陈峰 - 北京大学 - 海洋研究院

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北京大学工学院终身讲席教授北京大学食品与生物资源工程研究所所长新加坡-北京大学低碳研究中心主任国家“百人计划”获得者教育背景 1993年7月澳大利亚昆士兰大学博士 1990年12月澳大利亚昆士兰大学硕士 1983年7月华南工学院(现华南理工大学) 学士背景资料现任北京大学终身讲席教授、中国食品科技学会功能食品分会常务副理事长兼秘书长，兼任北京大学工学院食品与生物资源工程研究所所长、新加坡-北京大学低碳研究中心主任。陈峰1993年毕业于澳大利亚昆士兰大学化学工程系，获生化工程博士学位，澳大利亚注册工程师。曾任香港大学终身教授兼任植物学系系主任及生物科学学院执行院长。陈峰的研究工作主要集中在微藻生物工程（包括微藻生物能源）、功能食品、生化工程及生物资源工程等领域。陈峰率先提出利用异养方式规模化高密度培养微藻以生产高附加值功能性食品成分及藻类生物能源（例如，脂质），他同时将研究扩展到其它微生物和植物资源的开发及功能性成分研究等领域。迄今已在国际权威学术期刊（SCI）发表250余篇研究论文和综述(SCI引用愈6300次,H-index 43)、专箸4本、美国及中国专利共6项。多次在国际学术会议作大会特邀发言，多次组织国际学术会议。被Essential Science Indicators评为“Highly Cited Scientist”(top 1%)。陈峰还兼任英国皇家化学会期刊Food & Function副主编和另外4个国际学术期刊编委(Process Biochemistry, Journal of Applied Phycology, Biotechnology Letters, Journal of Agricultural and Food Chemistry)。获得荣誉曾获香港大学“杰出青年研究奖”、“杰出研究生导师奖”、“法国-香港联合研究奖”、“首届中国食品科技杰出中青年奖”，2008年被选为“美国医学和生物工程院（AIMBE）院士”，2010年获“美国化学工程师学会大会奖”，2011年被选为“英国皇家化学会会士”，2014年被选为“国际食品科学院院士”。 I. Book 1. Chen, F. & Jiang, Y. (eds) (1999). Microalgal Biotechnology. China Light Industry Press, Beijing, 348 pp. 2. Chen, F. & Jiang Y. (eds) (2001). Algae and their Biotechnological Potential. Kluwer Academic Publishers, Dordrecht, the Netherlands, 316 pp. 3. Chen, F. & Whitton, B. A. (eds) (2001). Special Issue of Journal of Applied Phycology, Vol. 3, No. 4., Kluwer Academic Publishers, Dordrecht, the Netherlands, 110 pp. 4. Chen, F., Li, J.R., Hu, X.S., Liu, X., Meng S.H. & Shao, W. (2002). Modern Biological & Food Technology. China Light Industry Press, Beijing, 304 pp. II. Patents Six patents in total (including Chinese patents and U.S. patents, etc.).

