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个人简介

教育经历 1993.09—1998.06 上海医科大学临床医学系学士 1998.09—2003.06 复旦大学上海医学院生物化学与分子生物学专业博士研究生 工作经历 2003.08—2006.07 美国纽约州立基础研究所,Research Scientist 2006.07—2013.01 美国纽约斯隆凯特琳癌症中心,Research Associate 2013.06—至今 复旦大学基础医学院研究员 2019.11—2020.11 上海市崇明区医疗保障局副局长 获得奖项 2018,复旦大学三八红旗手 2006,第十届国际Alzheimer’s Disease 及其相关疾病大会 Fellowship 2003,上海市科学技术进步奖二等奖(第三完成者) 2002,上海市医学科技奖二等奖(第四完成者)

研究领域

肿瘤发生与微环境 环境与健康

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Wang, B. #, Zhao, Y. #, Li, Y. #, Xu, Y. #, Chen, Y., Jiang, Q., Yao, D., Zhang, L., Hu, X. *, Fu, C. *, Zhang, S. *, and Chen, S. * (2022) A plasma SNORD33 signature predicts platinum benefit in metastatic triple-negative breast cancer patients. Mol Cancer 21, 22 Zhou, Y. #, Hu, L. #, Tang, W., Li, D., Ma, L., Liu, H., Zhang, S., Zhang, X., Dong, L., Shen, X., Chen, S. *, Xue, R. *, and Zhang, S. * (2021) Hepatic NOD2 promotes hepatocarcinogenesis via a RIP2-mediated proinflammatory response and a novel nuclear autophagy-mediated DNA damage mechanism. J Hematol Oncol 14, 9 Wang, X. X. #, Zhang, S. #, Dong, P. P. #, Li, Y. H., Zhang, L., Shi, S. H., Yu, Z. Q. *, and Chen, S. *. (2021) MRCKbeta links Dasm1 to actin rearrangements to promote dendrite development. J Biol Chem 296, 100730 Wang, S. #, Cai, J. #, Zhang, S., Dong, M., Zhang, L., Xu, Y., Shen, B. *, and Chen, S. * (2021) Loss of polarity protein Par3, via transcription factor Snail, promotes bladder cancer metastasis. Cancer Sci 112, 2625-2641 Dong, P. #, Wang, X. #, Liu, L. #, Tang, W., Ma, L., Zeng, W., Sun, S., Zhang, L., Zhang, N., Shen, X., Janssen, H. L. A., Dong, L. *, Zhang, S. *, and Chen, S. * (2020) Dampened VEPH1 activates mTORC1 signaling by weakening the TSC1/TSC2 association in hepatocellular carcinoma. J Hepatol 73, 1446-1459 Zhao, G. X. #, Xu, Y. Y. #, Weng, S. Q. #, Zhang, S., Chen, Y., Shen, X. Z. *, Dong, L. *, and Chen, S. * (2019) CAPS1 promotes colorectal cancer metastasis via Snail mediated epithelial mesenchymal transformation. Oncogene 38, 4574-4589 Liu, W. A., Chen, S., Li, Z., Lee, C. H., Mirzaa, G., Dobyns, W. B., Ross, M. E., Zhang, J., and Shi, S. H. (2018) PARD3 dysfunction in conjunction with dynamic HIPPO signaling drives cortical enlargement with massive heterotopia. Genes Dev 32, 763-780 Chen, S. #*, Chen, J. #, Shi, H., Wei, M., Castaneda-Castellanos, D. R., Bultje, R. S., Pei, X., Kriegstein, A. R., Zhang, M., and Shi, S. H. * (2013) Regulation of microtubule stability and organization by mammalian Par3 in specifying neuronal polarity. Dev Cell 24, 26-40 Brown, K. N., Chen, S., Han, Z., Lu, C. H., Tan, X., Zhang, X. J., Ding, L., Lopez-Cruz, A., Saur, D., Anderson, S. A., Huang, K., and Shi, S. H. * (2011) Clonal production and organization of inhibitory interneurons in the neocortex. Science 334, 480-486 Chen, S., Li, B., Grundke-Iqbal, I., and Iqbal, K. * (2008) I1PP2A affects tau phosphorylation via association with the catalytic subunit of protein phosphatase 2A. J Biol Chem 283, 10513-10521

学术兼职

2017.05-今上海细胞生物学会,理事

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