个人简介

B.S. 1986, University of North Dakota (Grand Forks, ND) Ph.D. 1992, Cornell University (Ithaca, NY) Postdoctoral Research Fellow 1992, Bell Laboratories Postdoctoral Research Fellow 1993-95, MIT AWARDS & HONORS (SELECTED) Fellow of the American Chemical Society, 2014 Fellow of National Academy of Inventors, 2013 Common Pathways Award, NJ Association for Biomedical Research, 2013 Sioux Award, University of North Dakota, 2012 Turner Alfrey Visiting Professorship, Dow/Michigan Macromolecular Institute, 2012 POLY Fellow, American Chemical Society, 2012 Finalist, Blavatnik Awards for Young Scientists, New York Academy of Sciences, 2007 Buck-Whitney Award, American Chemical Society, 2005 Thomas Alva Edison Patent Award: Medical/Technology Transfer - New Jersey R&D Council, 2003 Fellow, American Institute for Medical and Biological Engineering, 2003

研究领域

Materials Chemistry/Organic Chemistry

Design and synthesis of novel, degradable polymeric materials The UGroup laboratory centers on polymeric bioactives; specifically, the design of biocompatible, biodegradable polymers that will improve human health. Given that our starting materials are naturally occuring and our polymeric bioactives safe, we incorporate green chemistry approaches to the polymer life-cycle. We engage motivated and creative researchers from chemistry, engineering, biology and pharmacy at all levels - from high school students to visiting scientists from international labs. This diverse and creative research environment leads to many discoveries; we learn the vocabulary of intellectual property (eg, patents) and industrial collaborations as it pertains to our published research in drug delivery.

近期论文

查看导师最新文章 （温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Tao, L; Faig, A; Uhrich, KE "Liposomal Stabilization Using a Sugar-based, PEGylated Amphiphilic Macromolecule", J Coll Interf Sci, 431 (2014) 112–116 10.1016/j.jcis.2014.06.004 Stebbins, ND; Ouimet, MA; Uhrich, KE "Antibiotic-containing polymers for localized, sustained drug delivery", Adv Drug Delivery Rev, (2014) [invited]. 10.1016/j.addr.2014.04.006 Carbone-Howell, AL; Stebbins, N; Uhrich, KE "Poly(anhydride-esters) Comprised Exclusively of Naturally-occurring Antimicrobials and EDTA: Antioxidant and Antibacterial Activities", Biomacromolecules, 15 (5) 1889–1895 (2014). 10.1021/bm500303a Gu, L; Nusblat, LM; Tishbi; N; Noble, SC; Pinson, CM; Mintzer, E; Roth, CM, Uhrich, KE "Cationic Amphiphilic Macromolecule (CAM)-lipid Complexes for Efficient siRNA Gene Silencing", J Control Rel, 184 (28) 28-35 (2014). 10.1016/j.jconrel.2014.04.005 Prudencio, A; Stebbins, ND; Johnson, M; Song, MJ; Langowski, BA; Uhrich, KE "Polymeric Prodrugs of Ampicillin as Antibacterial Coatings", J Bioact Compat Polym, 29 (3) 208-220 (2014). 10.1177/0883911514528410 Abdelhamid, D; Arslan, H, Uhrich, KE "Role of Branching of Hydrophilic Domain on Physicochemical Properties of Amphiphilic Macromolecules", Polym Chem, 5 (4), 1457-1462 (2014) 10.1039/C3PY01072D [invited]. Delgado-Rivera, R; Rosario-Meléndez, R; Yu, W; Uhrich, K "Biodegradable Salicylate-Based Poly(anhydride-ester) Microspheres For Controlled Insulin Delivery", J Biomed Mater Res: A (2013) published online : 24 SEP 2013. 10.1002/jbm.a.34949 PMID: 24027012 PMCID: PMC3952025 Rosario-Melendez, R; Yu, W; Uhrich, K "Biodegradable polyesters containing ibuprofen and naproxen as pendant groups", Biomacromolecules, 14 (10) 3542-3548 (2013). 10.1021/bm400889aPMID: 23957612 Ouimet, MA; Stebbins, ND; Uhrich, KE "Biodegradable Coumaric Acid-based Poly(anhydride-ester) Synthesis and Subsequent Controlled Release", Macromol Rapid Commun, 34 (15) 1231-1236 (2013). link Poree, DE; Zablocki, K; Faig, A; Moghe, PV; Uhrich, KE "Nanoscale Amphiphilic Macromolecules with Variable Lipophilicity and Stereochemistry Modulate Inhibition of Oxidized Low-Density Lipoprotein Uptake", Biomacromolecules, 14 (8) 2463-2469 (2013). link Mitchell, A; Kim, B; Cottrell, J; Engler, S; Witek, L; Ricci, J; Uhrich, KE; O’Connor, JP, "Development of a Guided Bone Regeneration Device using Salicylic Acid-Poly(anhdyrides-ester) Polymer and Osteoconductive Scaffolds", J Biomed Mater Res: Part A (2013); published online: 18 May 2013. link Lewis, DR; Kholokovych, V; Tomasini, MD; Abhelhamid, D; Petersen, LK; Welsh, WJ; Uhrich, KE; Moghe, PV "In Silico Design of Anti-Atherogenic Biomaterials" Biomaterials 34 (32) 7950-7959 (2013). link Wada, K; Yu, W; Elazizi, M; Barakat, S; Ouimet, MA; Rosario-Meléndez, R; Fiorellini, JP; Graves, DT; Uhrich, KE "Impact of Locally Delivered Salicylic Acid from a Poly(anhydride-ester) on Bone Regeneration in Diabetic Rats" J Controlled Release 171 (1) 33-37 (2013). link Ouimet, MA; Griffin, J; Carbone-Howell, AL; Wu, WH; Stebbins, ND; Di, R; Uhrich, KE "Biodegradable Ferulic Acid-containing Poly(anhydride-ester): Degradation Products with Controlled Release and Sustained Antioxidant Activity", Biomacromolecules 14 (3) 854-861 (2013). link