Zhang, Yu Shrike - Harvard Medical School

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Zhang, Yu Shrike Associate Bioengineer 收藏
Harvard Medical School Department of Medicine
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个人简介

Dr. Zhang currently holds an Assistant Professor position at Harvard Medical School and is an Associate Bioengineer at Brigham and Women's Hospital. His research interests include 3D bioprinting, organ-on-a-chip, biomaterials, regenerative engineering, bioanalysis, nanomedicine, and biology. His scientific contributions have been recognized by >40 international, national, and regional awards. He has been invited to deliver >100 lectures worldwide, and has served as reviewer for >500 manuscripts for >40 journals. He is serving as Editor-in-Chief for Microphysiological Systems, and Associate Editor for Bio-Design and Manufacturing and Essays in Biochemistry. He is also on Editorial Board of Biofabrication, Bioprinting, Advanced Healthcare Materials, BMC Materials, and Chinese Chemical Letters, Editorial Advisory Board of Heliyon, and Advisory Panel of Nanotechnology. Selected Awards and Honors Kidney Precision Medicine Project (KPMP) Consortium Travel Award, Jan 2019 Dutch Kidney Foundation Visiting Scientist, Utrecht University, Dec 2018 Annals of Biomedical Engineering Editor’s Choice Best Paper Award, Oct 2018 IEEE Photonics Society Young Investigator Award, Oct 2018 TERMIS-AM Young Investigator Award, Sept 2018 C&EN Talented 12, American Chemical Society, Aug 2018 Society for Mechanical Engineers Marcus Crotts Outstanding Young Manufacturing Engineer Award, May 2018 Hofvijverkring Visiting Scientist, Regenerative Medicine Program, Utrecht University, Netherlands, Mar 2018 Partners in Excellence Award, Partners Healthcare, Feb 2018 SLAS Tony B. Academic Travel Award, Feb 2018 IEEE Sensors Council Technical Achievement Award (Early Career), Nov 2017 Biomaterials Outstanding Paper Award, Sept 2017 Finalist, Future Science Early Career Research Award, Future Science Group, Jul 2017 Bioanalysis Zone New Investigator Award, Highly Recommended Award, Future Science Group, Jun 2017 Partners HealthCare Innovators Recognition, Apr 2017 ACS Nano Kavli Foundation Junior Fellow, Mar 2017 Biotech Specialty Section Outstanding Young Investigator Award, Society of Toxicology, Mar 2017 Finalist, SLAS Innovation Award, Feb 2017 Brigham and Women’s Hospital Department of Medicine Chair’s Research Award, Dec 2016 Rising Star in Oncology, Society for Translational Oncology, Oct 2016 The Lush Prize—Young Researcher (Americas), Sept 2016 American Association of Pharmaceutical Scientists Postdoctoral Award, Aug 2016 National Institutes of Health (NIH) K99/R00 Pathway to Independence Award, May 2016 Future of Health Technology Project Recognition Award, May 2016 Finalist, Victor K. LaMer Award, Mar 2016 JALA TEN, Feb 2016 Tissue Engineering Young Investigator Council, Feb 2016 Biomedical Engineering Society (BMES) Cellular and Molecular Bioengineering (CMBE) Fellow Award, Jan 2016 Biomaterials Innovation Research Center (BIRC) Impact Award, Brigham and Women’s Hospital, Oct 2015 Baxter Young Investigator Award, Jul 2015 Brigham and Women’s Hospital Microgrant Award, Center for Faculty Development and Diversity, Jul 2015 Finalist, Bioanalysis Zone Young Investigator Award, May 2015 Brigham and Women’s Hospital Postdoctoral Research Fellow Leadership Award, Center for Faculty Development and Diversity, May 2015 Finalist, Journal of Laboratory Automation (JALA) and Journal of Biomolecular Screening (JBS) Art of Science Contest, Feb 2015 Best Poster Award, Third Prize, 2nd International Translational Nanomedicine Conference (ITNANO), Boston, MA, USA, Jul 2014 Science artwork selected for exhibition, Harvard Integrated Life Sciences (HILS) Gallery “The Subjective Objective: Imaging Biology”, Harvard University, Cambridge, MA, USA, Mar 2014 Honorable Mention, Regenerative Medicine Foundation’s 1st Science Photo Art Contest, “Art of Science: Under the Surface”, USA, Feb 2014 Anne Robinson Clough Conference Grant, Georgia Institute of Technology, Atlanta, GA, USA, Apr 2013 Chinese Government Award for Outstanding Students Abroad, Apr 2012 Student Travel Award Recognition, Honorable Mention, Society For Biomaterials Annual Meeting and Exposition, Orlando, FL, USA, Apr 2011 Second Prize, Jiangsu Provincial Biology Olympiad, China, 2003 First Prize, Tianyuan National Chemistry Olympiad, China, 2001

