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个人简介

现任南京大学教授,研究生院副院长。1984年本科毕业于南京大学化学系,1993年在南京大学获得博士学位,1998-1999年在以色列巴伊兰大学从事博士后研究。2001年晋升为教授,2002年任博士研究生导师。 2003年获得国家杰出青年科学基金。主要工作涉及生物纳米电化学、纳米与生物成像、纳米材料的生物应用等。近年来,在基于纳米探针的光学显微成像技术开发、面向肿瘤的纳米诊疗系统的构建以及基于纳米材料的新型生物燃料电池研究等方面取得了一系列创新性成果。相关研究成果在Nat. Chem.、Nat. Commun.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Chem. Soc. Rev.、Adv. Mater.等期刊上发表,共发表SCI论文400多篇,他引18000多次,H-index为81,连续四年入选爱思唯尔(2014、2015、2016、2017)中国高被引学者榜单,一篇发表在NANO LETTERS,(2012,12(2):844-849)上的论文被选为2012年中国百篇最具影响国际学术论文,同时也是英国皇家化学会会士,Analyst副主编。编写专著Quantum Dots for DNA Biosensing (Springer ISSN 2191-540, DOI 10.1007/978-3-642-44910-, 2013)和《纳米分析化学》(科学出版社,2014)。编写世界第一部《Encyclopedia of NANOSCIENCE and NANOTECHNOLOGY》专章1章(2004,美国科学出版社),《Comprehensive Sampling and Sample Preparation》专章1章(2012,Elsevier出版社)和《Encyclopedia of SEMICONDUCTOR NANOTECHNOLOGY》专章1章(2017,美国科学出版社),作为共同主编参与编写专著《Fabrication and Bio-application of Functionalized Nanomaterials》(2009, Research Signpost) 及《Nanocarbons for Electroanalysis》(2017, Wiley)。现在或曾承担了国家自然科学基金委重大国际合作项目、重点项目和重大科研仪器研制项目,国家重大研究计划纳米科技专项课题,科技部国际合作项目,欧盟第六框架课题等。

研究领域

功能纳米材料的制备及其表界面性质的研究 纳米仿生材料的组装与光电分析化学 基于纳米材料的芯片分析

近期论文

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Zhang, Z.; Xu, H;Fan, Y.; Zhang, X.;Wang, W.; Zhu, J.-J.; Min, Q.-H. Mass Nanotags Mediate Parallel Amplifications on Nanointerfaces for Multiplexed Profiling of RNAs. Nano Lett. 2023, 23 (5), 1820-1829. Zhang, Y.; Luo, D.; Zhang, Y.; Zhang, Q.-H.; Ji, Q.-Y.; Zhou, S.-K.; Huang, S.; Li, L.-L.; Lu, F.; Yao, W.-F.; Cheng F.-F.; Zhu, J.-J.; Zhang L.. DNAzymes-Conjugated Upconversion Nanoamplicon for In-Situ Ultrasensitive Detection and Imaging of MicroRNA in Vivo. Chem. Eng. J. 2023, 454. Zhang, Q.; Xu, S.; Zheng, J.; Zhang, J.-R.; Zhu, J.-J. Advances in Self-Assembled Au-DNA Nanomachines. iScience 2023, 26 (4), 106327. Yu, S.; Sun, Y.; Cai, J.; Zhou, Y.; Zhu, J.-J. A Separable Nanodevice Enables Multilayer Imaging of Diverse Biomarkers for Precise Diagnosis. Chem. Commun. 2023, 59 (23), 3419-3422. Yang, G.-H.; Liu, F.-L.; Zhao, J.-Y.; Fu, L.-J.; Gu, Y.-Q.; Qu, L.-L.; Zhu, C.-Z.; Zhu, J.-J.; Lin, Y.-H. MXenes-Based Nanomaterials for Biosensing and Biomedicine. Coord. Chem. Rev. 2023, 479. Wang, L.; Zhu, W.; Zhang, J.; Zhu, J.-J.Miniaturized Microfluidic Electrochemical Biosensors Powered by Enzymatic Biofuel Cell. Biosensors (Basel)2023,13 (2). Ma, C.; Zhang, Z.; Tan, T.; Zhu, J.-J. Recent Progress in Plasmonic Based Electrochemiluminescence Biosensors: A Review. Biosensors (Basel) 2023, 13 (2). Liu, Z.; Feng, Z.-Y.; Chen, M.-H.; Zhan, J.-Y.; Wu, R.; Shi, Y.; Xue, Y.-S.; Liu, R.; Zhu, J.-J.; Zhang, J.-J. An Orthogonally Activatable CRISPR-Cas13d Nanoprodrug to Reverse Chemoresistance for Enhanced Chemo-Photodynamic Therapy. Chem. Sci. 2023. Liu, L.-X.; Cai, Y.; Du, H.; Lu, X.; Li, X.; Liu, F.; Fu, J.; Zhu, J.