Açaí (Euterpe oleracea Mart.) seed extract protects against hepatic steatosis and fibrosis in high-fat diet-fed mice: Role of local renin-angiotensin system, oxidative stress and inflammation
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Keywords
Euterpe oleracea Mart.
Polyphenols
Obesity
Hepatic steatosis
Fibrosis
Renin-angiotensin system
Abbreviations
ACE
angiotensin-converting enzyme
ANG 1-7
angiotensin 1-7
ANG II
angiotensin II
ANOVA
one-way analysis of variance
ASE
Açaí seed extract
AT1r
angiotensin II type 1 receptor
AT2r
angiotensin II type 2 receptor
CAT
catalase
CEUA
ethics Committee for Experimental Animals Use and Care
ENA
enalapril
GPx
glutathione peroxidase
HFD
high-fat diet
HPLC
high- performance liquid chromatography
MDA
malondialdehyde
NAFLD
nonalcoholic fatty liver disease
NASH
nonalcoholic steatohepatitis
NF-kB
nuclear factor-kB
RAS
renin-angiotensin system
ROS
reactive oxygen species
SEM
standard error measure
SOD
superoxide dismutase
TG
triacylglycerol
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