曾伟 - 华南理工大学 - 化学与化工学院

个人简介

2000年毕业后考入四川大学化学学院攻读有机化学专业博士学位（导师为秦圣英教授）， 2004年1月- 2005年1月在香港大学Prof. V. W. W. Yam小组做R. A (Research Assistant) 研究工作，主要工作涉及氮杂和硫杂大环化合物及其过渡金属络合物的设计合成和发光性能研究；2005年3月至2006年11月在美国North Carolina State University，Prof. Christian Melander 小组做博士后研究工作，主要工作涉及具有生物抗癌活性的天然产物分子的设计、化学和酶合成及其对DNA的切割和蛋白质的键合性能研究；2006年11月至2008年10月在美国The State University of New York at Buffalo，Prof. Sherry Chemler 小组继续做博士后研究工作，主要工作涉及杂环化合物的不对称合成和天然产物的全合成。2008年11月，被聘为华南理工大学“百人计划”杰出青年教师，在华南理工大学化学与化工学院任教授，2010年1月入选教育部“新世纪优秀人才支持计划”。 2008年底回国后主要工作涉及利用过渡金属催化的相关反应来构建含氮化合物及氮杂环化合物，发展新型有机反应类型，研究反应机理；进一步将所发展的有机合成方法学应用于生物活性分子、材料分子、药物分子及精细化学品等的制备。Zeng Group先后承担或参与了广州市科技计划项目、教育部博士点基金、中科院“西部之光”联合学者、教育部新世纪人才支持计划、国家自然科学基金和国家重点研发计划等省部和国家级项目多项。到目前为止，曾伟教授先后以第一作者或者通讯联系人在化学类国际主流期刊Nat. Commun.; J. Am. Chem. Soc.; Angew. Chem., Int. Ed.; Chem. Sci.; ACS Catal.; Chem. Commun.; Org. Lett.; J. Org. Chem.; Adv. Synth & Catal.等上共发表了近60篇高水平学术论文。

研究领域

1、过渡金属催化高选择性C-X (X = H, C, N, Si, etc) Bond官能化反应 2、不对称催化与合成 3、非天然氨基酸化学合成 4、医药中间体、聚氨酯添加剂、涂料和香料等精细化学品的研发

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Yang, C.; Zhou, X. Y.; Shen, L. X.; Ke, Z. F*.; Jiang, H. F.; Zeng, W*. “Mn(I)-Catalyzed U-Turn-Like Rearrangement of beta, gamma-Unsaturated Alcohols". Nat. Commun. 2023, 14, 1862. Xie, H. S.; Luo, Z. F.; Chen, F. J*.; Jiang, H. F.; Zeng, W*. “Photocatalyzed alkoxycarbonylmethylation of pyridines with aalpha-diazoaxetates". Org. Chem. Front. 2023, 10, 1270-1274. Xiong, L.; Chen, F. J*.; Wu, Y. H.; Hu, X. W.; Ruan, Z. X.; Jiang, H. F.; Zeng, W*. “Cyclocarboamination of Alkynes with N‑Aminopyridiniums by Photoredox Catalysis”. Org. Lett. 2022, 24, 7865-7860. Chen, F. J.; Huang, X.; Yang, C.; Jiang, H. F.; Zeng, W*. “Photocatalyzed Coupling-Cyclization of ortho-Alkynylaryl Vinylethers with Arylsulfonyl Azides”. J. Org. Chem. 2021, 86, 14572. Huang, X.; Chen, X.; Xie, H. S*.; Tan, Z.; Jiang, H. F.; Zeng, W*. “Visible-Light-Catalyzed in Situ Dentrogenative Sulfonylation of Sulfonylhydrazones”. Org. Lett. 2021, 23, 6784. Chen, X.; Li, M. K.; Liu, Z. P.; Yang, C.; Xie, H. S*.; Hu, X. W.; Su, S. J*.; Jiang, H. F.; Zeng, W*. “Bimetal Cooperatively Catalyzed Arylalkynylation of Alkynylsilanes”. Org. Lett. 2021, 23, 6724. Hu, X. W.; Tan, Z.; Xiong, L.; Yang, C.; Jiang, H. F.; Zeng, W*. “Rh(III)-Catalyzed Csp2-Csp3 σ-Bond Enolation of α-Indolyl Alcohols”. Org. Lett. 2021, 23, 3965. Yang, C.; Liu, Z. P.; Hu, X. W.; Xie, H. S.; Jiang, H. F.; Zeng, W*. “Rh(III)-Catalyzed Csp2-Csp3 Bond Alkoxylation of a-Indolyl Alcohols via C-C sigma Bond Cleavage”. Org. Chem. Front. 