Jin, Dayong - University of Technology Sydney - School of Mathematical and Physical Sciences

个人简介

Dayong Jin is a Clarivate Highly Cited Researcher, one of the world’s top 0.1% influential researchers across multiple fields. He has spent the past decade driving the transformation of photonics and materials into analytical, diagnostic and imaging devices for disease detection, including cancer. These devices use photonics technologies to analyse saliva, urine or blood to identify early signs of disease and toxins. His research has been in the physical, engineering and interdisciplinary sciences, with expertise in optics engineering, automation devices, luminescent materials, microscopy imaging, and analytical chemistry, to enable rapid detection of cells and molecules. More recently, Dayong has worked to develop rapid COVID-19 spike-protein tests that allow virus detection from asymptomatic patients. These tests deliver quick results at a reduced cost. This technology builds upon his “Super Dots”, a new family of nanophotonic probes that can up-convert infrared photons into intense visible light at the nanoscale. Several fascinating properties have been discovered since to allow high-throughput bio-discoveries, data storage and high-security-level anti-counterfeiting applications, setting records for the tracking of single-molecule transport, super-resolution microscopy, nanoscale thermometry, and recently optical tweezers. Dayong obtained his PhD from Macquarie University in 2007. At Macquarie, he was promoted to Lecturer in 2010, Senior Lecturer in 2013, Associate Professor in 2014 and Professorial Fellow in 2015. He joined UTS in 2015, as a chair professor, to lead its research in Materials and Technology and to establish the Institute for Biomedical Materials and Devices (IBMD), of which he is the director. Dayong also established the Australian Research Council Industry Transformation Research Hub for Integrated Devices for End-user Analysis at Low Levels (ARC IDEAL Research Hub), the Department of Industry, Science, Energy and Resources’ Australia-China Joint Research Centre for Point of Care Testing (DISER POCT) and recently the UTS-SUSTech Joint Research Centre for Biomedical Materials & Devices. He has also been Chair Professor at Southern University of Science and Technology since 2019. He has won the Australian Museum Eureka Prize (2015), the Australian Academy of Science engineering science medal (2017), the Australian Prime Minister Prize for Science – Physical Scientist of the Year (2017), and the Australian Research Council Laureate Fellowship (2021). He is a fellow of Australian Academy of Technology and Engineering.

研究领域

The ability to detect, quantify, and localise target cells and molecules quickly and with high accuracy and precision is fundamental to many areas of modern biomedical research and industry: from understanding sub-cellular processes and biochemical pathways to early detection in clinical settings.