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Full SCI Journal Publication List KEY: * = Corresponding Author (Senior Author). Total citations: >6300; H-index: 43 106. Liu, X.J. & Chen, F. * (2003). Cell differentiation and colony alteration of Nostoc flagelliforme, an edible terrestrial cyanobacterium, in different liquid suspension cultures. Folia Microbiologica, 48 (5), 619-626. 105. Wang, S.B., Hu, Q., Sommerfeld, M. & Chen, F.* (2003). An optimized protocol for isolation of soluble proteins from microalgae by two-dimensional gel electrophoresis analysis. Journal of Applied Phycology, 15, 485-496. 104. Lu, H.T., Jiang, Y. & Chen, F. (2003). Application of high-speed counter-current chromatography to the preparative separation and purification of baicalin from the Chinese medicinal plant Scutellaria baicalensis. Journal of Chromatography A, 1017,117-123. 103. Lai, J.P., He, X.W. & Chen, F. * (2003). Separation and determination of the antitumor drug piritrexim by molecularly imprinted microspheres in high performance liquid chromatography. Analytical and Bioanalytical Chemistry, 377(1), 208-213. 102. Liu, X.J., Chen, F.* & Jiang, Y. (2003). Differentiation of Nostoc flagelliforme , and its neighboring species using , fatty acid profiling as a chemotaxonomic tool. Current Microbiology, 47 (6), 467-474. 101. Wen, Z.Y. & Chen, F. * (2003). Heterotrophic production of eicosapentaenoic acid by microalgae. Biotechnology Advances, 21(4), 273-294. [Invited Article]. 100. Li, X.Z., Dong, X.L., Zhao, C.X., Chen, Z. & Chen, F. (2003). Isolation and some properties of cellulose-degrading Vibrio sp. LX-3 with agar-liquefying ability from soil. World Journal of Microbiology & Biotechnology, 19, 375-379. 99. Lu, H.T., Jiang, Y. & Chen, F. * (2003). Preparative separation and purification of squalene from the microalga Thraustochytrium sp. by high-speed counter-current chromatography. Journal of Chromatography A, 994, 37-43. 98. Lai, J.P., He, X.W., Jiang, Y. & Chen, F. * (2003). Preparative separation and determination of matrine from the Chinese medicinal plant Sophora flavescens Ait by molecularly imprinted solid phase extraction. Analytical and Bioanalytical Chemistry, 375, 264-269. 97. Wen, Z.Y. & Chen, F. * (2002). Perfusion culture of the diatom Nitzschia laevis for ultra-high yield production of eicosapentaenoic acid. Process Biochemistry, 38, 523-529. 96. Zhong, J.J., Pan, Z.W., Wang, Z.Y., Wu, J.Y., Chen, F., Takagi, M. & T. Yoshida (2002). Effect of mixing time on taxoid production in suspension cultures of Taxus chinensis in a centrifugal impeller bioreactor. Journal of Bioscience and Bioengineering, 94 (3), 244-250. 95. Shi, X.M., Jiang, Y. & Chen, F. * (2002). High-yield production of lutein by the green microalga Chlorella protothecoides in heterotrophic fed-batch culture. Biotechnology Progress, 18, 723-727. 94. Wen, Z.Y., Jiang, Y. & Chen, F. * (2002). High cell density culture of the diatom Nitzschia laevis for eicosapentaenoic acid production: fed-batch development. Process Biochemistry, 37, 1447-1453. 93. Li, H.B., Jiang, Y. & Chen, F. * (2002). Isolation and purification of lutein from the microalga Chlorella vulgaris by extraction after separation. Journal of Agricultural and Food Chemistry, 50, 1070-1072. 92. Li, H.B., Lai, J.P., Jiang, Y. & Chen, F. * (2002). Preparative isolation and purification of salvianolic acid B from the Chinese medicinal plant Salvia miltiorrhiza by high-speed counter-current chromatography. Journal of Chromatography A, 943(2), 235-239. 91. Wen, Z.Y. & Chen, F. * (2002). Continuous cultivation of the diatom Nitzschia laevis for eicosapentaenoic acid production: physiological study and process optimization. Biotechnology Progress, 18, 21-28. 