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个人简介

1982年 兰州大学化学系获学士学位 1985年 兰州大学化学系获硕士学位 1996年 日本千叶大学获博士学位 1985-1991年 华中师范大学化学系 教师 1991-1993年 日本茨城大学研修(日本文部省国费奖学金) 1996-1998年 武汉大学博士后 2000年 武汉大学化学系 教授 2000年6-9月 厦门大学化学系教育部高级访问学者 2002年8-11月美国Iowa州立大学和加州大学Riverside分校高级访问学者 2005年 获教育部新世纪优秀人才支持计划资助 2006年 获国家杰出青年科学基金资助 2009年 聘为武汉大学“珞珈”教授

研究领域

(1)基于衍生化技术的复杂样品质谱分析新方法 (2)代谢组分析方法 (3)微型化样品前处理技术与色谱-质谱联用 (4)新型分离介质(整体柱、纳米材料、磁性材料等)

近期论文

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Xue-Jiao You, Shan Zhang, Juan-Juan Chen, Feng Tang, Jingang He, Jie Wang, Chu-Bo Qi, Yu-Qi Feng, Bi-Feng Yuan, Formation and removal of 1,N6-dimethyladenosine in mammalian transfer RNA, Nucleic Acids Research, Volume 50, Issue 17, 23 September 2022, Pages 9858–9872, [DOI:10.1093/nar/gkac770] Jiang-Hui Ding, Meng-Yuan Chen, Neng-Bin Xie, Conghua Xie, Nanxiang Xiong, Jin-Gang He, Jie Wang, Cheng Guo, Yu-Qi Feng, Bi-Feng Yuan, Quantitative and site-specific detection of inosine modification in RNA by acrylonitrile labeling-mediated elongation stalling, Biosensors and Bioelectronics, Volume 219, 2023, [DOI:10.1016/j.bios.2022.114821] Ya-Li Bai, Xiaoming Yin, Cai-Feng Xiong, Bao-Dong Cai, Yan Wu, Xiao-Yun Zhang, Zhenwei Wei, Tiantian Ye, Yu-Qi Feng,Neophaseic acid catabolism in the 9′-hydroxylation pathway of abscisic acid in Arabidopsis thaliana, Plant Communications, Volume 3, Issue 5,2022, [DOI:10.1016/j.xplc.2022.100340] Chen, YS., Feng, YQ. Rapid Determination of Endogenous 20-Hydroxyecdysone in Plants on MALDI-TOF/TOF Mass Spectrometry via Chemical Labeling Based on Boronate Affinity. J. Anal. Test. 6, 318–326 (2022). [DOI:10.1007/s41664-021-00179-8 Xiao, H. M.; Yang, X.; Zheng, F.; Tshepelevitsh, S.; Wang, X.; Yao, X. J.; Leito, I.; Feng, Y. Q., Quantitative analysis of the relationship of derivatization reagents and detection sensitivity of electrospray ionization-triple quadrupole tandem mass spectrometry: Hydrazines as prototypes. Anal Chim Acta 2021, 1158, 338402.[DOI: 10.1016/j.aca.2021.338402] Cai, W. J.; Zeng, C.; Zhang, X. Y.; Ye, T.; Feng, Y. Q., A structure-guided screening strategy for the discovery and identification of potential gibberellins from plant samples using liquid chromatography-mass spectrometry assisted by chemical isotope labeling. Anal Chim Acta 2021, 1163, 338505.[DOI:10.1016/j.aca.2021.338505] Hu, Y.-N.; Zhan, J.-T.; Zhu, Q.-F.; Hu, T.; An, N.; Zhou, Z.; Liang, Y.; Wang, W.; Han, Z.; Wang, J.; Xu, F.-Q.; Feng, Y.-Q., A mathematical method for calibrating the signal drift in liquid chromatography - mass spectrometry analysis. Talanta 2021, 233.[DOI:10.1016/j.talanta.2021.122511] Wang, Q.; Ding, J.-H.; Xiong, J.; Feng, Y.; Yuan, B.-F.; Feng, Y.-Q., Site-specific quantification of 5-carboxylcytosine in DNA by chemical conversion coupled with ligation-based PCR. Chinese Chemical Letters 2021.