Developmental Cell
Volume 51, Issue 3, 4 November 2019, Pages 295-296
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Homolog Pairing at the Push of a Button

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Homologous chromosomes pair in somatic cells in Drosophila, but how this occurs is poorly understood. In this issue of Developmental Cell, Viets et al. (2019) show that proteins and chromatin structure mediate pairing and argue against a DNA sequence-based mechanism.

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