2021, 8, 2949. Chen, F. J.; Shao, Y. X.; Li, M.K.; Yang, C.; Su, S. J*.; Jiang, H. F.; Ke, Z. F*.; Zeng, W*. “Photocatalyzed Cycloaromatization of Vinylsilanes with Arylsulfonyl Azides”. Nat. Commun. 2021, 12, 3304. Liu, Z, P.; Hu, X. W.; Yang,C.; Xie, H. S.; Jiang,H. F.; Jiang,F. B.; Zeng, W*.“Rh(III)-Catalyzed Csp2-Csp3 Bond Cleavage/Carbonylethylation of alpha-Indolyl Alcohols”. Adv. Synth. Catal. 2021, 363, 1672. Hu, X. W.; Tan, Z.; Liu, Z. P.; Liu, Z. P.; Chen, F. J.; Jiang, H. F.; Zeng, W*. "Rh(III)-catalyzed sulfonylamination of alpha-indolyl alcohols via Csp2-Csp3 bond cleavage". Org. Chem. Front. 2021, 8, 983. Hu, X. W.; Shao, Y. X.; Xie, H. S*.; Chen, X.; Chen, F. J.; Ke, Z. F*.; Jiang, H. F.; Zeng, W*. “Direct Carbon-Carbon sigma Bond Amination of Unstrained Arylalkylketones”. ACS Catal. 2020, 10, 8402. Chen,F, J.; Yang,C.; Hu,X. W.; Zhang,X. Q.; Xie, H. S.; Jiang,H. F.; Jiang,F. B.; Zeng, W*.“Photocatalyzed Formal Carbooxygenation of Terminal Alkynes”. Org. Chem. Front. 2020, 7, 1600. Gui, J.; Xie, H. S.; Chen, F. J.; Liu, Z. P.; Zhang, X. Q.; Jiang, F. B.; Zeng, W*. Bronsted Acid/Visible-Light-Promoted Markovnikov Hydroamination of Vinylarenes with Arylamines". Org. Biomol. Chem. 2020, 18, 956. Huang, J. M.; Hu, X. W.; Chen, F. J.; Gui, J.; Zeng, W*. "Rhodium(I)-Catalyzed Vinylation/[2+1] Carbocyclization of 1,6-Enynes with a-Diazocarbonyl Compounds". Org. Biomol. Chem. 2019, 17, 7042. Xie, H.; Shao, Y.; Gui, J.; Lan, J.; Liu, Z.; Ke, Z*.; Deng, Y.; Jiang, H.; Zeng, W.* Co(II)-Catalyzed Regioselective Pyridine C–H Coupling with Diazoacetates". Org. Lett. 2019, 21, 3427. Gui, J.; Xie, H.; Jiang, H.; Zeng, W*."Visible-Light-Mediated Sulfonylimination of Tertiary Amines with Sulfonylazides Involving Csp3–Csp3 Bond Cleavage". Org. Lett. 2019, 21, 2804. Yang, H, H.; An, B. B.; Li, X. S*.; Zeng, W*. “Evaluation of 4-Phenylamino-Substituted Naphthalene-1,2-Diones as Tubulin Polymerization Inhibitors”. Bioorg. Med. Chem.Lett. 2018, 28, 3057. Hu, X. W.; Chen, F. J.; Deng, Y. F.; Jiang, H. F.; Zeng, W*. "Zn(OAc)2-Catalyzed C3-Carbonylacetylation of Indoles with α-Diazoketones Involving Wolff Rearrangement". Org. Lett. 2018, 20, 6140. Xie, H. S.; Lan, J. Y.; Gui, J.; Chen, F. J.; Jiang, H. F.; Zeng, W*. " Ru(II)-Catalyzed Coupling-Cyclization of Sulfoximines with alpha-Carbonyl Sulfoxonium Ylides as an Approach to 1,2-Benzothiazines". Adv. Synth. Catal. 