[DOI: 10.1016/j.cclet.2021.05.020 ] Dai, Y.; Qi, C. B.; Feng, Y.; Cheng, Q. Y.; Liu, F. L.; Cheng, M. Y.; Yuan, B. F.; Feng, Y. Q., Sensitive and Simultaneous Determination of Uridine Thiolation and Hydroxylation Modifications in Eukaryotic RNA by Derivatization Coupled with Mass Spectrometry Analysis. Anal Chem 2021, 93 (18), 6938-6946.[DOI: 10.1021/acs.analchem.0c04630] Xiong, C. F.; Ding, J.; Zhu, Q. F.; Bai, Y. L.; Yin, X. M.; Ye, T. T.; Yu, Q. W.; Feng, Y. Q., Boron Isotope Tag-Assisted Ultrahigh-Performance Liquid Chromatography Coupled with High-Resolution Mass Spectrometry for Discovery and Annotation of cis-Diol-Containing Metabolites. Anal Chem 2021, 93 (5), 3002-3009.[DOI:10.1021/acs.analchem.0c05037] Liu, F. L.; Ye, T. T.; Ding, J. H.; Yin, X. M.; Yang, X. K.; Huang, W. H.; Yuan, B. F.; Feng, Y. Q., Chemical Tagging Assisted Mass Spectrometry Analysis Enables Sensitive Determination of Phosphorylated Compounds in a Single Cell. Anal Chem 2021, 93 (17), 6848-6856.[DOI:10.1021/acs.analchem.1c00915 ] Chen, Y.-S.; Feng, Y.-Q., Rapid Determination of Endogenous 20-Hydroxyecdysone in Plants on MALDI-TOF/TOF Mass Spectrometry via Chemical Labeling Based on Boronate Affinity. Journal of Analysis and Testing2021.[DOI: 10.1007/s41664-021-00179-8] Dai, Y.; Yuan, B.-F.; Feng, Y.-Q., Quantification and Mapping of DNA Modifications. RSC Chemical Biology2021.[DOI:10.1039/D1CB00022E] Cheng, M.-Y.; You, X.-J.; Ding, J.-H.; Dai, Y.; Chen, M.-Y.; Yuan, B.-F.; Feng, Y.-Q., Novel dual methylation of cytidines in the RNA of mammals. Chemical Science 2021.[DOI:10.1039/d1sc01972d ] Zhao, Q.; Zhou, Y.-L.; Yue, S.-W.; Lou, Y.-J.; Feng, Y.-Q., Combination of Modified QuEChERS and Disposable Polyethylene Pipet Assisted DLLME Based on Low Density Solvent Extraction for Rapid and Sensitive Determination of Fipronil and Its Metabolites in Eggs by GC-MS. Food Analytical Methods2021, 14 (5), 1021-1032.[DOI:10.1007/s12161-020-01948-4] Xu, J.; Yuan, Y.; Chen, Y. Y.; Xiong, C. F.; Zhang, Z.; Feng, Y. Q., Carboxylic submetabolome-driven signature characterization of COVID-19 asymptomatic infection. Talanta2021, 239, 123086.[DOI:10.1016/j.talanta.2021.123086 ] Chen, M.-Y.; Gui, Z.; Chen, K.-K.; Ding, J.-H.; He, J.-G.; Xiong, J.; Li, J.-L.; Wang, J.; Yuan, B.-F.; Feng, Y.-Q., Adolescent alcohol exposure alters DNA and RNA modifications in peripheral blood by liquid chromatography-tandem mass spectrometry analysis. Chinese Chemical Letters 2021.[DOI:10.1016/j.cclet.2021.08.094] Chen, M.-Y.; Qi, C.-B.; Tang, X.-M.; Ding, J.-H.; Yuan, B.-F.; Feng, Y.-Q., Comprehensive profiling and evaluation of the alteration of RNA modifications in thyroid carcinoma by liquid chromatography-tandem mass spectrometry. Chinese Chemical Letters2021.[DOI: 10.1016/j.cclet.2021.12.008] Wang, R. Q.; Ding, J.; Geng, Y.; Li, Y. Z.; Mei, Y. W.; Bao, K.; Yu, H. D.; Feng, Y. Q., CRB-SWATH: A Method for Enhancing Untargeted Precursor Ion Extraction and Automatically Constructing Their Tandem Mass Spectra from SWATH Datasets by Chromatographic Retention Behaviors. Anal Chem 2021, 93 (36), 12273-12280.