个人简介

Selected Awards and Honors
Kidney Precision Medicine Project (KPMP) Consortium Travel Award, Jan 2019
Dutch Kidney Foundation Visiting Scientist, Utrecht University, Dec 2018
Annals of Biomedical Engineering Editor’s Choice Best Paper Award, Oct 2018
IEEE Photonics Society Young Investigator Award, Oct 2018
TERMIS-AM Young Investigator Award, Sept 2018
C&EN Talented 12, American Chemical Society, Aug 2018
Society for Mechanical Engineers Marcus Crotts Outstanding Young Manufacturing Engineer Award, May 2018
Hofvijverkring Visiting Scientist, Regenerative Medicine Program, Utrecht University, Netherlands, Mar 2018
Partners in Excellence Award, Partners Healthcare, Feb 2018
SLAS Tony B. Academic Travel Award, Feb 2018
IEEE Sensors Council Technical Achievement Award (Early Career), Nov 2017
Biomaterials Outstanding Paper Award, Sept 2017
Finalist, Future Science Early Career Research Award, Future Science Group, Jul 2017
Bioanalysis Zone New Investigator Award, Highly Recommended Award, Future Science Group, Jun 2017
Partners HealthCare Innovators Recognition, Apr 2017
ACS Nano Kavli Foundation Junior Fellow, Mar 2017
Biotech Specialty Section Outstanding Young Investigator Award, Society of Toxicology, Mar 2017
Finalist, SLAS Innovation Award, Feb 2017
Brigham and Women’s Hospital Department of Medicine Chair’s Research Award, Dec 2016
Rising Star in Oncology, Society for Translational Oncology, Oct 2016
The Lush Prize—Young Researcher (Americas), Sept 2016
American Association of Pharmaceutical Scientists Postdoctoral Award, Aug 2016
National Institutes of Health (NIH) K99/R00 Pathway to Independence Award, May 2016
Future of Health Technology Project Recognition Award, May 2016
Finalist, Victor K. LaMer Award, Mar 2016
JALA TEN, Feb 2016
Tissue Engineering Young Investigator Council, Feb 2016
Biomedical Engineering Society (BMES) Cellular and Molecular Bioengineering (CMBE) Fellow Award, Jan 2016
Biomaterials Innovation Research Center (BIRC) Impact Award, Brigham and Women’s Hospital, Oct 2015
Baxter Young Investigator Award, Jul 2015
Brigham and Women’s Hospital Microgrant Award, Center for Faculty Development and Diversity, Jul 2015
Finalist, Bioanalysis Zone Young Investigator Award, May 2015
Brigham and Women’s Hospital Postdoctoral Research Fellow Leadership Award, Center for Faculty Development and Diversity, May 2015
Finalist, Journal of Laboratory Automation (JALA) and Journal of Biomolecular Screening (JBS) Art of Science Contest, Feb 2015
Best Poster Award, Third Prize, 2nd International Translational Nanomedicine Conference (ITNANO), Boston, MA, USA, Jul 2014
Science artwork selected for exhibition, Harvard Integrated Life Sciences (HILS) Gallery “The Subjective Objective: Imaging Biology”, Harvard University, Cambridge, MA, USA, Mar 2014
Honorable Mention, Regenerative Medicine Foundation’s 1st Science Photo Art Contest, “Art of Science: Under the Surface”, USA, Feb 2014
Anne Robinson Clough Conference Grant, Georgia Institute of Technology, Atlanta, GA, USA, Apr 2013
Chinese Government Award for Outstanding Students Abroad, Apr 2012
Student Travel Award Recognition, Honorable Mention, Society For Biomaterials Annual Meeting and Exposition, Orlando, FL, USA, Apr 2011
Second Prize, Jiangsu Provincial Biology Olympiad, China, 2003
First Prize, Tianyuan National Chemistry Olympiad, China, 2001