2018, 360, 3534. Chen, Z. Y.; Hu, X. W.; Huang, J. M.; Zeng, W*. "Rhodium (I)-Catalyzed Coupling-Cyclization of C=O Bonds with alpha-Diazoketones". Org. Lett. 2018, 20, 3980. Hu, X. W.; Chen, X.; Shao, Y.; Xie, H. S.; Deng, Y. F.; Ke, Z. F*.; Jiang, H. F.; Zeng, W*. “Co(III)-Catalyzed Coupling-Cyclization of Aryl C-H Bonds with a-Diazoketones Involving Wolff Rearrangement”. ACS Catal.2018, 8, 1308. Xie, H. S.; Ye, Z. R.; Ke, Z. F.;*Lan. J. Y.; Jiang, H. F.; *Zeng, W*.“Rh(III)-Catalyzed Regioselective Intermolecular N-Methylene Csp3-H Bond Carbenoid Insertion”. Chem. Sci. 2018, 9, 985. Lan, JY.; Xie, HS.; Lu, XX.; Deng, YF.; Jiang, HF.; Zeng, W*. “Co(II)-Catalyzed Regioselective Cross-Dehydrogenative Coupling of Aryl C-H Bonds with Carboxylic Acids”. Org. Lett. 2017, 19, 4279. Hu, X. W.; Chen, X.; Zhu, Y.; Deng, Y. F.; Zeng, H. Q.; Jiang, H. F.; Zeng, W*.“Rh(III)-Catalyzed Carboamination of Propargyl Cycloalkanols with Arylamines via Csp2-H/Csp3-Csp3 Activation”, Org. Lett. 2017. 19, 3474. Zhang, Z. H.; Liu, K. K.; Xun Chen, X.; Su, S. J.;* Deng, Y. F.; Zeng, W*. “Rhodium(III)-Catalyzed Indole-Directed Carbenoid Aryl C-H Insertion/Cyclization: Access to 1, 2-Benzocarbazoles”, RSC. Adv. 2017, 7, 30554. Bai, S. Y.; Chen, X.; Hu, X. W.; Deng, Y. F.; Jiang, H. F.; Zeng, W*. “Ir(III)-Catalyzed Aryl C-H Bond Carbenoid Functionalization Cascade: Access to 1,3-Dihydroindole-2-Ones”, Org. Biomol. Chem. 2017, 15, 3638. Huang, F. S.; Chen, X.; Xie, Y.; Zeng, W*. “Progress in the Transition Metal-Catalyzed C(sp2)-H Bond Functionalization of Azoarenes”, Chin. J. Org. Chem. 2017, 37, 31. Chen, X.; Hu, X. W.; Deng, Y.; Jiang, H. F.; Zeng, W*. “A [4 + 1] Cyclative Capture Access to Indolizines via Cobalt(III)-Catalyzed Csp2-H Bond Functionalization”, Org. Lett. 2016. 18, 4742. Xiao, X. S.; Hou, C.; Zhang, Z. H.; Ke, Z. F*.; Lan, J. Y.; Jiang, H. F.; Zeng, W*. “Ir(III)-Catalyzed Regioselective Intermolecular Unactivated Secondary Csp3-H Bond Amidation”, Angew. Chem., Int. Ed. 2016, 55, 11897. Xiao, X. S.; Zhang, W.; Lu, X. X.; Deng, Y. F.; Jiang, H. F.; Zeng, W*. “Copper-Catalyzed Addition of Alkylboranes to Iminoacetates: Access to alpha-Alkyl Branched alpha-Amino Acids”, Adv. Synth. Catal.2016, 