Balancing Act: Cell Polarity and Shape Compete to Ensure Robust Development

doi:10.1016/j.devcel.2019.11.008

Developmental Cell

Volume 51, Issue 5, 2 December 2019, Pages 545-547

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In this issue of Developmental Cell, Niwayama et al. (2019) describe a model in which cell polarity and cell shape compete to determine the orientation of cell division in the pre-implantation mouse embryo. This model explains how simple cell-intrinsic rules lead to robust tissue-level morphogenesis and lineage segregation.

Developmental Cell

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Balancing Act: Cell Polarity and Shape Compete to Ensure Robust Development