In injured intervertebral discs, disruptions in fibre organization and in cellular contractility result in a fibrotic phenotype and progressive tissue degeneration.
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DiStefano, T.J., Illien-Jünger, S. & Iatridis, J.C. Homeostasis disrupted by strain mechanosensing. Nat Biomed Eng 3, 951–952 (2019). https://doi.org/10.1038/s41551-019-0491-3
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DOI: https://doi.org/10.1038/s41551-019-0491-3
