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Protein design

Illuminating enzyme design using deep learning

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From humans designing machines, to machines designing biology, deep learning is turning the tables for assisted exploration of biologically active and diverse protein designs. Now, a deep-learning-based strategy has been used to design artificial enzymes that catalyse a light-emitting reaction.

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Fig. 1: De novo enzyme generation.

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Correspondence to Kevin K. Yang.

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Dallago, C., Yang, K.K. Illuminating enzyme design using deep learning. Nat. Chem. 15, 749–750 (2023). https://doi.org/10.1038/s41557-023-01218-w

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