90. Yuan, J.P., Chen, F.*, Liu, X. & Li, X.Z. (2002). Carotenoid composition in the green microalga Chlorococcum. Food Chemistry, 76(3), 319-325. 89. Li, H.B. & Chen, F. * (2001). Preparative isolation and purification of salidroside from the Chinese medicinal plant Rhodiola sacchalinensis by high-speed counter-current chromatography. Journal of Chromatography A, 932, 91-95. 88. Fan, W.K., Chen, F., Jones E.B.G. & Vrijmoed L.L.P. (2001). Eicosapentaenoic acid and docosahexaenoic acid production and okara uilizing potential of thraustochytrids. Journal of Industrial Microbiology & Biotechnology. 27(4), 199-202. 87. Wen, Z.Y. & Chen, F. * (2001). A perfusion-cell bleeding strategy for enhancing the productivity of eicosapentaenoic acid in the culture of Nitzschia laevis. Applied Microbiology and Biotechnology, 57, 316-322. 86. Wen, Z.Y. & Chen, F. * (2001). Optimization of nitrogen sources for heterotrophic production of eicosapentaenoic acid by the diatom Nitzschia laevis. Enzyme and Microbial Technology, 29, 341-347. 85. Wen, Z.Y. & Chen, F. * (2001). Application of statistically-based experimental designs for the optimization of eicosapentaenoic acid production by the diatom Nitzschia laevis. Biotechnology and Bioengineering, 75 (2), 159-169. 84. Li, H.B. & Chen, F. * (2001). Simultaneous determination of twelve water- and fat-soluble vitamins by high-performance liquid chromatography with diode array detection. Chromatographia, 54, 270-273. 83. Li, H.B. & Chen, F. * (2001). Preparative isolation and purification of six diterpenoids from the Chinese medicinal plant Salvia miltiorrhiza by high-speed counter-current chromatography. Journal of Chromatography A, 925, 109-114. 82. Li, H.B. & Chen, F. * (2001). Preparative isolation and purification of astaxanthin from the microalga Chlorococcum sp. by high-speed counter-current chromatogaphy. Journal of Chromatography A, 925, 133-137. 81. Yuan, J.P. & Chen, F.* (2001). Indirect photometric ion chromatographic analysis of anions in Haematococcus pluvialis culture media. Biotechnology Letters, 23(10), 757-760. (IF: 1.676) 80. Ma, R.Y.N. & Chen, F. * (2001). Enhanced production of free trans-astaxanthin by oxidative stress in the cultures of the green microalga Chlorococcum sp. Process Biochemistry, 36(12), 1175-1179. 79. Li, H.B., Chen, F. * & Xu, X.R. (2001). Determination of iodide in seawater and urine by size exclusion chromatography with iodine-starch complex. Journal of Chromatography A, 918, 335-339. 78. Li, H.B. & Chen, F. * (2001). Simultaneous determination of nine water-soluble vitamins in pharmaceutical preparations by high-performance liquid chromatography with diode array detection. Journal of Separation Science, 24, 271-274. 77. Yuan, J.P. & Chen, F. * (2001). Kinetics for the reversible isomerization reaction of trans-astaxanthin. Food Chemistry, 73(2), 131-137. 76. Ma, R.Y.N. & Chen, F. * (2001). Induction of astaxanthin formation by reactive oxygen species in mixotrophic culture of Chlorococcum sp. Biotechnology Letters, 23(7), 519-523. 75. Li, H.B., Chen, F. *, Zhang, T.Y., Yang, F.Q. & Xu, G.Q. (2001). Preparative isolation and purification of lutein from the microalga Chlorella vulgaris by high-speed counter-current chromatography. Journal of Chromatography A, 905, 151-155. 74. Li, H.B. & Chen, F. * (2000). Determination of viatmin B12 in pharmaceutical preparations by a highly sensitive fluorimetric method. Fresenius Journal of Analytical Chemistry (changed to Analytical and Bioanalytical Chemistry), 368(8), 836-838. 73. Fan, K.W., Chen, F., Jones, E.B.G. & Vrijmoed, L.L.P. (2000). Utilization of food processing waste by Thraustochytrids. Fungal Diversity, 5, 185-194. 