[DOI:10.1021/acs.analchem.1c01841] Xiong, C. F.; Zhu, Q. F.; Chen, Y. Y.; He, D. X.; Feng, Y. Q., Screening and Identification of Epoxy/Dihydroxy-Oxylipins by Chemical Labeling-Assisted Ultrahigh-Performance Liquid Chromatography Coupled with High-Resolution Mass Spectrometry. Anal Chem2021, 93 (28), 9904-9911.[DOI:10.1021/acs.analchem.1c02058] An, N.; Zhu, Q. F.; Wang, Y. Z.; Xiong, C. F.; Hu, Y. N.; Feng, Y. Q., Integration of Chemical Derivatization and in-Source Fragmentation Mass Spectrometry for High-Coverage Profiling of Submetabolomes. Anal Chem 2021, 93 (32), 11321-11328.[DOI:10.1021/acs.analchem.1c02673] Feng, Y.; Chen, J. J.; Xie, N. B.; Ding, J. H.; You, X. J.; Tao, W. B.; Zhang, X.; Yi, C.; Zhou, X.; Yuan, B. F.; Feng, Y. Q., Direct decarboxylation of ten-eleven translocation-produced 5-carboxylcytosine in mammalian genomes forms a new mechanism for active DNA demethylation. Chem Sci 2021, 12 (34), 11322-11329.[DOI:10.1039/d1sc02161c] Ma, C. J.; Li, L.; Shao, W. X.; Ding, J. H.; Cai, X. L.; Lun, Z. R.; Yuan, B. F.; Feng, Y. Q., An enzyme-mediated bioorthogonal labeling method for genome-wide mapping of 5-hydroxymethyluracil. Chem Sci 2021, 12 (42), 14126-14132.[DOI:10.1039/d1sc03812e] Yin, X.; Bai, Y. L.; Ye, T.; Yu, M.; Wu, Y.; Feng, Y. Q., Cinnamoyl coA:NADP oxidoreductase like 1 regulates abscisic acid response by modulating phaseic acid homeostasis in Arabidopsis thaliana. Journal of experimental botany2021.[DOI:10.1093/jxb/erab474] Qin, Z. N.; Ding, J.; Yu, Q. W.; Zhou, P.; Feng, Y. Q., A boronic acid-modified C60 derivatization reagent for the rapid detection of 3-monochloropropane-1,2-diol using matrix-assisted laser desorption/ionization-mass spectrometry. Rapid Commun Mass Spectrom2021, 35 (19), e9169.[DOI:10.1002/rcm.9169] Feng, Y.; Ma, C.-J.; Ding, J.-H.; Qi, C.-B.; Xu, X.-J.; Yuan, B.-F.; Feng, Y.-Q., Chemical labeling – Assisted mass spectrometry analysis for sensitive detection of cytidine dual modifications in RNA of mammals. Analytica Chimica Acta 2020.[DOI:10.1016/j.aca.2019.11.016] Hu, Y. N.; Chen, D.; Zhang, T. Y.; Ding, J.; Feng, Y. Q., Use of ammonium sulfite as a post-column derivatization reagent for rapid detection and quantification of aldehydes by LC-MS. Talanta 2020, 206, 120172.[DOI:10.1016/j.talanta.2019.120172] Zheng, S. J.; Zheng, J.; Xiong, C. F.; Xiao, H. M.; Liu, S. J.; Feng, Y. Q., Hydrogen-Deuterium Scrambling Based on Chemical Isotope Labeling Coupled with LC-MS: Application to Amine Metabolite Identification in Untargeted Metabolomics. Anal Chem 2020, 92 (2), 2043-2051.[DOI:10.1021/acs.analchem.9b04512] Liu, F. L.; Qi, C. B.; Cheng, Q. Y.; Ding, J. H.; Yuan, B. F.; Feng, Y. Q., Diazo reagent labeling with mass spectrometry analysis for sensitive determination of ribonucleotides in living organisms. Anal Chem 2020. 92 (2), 2301-2309.