, Highly Recommended Award, Jun 2017 ACS Nano Kavli Foundation Junior Fellow, Mar 2017 Biotech Specialty Section Outstanding Young Investigator Award, Society of Toxicology, Mar 2017 Finalist, SLAS Innovation Award, Feb 2017 Brigham and Women’s Hospital Department of Medicine Chair’s Research Award, Dec 2016 Rising Star in Oncology, Society for Translational Oncology, Oct 2016 The Lush Prize – Young Researcher (Americas), Sept 2016 American Association of Pharmaceutical Scientists Postdoctoral Award, Aug 2016 National Cancer Institute (NCI) of the National Institutes of Health (NIH) K99//R00 Pathway to Independence Award, May 2016 Finalist, Victor K. LaMer Award, Mar 2016 JALA TEN, Feb 2016 Tissue Engineering Young Investigator Council, Feb 2016 Biomedical Engineering Society (BMES) Cellular and Molecular Bioengineering (CMBE) Fellow Award, Jan 2016 Biomaterials Innovation Research Center (BIRC) Impact Award, Brigham and Women’s Hospital, Oct 2015 Baxter Young Investigator Award, Jul 2015 Brigham and Women’s Hospital Microgrant Award, Center for Faculty Development and Diversity, Jul 2015 Finalist, Bioanalysis Zone Young Investigator Award, May 2015 Brigham and Women’s Hospital Postdoctoral Research Fellow Leadership Award, Center for Faculty Development and Diversity, May 2015 Finalist, Journal of Laboratory Automation (JALA) and Journal of Biomolecular Screening (JBS) Art of Science Contest, Feb 2015 Best Poster Award, Third Prize, 2014 2nd International Translational Nanomedicine Conference (ITNANO), Boston, MA, USA, Jul 2014 Science artwork selected for exhibition, Harvard Integrated Life Sciences (HILS) Gallery “The Subjective Objective: Imaging Biology”, Harvard University, Cambridge, MA, USA, Mar 2014 Honorable Mention, Regenerative Medicine Foundation’s 1st Science Photo Art Contest, “Art of Science: Under the Surface”, USA, Feb 2014 (Artwork on exhibition at Palm Beach Photographic Center on Mar 20th, 2014, and at the Regenerative Medicine Foundation Annual Meeting in San Francisco, May 7–8th, 2014) Anne Robinson Clough Conference Grant, Georgia Institute of Technology, Atlanta, GA, USA, Apr 2013 Chinese Government Award for Outstanding Students Abroad, Apr 2012 Student Travel Award Recognition, Honorable Mention, Society For Biomaterials Annual Meeting and Exposition, Orlando, FL, USA, Apr 2011 Second Prize, Jiangsu Provincial Olympiad for Biology, 2003 First Prize, Tianyuan National Olympiad for Chemistry, 2001

研究领域

Engineering Functional Tissues and Tissue Models Using Advanced Biofabrication Technologies