研究领域

Organs-on-Chips Biomaterials & Biofabrication Bioanalysis Cancer Theranostics

近期论文

Li R, McCarthy A, Zhang YS, Xie J. Decorating 3D Printed Scaffolds with Electrospun Nanofiber Segments for Regenerative Medicine. Advanced Biosystems, 2019, in press. Wang Y, Hu X, Kankala R, Yang D-Y, Zhu K, Wang S-B, Zhang YS*, Chen A-Z*. Endothelialized Microrods for Minimally Invasive in situ Neovascularization. Biofabrication, 2019, in press. Li W, Liu X, Deng Z, Chen Y, Yu Q, Tang W, Sun LT, Zhang YS*, Yue K*. Tough Bonding, on-Demand Debonding, and Facile Rebonding between Hydrogels and Diverse Metal Surfaces. Advanced Materials, 2019, in press. Kazan A, Yesil-Celiktas O, Zhang YS. Fabrication of Thymoquinone-Loaded Albumin Nanoparticles by Microfluidic Particle Synthesis and Their Effect on Planarian Regeneration. Macromomlecular Bioscience, 2019, in press. Trujillo-de Santiago G, Flores-Garza BG, Tavares-Negrete JA, Lara-Mayorga IM, González-Gamboa I, Zhang YS, Rojas-Martínez A, Ortiz-López R, Álvarez MM. The Tumor-on-Chip: Recent Advances in the Development of Microfluidic Systems to Recapitulate the Physiology of Solid Tumors. Materials, 2019, 12, 2945. Wang Y, Kankala RK, Zhu K, Wang S-B, Zhang YS*, Chen A-Z*. Co-Axial Extrusion of Tubular Tissue Constructs Using A Gelatin/GelMA Blend Bioink. ACS Biomaterials Science & Engineering, 2019, 5, 5514-5524. (Featured on the supplementary cover of the journal) Zhang X, Wang Z, Li H, Hou C, Kong X, Zhang YS, Li Q, Song X, Zhao H, Wang L. Modeling and Experimental Investigation of Polymer Micro-Part Demolding from A Zr-Based Bulk Metallic Glass Mold. Polymer Engineering & Science, 2019, in press. Chen N, Zhu K, Zhang YS, Yan S, Pan T, Abudupataer M, Yu G, Alam F, Wang L, Sun X, Yu Y, Wang C, Zhang W. Hydrogel Bioink with Multilayered Interfaces Improves Dispersibility of Encapsulated Cells in Extrusion Bioprinting. ACS Applied Materials & Interfaces, 2019, 11, 30585-30595. Gong J, Sun M, Wang S, He J, Wang Y, Qian Y, Liu Y, Dong L, Ma L, Cheng K, Weng W-J, Yu M*, Zhang YS*, Wang H*. Surface Modification by Divalent Main-Group-Elemental Ions for Improved Bone Remodeling to Instruct Implant Biofabrication. ACS Biomaterials Science & Engineering, 2019, 5, 3311-3324. Duchamp M, Bakht SW, Ju J, Yazdi IK, Zhang W*, Zhang YS*. Perforated and Endothelialized Elastomeric Tubes for Vascular Modeling. Advanced Materials Technologies, 2019, 4, 1800741. (Featured on the front cover of the journal) Cheng F, Cao X, Li H, Liu T, Xie X, Huang D, Maharjan S, Bei HP, Gómez A, Li J, Zhan H, Shen H, Liu S, He J, Zhang YS*. Generation of Cost-Effective Paper-Based Tissue Models through Matrix-Assisted Sacrificial 3D Printing. Nano Letters, 2019, 19, 3603-3611. Deng J, Tang Y, Zhang Q, Luo G, Liao M, Wang C, Ji P, Song J, Chen L, Ran X, Wei Z, Zheng L, Dang R, Liu X, Zhang H*, Zhang YS*, Zhang X*, Tan H. A Bioinspired Medical Adhesive Derived from Skin Secretion of Andrias davidianus for Wound Healing. Advanced Functional Materials, 2019, 29, 1809110. Kankala RK, Zhao J, Liu C-G, Song X-J, Yang D-Y, Zhu K, Wang S-B, Zhang YS*, Chen A-Z*. Highly Porous Microcarriers for Minimally Invasive in situ Skeletal Muscle Cell Delivery. Small, 2019, 15, 1901397. (Featured on the front cover of the journal) Cao X, Ashfaq R, Cheng F, Maharjan S, Li J, Ying G, Hassan S, Xiao H, Yue K, Zhang YS*. A Tumor-on-a-Chip System with Bioprinted Blood and Lymphatic Vessel Pair. Advanced Functional Materials, 2019, 29, 1807173. (Featured on the back cover of the journal) Miri AK, Mirzaee I, Hassan S, Oskui SM, Nieto D, Khademhosseini A*, Zhang YS*. Effective Bioprinting Resolution in Tissue Model Fabrication. Lab on a Chip, 2019, 19, 2019-2037. Duchamp M, Liu T, van Genderen AM, Kappings V, Oklu R, Ellisen LW, Zhang YS*. Sacrificial Bioprinting of A Mammary Ductal Carcinoma Model. Biotechnology Journal, 2019, 14, 1700703. (Featured on the front cover of the journal) Heinrich MA, Liu W, Jimenez A, Yang J, Akpek A, Liu X, Pi Q, Mu X, Hu N, Prakash J, Schiffelers RM, Xie J, Zhang YS*. 3D Bioprinting: from Benches to Translational Applications. Small, 2019, 15, 1805510. (Featured on the back cover of the journal) Lin Q, Huang D*, Du J, Wei Y, Hu Y, Lian X, Xie X, Chen W, Zhang YS*. Nano-Hydroxyapatite Crystal Formation Based on Calcified TiO2 Nanotube Arrays. Applied Surface Science, 2019, 478, 237-246. Xu J, Wang H, Hu Y, Wen L, Yin F, Wang, Z, Zhang Y, Li S, Lin B, Zuo D, Lin J, Zhang T, Zhang YS, Ding J*, Hua Y*, Cai Z*. Inhibition of CaMKIIα Activity Enhances Antitumor Effect of Fullerene C60 Nanocrystals by Suppression of Autophagic Degradation. Advanced Science, 2019, 6, 1801233. (Featured on the back cover of the journal) Heinrich MA, Bansal R, Broekman M, Lammers T, Zhang YS, Schiffelers RM, Prakash J. 3D-Bioprinted Mini-Brain: A Glioblastoma Model to Study Cellular Interactions and Therapeutics. Advanced Materials, 2019, 31, 1806590. (Featured on the frontispiece of the journal)

