A new compound, penicilliumone A (1) was isolated from Penicillium sp. HT-G-8, a fungal endophyte of Tripterygium hypoglaucum. The structure of 1 was elucidated by IR, MS, 1D and 2D NMR spectra. Monoamine oxidase (MAO), acetylcholinesterase (AChE) and phosphoinositide 3-kinase (PI3K) inhibitory activities of 1 were also tested.
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Acknowledgment
This work was supported by the National Natural Science Foundation of China (No. 22267011), Demonstration Project of Haizhi Plan provided by Gansu Science and Technology Association (No. GSHZSF2023-03), the Industrial support plan project of colleges and universities in Gansu Province (No. 2022CYZC-29) and Science and Technology Plan Project of Wenzhou, China (2022Y0872).
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Published in Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2023, pp. 971–972.
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Zhang, T., Yang, ZD., Gou, WB. et al. A New Compound from Penicillium sp. HT-G-8, a Fungal Endophyte of Tripterygium hypoglaucum. Chem Nat Compd 59, 1151–1153 (2023). https://doi.org/10.1007/s10600-023-04214-1
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DOI: https://doi.org/10.1007/s10600-023-04214-1