[DOI:10.1021/acs.analchem.9b05122 ] An, N.; Cai, W.-J.; Zhu, Q.-F.; Wang, W.; Hussain, D.; Feng, Y.-Q., Metabolic profiling of organic acids in honey by stable isotope labeling assisted liquid chromatography-mass spectrometry. J Food Compos Anal 2020, 87.[DOI:10.1016/j.jfca.2020.103423] Cheng, Q.-Y.; Xiong, J.; Ma, C.-J.; Dai, Y.; Ding, J.-H.; Liu, F.-L.; Yuan, B.-F.; Feng, Y.-Q., Chemical tagging for sensitive determination of uridine modifications in RNA. Chem Sci 2020, 11 (7), 1878-1891.[DOI:10.1039/C9SC05094A] Ding, J. H.; Ma, C. J.; Chen, M. Y.; Chen, B.; Yuan, B. F.; Feng, Y. Q., Quantification and Single-Base Resolution Analysis of N1-Methyladenosine in mRNA by Ligation-Assisted Differentiation. Anal Chem 2020, 92 (3), 2612-2619.[DOI:10.1021/acs.analchem.9b04454] An, N.; Zhu, Q. F.; Yu, L.; Chen, Y. T.; Chen, S. L.; Feng, Y. Q., Derivatization assisted LC-p-MRM-MS with high CID voltage for rapid analysis of brassinosteroids. Talanta 2020, 217, 121058.[DOI:10.1016/j.talanta.2020.121058] Bai, Y.-L.; Hong, Z.-D.; Zhang, T.-Y.; Cai, B.-D.; Zhang, Y.-Z.; Feng, Y.-Q., A Method for Simultaneous Determination of 14 Carbonyl-Steroid Hormones in Human Serum by Ultra High Performance Liquid Chromatography–Tandem Mass Spectrometry. Journal of Analysis and Testing 2020, 4 (1), 1-12.[DOI:10.1007/s41664-020-00120-5] Ding, J.; Kind, T.; Zhu, Q. F.; Wang, Y.; Yan, J. W.; Fiehn, O.; Feng, Y. Q., In-Silico-Generated Library for Sensitive Detection of 2-Dimethylaminoethylamine Derivatized FAHFA Lipids Using High-Resolution Tandem Mass Spectrometry. Anal Chem2020, 92 (8), 5960-5968.[DOI:10.1021/acs.analchem.0c00172] Li, S.; Cai, W. J.; Wang, W.; Sun, M. X.; Feng, Y. Q., Rapid Analysis of Monosaccharides in Sub-milligram Plant Samples Using Liquid Chromatography-Mass Spectrometry Assisted by Post-column Derivatization. J Agric Food Chem 2020, 68 (8), 2588-2596.[DOI:10.1021/acs.jafc.9b07623] Zhu, Q. F.; Yan, J. W.; Ni, J.; Feng, Y. Q., FAHFA footprint in the visceral fat of mice across their lifespan. Biochim Biophys Acta Mol Cell Biol Lipids 2020, 1865 (5), 158639.[DOI:10.1016/j.bbalip.2020.158639] Qin, Z. N.; Ding, J.; Yu, Q. W.; Qi, C. B.; Wu, D. M.; Zhou, P.; Feng, Y. Q., Development of C60-based labeling reagents for the determination of low-molecular-weight compounds by matrix assisted laser desorption ionization mass spectrometry (II): Determination of thiols in human serum. Anal Chim Acta 2020, 1105, 112-119.[DOI:10.1016/j.aca.2020.01.027] Wang, X.-Y.; Xiong, C.-F.; Ye, T.-T.; Ding, J.; Feng, Y.-Q., Online polymer monolith microextraction with in-situ derivatization for sensitive detection of endogenous brassinosteroids by LC-MS. Microchemical Journal 2020, 158.[DOI:10.1016/j.microc.2020.105061] Xiao, H. M.; Liu, P.; Zheng, S. J; Wang, X.; Ding, J.; Feng, Y. Q, Screening of amino acids in dried blood spots by stable isotope derivatization-liquid chromatography-electrospray ionization mass spectrometry. Chinese Chemical Letters 2020.