-J. Enriching the Local Concentration of CO Intermediates on Cu Cavities for the Electrocatalytic Reduction of CO(2) to C(2+) Products.ACS Appl. Mater. Interfaces2023, 15 (13), 16673-16679. Li, Z.; Tan, J.; Gao, C.; Lu, Z.; You, J.; Zhu, J.-J. Polarity-Ultrasensitive and Lipophilicity-Enhanced Structurally Modified Hemicyanine for Two-Color Staining to Reveal Cell Apoptosis during Chemotherapy. Anal. Chem. 2023, 95 (3), 2011-2019. Huang, S.; Song, Y.; Zhang, J.-R.; Chen, X.; Zhu, J.-J.Antibacterial Carbon Dots-Based Composites. Small 2023. Han, T.-T.; Cao, Y.; Wang, J.; Jiao, J.-M.; Song, Y.; Wang, L.-Y.; Ma, C.; Chen, H.-Y.; Zhu, J.-J. Crystallization-Induced Enhanced Electrochemiluminescence from a New Tris(bipyridine)ruthenium(II) Derivative. Adv. Funct. Mater. 2023. Chu, Y.; Xiao, S.-J.; Zhu, J.-J. Rapid Signal Amplification Based on Planetary Cross-Catalytic Hairpin Assembly Reactions. Anal. Chem. 2023, 95 (9), 4317-4324. Cao, Y.; Wang, J.-X.; Lin, C.; Geng, Y.-Q.; Ma, C.; Zhu, J.-J.; Wang, L.-Y.; Zhu, W.-L. Zwitterionic Electrochemiluminescence Biointerface Contributes to Label-Free Monitoring of Exosomes Dynamics in a Fluidic Microreaction Device. Adv. Funct. Mater. 2023. Zhang, Q.; Wang, Y.; Wang, W.; Min, Q.-H.; Zhang, J.-R.; Zhu, J.-J. A Telomerase-Assisted Strategy for Regeneration of DNA Nanomachines in Living Cells. Angew. Chem. Int. Ed. 2023, 62 (6). Lu, X.; Liu, Z.; Zhang, J.-R.; Zhou, Y.; Wang, L.; Zhu, J.-J. General Synergistic Hybrid Catalyst Synthesis Method Using a Natural Enzyme Scaffold-Confined Metal Nanocluster. ACS Appl. Mater. Interfaces 2023, 15 (1), 761-771. Jiang, Y.-J.; Hui, S.; Jiang, L.-P.; Zhu, J.-J. Functional Nanomaterial-Modified Anodes in Microbial Fuel Cells: Advances and Perspectives. Chem. Eur. J. 2023, 29 (1). Bai, Y.; Sun, X.; Dang, Y.; Yu, S.; Zhu, J.-J.; Zhou, Y. A Self-Circulating Electro-Fenton-Like Process Over Fe(3)O(4)-CaO(2) Cathode for Highly Efficient Degradation of Levofloxacin. Chemosphere 2023, 313. Zhu, J.-J.; Xia, H.; Son, Y.; Wu, X.; Tao, Y.; Anandan, S. Special Issue on Sonochemistry in Asia 2021''. Ultrason. Sonochem. 2022, 87. Zhu, H.; Li, X.; He, Z.; Chen, Y.; Zhu, J.-J. Metal Azolate Coordination Polymer-Enabled High Payload and Non-Destructive Enzyme Immobilization for Biocatalysis and Biosensing. Anal. Chem. 2022, 94 (18), 6827-6832. Zhu, H.; Chen, Z.; Chen, Y.; Zhu, J.-J. Affinities and Kinetics Detection of Protein-Small Molecule Interactions with a Monolayer MoS(2) -Based Optical Imaging Platform. Small 2022, 18 (29). Zhang, Z.; Ma, C.; Xu, Q.; Zhu, J.-J. Recent Progress in Electrochemiluminescence Microscopy Analysis of Single Cells. Analyst 2022, 147 (13), 2884-2894. Zhang, Y.; Luo, D.; Zhou, S.-K.; Yang, L.; Yao, W.-F.; Cheng, F. F.; Zhu, J.-J.; Zhang, L. Analytical and Biomedical Applications of Nanomaterials in Chinese Herbal Medicines Research. Trac-Trend, Anal, Chem. 2022, 156. Zhang, X.; Lu, W.; Ma, C.; Wang, T.; Zhu, J.