72. Wen, Z.Y. & Chen, F. * (2000). Heterotrophic production of eicosapentaenoic acid by the diatom Nitzschia laevis: effects of silicate and glucose. Journal of Industrial Microbiology and Biotechnology, 25, 218-224. 71. Chen, H., Chen, F. *, Chiu, F.C.K. & Lo, C.M.Y. (2001). The effect of yeast elicitor on the growth and secondary metabolism of hairy root cultures of Salvia miltiorrhiza. Enzyme and Microbiology Technology, 28, 100-105. 70. Vonshak, A., Cheung, S.M. & Chen, F. (2000). Mixotrophic growth modifies the response of Spirulina (Arthrospira) platensis (cyanobacteria) cells to light. Journal of Phycology, 36, 675-679. 69. Li, H.B. & Chen, F. * (2000). A highly sensitive fluorimetric method for the determination of fluoride in biological material with Al 3+-calcein complex. Fresenius Journal of Analytical Chemistry (changed to Analytical and Bioanalytical Chemistry), 5, 501-504. 68. Li, H.B., Chen, F. * & Xu, X.R. (2000). A highly sensitive spectrophotometric method with solid phase extraction for the determination of methylmercury in human hair. Journal of Analytical Toxicology, 24(8), 704-707. 67. Li, H.B., Chen, F. * & Jiang, Y. (2000). Determination of vitamin B12 in multivitamin tablets and fermentation medium by high performance liquid chromatography with fluorescence detection, Journal of Chromatography A, 891(2), 243-247. 66. Jiang, Y. & Chen, F. * (2000). Effects of temperature and temperature shift on docosahexaenoic acid production by the marine microalga Crypthecodinium cohnii. Journal of the American Oil Chemists Society, 77, 613-617. 65. Jiang, Y. & Chen, F. * (2000). Effects of medium glucose concentration and pH on docosahexaenoic acid content of heterotrophic Crypthecodinium cohnii. Process Biochemistry, 35, 1205-1209. 64. Shi, X.M., Zhang, X.W. & Chen, F. * (2000). Heterotrophic production of biomass and lutein by Chlorella protothecoides on various nitrogen sources. Enzyme and Microbial Technology, 27, 312-318. 63. Chen, H. & Chen, F. * (2000). Induction of phytoalexin formation in crown gall and hairy root cultures of Salvia miltiorrhiza by methyl viologen. Biotechnology Letters, 22(8), 715-720. 62. Wen, Z.Y. & Chen, F. * (2000). Production potential of eicosapentaenoic acid by the diatom Nitzschia laevis. Biotechnology Letters, 22(9), 727-733. 61. Li, H.B. & Chen, F. * (2000). Determination of silicate in water by ion exclusion chromatograpghy with conductivity detection. Journal of Chromatography A, 874(1), 143-147. 60. Li, H.B., Chen, F. * & Xu, X.R. (2000). Fluorimetric determination of methylmercury as an ion-association complex with rhodamine B in the presence of iodide. Fresenius Journal of Analytical Chemistry (changed to Analytical and Bioanalytical Chemistry), 367(5), 499-501. 59. Wen, Z.Y., Teng, X.W. & Chen, F. * (2000). A novel perfusion system for hybridoma cell cultures by two step sequential sedimentation. Journal of Biotechnology, 79, 1-11. 58. Chen, H. & Chen, F. * (2000). Effects of yeast elicitor on the growth and secondary metabolism of a high-tanshinone-producing line of the Ti transformed Salvia miltiorrhiza cells in suspension culture. Process Biochemistry, 35, 837-840. 57. Zhang, X.W., Shi, X.M. & Chen, F. * (1999). A kinetic model for lutein production by the green microalga Chlorella protothecoides in heterotrophic culture. Journal of Industrial Microbiology & Biotechnology, 23(6), 503-507. 56. Chen, H. & Chen, F. * (2000). Effect of yeast elicitor on the secondary metabolism of Ti transformed Salvia miltiorrhiza cell suspension cultures. Plant Cell Reports, 19(7), 710-717. 