近期论文

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Six-photon upconverted excitation energy lock-in for ultraviolet-C enhancement. 16 Jul 2021Nature Communications12:1-9Nature Research. Co-authorsSu Q, Wei H-L, Liu Y, Chen C, Guan M, Wang S, Su Y, Wang H, Chen Z, Jin D. 10.1038/S41467-021-24664-X Optical tweezers beyond refractive index mismatch using highly doped upconversion nanoparticles.May 2021Nature Nanotechnology16(5):531-537Nature Research. Co-authorsShan X, Wang F, Wang D, Wen S, Chen C, Di X, Nie P, Liao J, Liu Y, Ding L, Reece PJ, Jin D. 10.1038/S41565-021-00852-0 Axial localization and tracking of self-interference nanoparticles by lateral point spread functions, 1 Apr 2021Nature Communications12:1-9Nature Research. Co-authorsLiu Y, Zhou Z, Wang F, Kewes G, Wen S, Burger S, Ebrahimi Wakiani M, Xi P, Yang J, Yang X, Benson O, Jin D. 10.1038/S41467-021-22283-0 Nanorods with multidimensional optical information beyond the diffraction limit. 19 Nov 2020Nature Communications11:8 pagesNature Research. Co-authorsWen S, Liu Y, Wang F, Lin G, Zhou J, Shi B, Suh YD, Jin D. 10.1038/S41467-020-19952-X High-dimensional super-resolution imaging reveals heterogeneity and dynamics of subcellular lipid membranes.18 Nov 2020Nature communications11(1):10 pages. Co-authorsZhanghao K, Liu W, Li M, Wu Z, Wang X, Chen X, Shan C, Wang H, Chen X, Dai Q, Xi P, Jin D. 10.1038/S41467-020-19747-0 Advances and challenges for fluorescence nanothermometry.Oct 2020Nature methods17(10):967-980. Co-authorsZhou J, Del Rosal B, Jaque D, Uchiyama S, Jin D. 10.1038/S41592-020-0957-Y Single-particle spectroscopy for functional nanomaterials.4 Mar 2020Nature579(7797):41-50. Co-authorsZhou J, Chizhik AI, Chu S, Jin D. 10.1038/S41586-020-2048-8 Future and challenges for hybrid upconversion nanosystems. 1 Dec 2019Nature Photonics13(12):828-838. Co-authorsWen S, Zhou J, Schuck PJ, Suh YD, Schmidt TW, Jin D. 10.1038/S41566-019-0528-X High-sensitivity imaging of time-domain near-infrared light transducer. 1 Aug 2019Nature Photonics13(8):525-531. Co-authorsGu Y, Guo Z, Yuan W, Kong M, Liu Y, Liu Y, Gao Y, Feng W, Wang F, Zhou J, Jin D, Li F. 10.1038/S41566-019-0437-Z Quantitative Lateral Flow Strip Sensor Using Highly Doped Upconversion Nanoparticles.Nov 2018Analytical chemistry90(21):12356-12360. Co-authorsHe H, Liu B, Wen S, Liao J, Lin G, Zhou J, Jin D. 10.1021/ACS.ANALCHEM.8B04330 Multi-photon near-infrared emission saturation nanoscopy using upconversion nanoparticles.17 Aug 2018Nature communications9(1):6 pages. Co-authorsChen C, Wang F, Wen S, Su QP, Wu MCL, Liu Y, Wang B, Li D, Shan X, Kianinia M, Aharonovich I, Toth M, Jackson SP, Xi P, Jin D. 10.1038/S41467-018-05842-W Advances in highly doped upconversion nanoparticles.20 Jun 2018Nature communications9(1):2415. Co-authorsWen S, Zhou J, Zheng K, Bednarkiewicz A, Liu X, Jin D. 10.1038/S41467-018-04813-5 Nanoparticles for super-resolution microscopy and single-molecule tracking.Jun 2018Nature methods15(6):415-423. Co-authorsJin D, Xi P, Wang B, Zhang L, Enderlein J, van Oijen AM. 10.1038/S41592-018-0012-4 Microscopic inspection and tracking of single upconversion nanoparticles in living cells. 6 Apr 2018Light: Science and Applications7(4):6 pages. Co-authorsWang F, Wen S, He H, Wang B, Zhou Z, Shimoni O, Jin D. 10.1038/LSA.2018.7 Activation of the surface dark-layer to enhance upconversion in a thermal field. 1 Mar 2018Nature Photonics12(3):154-158. Co-authorsZhou J, Wen S, Liao J, Clarke C, Tawfik SA, Ren W, Mi C, Wang F, Jin D. 10.1038/S41566-018-0108-5 Amplified stimulated emission in upconversion nanoparticles for super-resolution nanoscopy. 9 Mar 2017Nature543(7644):229-233Nature Publishing Group. Co-authorsLiu Y, Lu Y, Yang X, Zheng X, Wen S, Wang F, Vidal X, Zhao J, Liu D, Zhou Z, Ma C, Zhou J, Piper JA, Xi P, Jin D. 10.1038/NATURE21366 Three-dimensional controlled growth of monodisperse sub-50 nm heterogeneous nanocrystals. 8 Jan 2016Nature Communications7:1-8Nature Publishing Group. Co-authorsLiu D, Xu X, Du Y, Qin X, Zhang Y, Ma C, Wen S, Ren W, Goldys EM, Piper JA, Dou S, Liu X, Jin D. 10.1038/NCOMMS10254 Field-dependent deep learning enables high-throughput whole-cell 3D super-resolution imaging.Mar 2023Nat Methods20(3):459-468. Co-authorsFu S, Shi W, Luo T, He Y, Zhou L, Yang J, Yang Z, Liu J, Liu X, Guo Z, Yang C, Liu C, Huang Z-L, Ries J, Zhang M, Xi P, Jin D, Li Y. 10.1038/S41592-023-01775-5 Thiolate DNAzymes on Gold Nanoparticles for Isothermal Amplification and Detection of Mesothelioma-derived Exosomal PD-L1 mRNA.14 Feb 2023Anal Chem95(6):3228-3237. Co-authorsZhand S, Zhu Y, Nazari H, Sadraeian M, Warkiani ME, Jin D. 10.1021/ACS.ANALCHEM.2C04046 Pixel-Level Classification of Five Histologic Patterns of Lung Adenocarcinoma.7 Feb 2023Anal Chem95(5):2664-2670. Co-authorsShao D, Su F, Zou X, Lu J, Wu S, Tian R, Ran D, Guo Z, Jin D. 10.1021/ACS.ANALCHEM.2C03020