-J.; Zare, R. N.; Min, Q. Insights into Electrochemiluminescence Dynamics by Synchronizing Real-Time Electrical, Luminescence, and Mass Spectrometric Measurements. Chem. Sci. 2022, 13 (21), 6244-6253. Zhan, J.; Liu, Z.; Liu, R.; Zhu, J.-J.; Zhang, J. Near-Infrared-Light-Mediated DNA-Logic Nanomachine for Bioorthogonal Cascade Imaging of Endogenous Interconnected MicroRNAs and Metal Ions. Anal. Chem. 2022, 94 (48), 16622-16631. Yu, S.; Zhang, R.-R.; Dang, Y.; Zhou, Y.-Z.; Zhu, J.-J. Electrochemical Activation of Peroxymonosulfate at Ti/La2O3-PbO2 Anode to Enhance the Degradation of Typical Antibiotic Wastewater. Sep. Purif. Technol. 2022, 294. Yu, S.; Zhang, Q.-Y.; Sun, X.-Q.; Chen, S.-L.; Tang, J. L.; Zhu, J.-J.; Dang, Y. Doping Sb into CuFe2O4 Improved the Catalytic Performance in the Electrochemically Enhanced Homogeneous Peroxymonosulfate-Heterogeneous Catalytic System for the Degradation of Ciprofloxacin. J. Environ. Chem. Eng. 2022, 10 (5). Yu, S.; Wu, Y.; Xue, Q.; Zhu, J.-J.; Zhou, Y.-Z. A Novel Multi-Walled Carbon Nanotube-Coupled CoNi MOF Composite Enhances the Oxygen Evolution Reaction Through Synergistic Effects. J. Mater. Chem. A 2022, 10 (9), 4936-4943. Yu, S.; Chen, S.; Dang, Y.; Zhou, Y.; Zhu, J.-J. An Ultrasensitive Electrochemical Biosensor Integrated by Nicking Endonuclease-Assisted Primer Exchange Reaction Cascade Amplification and DNA Nanosphere-Mediated Electrochemical Signal-Enhanced System for MicroRNA Detection. Anal. Chem. 2022, 94 (41), 14349-14357. Yimamumaimaiti, T.; Su, Q.; Song, R.-B.; Gao, Y.; Yu, S.; Tan, T.; Wang, L.; Zhu, J.-J.; Zhang, J.-R. Damage-Free and Time-Saving Platform Integrated by a Flow Membrane Separation Device and a Dual-Target Biofuel Cell-Based Biosensor for Continuous Sorting and Detection of Exosomes and Host Cells in Human Serum. Anal. Chem. 2022, 94 (21), 7722-7730. Yang, L.; Zhu, S. D.; He, Z.-M.; Li, X.-L.; Chen, J.-N.; Bi, S.; Zhu, J.-J. Aqueous-Phase Synthesis of Upconversion Metal-Organic Frameworks for ATP-Responsive in Situ Imaging and Targeted Combinational Cancer therapy. Chin. Chem. Lett. 2022, 33 (1), 314-319. Yang, L.; Yu, S.; Yan, Y.; Bi, S.; Zhu, J.-J. Upconversion Nanoparticle@Au Core-Satellite Assemblies for In Situ Amplified Imaging of MicroRNA in Living Cells and Combined Cancer Phototherapy. Anal. Chem. 2022, 94 (19), 7075-7083. Xu, H.; Zhang, Z.; Wang, Y.; Zhang, X.; Zhu, J.-J.; Min, Q. Sense and Validate: Fluorophore/Mass Dual-Encoded Nanoprobes for Fluorescence Imaging and MS Quantification of Intracellular Multiple MicroRNAs. Anal. Chem. 2022, 94 (16), 6329-6337. Wu, R.; Yu, S.; Chen, S.; Dang, Y.; Wen, S. H.; Tang, J.; Zhou, Y.; Zhu, J.-J. A Carbon Dots-Enhanced Laccase-Based Electrochemical Sensor for Highly Sensitive Detection of Dopamine in Human Serum. Anal. Chim. Acta 2022, 1229. Wu, R.; Feng, Z.; Zhang, J.