Trends in Cancer
Volume 5, Issue 12, December 2019, Pages 755-756
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Science & Society
Migrastatics: Redirecting R&D in Solid Cancer Towards Metastasis?

https://doi.org/10.1016/j.trecan.2019.10.011Get rights and content

The concept of 'migrastatics' allows the development of a new drug class that is neither cytotoxic nor antiproliferative but is solely directed towards inhibition of cancer cell motility. Given that the regulatory pathway is open, and migrastatic candidates have been described, it is the right time to enter a new era of antimetastatic treatment.

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Acknowledgments

J.B. and D.R. are supported by Czech Science Foundation grant 18-15684J, the Ministry of Education, Youth, and Sports of the Czech Republic within the LQ1604 National Sustainability Program II (Project BIOCEV-FAR), and by project ‘Center for Tumor Ecology – Research of the Cancer Microenvironment Supporting Cancer Growth and Spread’ (CZ.02.1.01/0.0/0.0/16_019/0000785) supported by the Operational Programme Research, Development, and Education. V.S.M. was supported by Cancer Research UK (CRUK)

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