A chemical study on the n-BuOH-soluble fraction of the 95% EtOH extract of rice fermented with the endophytic fungus Annulohypoxylon nitens has resulted in the isolation of one new natural pyrrole derivative, designated as nitenspyrrole (1), together with 3 known compounds, taraxasterol (2), oleanolic acid (3), and β-sitostenone (4). Their structures were elucidated by spectroscopic analyses including 1D and 2D NMR experiments, and by ESI-MS.
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Acknowledgment
This work was kindly supported by the Ministry of Science and Technology, R.O.C. (MOST-108-2320-B-080-002-, MOST-109-2622-E-080-001-, and MOST-110-2320-B-080-001-). The authors thank Senior Technician Mrs. Chyi Jia Wang of the Center for Resources, Research, and Development (CRRD) of Kaohsiung Medical University for measuring the 2D NMR data.
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Published in Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2023, pp. 973–974.
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Wu, MD., Chen, JJ. & Cheng, MJ. Constituents from the Endophytic Fungus of Annulohypoxylon nitens. Chem Nat Compd 59, 1154–1156 (2023). https://doi.org/10.1007/s10600-023-04215-0
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DOI: https://doi.org/10.1007/s10600-023-04215-0