近期论文

Li R, McCarthy A, Zhang YS, Xie J. Decorating 3D Printed Scaffolds with Electrospun Nanofiber Segments for Regenerative Medicine. Advanced Biosystems, 2019, in press.

Wang Y, Hu X, Kankala R, Yang D-Y, Zhu K, Wang S-B, Zhang YS*, Chen A-Z*. Endothelialized Microrods for Minimally Invasive in situ Neovascularization. Biofabrication, 2019, in press.

Li W, Liu X, Deng Z, Chen Y, Yu Q, Tang W, Sun LT, Zhang YS*, Yue K*. Tough Bonding, on-Demand Debonding, and Facile Rebonding between Hydrogels and Diverse Metal Surfaces. Advanced Materials, 2019, in press.

Kazan A, Yesil-Celiktas O, Zhang YS. Fabrication of Thymoquinone-Loaded Albumin Nanoparticles by Microfluidic Particle Synthesis and Their Effect on Planarian Regeneration. Macromomlecular Bioscience, 2019, in press.

Trujillo-de Santiago G, Flores-Garza BG, Tavares-Negrete JA, Lara-Mayorga IM, González-Gamboa I, Zhang YS, Rojas-Martínez A, Ortiz-López R, Álvarez MM. The Tumor-on-Chip: Recent Advances in the Development of Microfluidic Systems to Recapitulate the Physiology of Solid Tumors. Materials, 2019, 12, 2945.

Wang Y, Kankala RK, Zhu K, Wang S-B, Zhang YS*, Chen A-Z*. Co-Axial Extrusion of Tubular Tissue Constructs Using A Gelatin/GelMA Blend Bioink. ACS Biomaterials Science & Engineering, 2019, 5, 5514-5524. (Featured on the supplementary cover of the journal)

Zhang X, Wang Z, Li H, Hou C, Kong X, Zhang YS, Li Q, Song X, Zhao H, Wang L. Modeling and Experimental Investigation of Polymer Micro-Part Demolding from A Zr-Based Bulk Metallic Glass Mold. Polymer Engineering & Science, 2019, in press.

