Continuing Medical Education (CME)/MOC ActivitiesCME Exam 2: The Limiting Reagent for Peristalsis
Section snippets
Question 1
Which of the following is not known to cause postoperative ileus?
- a.
Hypokalemia.
- b.
Excessive intraoperative manipulation of the bowel.
- c.
Anesthesia and analgesic medications.
- d.
Mechanical obstruction.
Question 2
How does force generation in peristalsis work at a molecular level?
- a.
ATP-dependent cyclic interactions between myosin heads and actin filaments.
- b.
Generation of cyclic AMP by G-protein–coupled receptors.
- c.
Release of Ca2+ from the sarcoplasmic reticulum
- d.
Phosphorylation of PIP2 to PIP3 by PI3 kinases.
Question 3
What is the most commonly mutated gene seen in chronic intestinal pseudo-obstruction?
- a.
MYH11 – smooth muscle myosin heavy chain 11.
- b.
ACTG2 – smooth muscle actin gamma 2.
- c.
RAD21 – RAD21 cohesin complex component.
- d.
SGOL1 – Shugoshin-like 1.
Question 4
What is a typical timeline for return of bowel function after an intra-abdominal surgical procedure?
- a.
Colonic motility is typically restored within 48 hours.
- b.
Postoperative ileus lasting >72 hours is considered pathologic.
- c.
Small bowel motility usually returns within 8 hours.
- d.
Passing a bowel movement within 24 hours of the surgical procedure is expected.