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Diagnostics

DNA-based computation for multiple biomarkers

DNA-based molecular computation allows for the simultaneous detection of multiple types of biomarker, as shown for the accurate identification of prostate cancer in serum samples on the basis of specific RNAs, proteins and small molecules.

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Fig. 1: DNA-encoded multidimensional molecular classifiers applied to the identification of prostate cancer in serum samples.

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Correspondence to Hao Yan.

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Yu, L., Yan, H. DNA-based computation for multiple biomarkers. Nat. Biomed. Eng 7, 1535–1536 (2023). https://doi.org/10.1038/s41551-023-01161-8

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