[DOI10.1002/bmc.4756] Cheng, M. Y.; Tao, W. B.; Yuan, B. F.; Feng, Y. Q., Methods for isolation of messenger RNA from biological samples. Anal Methods-Uk2020.[DOI: 10.1039/d0ay01912g] Fang, W.; Zhang, B.; Han, F. Y.; Qin, Z. N.; Feng, Y. Q.; Hu, J. M.; Shen, A. G., On-Site and Quantitative Detection of Trace Methamphetamine in Urine/Serum Samples with a Surface-Enhanced Raman Scattering-Active Microcavity and Rapid Pretreatment Device. Anal Chem2020, 92 (19), 13539-13549.[DOI: 10.1021/acs.analchem.0c03041] Feng, Y.; Xie, N.-B.; Tao, W.-B.; Ding, J.-H.; You, X.-J.; Ma, C.-J.; Zhang, X.; Yi, C.; Zhou, X.; Yuan, B.-F.; Feng, Y.-Q., Transformation of 5-Carboxylcytosine to Cytosine Through C–C Bond Cleavage in Human Cells Constitutes a Novel Pathway for DNA Demethylation. CCS Chemistry2020, 994-1008.[DOI: 10.31635/ccschem.020.202000286] Qin, Z. N.; Chen, X.; Yu, Q. W.; Ding, J.; Feng, Y. Q., Preparation of zirconium arsenate-modified monolithic column for selective enrichment of phosphopeptides. J Sep Sci2020.[DOI: 10.1002/jssc.202001051] Qin, Z.-N.; Yu, Q.-W.; Zhou, P.; Feng, Y.-Q., C60-based chemical labeling strategy for the determination of polyamines in biological samples using matrix-assisted laser desorption/ionization mass spectrometry. Talanta2020.[DOI: 10.1016/j.talanta.2020.121790] Wei, L.; Fu, P.; Chen, X.; An, N.; Yue, S.; Ren, H.; Zhao, W.; Xie, Q.; Sun, Y.; Zhu, Q.-F.; Wang, Z.; Feng, Y.-Q., Quantitative Determination of Hydroxymethanesulfonate (HMS) Using Ion Chromatography and UHPLC-LTQ-Orbitrap Mass Spectrometry: A Missing Source of Sulfur during Haze Episodes in Beijing. Environmental Science & Technology Letters2020, 7 (10), 701-707.[DOI: 10.1021/acs.estlett.0c00528] Ye, T.; Wang, Y.; Feng, Y. Q.; Chan, Z., Physiological and metabolomic responses of bermudagrass (Cynodon dactylon) to alkali stress. Physiol Plant 2020.[DOI: 10.1111/ppl.13209] Zhu, Q. F.; An, N.; Feng, Y. Q., In-Depth Annotation Strategy of Saturated Hydroxy Fatty Acids Based on Their Chromatographic Retention Behaviors and MS Fragmentation Patterns. Anal Chem2020, 92 (21), 14528-14535.[DOI: 10.1021/acs.analchem.0c02719] Xu, J., Zhang, Q. F., Zheng, J., Yuan, B. F., and Feng, Y. Q. (2019) Mass spectrometry-based fecal metabolome analysis, TrAC-Trend Anal Chem. [DOI:10.1016/ j.trac.2018.12.027] Chen, B.; Yuan, B. F.; Feng, Y. Q., Analytical Methods for Deciphering RNA Modifications. Anal Chem 2019. [DOI:10.1021/acs.analchem.8b04078] Lan, M.-D.; Yuan, B.-F.; Feng, Y.-Q., Deciphering nucleic acid modifications by chemical derivatization-mass spectrometry analysis. Chinese Chem Lett 2019. [DOI:10.1016/j.cclet.2018.04.021] You, X. J.; Liu, T.; Ma, C. J.; Qi, C. B.; Tong, Y.; Zhao, X.; Yuan, B. F.; Feng, Y. Q., Determination of RNA Hydroxylmethylation in Mammals by Mass Spectrometry Analysis. Anal Chem 2019, 91 (16), 10477-10483. [DOI:10.1021/acs.analchem.9b01318] Xiong, J., Ye, T. T., Ma, C. J., Cheng, Q. Y., Yuan, B. F., and Feng, Y. Q. (2019) N6-Hydroxymethyladenine: a hydroxylation derivative of N6-methyladenine in genomic DNA of mammals, Nucleic Acids Res. [DOI:10.1093/nar/gky1218] Hu, M.