55. Zhong, J.J., Chen, F. & Hu, W.W. (2000). High density cultivation of Panax notoginseng cells in stirred bioreactors for the production of ginseng biomass and ginseng saponin. Process Biochemistry, 35, 491-496. 54. Yuan, J.P. & Chen, F. * (2000). Purification of trans-astaxanthin from a high-yielding astaxanthin ester-producing strain of the microalga Haematococcus pluvialis. Food Chemistry, 68, 443-448. 53. Jiang, Y. & Chen, F. * (1999). Effects of salinity on cell growth and docosahexaenoic acid content of the heterotrophic marine microalga Crypthecodinium cohnii. Journal of Industrial Microbiology & Biotechnology, 23(6), 508-513. 52. Ren, G. & Chen, F. * (2000). Drying of steamed Asian ginseng (Panax ginseng) roots by microwave-hot air combination. Pharmazie, 55(2), 124-128. 51. Ren, G., Zhang, X.W. & Chen, F. * (2000). Predicting colour kinetics during red Asian ginseng (Panax ginseng) preparation. Pharmazie, 55(4), 300-302. 50. Chen, Q., Chen, F. & Li, Z.Y. (1999). Preparation and surfactant properties of amino acid based surfactants. Chinese Chemical Letters, 10(9), 789-792. 49. Zhang X.W., Chen, F. * & Johns, M.R. (1999). Kinetic models for heterotrophic growth of Chlamydomonas reinhardtii in batch and fed-batch cultures. Process Biochemistry, 35, 385-389. 48. Yuan, J.P. & Chen, F. * (1999). Isomerization of trans-astaxanthin in organic solvents. Journal of Agricultural & Food Chemistry, 47, 3656-3660. 47. Zhang, X.W., Gong, X.D. & Chen, F. * (1999). Dynamics and stability analysis of the growth and astaxanthin production system of Haematococcus pluvialis. Journal of Industrial Microbiology & Biotechnology, 23(2), 133-137. 46. Chen, H., Chen, F. *, Zhang, Y.L. & Song, J.Y. (1999). Production of rosmarinic acid and lithospermic acid B in Ti transformed Salvia miltiorrhiza cell suspension cultures. Process Biochemistry, 34, 777-784. 45. Jiang, Y., Chen, F. * & Liang, S.Z. (1999). Production potential of docosahexaenoic acid by the heterotrophic marine dinoflagellate Crypthecodinium cohnii. Process Biochemistry, 34, 633-637. 44. Chen, H. & Chen, F. * (1999). Effects of methyl jasmonate and salicylic acid on cell growth and cryptotanshinone formation in Ti transformed Salvia miltiorrhiza cell suspension cultures. Biotechnology Letters, 21(9), 803-807. 43. Zhang, Y.M. & Chen, F. * (1999). A simple method for efficient separation and purification of c-phycocyanin and allophycocyanin from Spirulina platensis. Biotechnology Techniques (changed to Biotechnology Letters), 13(9), 601-603. 42. Chen, H. & Chen, F. * (1999). Kinetics of cell growth and secondary metabolism of a high-tanshinone-producing line of the Ti transformed Salvia miltiorrhiza cells in suspension cultures. Biotechnology Letters, 21(8), 701-705. 41. Zhang, X.W., Gong, X.D. & Chen, F.* (1999). Kinetic models for astaxanthin production by high cell density mixotrophic culture of the microalga Haematococcus pluvialis. Journal of Industrial Microbiology Biotechnology, 23, 691-696. 40. Boussiba, S., Wang, B., Yuan, J.P., Zarka. A. & Chen, F.* (1999). Changes in pigment profile in the green alga Haematococcus pluvialis exposed to environmental stresses. Biotechnology Letters, 21, 601-604. 39. Zhang, X.W., Zhang, Y.M. & Chen, F.* (1999). Application of mathematical models to the determination optimal glucose concentration and light intensity for mixotrophic culture of Spirulina platensis. Process Biochemistry, 34(5), 477-481. 38. Shi, X.M., Liu, H.J., Zhang, X.W. & Chen, F.* (1999). Production of biomass and lutein by Chlorella protothecoides at various glucose concentrations in heterotrophic cultures. Process Biochemistry, 34(4), 341-347. 