-J.; Jiang, L.-P.; Zhu, J.-J. Quantum Dots for Electrochemical Cytosensing. Trac-Trends in Analytical Chemistry 2022, 148. Wu, P.; Luo, X.; Xu, Y.; Zhu, J.; Jia, W.; Fang, N.; Cai, C.; Zhu, J.-J. Long-Range SERS Detection of the SARS-CoV-2 Antigen on a Well-Ordered Gold Hexagonal Nanoplate Film. Anal. Chem. 2022, 94 (50), 17541-17550. Wang, L.-L.; Zhang, J.-R.; Wu, X.-G.; Zhu, J.-J. Advances in The Enzymatic Biofuel Cell Powered Sensing Systems for Tumor Diagnosis and Regulation. Trac-Trends in Analytical Chemistry 2022, 146. Wang, L.; Su, Q.; Liu, Y.; Yimamumaimaiti, T.; Hu, D.; Zhu, J.-J.; Zhang, J.-R. A Self-Powered and Drug-Free Diabetic Wound Healing Patch Breaking Hyperglycemia and Low H(2)O(2) Limitations and Precisely Sterilizing Driven by Eectricity. Chem. Sci. 2022, 13 (41), 12136-12143. Tong, J.; Cao, Y.; Zhang, Y.-W.; Wang, P.; Wang, P.; Liao, X.-J.; Zhang, W.; Wang, Y.; Zheng, Y.-X.; Zhu, J.-J.; Pan Y.. Chiral-at-Cage Carboranes for Circularly Polarized Luminescence and Aggregation-Induced Electrochemiluminescence. Angew. Chem. Int. Ed. 2022, 61 (45), Tang, Z.; Liu, R.; Chen, X.; Gao, D.; Zhang, J.-R.; Zhu, J.-J.; Chen, Z. Plasmonic Probing Single-Cell Bio-Current Waves with a Shrinking Magnetite Nanoprobe. ACS Nano 2022, 16 (12), 20842-20850. Su, Y.; Yuan, B.; Jiang, Y.; Wu, P.; Huang, X.; Zhu, J.-J.; Jiang, L.-P. A Bioinspired Hollow g-C(3)N(4)-CuPc Heterostructure with Remarkable SERS Enhancement and Photosynthesis-Mimicking Properties for Theranostic Applications. Chem. Sci. 2022, 13 (22), 6573-6582. Qing, S.-L.; Wang, L.-L.; Jiang, L.-P.; Wu, X. G.; Zhu, J.-J. Live Microalgal Cells Modified by L-cys/Au@carbon Dots/bilirubin Oxidase Layers for Enhanced Oxygen Reduction in A Membrane-Less Biofuel Cell. Smartmat 2022, 3 (2), 298-310. Ma, C.; Zheng, T.; Zhang, R.; Zhu, J.-J. Editorial: Optical and Electrochemical Biosensing. Front Chem 2022, 10. Ma, C.; Xing, Z.; Gou, X.; Jiang, L.-P.; Zhu, J.-J. A Temperature-Tuned Electrochemiluminescence layer for Reversibly Imaging Cell Topography. Chem. Sci. 2022, 13 (46), 13938-13947. Liu, Z.; Zhu, J.-J. Celebrating 100 Years of Chemistry at Nanjing University. Analyst 2022, 147 (13), 2883. Li, W.-T.; Dong, S.-Y.; Chen, H.; An, Y.-Q.; Zhang, J.; Wang, L. Y.; Zhu, J.-J. A Neurofilament-Light Chains Electrochemical Immunosensor Expected to Reveal the Early Stage of Neurodegenerative Diseases. Chem. Eng. J. 2022, 446. Li, J. X.; Chen, X.-Q.; Zhu, J.-J. DNA Functionalized Plasmonic Nanoassemblies as SERS Sensors for Environmental Analysis. Aggregate 2022. Jin, Z.; Liu, M.; Huang, X.; Zhang, X.; Qu, Z.; Zhu, J.-J.; Min, Q.-H. Top-Down Rational Engineering of Heteroatom-Doped Graphene Quantum Dots for Laser Desorption/Ionization Mass Spectrometry Detection and Imaging of Small Biomolecules. Anal. Chem. 2022, 94 (21), 7609-7618. Jiang, Y. W.; Tang, W. J.; Gao, G.; Geng, Y. Q.; Wu, F. G.; Min, Q.