Structure
Volume 31, Issue 4, 6 April 2023, Pages 369-371
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We con-dense if we want to; We can’t leave AZUL outside

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In this issue of Structure, Buel et al. (2023) combined NMR data with AlphaFold2 to map out the interaction between the AZUL domain of ubiquitin ligase E6AP and UBQLN1/2 UBA. The authors demonstrated that this interaction enhances the self-association of the helix neighboring UBA and enables E6AP to localize to UBQLN2 droplets.

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