A new sesquiterpenoid dimer, lindenanolide I (1), and two new butanolides, (2E,3R,4S)-2-dodecylinene-3-hydroxy-4-ethoxy-4-methylbutanolide (3) and (2E,3R,4S)-2-tetradecylinene-3-hydroxy-4-ethoxy-4-methylbutanolide (4), together with five known compounds (2, 5–8), were isolated from the roots of Lindera chunii. The structures of these compounds were elucidated on the basis of extensive spectroscopic analysis and by comparison of the data with those of related secondary metabolites. The absolute configuration of 1 was identified by electronic circular dichroism (ECD) analysis. Compounds 5–8 were isolated from this plant for the first time.
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Acknowledgment
This work was funded by National Natural Science Fund (81872418), Shanghai Natural Science Foundation (18ZR1431700), Shanghai Municipal Health and Family Planning Commission Project (201540027, 20174Y0232, 20174Y0236, and 20184Y0104), the Seed Fund Program of Shanghai University of Medicine & Health Sciences (HSMF-17-22-031, SFP-18-21-15-003, and SPF-18-20-15-001), the Municipal Human Resources Development Program for Outstanding Young Talents in Medical and Health Sciences in Shanghai (2017YQ048), Shanghai Putuo District Municipal Commission of Health Research Fund (KW-2017-04), and Shanghai Fengxian District Science and Technology Project (20181601).
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Published in Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2019, pp. 921–923.
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Li, Y., Wen, S., Yang, H. et al. Chemical Constituents of the Roots of Lindera chunii. Chem Nat Compd 55, 1069–1072 (2019). https://doi.org/10.1007/s10600-019-02896-0
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DOI: https://doi.org/10.1007/s10600-019-02896-0