-H; Zhu, J.-J. Lipid Droplet-Hitchhiking Probe Creates Trojan Foam Cells for Fluorescence/Photoacoustic Imaging of Atherosclerotic Plaques. Biosens. Bioelectron. 2022, 216. Jiang, Y. J.; Hui, S.; Tian, S.; Chen, Z.; Chai, Y.; Jiang, L.-P.; Zhang, J.-R.; Zhu, J.-J. Enhanced Transmembrane Electron transfer in Shewanella Oneidensis MR-1 Using Gold Nanoparticles for High-Performance Microbial Fuel Cells. Nanoscale Adv. 2022, 5 (1), 124-132. Jiang, D.; Pan, Y.; Yao, H.; Sun, J.; Xiong, W.; Li, L.; Zheng, F.; Sun, S.; Zhu, J.-J. Synthesis of Renal-Clearable Multicolor Fluorescent Silicon Nanodots for Tumor Imaging and In Vivo H(2)O(2) Profiling. Anal. Chem. 2022, 94 (25), 9074-9080. Huang, S.; Song, Y.; Yao, H.; Min, Q.-H; Zhang, J.-R.; Zhu, J.-J. Multistage Photoactivatable Zinc-Responsive Nanodevices for Monitoring and Regulating Dysfunctional Islet beta-Cells. Anal. Chem. 2022, 94 (17), 6607-6614. Han, T.; Ma, C.; Wang, L.; Cao, Y.; Chen, H.-Y.; Zhu, J.-J. A Novel Electrochemiluminescence Janus Emitter for Dual‐Mode Biosensing. Adv. Funct. Mater. 2022, 32 (24). Ge, J.; Liang, J.; Chen, X.; Deng, Y.; Xiao, P.; Zhu, J.-J.; Wang, Y. Designing Inorganically Functionalized Magic-Size II-VI Clusters and Unraveling Their Surface States. Chem. Sci. 2022, 13 (40), 11755-11763. Fang, Y.; Yuan, B.; Jiang, Y.; Song, R.-B.; Zhang, J. R.; Zhu, J.-J. Layer-by-Layer Construction of in Situ Formed Polypyrrole and Bacterial Cells as Capacitive Bioanodes for Paper-Based Microbial Fuel Cells. J. Mater. Chem. A 2022, 10 (9), 4915-4925. Du, H.; Fu, J.; Liu, L. X.; Ding, S.; Lyu, Z.; Chang, Y. C.; Jin, X.; Kengara, F. O.; Song, B.; Min, Q.-H.; Zhu, J.-J.; Du D.,; Gu C.; Lin Y. H.,; Hu J.-S.; Zhu W. L. Recent Progress in Electrochemical Reduction of Carbon Monoxide Toward Multi-Carbon Products. Mater. Today 2022, 59, 182-199. Dong, Y.; Liu, J.; Lu, X.; Duan, J.; Zhou, L.; Dai, L.; Ji, M.; Ma, N.; Wang, Y.; Wang, P.; Zhu, J.-J.;Min, Q, Gang O.; Tian Y. Two-Stage Assembly of Nanoparticle Superlattices with Multiscale Organization. Nano Lett. 2022, 22 (9), 3809-3817. Dong, Y.; Jin, Z.; Zhang, X.; Tang, Y.; Tian, Y.; Zhu, J.-J.; Min, Q.-H.. A Six-Plex Switchable DNA Origami Cipher Disk for Tandem-in-Time Cryptography. Chem. Commun. 2022, 58 (41), 6124-6127. Chen, X.; Gao, Y.; Zhan, J.; Xia, Q.; Chen, Z.; Zhu, J.-J. Spatiotemporal-Resolved Hyperspectral Raman Imaging of Plasmon-Assisted Reactions at Single Hotspots. Anal. Chem. 2022, 94 (23), 8174-8180. Cao, Y.; Zhou, J. L.; Ma, Y.; Zhou, Y.; Zhu, J.-J. Recent Progress of Metal Nanoclusters in Electrochemiluminescence. Dalton T. 2022, 51 (23), 8927-8937. Algar, W. R.; Albrecht, T.; Faulds, K.; Zhu, J.-J. Analytical Nanoscience. Analyst 2022, 147 (5), 765-766.

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