江德臣 - 南京大学 - 化学化工学院

个人简介

南京大学化学化工学院及生命分析化学国家重点实验室教授，博士生导师，国家杰出青年基金获得者（2020），教育部青年长江学者（2017）。于2000、2003和2008年分别在南京大学、复旦大学和美国凯斯西储大学获学士、硕士和博士学位。工作经历 2008年10月至2011年5月在美国北卡莱罗拉州大学教堂山分校从事博士后研究。2011年5月加入南京大学化学化工学院，任单细胞分析课题组长。

研究领域

课题组致力于发展新型电化学方法及装置，实现通用型的单细胞和亚细胞分析，为单细胞异质性研究提供研究工具和科学数据。

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Pan RR*, Wang DC, Liu K, Chen HY, Jiang DC*. Electrochemical molecule trap-based sensing of low-abundance enzymes in one living cell. J. Am. Chem. Soc. 2022, 144, 17558-17566. Liu K, Liu RJ, Wang DC, Pan RR*, Chen HY, Jiang DC*. Spatial analysis of reactive oxygen species in a 3D cell model using a sensitive nanocavity electrode. Anal. Chem. 2022, 94, 13287-13292. Yang F, Jin R, Jiang DC*. High spatial resolution imaging of the charge injection yield at hematite using scanning electrochemical cell microscopy. Electrochem. commun. 2022, 141, 107358. Dong XR, Huang YC, Jiang DC*. Fluorescent polymerase chain reaction nanokit for the detection of DNA sequence in single living cells. Anal. Chem. 2022, 94, 10304-10307. Chang XQ, Wang NN, Jiang DP*, Chen HY, Jiang DC*. Nanokit coupled electrospray ionization mass spectrometry for analysis of angiotensin converting enzyme 2 activity in single living cell. Chin. Chem. Lett. 2022, DOI: 10.1016/j.cclet.2022.05.036 Liu YL, Fan JH, Zhang N, Xu HY, Su W, Qin Y, Jiang DC*. Trihexyltetradecylphosphonium chloride based ratiometric fluorescent nanosensors for multiplex anion discrimination. Analyst 2022, 147, 3209-3218. Knežević S, Bouffier L, Liu BH*, Jiang DC*, Sojic N*. Electrochemiluminescence microscopy: from single objects to living cells. Curr. Opin. Electrochem. 2022, 35, 101096. Li Y, Jin R, Xu LF, Jiang DP*, Chen HY, Jiang DC*. Electrochemically imaging the response of ion-selective membranes with an ultralow detection limit. ACS Appl. Mater. Interfaces 2022, 14, 14097-14102. Li DR, Wang NN, Zhang TY, Wu GX, Xiong YF, Du QQ, Tian YF, Zhao WW, Ye JD, Gu SL, Lu YQ, Jiang DC*, Xu F*. Label-free fiber nanograting sensor for real-time in situ early monitoring of cellular apoptosis. Adv. Photonics 2022, 4, 016001. Xu LF, Li Y, Jin R, Jiang DP*, Jiang DC*. High spatial resolution observation of Temporin A at cell membranes using scanning ion conductive microscopy. Electrochem. commun. 2022, 134, 107181. Cheng L, Jin R, Jiang DC*, Zhuang J*, Liao XB, Zheng QQ. Scanning electrochemical cell microscopy platform with local electrochemical impedance spectroscopy. Anal. Chem. 2021, 93, 16401-16408. Zhu H, Jin R, Chang YC, Zhu JJ, Jiang DC, Lin YH*, Zhu WL*. Understanding the synergistic oxidation in dichalcogenides through electrochemiluminescence blinking at millisecond resolution. Adv. Mater. 2021, 33, 2105039. Liu YJ, Zhang HD, Li BX, Liu JW, Jiang DC*, Liu BH*, Sojic N*. Single biomolecule imaging by electrochemiluminescence. J. Am. Chem. Soc.2021, 143, 17910-17914. Xu YY, Liu K, Jin R, Jiang DC*, Fang DJ*. Dynamic visualization of free radicals at single oxygen bubble using chemiluminescence. Chem. Asian J. 2021, 16, 4049-4052. Wang NN, Pan RR, Ji LN*, Jiang DC*, Chen HY. Photoelectrochemical analysis of the alkaline phosphatase activity in single living cells. Analyst 2021, 146, 5528-5532. Wang NN, Wang DN, Pan RR, Wang DC*, Jiang DC*, Chen HY. Self-referenced nanopipette for electrochemical analysis of hydrogen peroxide in the nucleus of a single living cell. Anal. Chem. 2021, 93, 10744-10749. Jin R, Lu Hy, Cheng L, Zhuang J, Jiang DC*, Chen HY. Highly spatial imaging of electrochemical activity on the wrinkles of graphene using all-solid scanning electrochemical cell microscopy. Fundam. Res. 2022, 2, 193-197. Wang YL, Pan RR, Jiang DP*, Jiang DC*, Chen HY. Nanopipettes for the electrochemical study of enhanced enzymatic activity in a femtoliter space. Anal. Chem. 2021, 93, 14521-14526. Wang YL, Jiang DC*, Chen HY. Wireless electrochemical-visualization of intracellular antigens at single cells. CCS Chem. 2021, 3, 2268-2274. Chen Y, Gou XD, Ma C*, Jiang DC*, Zhu JJ. A synergistic coreactant for single-cell electrochemiluminescence imaging: guanine-rich ssDNA-Loaded high-index faceted gold nanoflowers. Anal. Chem. 2021, 93, 7682-7689. Jin R, Cheng L, Lu HY, Zhuang J*, Jiang DC*, Chen HY. High spatial resolution electrochemical microscopic observation of enhanced charging under bias at active sites of N-rGO. ACS Appl. Energy Mater. 