Issue 6, 2018

Omics approaches for subcellular translation studies

Abstract

Compartmentalized translation allows rapid synthesis of proteins in targeted cellular locations. Microarray and RNA sequencing combined with physical subcellular separation methods have enabled extensive charting of subcellular transcriptomes. However, the extent of translating these local messages into protein remains relatively understudied at the genome-wide level. Here we review omics methods currently available for these studies, placing special attention on methods allowing cell-specific and subcellularly restricted analysis.

Graphical abstract: Omics approaches for subcellular translation studies

Article information

Article type
Review Article
Submitted
26 Jul 2018
Accepted
10 Oct 2018
First published
10 Oct 2018

Mol. Omics, 2018,14, 380-388

Omics approaches for subcellular translation studies

I. Koppel and M. Fainzilber, Mol. Omics, 2018, 14, 380 DOI: 10.1039/C8MO00172C

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