近期论文

Li Y, Zhu K, Liu X, Zhang YS*. Blood-Vessel-on-a-Chip Platforms for Evaluating Nanoparticle Drug Delivery Systems. Current Drug Metabolism, 2017, in press. Zhang YS*, Oklu R, Albadawi H. Bioengineered in vitro Models of Thrombosis: Methods and Techniques. Cardiovascular Diagnosis & Therapy, 2017, in press. Shaegh SAM, Pourmand A, Nabavinia M, Avic H, Tamayol A, Mostafalu P, Ghavifekr HB, Aghdam EN, Dokmeci MR, Khademhosseini A*, Zhang YS*. Rapid Prototyping of Whole-Thermoplastic Microfluidics with Built-In Microvalves. Sensors and Actuators: B. Chemical, 2017, in press. Mirani B, Pagan E, Currie B, Siddiqui MA, Hosseinzadeh R, Mostafalu P, Zhang YS, Ghahary A, Akbari M. An Advanced Multifunctional Hydrogel-Based Dressing for Wound Monitoring and Drug Delivery. Advanced Healthcare Materials, 2017, in press. Kankala RK, Zhang YS*, Wang S-B, Lee C-H, Chen A-Z*. Supercritical Fluid Technology: An Emphasis on Drug Delivery and Related Biomedical Applications. Advanced Healthcare Materials, 2017, in press. (Featured on the back cover of the journal) Skardal A, Murphy SV, Devarasetty M, Mead I, Kang H-W, Seol Y-J, Zhang YS, Shin SR, Zhang L, Aleman J, Hall AR, Shupe TD, Kleensang A, Dokmeci MR, Lee SJ, Jackson J, Yoo JJ, Hartung T, Khademhosseini A, Soker S, Bishop CE, Atala A. Multi-Tissue Interactions in An Integrated Three-Tissue Organ-on-A-Chip Platform. Scientific Reports, 2017, in press. Frey L, Bandaru P, Zhang YS, O’Kelly K, Khademhosseini A, Shin SR. A Dual-layered Microfluidic Chip for Long-term Controlled in situ Delivery of Multiple Anti-inflammatory Factors for Chronic Neural Applications. Advanced Functional Materials, 2017, in press. Hassan S, Prakash G, Öztürk AB, Saghazadeh S, Sohail MF, Seo J, Dokmeci MR, Zhang YS*, Khademhosseini A*. Evolution and Clinical Translation of Drug Delivery Nanomaterials. Nano Today, 2017, in press. Zhang YS*, Qingmeng Pi, Anne Metje van Genderen. Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids. Journal of Visualized Experiments (JoVE), 2017, in press. Zhang YS, Zhu C, Xia Y. Inverse Opal Scaffolds and Their Biomedical Applications. Advanced Materials, 2017, in press. Zhang YS*, Zhang Y-N, Zhang W*. Cancer-on-a-Chip Systems at the Frontier of Nanomedicine. Drug Discovery Today, 2017, in press. Ju J, Yao X, Hou X, Liu Q, Li Y-C, Zhang YS*, Khademhosseini A*. Highly Stretchable and Robust Non-fluorinated Superhydrophobic Surface. Journal of Materials Chemistry A, 2017, in press. Du J, Zhang YS, Hobson D, Hydbring P. Nanoparticles for Immune System Targeting. Drug Discovery Today, 2017, in press. Massa S, Sakr MA, Seo J, Bandaru P, Arneri A, Bersini S, Zare-Eelanjegh E, Jalilian E, Cha BH, Antona S, Enrico A, Gao Y, Hassan S, Acevedo JP, Dokmeci MR, Zhang YS, Khademhosseini A, Shin SR. Bioprinted 3D Vascularized Liver Tissue Model for Drug Toxicity Screening. Biomicrofluidics, 2017, 11, 044109. Leijten J, Seo J, Yue K, Trujillo-de Santiago G, Tamayol A, Ruiz-Esparza GU, Shin SR, Sharifi R, Noshadi I, Alvarez MM, Zhang YS, Khademhosseini A*. Spatially and Temporally Controlled Hydrogels for Tissue Engineering. Materials Science & Engineering R, 2017, 119, 1-35. (Featured on the front cover of the journal) Chen Y, Fu, G, Zilberman Y, Ruan W, Ameri SK, Zhang YS, Miller E, Sonkusale SR. Low Cost Smart Phone Diagnostics for Food Using Paper-Based Colorimetric Sensor Arrays. Food Control, 2017, 82, 227-232. Yu T-T, Cui F-Z, Meng Q-Y, Wang J, Wu D-C, Zhang J, Kou X-X, Yang R-L, Liu Y, Zhang YS*, Yang F*, Zhou Y-H*. Influence of Surface Chemistry on Adhesion and Osteo/Odontogenic Differentiation of Dental Pulp Stem Cells. ACS Biomaterials Science & Engineering, 2017, 3, 1119-1128. Yue K, Li X, Schrobback K, Sheikhi A, Annabi N, Leijten J, Zhang W, Zhang YS, Hutmacher DW, Klein TJ, Khademhosseini A. Structural Analysis of Photocrosslinkable Methacryloyl-Modified Protein Derivatives. Biomaterials, 2017, 139, 163-171. Liu W, Heinrich MA, Zhou Y, Akpek A, Hu N, Liu X, Zhong Z, Guan X, Jin X, Khademhosseini A*, Zhang YS*. Extrusion Bioprinting of Shear-Thinning Gelatin Methacryloyl Bioinks. Advanced Healthcare Materials, 2017, 6, 1601451. (Featured on the back cover of the journal) Zhang YS, Trujillo-de Santiago G, Alvarez MM, Schiff SJ, Boyden ES, Khademhosseini A. Expansion Mini-Microscopy: An Enabling Alternative in Point-of-Care Diagnostics. Current Opinion in Biomedical Engineering, 2017, 1, 45053.