2021, 4, 3502-3507. Zhu H, Jiang DC*, Zhu JJ*. High-resolution imaging of catalytic activity of a single graphene sheet using electrochemiluminescence microscopy. Chem. Sci. 2021, 12, 4794-4799. Cui C, Jin R, Jiang DC*, Zhang JR*, Zhu JJ*. Visualization of an accelerated electrochemical reaction under an enhanced electric field. Research 2021, 2021, 1-9. Zhang JJ, Jin R, Chen Y, Fang DJ*, Jiang DC*. Enhanced electrochemiluminescence at single lithium iron phosphate nanoparticles for the local sensing of hydrogen peroxide efflux from single living cell under a low voltage. Sens. Actuators B Chem. 2021, 329, 129208. Huang RC, Jin R, Jiang DC*, Chen HY. Single-cell-resolved measurement of enzyme activity at the tissue level using drop-on-demand microkits. Analyst 2021, 146, 1548-1551. Qian YZ, Li Y, Qin Y, Jiang DC*, Chen HY. Ion-selective polymer dots for photoelectrochemical detection of potassium ions. Analyst 2021, 146, 450-453. Wang YL, Jiang DC*, Chen HY. Electrochemiluminescence analysis of hydrogen peroxide using L012 modified electrodes. JOAT 2020, 4, 122-127. Zhang JJ, Jin R, Fang DJ*, Jiang DC*. Voltage modulated electrochemiluminescence for highly sensitive detection. Chem J. Chinese U. 2020, 41, 2421-2425. Li Y, Feng JJ, Huang YC, Qin Y, Jiang DC*, Chen HY. Upconverting ion-selective nanoparticles for the imaging of intracellular calcium ions. Analyst 2020, 145, 4768-4771. Liu GN, Kolodziej C, Jin R, Qi SP, Lou YB*, Chen JX, Jiang DC*, Zhao YX*, Burda C*. MoS2-stratified CdS-Cu2-xS core-shell nanorods for highly-efficient photocatalytic hydrogen production. ACS Nano 2020, 14, 5468-5479. Wang YL, Jin R, Sojic N*, Jiang DC*, Chen HY. Intracellular wireless analysis of single cells by bipolar electrochemiluminescence confined in a nanopipette. Angew. Chem. Int. Ed.2020, 59, 10416-10420. Pan RR, Hu KK, Jia R, Rotenberg SA, Jiang DC*, Mirkin MV*. Resistive-pulse sensing inside single living cells. J. Am. Chem. Soc. 2020, 142, 5778-5784. Jin R, Huang YC, Cheng L, Lu HY, Jiang DC*, Chen HY. In situ observation of heterogeneous charge distribution at the electrode unraveling the mechanism of electric field-enhanced electrochemical activity. Chem. Sci. 2020, 11, 4158-4163. Cui C, Jin R, Jiang DC*, Zhang JR*, Zhu JJ*. Electrogenerated chemiluminescence in submicron wells for very-high-density biosensing. Anal. Chem. 2020, 92, 578-582. Gao TB, Zhang JJ, Wen J, Yang XX, Ma HB, Cao DK*, Jiang DC*. Single-molecule microRNA electrochemiluminescence detection using cyclometalated dinuclear Ir(III) complex with synergistic effect. Anal. Chem. 2020, 92, 1268-1275. Li Y, Chen FZ, Xu YT, Yu WH, Li HY*, Fan GC, Han DM, Zhao WW*, Jiang DC*. Self-assembled peptide nanostructures for photoelectrochemical bioanalysis application: a proof-of-concept study. Anal. Chem. 2019, 91, 12606-12610. Pan RR, Hu KK, Jiang DC*, Samuni U, Mirkin MV*. Electrochemical resistive-pulse sensing. J. Am. Chem. Soc. 2019, 141, 19555-19559. Zhu H, Jin R, Jiang DC*, Zhu JJ*. Perturbation electrochemiluminescence imaging to observe the fluctuation of charge-transfer resistance at individual graphene microsheets with redox-induced defects. ACS Appl. Mater. Interfaces 2019, 11, 46666-46670. Pan RR, Jiang DC*. Nanokits for the electrochemical quantification of enzyme activity in single living cells. Meth. Enzymol. 