Chen N, Zhu K, Zhang YS, Yan S, Pan T, Abudupataer M, Yu G, Alam F, Wang L, Sun X, Yu Y, Wang C, Zhang W. Hydrogel Bioink with Multilayered Interfaces Improves Dispersibility of Encapsulated Cells in Extrusion Bioprinting. ACS Applied Materials & Interfaces, 2019, 11, 30585-30595.

Gong J, Sun M, Wang S, He J, Wang Y, Qian Y, Liu Y, Dong L, Ma L, Cheng K, Weng W-J, Yu M*, Zhang YS*, Wang H*. Surface Modification by Divalent Main-Group-Elemental Ions for Improved Bone Remodeling to Instruct Implant Biofabrication. ACS Biomaterials Science & Engineering, 2019, 5, 3311-3324.

Duchamp M, Bakht SW, Ju J, Yazdi IK, Zhang W*, Zhang YS*. Perforated and Endothelialized Elastomeric Tubes for Vascular Modeling. Advanced Materials Technologies, 2019, 4, 1800741. (Featured on the front cover of the journal)

Cheng F, Cao X, Li H, Liu T, Xie X, Huang D, Maharjan S, Bei HP, Gómez A, Li J, Zhan H, Shen H, Liu S, He J, Zhang YS*. Generation of Cost-Effective Paper-Based Tissue Models through Matrix-Assisted Sacrificial 3D Printing. Nano Letters, 2019, 19, 3603-3611.

Deng J, Tang Y, Zhang Q, Luo G, Liao M, Wang C, Ji P, Song J, Chen L, Ran X, Wei Z, Zheng L, Dang R, Liu X, Zhang H*, Zhang YS*, Zhang X*, Tan H. A Bioinspired Medical Adhesive Derived from Skin Secretion of Andrias davidianus for Wound Healing. Advanced Functional Materials, 2019, 29, 1809110.

Kankala RK, Zhao J, Liu C-G, Song X-J, Yang D-Y, Zhu K, Wang S-B, Zhang YS*, Chen A-Z*. Highly Porous Microcarriers for Minimally Invasive in situ Skeletal Muscle Cell Delivery. Small, 2019, 15, 1901397. (Featured on the front cover of the journal)

Cao X, Ashfaq R, Cheng F, Maharjan S, Li J, Ying G, Hassan S, Xiao H, Yue K, Zhang YS*. A Tumor-on-a-Chip System with Bioprinted Blood and Lymphatic Vessel Pair. Advanced Functional Materials, 2019, 29, 1807173. (Featured on the back cover of the journal)

Miri AK, Mirzaee I, Hassan S, Oskui SM, Nieto D, Khademhosseini A*, Zhang YS*. Effective Bioprinting Resolution in Tissue Model Fabrication. Lab on a Chip, 2019, 19, 2019-2037.

Duchamp M, Liu T, van Genderen AM, Kappings V, Oklu R, Ellisen LW, Zhang YS*. Sacrificial Bioprinting of A Mammary Ductal Carcinoma Model. Biotechnology Journal, 2019, 14, 1700703. (Featured on the front cover of the journal)

Heinrich MA, Liu W, Jimenez A, Yang J, Akpek A, Liu X, Pi Q, Mu X, Hu N, Prakash J, Schiffelers RM, Xie J, Zhang YS*. 3D Bioprinting: from Benches to Translational Applications. Small, 2019, 15, 1805510. (Featured on the back cover of the journal)

Lin Q, Huang D*, Du J, Wei Y, Hu Y, Lian X, Xie X, Chen W, Zhang YS*. Nano-Hydroxyapatite Crystal Formation Based on Calcified TiO2 Nanotube Arrays. Applied Surface Science, 2019, 478, 237-246.

Xu J, Wang H, Hu Y, Wen L, Yin F, Wang, Z, Zhang Y, Li S, Lin B, Zuo D, Lin J, Zhang T, Zhang YS, Ding J*, Hua Y*, Cai Z*. Inhibition of CaMKIIα Activity Enhances Antitumor Effect of Fullerene C60 Nanocrystals by Suppression of Autophagic Degradation. Advanced Science, 2019, 6, 1801233. (Featured on the back cover of the journal)

Heinrich MA, Bansal R, Broekman M, Lammers T, Zhang YS, Schiffelers RM, Prakash J. 3D-Bioprinted Mini-Brain: A Glioblastoma Model to Study Cellular Interactions and Therapeutics. Advanced Materials, 2019, 31, 1806590. (Featured on the frontispiece of the journal)