37. Ren, G. & Chen, F. * (1999). Simultaneous quantification of ginsenosides in American ginseng (Panax quinquefolium) root powder by visible/near infrared reflectance spectroscopy. Journal of Agricultual & Food Chemistry, 47, 2771-2775. 36. Chen, H., Chen, F. *, Zhang, Y.L. & Song, J.Y. (1999). Production of lithospermic acid B and rosmarinic acid in hairy root cultures of Salvia miltiorrhiza. Journal of Industrial Microbiology & Biotechnology, 22, 133-138. 35. Ren, G. & Chen, F. * (1999). Degradation of ginsenosides in American ginseng (Panax quiquefolium) extracts during microwave and conventional heating. Journal of Agricultural & Food Chemistry, 47(4), 1501-1505. 34. Shi, X.M. & Chen, F. * (1999). Production and rapid extraction of lutein and the other lipid-soluable pigments from Chlorella protothecoides grown under heterotrophic and mixotrophic conditions. Nahrung/Food (changed to Molecular Nutrition and Food Research), 43(2), 109-113. 33. Yuan, J.P. & Chen, F. * (1999). Simultaneous separation and determination of sugars, ascorbic acid and furanic compounds by HPLC-dual detection. Food Chemistry, 64(3), 423-427. 32. Yuan, J.P. & Chen, F. * (1999). Hydrolysis kinetics of astaxanthin esters and stability of astaxanthin of Haematococcus pluvialis during saponification. Journal of Agricultural & Food Chemistry, 47(1), 31-35. 31. Zhang, X.W., Zhang, Y.M. & Chen, F.* (1998). Kinetic models for phycocyanin production by high cell density mixotrophic culture of the microalga Spirulina platensis. Journal of Industrial Microbiology & Biotechnology, 21(6), 283-388. 30. Yuan, J.P. & Chen, F. * (1998). Degradation of ascorbic acid in aqueous solution. Journal of Agricultural & Food Chemistry, 46(12), 5078-5082. 29. Vazhappilly, R. & Chen, F. * (1998). Heterotrophic production potential of omega-3 polyunsaturated fatty acids by microalgae and algae-like microorganisms. Botanica Marina, 41, 553-558. 28. Yuan, J.P. & Chen, F. * (1998). Chromatographic separation and purification of trans-astaxanthin from the extracts of Haematococcus pluvialis. Journal of Agricultural & Food Chemistry, 46(8), 3371-3375. 27. Li, X., Lin, W., Gao, P. & Chen, F. (1998). Endoglucanase S, a novel endocellulase exhibiting exoglucanase activity from a newly isolated Streptomyces sp. LX. Journal of Applied Microbiology, 85, 347-356. 26. Yuan, J.P., Chen, H. & Chen, F. * (1998). Simultaneous determination of rosmarinic acid, lithospermic acid B and related phenolics in Salvia miltiorrhiza by HPLC. Journal of Agricultural & Food Chemistry, 46(7), 2651-2654. 25. Li, X. & Chen, F. * (1998). Improvement in isolation of gliding bacteria by the elimination of soluable sugars. Biotechnology Techniques (changed to Biotechnology Letters), 12(5), 343-345. 24. Ren, G. & Chen, F. * (1998). Drying of American ginseng (Panax quinquefolium) roots by microwave-hot air combination. Journal of Food Engineering, 35(4), 433-443. 23. Gong, X. & Chen, F. * (1998). Influence of medium components on astaxanthin content and production of Haematococcus pluvialis. Process Biochemistry, 33(4), 385-391. 22. Yuan, J.P. & Chen, F. * (1998). Separation and identification of furanic compounds in fruit juices and drinks by HPLC-PDA detection. Journal of Agricultural & Food Chemistry, 46, 1286-1291. 21. Vazhappilly, R. & Chen, F. * (1998). Eicosapentaenoic acid and docosahexaenoic acid production potential of microalgae and their heterotrophic growth. Journal of the American Oil Chemists Society, 75, 393-397. 20. Chen, H., Yuan, J.P., Chen, F. *, Zhang, Y.L. & Song, J.Y. (1997). Tanshinone production in Ti transformed Salvia miltiorrhiza cell suspension cultures. Journal of Biotechnology, 58(3), 147-156. 19. Chen, F. *, Chen, H. & Gong, X. (1997). Mixotrophic and heterotrophic growth of Haematococcus lacustris and rheological behaviour of the cell suspensions. Bioresource Technology, 62(1-2), 19-24. 