-M.; He, W.-R.; Gao, P.; Yang, Q.; He, K.; Cao, L.-B.; Li, S.; Feng, Y.-Q.; Shu, H.-B., Virus-induced accumulation of intracellular bile acids activates the TGR5-β-arrestin-SRC axis to enable innate antiviral immunity. Cell Research 2019. [DOI:10.1038/s41422-018-0136-1] Luo, X. T.; Cai, B. D.; Jiang, H. P.; Xiao, H. M.; Yuan, B. F.; Feng, Y. Q., Sensitive analysis of trehalose-6-phosphate and related sugar phosphates in plant tissues by chemical derivatization combined with hydrophilic interaction liquid chromatography-tandem mass spectrometry. J Chromatogr A 2019. [DOI:org/10.1016/j.chroma.2019.01.040] Xiao, H. M.; Wang, X.; Yang, X.; Zheng, F.; Feng, Y. Q., Hydralazine derivative of aldehyde: A new type of [M-H](+) ion formed in electrospray ionization mass spectrometry. J Mass Spectrom 2019. [DOI:10.1002/jms.4330] Cai, W. J.; Yu, L.; Wang, W.; Sun, M.; Feng, Y. Q., Simultaneous determination of multi-class phytohormones in sub-milligram plant samples by one-pot multi-functional derivatization assisted liquid chromatography-tandem mass spectrometry. Anal Chem 2019. [DOI:10.1021/acs.analchem.8b05087] Yu, L.; Cai, W. J.; Ye, T.; Feng, Y. Q., A new boronic acid reagent for the simultaneous determination of C27-, C28-, and C29-brassinosteroids in plant tissues by chemical labeling-assisted liquid chromatography-mass spectrometry. Anal Bioanal Chem 2019. [DOI:10.1007/s00216-019-01612-9] Zheng, F.; Xiao, H. M.; Zhu, Q. F.; Yu, Q. W.; Feng, Y. Q., Profiling of benzimidazoles and related metabolites in pig serum based on SiO2@NiO solid-phase extraction combined precursor ion scan with high resolution orbitrap mass spectrometry. Food Chem 2019, 284, 279-286. [DOI:10.1016/j.foodchem.2019.01.071] Qi, C. B; Ding, J. H; Yuan, B. F; Feng, Y. Q, Analytical methods for locating modifications in nucleic acids. Chinese Chemical Letters 2019.[DOI: 10.1016/j.cclet.2019.02.005 ] Tang, F.; Liu, S.; Li, Q. Y.; Yuan, J.; Li, L.; Wang, Y.; Yuan, B. F.; Feng, Y. Q., Location analysis of 8-oxo-7,8-dihydroguanine in DNA by polymerase-mediated differential coding. Chem Sci 2019, 10 (15), 4272-4281.[DOI: 10.1039/C8SC04946G] Zheng, J.; Zheng, S. J.; Cai, W. J.; Yu, L.; Yuan, B. F.; Feng, Y. Q., Stable isotope labeling combined with liquid chromatography-tandem mass spectrometry for comprehensive analysis of short-chain fatty acids. Anal Chim Acta 2019, 1070, 51-59.[DOI: 10.1016/j.aca.2019.04.021] Zhu, Q. F.; Zhang, T. Y.; Qin, L. L.; Li, X. M.; Zheng, S. J.; Feng, Y. Q., Method to Calculate the Retention Index in Hydrophilic Interaction Liquid Chromatography Using Normal Fatty Acid Derivatives as Calibrants. Anal Chem 2019, 91 (9), 6057-6063.