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分子药理学、免疫药理学和受体药理学

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Lobel, P., Fujimoto, K., Ye, R.D., Griffiths, G., and Kornfeld, S. (1989). Mutations in the cytoplasmic domain of the 275 kd mannose 6-phosphate receptor differentially alter lysosomal enzyme sorting and endocytosis. Cell 57:787-796. Silverman, G.A., Ye, R.D., Pollock, K.M., Sadler, J.E., and Korsmeyer, S.J. (1989). Use of yeast artificial chromosome clones for mapping and walking within human chromosome segment 18q21.3. Proc. Natl. Acad. Sci. U.S.A. 86:7485-7489. Kravchenko, V.V., Pan, Z., Han, J., Ulevitch, R.J., and Ye, R.D. (1995). Platelet-activating factor induces NF-kB activation through a G protein-coupled pathway. J. Biol. Chem., 270:14928-14934. Pan, Z., Zuraw, B.L., Lung, C.-C., Prossnitz, E.R., Browning, D.B., and Ye, R.D. (1996). Bradykinin stimulates NF-kB activation and interleukin-1beta gene expression in cultured human fibroblasts. J. Clin. Invest., 98:2042-2049. Hsu, M.H., Wang, M., Browning, D.D., Mukaida, N., and Ye, R.D. (1999) NF-kB activation is required for C5a-induced IL-8 gene expression in mononuclear cells. Blood 93:3241-3249. Xie, P., Browning, D.D., Hay, N., Mackman, N., and Ye, R.D. (2000) Activation of NF-kB by bradykinin through a Gq and Gbeta/gamma-dependent pathway that involves phosphoinositide 3-kinase and Akt. J. Biol. Chem., 275:24907-24914. Ye, R.D. (2001) Regulation of NF-kB activation by G-protein-coupled receptors (review). J. Leuk. Biol., 70:839-848. He, R., Sang, H., and Ye, R.D. (2003) Serum Amyloid A Induces IL-8 Secretion through a G protein-coupled Receptor, FPRL1/LXA4R. Blood, 101:1572-1581. Li, Z., Xi, X., Gu, M., Feil, R., Ye, R.D., Eigenthaler, M., Hofmann, F., and Du, X. (2003) A stimulatory role for cGMP-dependent protein kinase in platelet activation. Cell, 112:77-86. Marty, C., Browning, D.D. and Ye, R.D. (2003) Identification of tetratricopeptide repeat 1 as an adaptor protein that interacts with heterotrimeric G-proteins and the small GTPase Ras. Mol. Cell. Biol., 23:3847-3858. Cheng, N., He, R.L., Tian, J., Ye, P.P. and Ye, R.D. (2008) Cutting Edge: TLR2 is a functional receptor for acute-phase serum amyloid A. J. Immunol. 181:22-26. He, R.L., Zhou, J., Hanson, C., Chen, J., Cheng, N., and Ye, R.D. (2009) Serum amyloid A induces G-CSF expression and neutrophilia via Toll-like receptor 2. Blood. 113:429-437. Ye, R.D., Boulay, F., Wang, J.M., Dahlgren, C., Gerard, C., Parmentier, M., Serhan, C.N., and Murphy, P.M. (2009) International Union of Pharmacology: Nomenclature for the formyl peptide receptor (FPR) family. Pharmacol. Rev. 61:119-161. Feng Q, Deng J, Cheng N, Welch EJ, Zhang Y, Malik AB, Flavell RA, Dong C, Ye RD. (2009) A non-redundant role for MKP5 in limiting ROS production and preventing LPS-induced vascular injury. EMBO J. 28:2896-2907. Chen J, Tang H, Hay N, Xu J, Ye RD (2010) Akt isoforms differentially regulate neutrophil functions. Blood 115:4237-4246. Marty, C. and Ye, R.D. (2010) Heterotrimeric G protein signaling outside the realm of 7TM receptors (mini-revie w). Mol. Pharmacol. 78:12-18. Ye RD. (2010) Biased agonism in chemoattractant signaling (editorial). J. Leuk. Biol. 87:959-961.

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