个人简介
教育经历
2011/09 - 2016/06，北京师范大学，脑与认知科学研究院，理学博士，导师：张占军教授
2007/09 - 2011/06，北京邮电大学，计算机学院，工学学士
工作经历
2021-7至今, 北京师范大学, 认知神经科学与学习国家重点实验室，副教授
2016-6至2021-7, 北京师范大学, 认知神经科学与学习国家重点实验室，讲师
2016-6至2018-6, 北京师范大学, 地理学部，师资博士后
研究领域
现任北京师范大学认知神经科学与学习国家重点实验室认知老化与脑健康研究组神经影像研究方向负责人。长期从事认知老化、阿尔兹海默病高危基因及其危险因素的神经机制研究。研究主要结合神经心理测验、神经影像和基因等多种技术方法，针对影响老年人认知能力的积极与消极因素、认知老化的大脑神经机制、老年性痴呆高危基因的遗传-行为-脑的关联研究等课题进行了深入的研究
近期论文
查看导师新发文章
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Brain Network Organization and Aging
The Aging Patterns of Brain Structure, Function, and Energy Metabolism
Specific structuro‐metabolic pattern of thalamic subnuclei in fatal familial insomnia: A PET/MRI imaging study
Lesion Network Mapping for Neurological Deficit in Acute Ischemic Stroke
Visit-to-visit HbA1c variability, dementia, and hippocampal atrophy among adults without diabetes
SORL1 rs1699102 Moderates the Effect of Sex on Language Network
From local properties to brain-wide organization: A review of intraregional temporal features in functional magnetic resonance imaging data
Naoxin'an capsules protect brain function and structure in patients with vascular cognitive impairment
Contributions of early-life cognitive reserve and late-life leisure activity to successful and pathological cognitive aging
Successful or pathological cognitive aging? Converging into a “frontal preservation, temporal impairment (FPTI)” hypothesis
Tau as a biomarker of cognitive impairment and neuropsychiatric symptom in Alzheimer's disease
The characteristics of glucose metabolism and functional connectivity in posterior default network during nondemented aging: relationship with executive function performance
Brain structural and functional anomalies associated with simultanagnosia in patients with posterior cortical atrophy
Spatial Distribution and Hierarchical Clustering of β-Amyloid and Glucose Metabolism in Alzheimer’s Disease
Specific structuro-metabolic pattern of thalamic subnuclei in fatal familial insomnia: A PET/MRI imaging study
Specific Structuro-Metabolic Pattern of Thalamic Subnuclei in Fatal Familial Insomnia: A PET/MRI Imaging Study
Brain mechanisms underlying neuropsychiatric symptoms in Alzheimer’s disease: a systematic review of symptom-general and –specific lesion patterns
Disrupted White Matter Integrity and Cognitive Functions in Amyloid-β Positive Alzheimer’s Disease with Concomitant Lobar Cerebral Microbleeds
Subcortical Hypermetabolism Associated With Cortical Hypometabolism Is a Common Metabolic Pattern in Patients With Anti-Leucine-Rich Glioma-Inactivated 1 Antibody Encephalitis
Disrupted anterior and posterior hippocampal structural networks correlate impaired verbal memory and spatial memory in different subtypes of MCI
Accelerated Brain Aging in Amnestic Mild Cognitive Impairment: Relationships with Individual Cognitive Decline, Risk Factors for Alzheimer Disease and Clinical Progression
Sex Differences in Cortical Morphometry and White Matter Microstructure During Brain Aging and Their Relationships to Cognition
White Matter Integrity Involvement in the Preclinical Stage of Familial Creutzfeldt–Jakob Disease: A Diffusion Tensor Imaging Study
Early prevention of cognitive impairment in the community population: The Beijing Aging Brain Rejuvenation Initiative
Relationship between the disrupted topological efficiency of the structural brain connectome and glucose hypometabolism in normal aging
Community-based Model for Dementia Risk Screening: The Beijing Aging Brain Rejuvenation Initiative (BABRI) Brain Health System
Metabolic Changes Detected by 18F-FDG PET in the Preclinical Stage of Familial Creutzfeldt-Jakob Disease
APOE ε4 allele accelerates age-related multi-cognitive decline and white matter damage in non-demented elderly
Practicality of promoting brain health and early dementia screening in elderly residents with friendly mobile App: Beijing plan
Age-Related Decline in the Topological Efficiency of the Brain Structural Connectome and Cognitive Aging
Severity of white matter hyperintensities: Lesion patterns, cognition, and microstructural changes
White Matter Microstructural Change Contributes to Worse Cognitive Function in Type 2 Diabetes Mellitus Patients
The positive impacts of early-life education on cognition, leisure activity, and brain structure in healthy aging
COMT VAL158MET AND WORKING MEMORY: MAIN EFFECTS AND INTERACTION WITH GENDER
THE CUMULATIVE SPATIAL DISTRIBUTION OF WHITE MATTER HYPERINTENSITIES AND ITS CRITICAL STAGE THAT AFFECTS COGNITION AND THE BRAIN IN NON-DEMENTED ELDERLY
