Phytochemical investigation of the fungus Monascus ruber led to the isolation of one new alkaloid derivative, namely ruberpyrrole (1). The structures were established by extensive spectroscopic characterization and the reported data.
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T. Akihisa, H. Tokuda, K. Yasukawa, M. Ukiya, A. Kiyota, N. Sakamoto, T. Suzuki, N. Tanabe, and H. Nishino, J. Agric. Food Chem., 53, 562 (2005).
A. Endo, J. Antibiot., 32, 852 (1979).
Y. Kohama, S. Matsumoto, T. Mimura, N. Tanabe, A. Inada, and T. Nakanishi, Chem. Pharm. Bull., 35, 2484 (1987).
D. Heber, I. Yip, J. M. Ashley, D. A. Elashoff, R. M. Elashoff, and V. L. W. Go, Am. J. Clin. Nutr., 69, 231 (1999).
P. J. Blanc, M. O. Loret, and G. Goma, Biotechnol. Lett., 17, 291 (1995).
C. Li, Y. Zhu, Y. Wang, J. S. Zhu, J. Chang, and D. Kritchevsky, Nutr. Res., 18, 71 (1998).
R. E. Mudgett, Monascus, in: Natural Food Colorants: Science and Technology, G. J. Lauro and F. J. Francis (Eds.), Marcel Dekker, New York, 2000, p. 31.
K. Tsuji, T. Ichikawa, N. Tanabe, S. Abe, S. Tarui, and Y. Nakagawa, Nippon. Nogeikagaku Kaishi, 66, 1241 (1992).
A. Endo, J. Med. Chem., 28, 401 (1985).
L. Martinokova, P. Juzlova, and D. Vesely, J. Appl. Bacteriol., 79, 609 (1995).
H. C. Wong and Y. S. Bau, Plant Physiol., 60, 578 (1977).
T. Akihisa, S. Mafune, M. Ukiya, Y. Kimura, K. Yasukawa, T. Suzuki, H. Tokuda, N. Tanabe, and T. Fukuoka, J. Nat. Prod., 67, 479 (2004).
M. J. Cheng, M. D. Wu, I. S. Chen, and G. F. Yuan, Chem. Pharm. Bull., 56, 394 (2008).
S. Jongrungruangchok, P. Kittakoop, B. Yongsmith, R. Bavovada, S. Tanasupawat, N. Lartpornmatulee, and Y. Thebtaranonth, Phytochemistry, 65, 2569 (2004).
Z. Huang, Y. Xu, L. Li, and Y. Li, J. Agric. Food Chem.,56, 112 (2008).
P. Juzlova, T. Rezanka, L. Martinkova, and V. Kren, Phytochemistry, 43, 151 (1996).
D. Wild, G. Toth, and H. U. Humpf, J. Agric. Food Chem., 50, 3999 (2002).
M. D. Wu, M. J. Cheng, G. F. Yuan, Y. J. Yech, and I. S. Chen, Acta Chim Slov., 57, 305 (2010).
Acknowledgment
The authors thank Senior Technician Mrs. Chyi-Jia Wang of Center for Resources, Research and Development (CRRD) of Kaohsiung Medical University (KMU) for measuring the 2D NMR data. This work was kindly supported by the Food Industry Research and Development Institute (FIRDI) from a Grant of the Ministry of Economic Affairs of the Republic of China.
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Published in Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2019, pp. 945–946.
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Cheng, MJ., Wu, MD., Lee, TH. et al. A New Pyrrole Compound from Monascus ruber. Chem Nat Compd 55, 1098–1100 (2019). https://doi.org/10.1007/s10600-019-02903-4
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DOI: https://doi.org/10.1007/s10600-019-02903-4