18. Gong, X.D. & Chen, F. * (1997). Optimization of culture medium for growth of Haematococcus pluvialis. Journal of Applied Phycology, 9(5), 437-444. 17. Shi, X.M., Chen, F. *, Yuan, J.P. & Chen, H. (1997). Heterotrophic production of lutein by selected Chlorella strains. Journal of Applied Phycology, 9(5), 445-450. 16. Ren, G., Chen, F. *, Lian, H., Zhao, J. and Gao, X. (1997). Changes in hormone contents of Panax quinquefolium seeds during stratification. Journal of Horticultural Science (changed to Journal of Horticultural Science & Biotechnology) , 72(6), 901-906. 15. Gong, X.D. & Chen, F. * (1997). Rapid detection of heterotrophic growth of Haematococcus pluvialis using indirect conductimetry. Biotechnology Techniques (changed to Biotechnology Letters), 11(11), 841-844. 14. Ren, G. and Chen, F. * (1997). Determination of moisture content of ginseng by near infra-red reflectance spectroscopy. Food Chemistry, 60, 433-436. 13. Yuan, J.P. & Chen, F. * (1997). Identification of astaxanthin isomers in Haematococcus lacustris by HPLC-photodiode array detection. Biotechnology Techniques (changed to Biotechnology Letters), 11(7), 455-459. 12. Yuan, J.P., Gong, X.D. & Chen, F. * (1997). Separation and analysis of carotenoids and chlorophylls in Haematococcus lacustris by high-performance liquid chromatography photodiode array detection. Journal of Agricultural & Food Chemistry, 45(5), 1952-1956. 11. Chen, F. * & Zhang, Y. (1997). High cell density mixotrophic culture of Spirulina platensis on glucose for phycocyanin production using a fed-batch system. Enzyme and Microbial Technology, 20, 221-224. ( 10. Shi, X.M. and Chen, F. * (1997). Stability of lutein under various storage conditions. Nahrung/Food (changed to Molecular Nutrition and Food Research), 41(1), 38-41. 9. Chen, F.* (1996). High cell density culture of microalgae in heterotrophic growth. Trends in Biotechnology, 14(11), 421-426 [featured in the cover of the journal; the article was also cited by a landmark article in Science (292: 2073-2075, 2001) as one of the major reasons they initiated the study]. 8. Chen, F. *, Zhang, Y. & Guo, S. (1996). Growth and phycocyanin formation of Spirulina platensis in photoheterotrophic culture. Biotechnology Letters, 18(5), 603-608. 7. Chen, F. * & Johns, M.R. (1996). Heterotrophic growth of Chlamydomonas reinhardtii on acetate in chemostat culture. Process Biochemistry, 31(6), 601-604. 6. Chen, F. & Johns, M.R. (1996). High cell density culture of Chlamydomonas reinhardtii on acetate using fed-batch and hollow-fibre cell-recycle systems. Bioresource Technology, 55(2), 103-110. 5. Chen, F. * & Johns, M.R. (1996). Relationship between substrate inhibition and maintenance energy of Chlamydomonas reinhardtii in heterotrophic culture. Journal of Applied Phycology, 8(1), 15-19. 4. Yuan, J.P., Gong X.-D. & Chen, F. * (1996). Separation and identification of astaxanthin esters and chlorophylls in Haematococcus lacustris by HPLC. Biotechnology Techniques (changed to Biotechnology Letters), 10(9), 655-660. 3. Chen, F. *& Johns, M.R. (1995). A strategy for high cell density culture of heterotrophic microalgae with inhibitory substrates. Journal of Applied Phycology, 7, 43-46. 2. Chen, F. * & Johns, M.R. (1994). Substrate inhibition of Chlamydomonas reinhardtii by acetate in heterotrophic culture. Process Biochemistry, 29, 245-252. 1. Chen, F.* & Johns, M.R. (1991). Effect of C/N ratio and aeration on the fatty acid composition of heterotrophic Chlorella sorokiniana. Journal of Applied Phycology, 3, 203-209.

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