358, 2497. Chen, TF.; Chen, X.; Wei, J.; Lin D.; Xie. Y.; Zeng, W*. “Copper-Catalyzed Cascade Cycloamination of α-Csp3–H Bond of N-Aryl Ketimines with Azides: Access to Quinoxalines”, Org. Lett. 2016, 18, 2078. Xie, Y.; Chen, X.; Liu, X.; Su, S. –J.; Li, J.; Zeng, W*. “Rh(III)-Catalyzed Relay Carbenoid Functionalization of Aromatic C-H Bonds: Access to π-Conjugated Fused Heteroarenes”, Chem. Commun. 2016,52, 5856. Wei,J.; Jiang,J.; Xiao, X.; Lin, D *.; Deng, Y.; Ke, Z *.; Jiang, H.; Zeng, W*. “Copper-Catalyzed Regioselective C-H Sulfonylation of 8-Aminoquinolines”, J. Org. Chem. 2016, 81, 946. Chen, X.; Hu, X. W.; Bai, S. Y.; Deng, Y.; Jiang, H. F.; Zeng, W*. “Rh(III)-Catalyzed [4 + 2] Annulation of Indoles with Diazo Compounds: Access to Pyrimido[1,6-a]indole-1(2H)-ones”, Org. Lett. 2016, 18,192. Chen, X.; Xie, Y.; Xiao, X.; Li, G.; Deng, Y.; Jiang, H.; Zeng, W*. “Rh(III)-Catalyzed Chelation-Assisted Intermolecular Carbenoid Functionaliztion of a-Imino Csp3-H Bonds”, Chem. Commun. 2015, 51, 15328. Xiao, X.; Xie, Y.; Bai, S.; Deng, Y.; Jiang, H.; Zeng, W*. “Transition-Metal-Free Tandem Chlorocyclization of Amines with Carboxylic Acids: Access to Chloroimidazo[1,2-a]pyridines”, Org. Lett. 2015, 17, 3998. Xie, Y,; Chen, T. F.; Fu, S. M.; Jiang, H. F.; Zeng, W*. “Pd-Catalyzed Carbonylative Cycloamidation of Ketoimines for Synthesis of Pyrido [1, 2-a] Pyrimidin-4-Ones”, Chem. Commun. 2015, 51, 9377. Zhang, W.; Wei, J.; Fu, S. M.; Lin, D.; * Jiang, H.;Zeng, W*. “Highly Steroselective Ruthenium(II)-Catalyzed Direct C2-Syn-Alkenylation of Indoles with Alkynes”, Org. Lett. 2015, 17, 1349. Liu, J. Z.; Xie, Y.; Zeng, W*.; Lin, D.; Deng, Y.; Lu, X*. “Pd(II)-Catalyzed Pyridine N-Oxide-Directed Arylation of Unactivated Csp3-H bonds ”. J. Org. Chem. 2015, 80, 4618. Fu, S. M.; Yang, H. H.; Li, G. Q.; Deng, Y. F.; Jiang, H. F.; Zeng, W*. “Copper(II)-Catalyzed Enantioselective Intramolecular Cyclization of N-Alkenyl Ureas”. Org. Lett. 2015, 17, 1018. Li, M. Y.; Xie, Y.; Ye, Y*.; Zou, Y.; Jiang, H. F.; Zeng, W*. “Cu(I)-Catalyzed Transannulation of N-Heteroaryl Aldehydes or Ketones with Alkylamines via C(sp3)-H Amination”, Org. Lett.,2014, 16, 6232. Liang, L. B.; Fu, S. M.; Lin, D.; Zhang, X. Q.; Deng, Y. F.; Jiang, H. F.; Zeng, W*. “Ruthenium(II)-Catalyzed Direct Addition of Indole/Pyrrole C2-H Bonds to Alkynes”.J. Org. Chem. 2014, 79, 