Data and code availability
Coordinates for the structural models of EC18–RNaseHII and EC18(rGMP)–RNaseHII(E17A) have been deposited to the Protein Data Bank under PDB accession numbers 7UWE and 7UWH, respectively. The cryo-EM density maps for EC18–RNaseHII and EC18(rGMP)–RNaseHII(E17A) have also been deposited to the Electron Microscopy Data Bank under accession number EMD-26830 and EMD-26832, respectively. All deposited data is publicly available as of the date of publication.
This paper does not report the original code.
Any additional information required to reanalyze the data reported in this paper is available from the lead contact upon request.