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个人简介

Professor, Department of Food Science & Technology, National University of Singapore, Singapore, 2022-Present Associate Professor, Department of Food Science & Technology, National University of Singapore, Singapore, 2010-2021 Senior Principal Investigator National University of Singapore (Suzhou) Research Institute (NUSRI), 2013-present Visiting Professor, Technical University of Munich, 2020 Acting Director, Food Science and Technology Programme, National University of Singapore, 2014-2015 Visiting Professor, Chiang Mai University, Thailand, 2015 Visiting Scholar, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, 2011 Acting Director, Food Science and Technology Programme, National University of Singapore, 2009-2010 Principal Research Scientist, Brunswick Laboratories, 2001-2004 Postdoctoral Associate, Massachusetts Institute of Technology, USA, 1999-2001 Doctor of Philosophy (Inorganic Chemistry with minor in Organic Chemistry), Indiana University, Bloomington, USA, 1994-1999 Research Associate, Chengdu Institute of Organic Chemistry (China), 1990-1994 Master of Science (Organic Chemistry), Chinese Academy of Sciences, Lanzhou, China, 1987-1990 Bachelor of Science (Chemistry), Fujian Normal University, Fuzhou, China, 1983-1987

研究领域

Chemical principles of food bioactive constituents including dietary antioxidants, starch hydrolase inhibitors, induced phytoalexins, proanthocyanidins, natural products with anti-aging property, functional food for controlling postprandial hyperglycemia. Dietary organosulfides as slow H2S donors for health promotion. Luminescent molecular and nanoprobes for sensing of reactive oxygen species of biological and environmental concerns (NO2, NO, SO2, ClO-, H2O2, 1O2) Plant proteins as biomaterials for 3D bioprinting of scaffolds for 3D cell culture and biomedical applications

近期论文

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Lu Y, Wang X, Pu H, Lin Y, Li D, Liu SQ, Huang D. 2020. Moringin and Its Structural Analogues as Slow H2S Donors: Their Mechanisms and Bioactivity. Journal of Agriculture and Food Chemistry. 68(27):7235-7245. Zhou F, Guo J, Han X, Gao Y, Chen Q, Huang W, Zhan J, Huang D, You Y. 2020. Cranberry Polyphenolic Extract Exhibits an Antiobesity Effect on High-Fat Diet-Fed Mice through Increased Thermogenesis. The Journal of Nutrition. 150(8):2131-2138 Zhang Y, Yang X, Tang H, Liang D, Wu J, Huang D. 2020. Pyrenediones as versatile photocatalysts for oxygenation reactions with: In situ generation of hydrogen peroxide under visible light. Green Chemistry. 22(1):22-27. Lin Y, Yang X, Lu Y, Liang D, Huang D. 2019. Isothiocyanates as H2S Donors Triggered by Cysteine: Reaction Mechanism and Structure and Activity Relationship. Organic Letters. 21(15):5977-5980. Yang X, Wang T, Guo J, Sun M, Wong MW, Huang D. 2019. Dietary Flavonoids Scavenge Hypochlorous Acid via Chlorination on A- and C-Rings as Primary Reaction Sites: Structure and Reactivity Relationship. Journal of Agriculture and Food Chemistry. 67(15):4346-4354. Sun M, Yang X, Zhang Y, Wang S, Wong MW, Ni R, Huang D. 2019. Rapid and Visual Detection and Quantitation of Ethylene Released from Ripening Fruits: The New Use of Grubbs Catalyst. Journal of Agriculture and Food Chemistry. 67(1):507-513. Liang D, Zhang Y, Wu Z, Chen YJ, Yang X, Sun M, Ni R, Bian J, Huang D. 2018. A near infrared singlet oxygen probe and its applications in in vivo imaging and measurement of singlet oxygen quenching activity of flavonoids. Sensors and Actuators B-Chemical. 266:645-654. Jing L, Wang X, Liu H, Lu Y, Bian J, Sun J, Huang D. 2018. Zein Increases the Cytoaffinity and Biodegradability of Scaffolds 3D-Printed with Zein and Poly(epsilon-caprolactone) Composite Ink. ACS Applied Materials & Interfaces. 10(22):18551-18559 Lehnhardt F, Liang D, Chen Q, Tocmo R, Rychlik M, Huang D. 2017. Effects of S-allyl glutathione disulphide and vinyl-dithiin isomers from garlic on the chronological lifespan of Saccharomyces cerevisiae. Journal of Functional Foods. 37:650-657. Liang D, Bian J, Deng L-W, Huang D. 2017. Cyclic polysulphide 1,2,4-trithiolane from stinky bean (Parkia speciosa seeds) is a slow releasing hydrogen sulphide (H2S) donor. Journal of Functional Foods. 35:197-204. Tocmo R, Liang D, Lin Y, Huang D. 2015. Chemical and Biochemical Mechanisms Underlying the Cardioprotective Roles of Dietary Organopolysulfides. Frontiers in Nutrition. 2 Yan Y, Krishnakumar S, Yu H, Ramishetti S, Deng L-W, Wang S, Huang L, Huang D. 2013. Nickel(II) Dithiocarbamate Complexes Containing Sulforhodamine B as Fluorescent Probes for Selective Detection of Nitrogen Dioxide. Journal of the American Chemical Society. 135(14):5312-5315. Quek Y-L, Tan C-H, Bian J, Huang D. 2011. Air Oxidation of HS- Catalyzed by An Mixed-Valence Diruthenium Complex, an Near-IR Probe for HS- Detection. Inorganic Chemistry. 50(16):7379-7381.

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