研究领域
1.生物活性天然产物(包括中药)先导化合物及其结构修饰; 2.抗骨质疏松,抗风湿性关节炎药物研究; 3.药物代谢研究; 4.生物核磁共振技术。
近期论文
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Synthesis of a novel series of diphenolic chromone derivatives as inhibitors of NO production in LPS-activated RAW264.7 macrophages, Bioorganic & Medicinal Chemistry, 2010, 18, 2864-2871.
Synthesis and evaluation of a novel series of quinoline derivatives with immunosuppressive activity, Bioorganic & Medicinal Chemistry, 2009, 17, 5433–5441.
The pH dependent, stereoselective dimerization of sinomenine, Organic Letters, 2008, 10(17), 3879–3882.
Biocatalyzed cross-coupling of sinomenine and guaiacol by Antrodiella semisupina, Organic Letters, 2008, 10(6), 1119–1122.