9472. Fu, M. Q.; Lin, D. E.; Deng, Y. F.; Zhang, X. Q.; Liu, Y. C.; Lai, C. S.; Zeng, W*. “Pd-Catalyzed Tandem Homocupling-Adol-Dehydration of ortho-Acylphenyl Iodides”, RSC Adv. 2014, 4, 23595. Qian, C.; Lin, D. E.; Deng, Y. F.; Zhang, X. Q.; Jiang, . HF.; Miao, G.; Tang, X. H.; Zeng, W*. “Palladium-catalyzed ortho-Functionalization of Azoarenes with Aryl Acylperoxides”, Org. Biomol. Chem. 2014, 12, 5866. Xie, Y.; Chen, T. F.; Fu, S. M.; Li, X. S.; Deng, Y. F.; Jiang, H. F.; Zeng, W*. “Pd-Catalyzed [3 + 2] Cycloaddition of Ketoimines with Alkynes via Directed sp3 C-H Bond Activations”, Chem. Commun. 2014, 50, 10699. Dang, L.; Liang, L. B.; Qian, C.; Fu, M. Q.; Ma, T. M*.;Xu, D. G*.; Jiang, H. F.; Zeng, W*. “Cu(OAc)2-Promoted Cascade Carboamination/Oxidative Cyclization of C-Acylimines with Alkenes”. J. Org. Chem.2014, 79, 769. Tang, H.; Qian, C.; Lin, D. E*.; Jiang, H. F.; Zeng, W*. “Palladium-Catalyzed Direct Oxidative C-H Cross-Coupling of Azoarenes with Alcohols”. Adv. Synth. Catal.2014, 356, 519. Xiong, F.; Qian, C.; Lin, D. E.; Zeng, W*.; Lu, X. X*. “Palladium-Catalyzed Cascade Oxidation/ sp2 C-H Acylation of Azoarenes with Aryl Methanes”. Org. Lett.2013, 15, 5444. Qian, C.; Chen, J. Y.; Fu, M. Q.; Zhu, S. Y.; Chen, W. H.; Jiang, H. F.; Zeng, W*. “An Unusual 1, 2-Aryl Shift in Palladium-Catalyzed Cross-Coupling Ethoxycarbonylation of Arylboronic Acids with a-Iminoesters”. Org. Biomol. Chem.,2013, 11, 6013. Zhu, S. J.; Lu, X. X.; Luo, YT.; Zhang, W.; Jiang, H. F.; Yan, M.; Zeng. W*. “Ruthenium(II)-Catalyzed Regioselective Reductive Coupling of α-Imino Esters with Dienes”. Org. Lett. 2013, 15, 1440. Luo, Y. T.; Lu, X. X.; Ye, Y*.; Guo, Y.; Jiang, H. F.; Zeng, W*. “Pd-Catalyzed Tandem Cyclization of Ethyl Glyoxalate and Amines: Rapid Assembly of Highly Substituted Cyclic Dehydro-α-Amino Acid Derivatives”. Org. Lett. 2012, 14, 5640. Chen, J. Y.; Lu, X. X.; Lou, W. Y.; Ye, Y.; Jiang, H. F.; Zeng, W*. “Pd(II)-Catalyzed Enantioselective Arylation of a-Imino Esters”. J. Org. Chem. 2012, 77, 8541. Fu, S. M.; Jiang, H. F.; Deng, Y. F.; Zeng, W*. “Palladium-Catalyzed Intramolecular Sulfonamidation/Oxidation ofImine: Access to Multifunctional Benzimidazoles”. Adv. Synth. Catal. 2011, 353, 2795. Zhu, S. J.; Dong, J.; Fu, S. M.; Jiang, H. F.; Zeng, W*. “Cu(II)-Catalyzed Intermolecular Amidation of C-Acylimine: A Convenient Access to gem-Diamino Acid Derivatives”. Org. Lett. 2011, 13, 4914.