Basal Ganglia-Cortical Circuit Disruption in Subcortical Silent Lacunar InfarctsTable_1.DOCX
Accelerating Structural Degeneration in Temporal Regions and Their Effects on Cognition in Aging of MCI Patients
The Contribution of Genetic Factors to Cognitive Impairment and Dementia: Apolipoprotein E Gene, Gene Interactions, and Polygenic Risk
Increased intrinsic connectivity for structural atrophy and functional maintenance after acute ischemic stroke
Brain Network Connectivity Mediates Education-related Cognitive Performance in Healthy Elderly Adults
The Relationship between Cerebral White Matter Integrity and Cognitive Function in Mild Stroke with Basal Ganglia Region Infarcts
APOE influences working memory in non-demented elderly through an interaction with SPON1 rs2618516
The Interactive Effects of Age and PICALM rs541458 Polymorphism on Cognitive Performance, Brain Structure, and Function in Non-demented Elderly
The positive effects of Xueshuan Xinmai tablets on brain functional connectivity in acute ischemic stroke: A placebo controlled randomized trial
Disrupted Brain Structural Connectivity: Pathological Interactions Between Genetic APOE ε4 Status and Developed MCI Condition
Inflection Point in Course of Mild Cognitive Impairment: Increased Functional Connectivity of Default Mode Network
Default Mode Network Connectivity and Related White Matter Disruption in Type 2 Diabetes Mellitus Patients Concurrent with Amnestic Mild Cognitive Impairment
Precuneus degeneration in nondemented elderly individuals with APOE ?4: Evidence from structural and functional MRI analyses
Dysfunctional organization of default mode network before memory impairments in type 2 diabetes
Is there a significant interaction effect between apolipoprotein E rs405509 T/T and ε4 genotypes on cognitive impairment and gray matter volume?
Disrupted White Matter Network and Cognitive Decline in Type 2 Diabetes Patients
The TT allele of rs405509 synergizes with APOE ε4 in the impairment of cognition and its underlying default mode network in non-demented elderly
Selectively Disrupted Functional Connectivity Networks in Type 2 Diabetes Mellitus
Disrupted white matter structure underlies cognitive deficit in hypertensive patients
Association of White Matter Integrity and Cognitive Functions in Chinese Non-Demented Elderly with the APOE?4 Allele
Effects of APOE promoter polymorphism on the topological organization of brain structural connectome in nondemented elderly
Disrupted Frontoparietal Network Mediates White Matter Structure Dysfunction Associated with Cognitive Decline in Hypertension Patients
Aberrant White Matter Networks Mediate Cognitive Impairment in Patients with Silent Lacunar Infarcts in Basal Ganglia Territory
Association of White Matter Integrity and Cognitive Functions in Patients With Subcortical Silent Lacunar Infarcts
Disrupted Functional Connectivity Related to Differential Degeneration of the Cingulum Bundle in Mild Cognitive Impairment Patients
The Effects of an APOE Promoter Polymorphism on Human Cortical Morphology during Nondemented Aging
Altered Brain Activation Patterns Under Different Working Memory Loads in Patients With Type 2 Diabetes
Disrupted Functional and Structural Networks in Cognitively Normal Elderly Subjects with the APOE ?4 Allele
Structural and Functional Brain Changes in the Default Mode Network in Subtypes of Amnestic Mild Cognitive Impairment
Aberrant Functional Networks Connectivity and Structural Atrophy in Silent Lacunar Infarcts: Relationship with Cognitive Impairments
The effects of CCRC on cognition and brain activity in aMCI patients: A pilot placebo controlled BOLD fMRI study
Aggravated Cognitive and Brain Functional Impairment in Mild Cognitive Impairment Patients with Type 2 Diabetes: A Resting-State Functional MRI Study
Early Frontal Structural and Functional Changes in Mild White Matter Lesions Relevant to Cognitive Decline
Prevalence of and Potential Risk Factors for Mild Cognitive Impairment in Community-Dwelling Residents of Beijing
Differences in Functional Brain Activation and Hippocampal Volume Among Amnestic Mild Cognitive Impairment Subtypes
Prevalence and predictors of mild cognitive impairment in old age: Results from the BABRI Study
Reduced Frontal Activation during a Working Memory Task in Mild Cognitive Impairment: A Non-Invasive Near-Infrared Spectroscopy Study
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