[DOI: 10.1021/acs.analchem.9b00598] Xiong, J.; Yuan, B. F.; Feng, Y. Q., Mass Spectrometry for Investigating the Effects of Toxic Metals on Nucleic Acid Modifications. Chem Res Toxicol 2019, 32 (5), 808-819.[DOI: 10.1021/acs.chemrestox.9b00042] Zheng, J.; Zheng, S. J.; Qi, C. B.; Wu, D. M.; Feng, Y. Q., 4-Plex Chemical Labeling Strategy Based on Cinchona Alkaloid-Derived Primary Amines for the Analysis of Chiral Carboxylic Acids by Liquid Chromatography-Mass Spectrometry. Anal Chem 2019, 91 (17), 11440-11446.[DOI:10.1021/acs.analchem.9b02909] Ma, C. J.; Ding, J. H.; Ye, T. T.; Yuan, B. F.; Feng, Y. Q., ALKBH1 demethylates N3-methylcytidine in mRNA of mammals. ACS Chem Biol 2019.[DOI: 10.1021/acschembio.8b01001] Xiao, H. M.; Wang, X.; Liao, Q. L.; Zhao, S.; Huang, W. H.; Feng, Y. Q., Sensitive analysis of multiple low-molecular-weight thiols in a single human cervical cancer cell by chemical derivatization-liquid chromatography-mass spectrometry. Analyst 2019, 144 (22), 6578-6585.[DOI: 10.1039/c9an01566c] Chen, Y. S.; Xiao, H. M.; Wang, T. Q.; Yu, L.; Feng, Y. Q., A boronic acid modified binary matrix consisting of boron nitride and alpha-cyano-4-hydroxycinnamic acid for determination of cis-diols by MALDI-TOF MS. Mikrochim Acta 2019, 186 (8), 591.[DOI:10.1007/s00604-019-3711-3] Chen, B.; Xiong, J.; Ding, J. H.; Yuan, B. F.; Feng, Y. Q., Analysis of the Effects of Cr(VI) Exposure on mRNA Modifications. Chem Res Toxicol 2019, 32 (10), 2078-2085.[DOI:10.1016/j.aca.2019.11.016] He, K.; Wang, Y. L.; Zhu, Q. F.; Cheng, L. M.; Feng, Y. Q., Profiling thiol metabolites in myocardial infarction human serum by stable isotope labeling assisted liquid chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2019, 1126-1127, 121738.[DOI:10.1016/j.jchromb.2019.121738] Yu, Q. W; Liu, S. J; Zheng, F.; Xiao, H. M; Guan, H. Y; Feng, Y. Q, Identification and quantification of benzimidazole metabolites of thiophonate-methyl sprayed on celery cabbage using SiO2@NiO solid-phase extraction in combination with HPLC-MS/MS. Chinese Chemical Letters 2019.[DOI:10.1016/j.cclet.2019.07.065] Zhang, Y. F.; Qi, C. B.; Yuan, B. F.; Feng, Y. Q., Determination of cytidine modifications in human urine by liquid chromatography - Mass spectrometry analysis. Anal Chim Acta 2019, 1081, 103-111.[DOI:10.1016/j.aca.2019.07.002] Zhang, T.-Y.; Li, S.; Zhu, Q.-F.; Wang, Q.; Hussain, D.; Feng, Y.-Q., Derivatization for liquid chromatography-electrospray ionization-mass spectrometry analysis of small-molecular weight compounds. TrAC Trends in Analytical Chemistry 2019, 119 .[DOI:10.1016/j.trac.2019.07.019] Zheng, S. J.; Zheng, J.; Xiao, H. M.; Wu, D. M.; Feng, Y. Q., Simultaneous quantitative analysis of multiple sphingoid bases by stable isotope labeling assisted liquid chromatography-mass spectrometry. Anal Chim Acta 2019, 1082, 106-115.[DOI:https://doi.org/10.1016/j.aca.2019.07.016]

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