2019, 628, 173-189. Zhang JJ, Jin R, Jiang DC*, Chen HY. Electrochemiluminescence-based capacitance microscopy for label-free imaging of antigens on the cellular plasma membrane. J. Am. Chem. Soc.2019, 141, 10294-10299. Xu HY, Yang DD, Jiang DC*, Chen HY. Phosphate assay kit in one cell for electrochemical detection of intracellular phosphate ions at single cells. Front. Chem. 2019, 7, 1-6. Chen Y, Zhao DB, Fu JJ, Gou XD, Jiang DC*, Dong H*, Zhu JJ*. In situ imaging facet-induced spatial heterogeneity of electrocatalytic reaction activity at the subparticle level via electrochemiluminescence microscopy. Anal. Chem. 2019, 91, 6829-6835. Zhang JJ, Arbault S, Sojic N*, Jiang DC*. Electrochemiluminescence imaging for bioanalysis. Annu. Rev. Anal. Chem.2019, 12, 275-295. Zhang JJ, Ding H, Zhao S, Jiang DC*, Chen HY. Confined electrochemiluminescence in vertically ordered silica mesochannels for the imaging of hydrogen peroxide released from single cells. Electrochem. Commun. 2019, 98, 38-42. Jin R, Ye XD, Fan JP, Jiang DC*, Chen HY. In situ imaging of photocatalytic activity at titanium dioxide nanotubes using scanning ion conductance microscopy. Anal. Chem. 2019, 91, 2605-2609. Huang SH, Liu K, Jiang DC, Fang DJ*. Codetermination of sphingomyelin and cholesterol in cellular plasma membrane in sphingomyelin-depletion-induced cholesterol efflux. Anal. Chem. 2019, 91, 1501-1506. Cui C, Chen Y, Jiang DC*, Chen HY, Zhang JR*, Zhu JJ*. Steady-state electrochemiluminescence at single semiconductive titanium dioxide nanoparticles for local sensing of single cells. Anal. Chem. 2019, 91, 1121-1125. Tao L, Qiao M, Jin R, Li Y, Xiao ZH, Wang YQ, Zhang NN, Xie C, He QG, Jiang DC, Yu G*, Li YF*, Wang SY*. Bridging the surface charge and catalytic activity of a defective carbon electrocatalyst. Angew. Chem. Int. Ed. 2019, 58, 1019-1024. Xu MC, Pan RR, Zhu Y, Jiang DC*, Chen HY*. Molecular profiling of single axons and dendrites in living neurons using electrosyringe-assisted electrospray mass spectrometry. Analyst 2019, 144, 954-960. Xu MC, Pan RR, Zhu Y, Jiang DC*, Chen HY*. Resistive analysis of hydrogen peroxide in one axon of single neuron with nanopipets. Anal. Chem. 2018, 90, 10117-10121. Chen Y, Fu JJ, Cui C, Jiang DC*, Chen ZX*, Chen HY, Zhu JJ*. In situ visualization of electrocatalytic reaction activity at quantum dots for water oxidation. Anal. Chem. 2018, 90, 8635-8641. Zhou JY, Jiang DC*, Chen HY. Nanoelectrochemical architectures for high-spatial-resolution single cell analysis. Sci. China. Chem. 2017, 60, 1277-1284. Zhou S, Peng X, Xu HY, Qin Y, Jiang DC*, Qu JL*, Chen HY. Fluorescence lifetime-resolved ion-selective nanospheres for simultaneous imaging of calcium ion in mitochondria and lysosomes. Anal. Chem. 2018, 90, 7982-7988. Xia J, Zhou JY, Zhang RG, Jiang DC, Jiang DP*. Gold-coated polydimethylsiloxane microwells for high-throughput electrochemiluminescence analysis of intracellular glucose at single cells. Anal. Bioanal. Chem. 2018, 410, 4787-4792. Pan RR, Xu MC, Burgess JD, Jiang DC*, Chen HY. Direct electrochemical observation of glucosidase activity in isolated single lysosomes from a living cell. Proc. Natl. Acad. Sci. U.S.A. 2018, 115, 4087-4092. Gao TB, Zhang JJ, Yan RQ, Cao DK*, Jiang DC*, Ye DJ*. Aggregation-induced electrochemiluminescence from a cyclometalated iridium(III) complex. Inorg. Chem. 2018, 57, 4310-4316. Xu HY, Zhou S, Jiang DC*, Chen HY. Cholesterol oxidase/triton X-100 parked microelectrodes for the detection of cholesterol in plasma membrane at single cells. Anal. Chem. 2018, 90, 1054-1058. Zhang JJ, Zhou JY, Pan RR, Jiang DC*, Burgess JD, Chen HY. New frontiers and challenges for single-cell electrochemical analysis. ACS Sens. 2018, 3, 242-250.