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Sibanda BL, Chirgadze DY, Blundell TL. (2010) Crystal structure of DNA--PKcs reveals a large open--ring cradle comprised of HEAT repeats. Nature. 463: 118--21. Worth CL, Gong S, Blundell TL. (2009) Structural and functional constraints in the evolution of protein families. Nat Rev Mol Cell Biol. 10: 709-20. Murray CW, Blundell TL. (2010) Structural biology in fragment--based drug design. Curr Opin Struct Biol. 20: 497–507