YcaO enzymes are able to catalyze a diverse set of reactions and have found industrial applications. New biochemical data provide the first direct evidence for the unified reaction mechanism proposed a decade ago and will inform future enzyme engineering efforts.
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Koehnke, J. Caught in the act. Nat Chem Biol 19, 7–8 (2023). https://doi.org/10.1038/s41589-022-01180-7
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DOI: https://doi.org/10.1038/s41589-022-01180-7